_Systematic public vaccination constitutes a tremendous health success, perhaps the greatest achievement of biomedicine so far. There is, however, room for improvement. Each year, 1.5 million deaths could be avoided with enhanced immunisation coverage. In recent years, many countries have introduced mandatory childhood vaccination programmes in an attempt to avoid deaths. In Norway, however, the vaccination programme has remained voluntary. Our childhood immunisation programme covers protection for twelve infectious diseases, and Norwegian children are systematically immunised from six weeks to sixteen (...) years of age. In this article, we address the question of whether our country, Norway, should make the childhood vaccination programme mandatory. This question has received considerable public attention in the media, yet surprisingly little academic discussion has followed. The aim of the article is to systematically discuss whether it is morally justified to introduce a mandatory childhood vaccination programme in Norway. Our discussion proceeds as follows: We begin by presenting relevant background information on the history of vaccines and the current Norwegian childhood vaccination programme. Next, we discuss what we consider to be the most central arguments against mandatory childhood vaccination: the argument from the standpoints of parental rights, bodily integrity, naturalness, mistrust, and immunisation coverage. After that, we examine the central arguments in favour of mandatory childhood vaccination from the standpoints of harm, herd immunity, and as a precautionary strategy. We conclude that there are convincing moral arguments in favour of adopting a policy of mandatory childhood vaccination in Norway._ _Keywords_: autonomy, harm principle, herd immunity, parental rights, precautionary approach. (shrink)

It is well known that there has been a steady and significant underrepresentation of women in philosophy on different professional levels. Numerous hypotheses explaining this underrepresentation have been suggested, but empirical analyses are not yet extensive. In particular, studies of the phenomenon in different countries are nonexistent. In this paper, we present findings from an exploratory study in which we analyze the interests, abilities, beliefs, attitudes, perceptions, and goals of bachelor’s students in a semester-long philosophy of science course at a (...) major German university. We furthermore make the first attempt to compare women-only learning environments with mixed-gender learning environments. Our results suggest that while there are generally some gender differences regarding interests, abilities, beliefs, attitudes, perceptions, and goals of students in the classroom, most of the hypotheses we explore to explain dropout rates by gender differences cannot be supported. We conclude that possible factors leading to the underrepresentation of women in philosophy in Germany might be found in the social and institutional environment within which philosophy is taught. (shrink)

Name der Zeitschrift: Das Mittelalter Jahrgang: 23 Heft: 1 Seiten: 1-6.

Name der Zeitschrift: Der Islam Jahrgang: 93 Heft: 2 Seiten: 614-617.

In public debate GMPs are oftenreferred to as being unnatural or a violationof nature. Some people have serious moralconcerns about departures from what is natural.Others are concerned about potential risks tothe environment arising from the combination ofhereditary material moving across naturalboundaries and the limits of scientificforesight of long-term consequences. To addresssome of these concerns we propose that anadditional element in risk assessment based onthe concept of familiarity should beintroduced. The objective is to facilitatetransparency about uncertainties inherent inthe risk assessment of (...) the GMP. Familiarityconventionally involves data and experiencerelating to the plant species and the ecosystemin question. We would like to extend thisconcept to the molecular level of plantbreeding and suggest that GMP characteristicsshould be compared to a reference baselinedetermined by conventional breeding techniques.Three GMPs are ranked according to familiarityat the plant and ecosystem level and themolecular level. The approach may help tointegrate discussion of the scientificarguments and moral questions raised in thedebate about GMOs by providing an operationalscheme within which moral concerns are broughtwithin the framework of science-based riskassessment. (shrink)

In cognitive research, metaphors have been shown to help us imagine complex, abstract, or invisible ideas, concepts, or emotions. Contributors to this book argue that metaphors occur not only in language, but in audio visual media well. This is all the more evident in entertainment media, which strategically "sell" their products by addressing their viewers’ immediate, reflexive understanding through pictures, sounds, and language. This volume applies cognitive metaphor theory to film, television, and video games in order to analyze the embodied (...) aesthetics and meanings of those moving images. (shrink)

