Abstract

On Thursday, August 21, 1862, Edmond and Jules de Goncourt registered in their Journal a short entry on the nature of life: “Qu’est-ce que la vie? L’usufruit d’une agrégation de molecules”—What is life? The usufruct of an aggregation of molecules. Although the extraordinary chronicles of the social and cultural life of the Second French Empire written by the Goncourt brothers includes names of their most distinguished contemporaries, the writers, artists, politicians and socialites they befriended outnumber by far the scientists. It is almost certain that they were never close to Felix Dujardin, a distinguished microbiologist and member of the French Academy of Sciences. In 1835, Dujardin had started crushing ciliates under the microscope and observed that the tiny cells exuded a jellylike substance, which he described as a “gelée vivante” and was eventually named “protoplasm” by Johann E. Purkinje and Hugo von Mohl. The small note written by the Goncourts in their journal is an indica