We analyzed stable patients’ views regarding synthetic biology in general, the medical application of synthetic biology, and their potential participation in trials of synthetic biology in particular. The aim of the study was to find out whether patients’ views and preferences change after receiving more detailed information about synthetic biology and its clinical applications. The qualitative study was carried out with a purposive sample of 36 stable patients, who suffered from diabetes or gout. Interviews were transcribed verbatim, translated and fully (...) anonymized. Thematic analysis was applied in order to examine stable patients’ attitudes towards synthetic biology, its medical application, and their participation in trials. When patients were asked about synthetic biology in general, most of them were anxious that something uncontrollable could be created. After a concrete example of possible future treatment options, patients started to see synthetic biology in a more positive way. Our study constitutes an important first empirical insight into stable patients’ views on synthetic biology and into the kind of fears triggered by the term “synthetic biology.” Our results show that clear and concrete information can change patients’ initial negative feelings towards synthetic biology. Information should thus be transmitted with great accuracy and transparency in order to reduce irrational fears of patients and to minimize the risk that researchers present facts too positively for the purposes of persuading patients to participate in clinical trials. Potential participants need to be adequately informed in order to be able to autonomously decide whether to participate in human subject research involving synthetic biology. (shrink)

Descartes' morals are often considered a marginal epiphenomenon not only with respect to his metaphysics, but also in regard to the ethical theories that preceded and followed it, that is, broadly Aristotle's eudaimonism, Kantian deontologism and Mill's utilitarianism. I argue in this paper that Descartes' morals do not play a merely subaltern role in his metaphysics, as is often claimed. I first present the specificity and the evolution of his morals by giving an account of his provisory and perfect morals. (...) Second I argue that a close reading of important passages from his correspondence and his treatise on the Passions of the Soul indicates that Descartes develops a third kind of morals based on the virtue-passion of generosity. The last part of the paper discusses Descartes' own treatment of the passions and suggests against the standard view that Descartes' concern is also the veri hominess , and ultimately the generosi hominess . South African Journal of Philosophy Vol. 25(2) 2006: 177-188. (shrink)

In this paper, following an elementary line of thought which somewhat differs from the usual one, we prove once more that any deterministic theory predictively equivalent to quantum mechanics unavoidably exhibits a contextual character. The purpose of adopting this perspective is that of paving the way for a critical analysis of the use of counterfactual arguments when dealing with nonlocal physical processes.

This paper explores the importance of hope as a determining factor for patients to participate in first-in-human trials for synthetic biology therapies. This paper focuses on different aspects of hope in the context of human health and well-being and explores the varieties of hope expressed by patients. The research findings are based on interview data collected from stable gout and diabetes patients. Three concepts of hope have emerged from the interviews: hope as certainty ; hope as reflective uncertainty ; hope (...) as self-therapy. The purpose of the paper is twofold. First, it aims to underline the significance of hope in patients’ medical decision-making, as well as the beneficence of hope for patients’ well-being, and for progress in research. Second, it shows how philosophical investigations—in particular Descartes—explore the phenomenon of hope and provide medical empirical research with profitable insights and tools. (shrink)

Cette etude est une analyse des uvres de Nietzsche (1878-1885) ayant trait non seulement a sa critique du christianisme en general et a son interpretation de la Mort de Dieu en particulier, mais aussi a l'elaboration de ses anti-ideals.

The use of eHealth components in healthcare is often viewed in the context of disruptive change and ethical pitfalls. We focus on interpersonal relationships between physicians, patients, and care providers and show that positive changes (also) occur within this context.

Vulnerability and politics are among the relevant and key topics of discussion in the Ethiopian healthcare context. Attempts by the formal bioethics structure in Ethiopia to deliberate on ethical issues relating to vulnerability and politics in healthcare have been limited, even though the informal analysis of bioethical issues has been present in traditional Ethiopian communities. This is reflected in religion, social values, and local moral underpinnings. Thus, the aim of this paper is to discuss the bioethical implications of vulnerability and (...) politics for healthcare in Ethiopia and to suggest possible ways forward. First, we will briefly introduce what has been done to develop bioethics as a field in Ethiopia and what gaps remain concerning its implementation in healthcare practice. This will give a context for our second and main task – analyzing the healthcare challenges in relation to vulnerability and politics and discussing their bioethical implications. In doing so, and since these two concepts are intrinsically broad, we demarcate their scope by focusing on specific issues such as poverty, gender, health governance, and armed conflicts. Lastly, we provide suggestions for the ways forward. (shrink)

Documentation on Nietzsche's teaching at the University in Basel.

Oral healthcare is attracting much attention after decades of neglect from policymakers. Recent studies have shown a strong association between oral and overall health, which can lead to serious health problems. Availability of oral healthcare services is an essential part of ensuring universal healthcare coverage. More importantly, current gaps in its accessibility by minority or marginalized population groups are crucial public health as well as ethical concerns. One notable effort to address this issue comes from Non-Governmental Organizations (NGOs), which offer (...) oral healthcare services for non-insured refugees. However, the challenge remains that these care services are not comprehensive, which has implications for the refugees’ oral and general health. In this article, we discuss this complex issue in the German healthcare context by including ethical reflections. Therefore, the purpose of this article is to discuss the ethical challenges related to oral healthcare services provided by NGOs for refugees in Germany. First, we will introduce the general oral healthcare context worldwide and in Germany. Second, we will provide a general description of the oral healthcare services provided by NGOs for refugees in Germany, as well as an overview of existing gaps. This will provide us with the context for our third and most important task—discussing the ethical implications of the gaps. In doing so, and since the ethical implications can be several, we demarcate the scope of our analysis by focusing on the specific ethical issues of justice, harm, and autonomy. Finally, we offer some recommendations for how to move forward. (shrink)

The place (or absence) of God in Nietzsche's thought remains central and controversial. Nietzsche's proclamation of 'the death of God' is one of the most famous (and parodied) slogans in modern philosophy, seeming to encapsulate the nineteenth-century loss of religious faith in the affirmation that God has "turned out to be our oldest lie" and yet the nature of Nietzsche's own 'theology' is far from clear. This volume engages with Nietzsche's arguments about God, theology, and religion. The volume extends the (...) discussion to an engagement of Nietzsche with alternative models of God, with ancient Greek religions, and with discussions of diversity (race, class, gender, sex) in dis/conjunction with religion. The chapters examine Nietzsche's genealogy of religion and his claims about the place of God and theology in the history of Western thought ("that faith of the Christians, which was also Plato's faith"), as well as his engagements with alternative conceptions of God. The volume also examines the historical and contemporary reception of Nietzsche's arguments about God by religious and non-religious thinkers, asking to what extent Nietzsche's philosophy of God speaks to the challenges of today's globalized philosophy and religion. (shrink)

Name der Zeitschrift: Klio Jahrgang: 97 Heft: 1 Seiten: 360-372.