The objects we encounter in ordinary life and scientific practice - cars, trees, people, houses, molecules, galaxies, and the like - have long been a fruitful source of perplexity for metaphysicians. The Structure of Objects gives an original analysis of those material objects to which we take ourselves to be committed in our ordinary, scientifically informed discourse. Koslicki focuses on material objects in particular, or, as metaphysicians like to call them "concrete particulars", i.e., objects which occupy a single region of (...) space-time at each time at which they exist and which have a certain range of properties that go along with space-occupancy, such as weight, shape, color, texture, and temperature. The Structure of Objects focuses in particular on the question of how the parts of such objects, assuming that they have parts, are related to the wholes which they compose. (shrink)

Normativism in the theory of meaning and content is the view that linguistic meaning and/or intentional content are essentially normative. As both normativity and its essentiality to meaning/content can be interpreted in a number of different ways, there is now a whole family of views laying claim to the slogan “meaning/content is normative”. In this essay, we discuss a number of central normativist theses, and we begin by identifying different versions of meaning normativism, presenting the arguments that have been put (...) forth for and against them. (shrink)

Does the notion of ground, as it has recently been employed by metaphysicians, point to a single unified phenomenon? Jonathan Schaffer holds that the phenomenon of grounding exhibits the unity characteristic of a single genus. In defense of this hypothesis, Schaffer proposes to take seriously the analogy between causation and grounding. More specifically, Schaffer argues that both grounding and causation are best approached through a single formalism, viz., that utilized by structural equation models of causation. In this paper, I present (...) several concerns which suggest that the structural equation model does not transfer as smoothly from the case of causation to the case of grounding as Schaffer would have us believe. If it can in fact be shown that significant differences surface in how the formalism in question applies to the two types of phenomena in question, Schaffer’s attempt at establishing an analogy between grounding and causation has thereby been weakened and, as a result, the application of the Unity Hypothesis to the case of grounding once again stands in need of justification. (shrink)

Implicit bias is one of the most successful cases in recent memory of an academic concept being translated into practice. Its use in the National Science Foundation ADVANCE program—which seeks to promote gender equality in STEM careers through institutional transformation—has raised fundamental questions about organizational change. How do advocates translate theories into practice? What makes some concepts more tractable than others? What happens to theories through this translation process? We explore these questions using the ADVANCE program as a case study. (...) Using an inductive, theory-building approach and combination of computational and qualitative methods, we investigate how the concept of implicit bias was translated into practice through the ADVANCE program and identify five key features that made implicit bias useful as a change framework in the academic STEM setting. We find that the concept of implicit bias works programmatically because it is demonstrable, relatable, versatile, actionable, and impartial. While enabling the concept’s diffusion, these characteristics also limit its scope. We reflect on implications for gender theories of organizational change and for practitioners. (shrink)

In _Form, Matter, Substance_, Kathrin Koslicki defends a hylomorphic analysis of concrete particular objects (e.g., living organisms). The Aristotelian doctrine of hylomorphism holds that those entities that fall under it are compounds of matter (hulē) and form (morphē or eidos). Koslicki argues that a hylomorphic analysis of concrete particular objects is well-equipped to compete with alternative approaches when measured against a wide range of criteria of success. A successful application of the doctrine of hylomorphism to the special case of (...) concrete particular objects, however, hinges on how hylomorphists conceive of the matter composing a concrete particular object, its form, and the hylomorphic relations which hold between a matter-form compound, its matter and its form. Through the detailed answers to these questions Koslicki develops in this book, matter-form compounds, despite their metaphysical complexity, emerge as occupying the privileged ontological status traditionally associated with substances, due in particular to their high degree of unity. (shrink)

