How to Investigate the Effects of Groups on Changes in Longitudinal Patient-Reported Outcomes and Response Shift Using Rasch Models

Frontiers in Psychology 11 (2020)
  Copy   BIBTEX

Abstract

In order to investigate patients’ experience of healthcare, repeated assessments of patient-reported outcomes are increasingly performed in observational studies and clinical trials. Changes in PRO can however be difficult to interpret in longitudinal settings as patients’ perception of the concept being measured may change over time, leading to response shift and possibly to erroneous interpretation of the observed changes in PRO. Several statistical methods for response shift analysis have been proposed, but they usually assume that response shift occurs in the same way in all individuals within the sample regardless of their characteristics. Many studies aim at comparing the longitudinal change of PRO into two groups of patients. The group variable could have an effect on PRO change but also on response shift effect and the perception of the questionnaire at baseline. In this paper, we propose to enhance the ROSALI algorithm based on Rasch Measurement Theory for the analysis of longitudinal PRO data to simultaneously investigate the effects of group on item functioning at the first measurement occasion, on response shift and on changes in PRO over time. ROSALI is subsequently applied to a longitudinal dataset on change in emotional functioning in patients with breast cancer or melanoma during the year following diagnosis. The use of ROSALI provides new insights in the analysis of longitudinal PRO data.

Links

PhilArchive



    Upload a copy of this work     Papers currently archived: 93,296

External links

Setup an account with your affiliations in order to access resources via your University's proxy server

Through your library

Similar books and articles

Longitudinal Study Designs.Stewart J. Anderson - 2019 - In Pranee Liamputtong (ed.), Handbook of Research Methods in Health Social Sciences. Springer Singapore. pp. 603-622.

Analytics

Added to PP
2020-12-24

Downloads
3 (#1,729,579)

6 months
6 (#587,658)

Historical graph of downloads
How can I increase my downloads?

Citations of this work

No citations found.

Add more citations

References found in this work

No references found.

Add more references