This inaugural lecture, delivered on 17 November 2021 at the University of Neuchâtel, addresses the question: Are material objects analyzable into more basic constituents and, if so, what are they? It might appear that this question is more appropriately settled by empirical means as utilized in the natural sciences. For example, we learn from physics and chemistry that water is composed of H2O-molecules and that hydrogen and oxygen atoms themselves are composed of smaller parts, such as protons, which are in (...) turn composed of yet smaller parts, such as quarks, and so on. While the question at the center of this lecture might thus appear to fall more appropriately into the empirical domain of natural science, I argue that metaphysics in fact has an important role to play in determining how best to answer the question before us. More concretely, I propose that the Aristotelian doctrine of hylomorphism, when appropriately interpreted, provides the best metaphysical answer to the question of whether and how material objects are analyzable into more basic constituents. Hylomorphism holds that those entities to which this doctrine applies are, in some sense, compounds of matter (“hylē”) and form (“morphē” or “eidos”). Thus, the title of this lecture, “Form, Matter, Substance”, refers to the claim that lies at the center of the doctrine of hylomorphism, as applied to the domain of material objects, namely that sensible substances are the result of combining matter and form in the right sort of way; or, for short, “form + matter = substance”. I begin in Section II by providing some historical background which brings out Aristotle’s motivations for proposing the doctrine of hylomorphism in the context of his analysis of change. Section III turns to some of the main features of the contemporary hylomorphic theory I have defended especially in Koslicki (2008) and Koslicki (2018). Section IV discusses some challenging questions concerning artifacts which arise for both hylomorphic and other approaches to the metaphysics of concrete particular objects. Section V concludes by summarizing why, as contemporary metaphysicians, we should prefer a hylomorphic theory over its competitors as an analysis of concrete particular objects that is compatible with our current scientific understanding of the world. (shrink)

Rooftop gardens, rooftop greenhouses and indoor farms have been established or planned by activists and private companies in Berlin. These projects promise to produce a range of goods that could have positive impacts on the urban setting but also carry a number of risks and uncertainties. In this early innovation phase, the relevant stakeholders’ perceptions and social acceptance of ZFarming represent important preconditions for success or failure of the further diffusion of this practice. We used the framework of acceptance to (...) investigate the stakeholders’ attitudes and to identify the key factors that might hinder or promote the introduction of ZFarming. The results are based on an analysis of 38 qualitative interviews conducted with key stakeholders in Berlin. As the results show, major perceived benefits of ZFarming include improved consumer awareness, education, and the creation of experimental spaces. Stakeholders further perceive opportunities for resource savings, new business models, repurposing of abandoned buildings and improved aesthetics. Major perceived risks are associated with growing techniques that are considered “unnatural”, health risks, conflicts with images of traditional agriculture, the rejection of animal production in urban areas, the risk of projects being too expensive and too complex or being implemented too early, i.e. before the mechanisms are fully understood. The analysis further reveals which contextual factors—political, legal, market-related, spatial or societal—might negatively or positively influence ZFarming acceptance. (shrink)

At first glance the three eukaryotic protein translocation machineries – the ER‐associated degradation (ERAD) transport apparatus of the endoplasmic reticulum, the peroxisomal importomer and SELMA, the pre‐protein translocator of complex plastids – appear quite different. However, mechanistic comparisons and phylogenetic analyses presented here suggest that all three translocation machineries share a common ancestral origin, which highlights the recycling of pre‐existing components as an effective evolutionary driving force.Editor's suggested further reading in BioEssays ERAD ubiquitin ligases Abstract.

After many years of enduring the drought and famine of Quinean ontology and Carnapian meta-ontology, the notion of ground, with its distinctively philosophical flavor, finally promises to give metaphysicians something they can believe in again and around which they can rally: their very own metaphysical explanatory connection which apparently cannot be reduced to, or analyzed in terms of, other familiar idioms such as identity, modality, parthood, supervenience, realization, causation or counterfactual dependence. Often, phenomena such as the following are cited as (...) putative examples of grounding connections: systematic connections between entire realms of facts (mental/physical; moral/natural; etc.); truthmaking (e.g., the relation between the truth of the proposition that snow is white and snow’s being white); logical cases (e.g., the connection between conjunctive facts or disjunctive facts and their constituent facts); the determinate/determinable relation (e.g., the relation between something’s being maroon and its being red). I argue in this paper that classifying all of these phenomena as exhibiting grounding connections does not achieve much in the way of illumination. In fact, by treating a collection of phenomena which is in fact heterogeneous as though it were homogeneous, we have, if anything, taken a dialectical step backward. (shrink)

As meaning's claim to normativity has grown increasingly suspect the normativity thesis has shifted to mental content. In this paper, we distinguish two versions of content normativism: 'CE normativism', according to which it is essential to content that certain 'oughts' can be derived from it, and 'CD normativism', according to which content is determined by norms in the first place. We argue that neither type of normativism withstands scrutiny. CE normativism appeals to the fact that there is an essential connection (...) between content and correctness conditions. But, we argue, this fact is by itself normatively innocent, and attempts to add a normative dimension via the normativity of belief ultimately fail. CD normativism, in turn, falls prey to the 'dilemma of regress and idleness': the appeal to rules either leads to some form of regress of rules, or the notion of rule-following is reduced to an idle label. We conclude by suggesting that our arguments do not support naturalism: it is a mistake to assume that normativism and naturalism are our only options. (shrink)

A significant reorientation is currently under way in analytic metaphysics, away from an almost exclusive focus on questions of existence and towards a greater concentration on questions concerning the dependence of one type of phenomenon on another. Surprisingly, despite the central role dependence has played in philosophy since its inception, interest in a systematic study of this concept has only recently surged among contemporary metaphysicians. In this paper, I focus on a promising account of ontological dependence in terms of a (...) non-modal and sufficiently constrained conception of essence developed by Kit Fine. I argue that even this essentialist account is, as it stands, not fine-grained enough to recognize different varieties of dependence which ought to be distinguished even within the realm of ontology. In some cases, an entity may be ontologically dependent on its essential constituents out of which it is constructed; but in other cases, an entity may be ontologically dependent on another for a different reason. A framework which glosses over these differences does not offer a proper diagnosis of why one entity ontologically depends on another. (shrink)

In his excellent book, Four-Dimensionalism: An Ontology of Persistence and Time (Sider, 2001), Theodore Sider defends a version of four-dimensionalism which he calls the ‘stage-theory’. This paper focuses on Sider's argument from vagueness and argues that, due to the problematic nature of the argument from vagueness, Sider’s case in favor of four-dimensionalism is in the end not successful.

Considered by many to be Abraham Robinson's magnum opus, this book offers an explanation of the development and applications of non-standard analysis by the mathematician who founded the subject. Non-standard analysis grew out of Robinson's attempt to resolve the contradictions posed by infinitesimals within calculus. He introduced this new subject in a seminar at Princeton in 1960, and it remains as controversial today as it was then. This paperback reprint of the 1974 revised edition is indispensable reading for anyone interested (...) in non-standard analysis. It treats in rich detail many areas of application, including topology, functions of a real variable, functions of a complex variable, and normed linear spaces, together with problems of boundary layer flow of viscous fluids and rederivations of Saint-Venant's hypothesis concerning the distribution of stresses in an elastic body. (shrink)

Pacifists and their opponents disagree not only about moral questions, but rather often about factual questions as well—as seen when looking at the controversy surrounding the crisis in Kosovo. According to my reconstruction of pacifism, this is not surprising since the pacifist,legitimately, looks at the facts in the light of her system of value. Her opponent, in turn, looks at the facts in the light of an alternative value system, and the quarrel between the two parties about supposedly descriptive matters (...) never ceases, as there is no objective reality about the war in question that could settle the issue.In my view, the pacifist's value-laden way of looking at reality implicitly obeys three epistemic imperatives. First, the Epistemic Imperative concerning Human Nature ("Resist demonizing the other side; always try to understand the case from the other point of view"). Second, the Epistemic Imperative concerning Non-Violent Alternatives ("Always search for non-violent alternatives to military action"). Third, the Epistemic Imperative concerning Uncontrolled Escalation ("Hone your senses to the uncontrolled, irreversible side effects of military action, particularly to the danger of military escalation leading to another world war"). Objective reality has no way of telling us how far we should go in following these imperatives. Rather, we have to make the decision about how far we are going to take them ourselves. In this way, the pacifist's epistemic imperatives are comparable to Kant's regulative principles. (shrink)

This essay provides an opinionated survey of some recent developments in the literature on ontological dependence. Some of the most popular definitions of ontological dependence are formulated in modal terms; others in non-modal terms (e.g., in terms of the explanatory connective, ‘because’, or in terms of a non-modal conception of essence); some (viz., the existential construals of ontological dependence) emphasise requirements that must be met in order for an entity to exist; others (viz., the essentialist construals) focus on conditions that (...) must be satisfied in order for an entity to be the very entity it is at each time at which it exists; some are rigid, in the sense that they concern a relation between particular entities; others are generic, in the sense that they involve only a relation between an entity and some entities or other, which bear certain characteristics. I identify three potential measures of success with respect to which these different definitions of ontological dependence can be evaluated and consider the question of how well they in fact meet these desiderata. I end by noting that certain challenges face even the most promising essentialist construals of ontological dependence. (shrink)

Emotion Review, Volume 14, Issue 1, Page 84-95, January 2022. Emotional stimuli such as images, words, or video clips are often used in studies researching emotion. New sets are continuously being published, creating an immense number of available sets and complicating the task for researchers who are looking for suitable stimuli. This paper presents the KAPODI-database of emotional stimuli sets that are freely available or available upon request. Over 45 aspects including over 25 key set characteristics have been extracted and (...) listed for each set. The database facilitates finding of and comparison between individual sets. It currently contains sets published between 1963 and 2020. A searchable online version allows users to select specific set characteristics and to find matching sets accordingly, as well as to add new published sets. (shrink)

Emotion Review, Volume 14, Issue 1, Page 84-95, January 2022. Emotional stimuli such as images, words, or video clips are often used in studies researching emotion. New sets are continuously being published, creating an immense number of available sets and complicating the task for researchers who are looking for suitable stimuli. This paper presents the KAPODI-database of emotional stimuli sets that are freely available or available upon request. Over 45 aspects including over 25 key set characteristics have been extracted and (...) listed for each set. The database facilitates finding of and comparison between individual sets. It currently contains sets published between 1963 and 2020. A searchable online version allows users to select specific set characteristics and to find matching sets accordingly, as well as to add new published sets. (shrink)

According to some phenomenologists, a tool can be experienced as incorporated when, as a result of habitual use or deliberate practice, someone is able to manipulate it without conscious effort. In this article, we specifically focus on the experience of expertise tool use in elite sport. Based on a case study of elite rope skipping, we argue that the phenomenological concept of incorporation does not suffice to adequately describe how expert tool users feel when interacting with their tools. By analyzing (...) a combination of insights gained from participant observation of 11 elite rope skippers and autoethnographic material from one former elite skipper, we take some initial steps toward the development of a more nuanced understanding of the concept of incorporation; one that is able to accommodate the experiences of expert tool users. In sum, our analyses indicate that the possibility for experiencing a tool as incorporated depends on the existence of an extraordinary kind of relationship between th... (shrink)

We design a framework for assisted normative reasoning based on Aristotelian diagrams and algorithmic graph theory which can be employed to address heterogeneous tasks of deductive reasoning. Here we focus on two problems of normative determination: we show that the algorithms used to address these problems are computationally efficient and their operations are traceable by humans. Finally, we discuss an application of our framework to a scenario regulated by the GDPR.

Concrete particular objects (e.g., living organisms) figure saliently in our everyday experience as well as our in our scientific theorizing about the world. A hylomorphic analysis of concrete particular objects holds that these entities are, in some sense, compounds of matter (hūlē) and form (morphē or eidos). The Grounding Problem asks why an object and its matter (e.g., a statue and the clay that constitutes it) can apparently differ with respect to certain of their properties (e.g., the clay’s ability to (...) survive being squashed, as compared to the statue’s inability to do so), even though they are otherwise so much alike. In this paper, I argue that a hylomorphic analysis of concrete particular objects, in conjunction with a non-modal conception of essence of the type encountered for example in the works of Aristotle and Kit Fine, has the resources to yield a solution to the Grounding Problem. (shrink)

This paper provides a detailed examination of Kit Fine’s sizeable contribution to the development of a neo‐Aristotelian alternative to standard mereology; I focus especially on the theory of ‘rigid’ and ‘variable embodiments’, as defended in Fine 1999. Section 2 briefly describes the system I call ‘standard mereology’. Section 3 lays out some of the main principles and consequences of Aristotle’s own mereology, in order to be able to compare Fine’s system with its historical precursor. Section 4 gives an exposition of (...) Fine’s theory of embodiments and goes on to isolate a number of potential concerns to which this account gives rise. In particular, I argue that Fine’s theory threatens to proliferate primitive sui generis relations of parthood and composition, whose characteristics must be stipulatively imposed on them, relative to particular domains; given its ‘superabundance’ of objects, Fine’s system far outstrips the already inflated ontological commitments of standard mereology; and there is a legitimate question as to why we should consider Fine’s primitive and sui generis relations of parthood and composition to be genuinely mereological at all, given their formal profile. These three objections lead me to conclude that we ought to explore other avenues that preserve the highly desirable, hylomorphic, features of Fine’s mereology, while avoiding its methodological and ontological excesses. (shrink)

Ce texte a déjà paru dans la revue Philosophique, 11 | 2008, 79-96 et mis en ligne ici. Nous remercions Kathrin H. Rosenfield de nous avoir autorisé à le reproduire sur RHUTHMOS. On sait qu'Hölderlin s'est délibérément opposé à la « conception régnante par rapport au monde Grec » et au classicisme de Weimar qui voit Sophocle comme le modèle de la mesure rationnelle. Déjà Hellingrath et Beissner ont signalé qu'il accentue « l'enthousiasme excentrique », c'est-à-dire, les - XVIIIe (...) siècle – Nouvel article. (shrink)

Today, many philosophers think that perceptual experiences are conscious mental states with representational content and phenomenal character. Subscribers to this view often go on to construe experience more precisely as a propositional attitude sui generis ascribing sensible properties to ordinary material objects. I argue that experience is better construed as a kind of belief ascribing 'phenomenal' properties to such objects. A belief theory of this kind deals as well with the traditional arguments against doxastic accounts as the sui generis view. (...) Moreover, in contrast to sui generis views, it can quite easily account for the rational or reason providing role of experience. (shrink)

It is common to think of essence along modal lines: the essential truths, on this approach, are a subset of the necessary truths. But Aristotle conceives of the necessary truths as being distinct and derivative from the essential truths. Such a non-modal conception of essence also constitutes a central component of the neo-Aristotelian approach to metaphysics defended over the last several decades by Kit Fine. Both Aristotle and Fine rely on a distinction between what belongs to the essence proper of (...) an object and what merely follows from the essence proper of an object. In order for this type of approach to essence and modality to be successful, we must be able to identify an appropriate consequence relation which in fact generates the result that the necessary truths about objects follow from the essential truths. I discuss some proposals put forward by Fine and then turn to Aristotle’s account: Aristotle’s central idea, to trace the explanatory power of definitions to the causal power of essences has the potential to open the door to a philosophically satisfying response to the question of why certain things are relevant, while others are irrelevant, to the nature or essence of entities. If at all possible, it would be desirable for example to have something further to say by way of explanation to such questions as ‘Why is the number 2 completely irrelevant to the nature of camels?’. (shrink)

The Assumption of Agency Theory Content Type Journal Article Category Review Pages 523-528 DOI 10.1558/jcr.v11i4.523 Authors Kathrine Elizabeth Anker, Planetary Collegium, Plymouth University, Drake Circus, Plymouth, Devon PL4 8AA, UK Journal Journal of Critical Realism Online ISSN 1572-5138 Print ISSN 1476-7430 Journal Volume Volume 11 Journal Issue Volume 11, Number 4 / 2012.

Along with many other languages, English has a relatively straightforward grammatical distinction between mass-occurrences of nouns and their countoccurrences. As the mass-count distinction, in my view, is best drawn between occurrences of expressions, rather than expressions themselves, it becomes important that there be some rule-governed way of classifying a given noun-occurrence into mass or count. The project of classifying noun-occurrences is the topic of Section II of this paper. Section III, the remainder of the paper, concerns the semantic differences between (...) nouns in their mass-occurrences and those in their count-occurrences. As both the name view and the mixed view are, in my opinion, subject to serious difficulties discussed in Section III.1,I defend a version of the predicate view. Traditionally, nouns in their singular count-occurrences are also analyzed as playing the semantic role of a predicate. How, then, does the predicate view preserve the intuitive difference between nouns in their mass- and those in their count-occurrences? I suggest, in Section III.2, that there are different kinds of predicates: mass-predicates, e.g. ‘is hair’, singular count-predicates, e.g. ‘is a hair’, and plural count-predicates, e.g. ‘are hairs’. Mass-predicates and count-predicates, in my view, are not reducible to each other. The remainder of Section III takes a closer look at the differences and interrelations between these different kinds of predicates. Mass-predicates and count-predicates differ from each other truth-conditionally, and these truth-conditional differences turn out to have interesting implications, in particular concerning the part-whole relation and our practices of counting. But mass- and count-predicates are also related to each other through systematic entailment relations; these entailment relations are examined in Section III.4. (shrink)

Hands are notoriously hard to draw. To compellingly capture their detail, proportion, and movement is generally considered a mark of an artist’s mastery of tech.

When reproductive and genetic technologies spurred an extended German policy debate, the issues at stake went beyond the technologies to include the very meaning of “ethics” and the respective roles of ethicists and of the public in thinking about ethical questions.

Beta‐oxidation of fatty acids and detoxification of reactive oxygen species are generally accepted as being fundamental functions of peroxisomes. Additionally, these pathways might have been the driving force favoring the selection of this compartment during eukaryotic evolution. Here we performed phylogenetic analyses of enzymes involved in beta‐oxidation of fatty acids in Bacteria, Eukaryota, and Archaea. These imply an alpha‐proteobacterial origin for three out of four enzymes. By integrating the enzymes' history into the contrasting models on the origin of eukaryotic cells, (...) we conclude that peroxisomes most likely evolved non‐symbiotically and subsequent to the acquisition of mitochondria in an archaeal host cell. (shrink)

_Animal Experimentation: Working Towards a Paradigm Change_ critically appraises current animal use in science and discusses ways in which we can contribute to a paradigm change towards human-biology based approaches.

In this article I will relate the kinetic sculpture Hylozoic Ground by architect Phillip Beesley and a collaborative group to theoretical and philosophical studies concerning the human subject. I will ask the deep philosophical question what is life? with the expectancy of a close relationship between ‘life’ and ‘consciousness’. Under inspiration from Yair Neuman and Søren Brier, I operate with the idea that ‘life’ and ‘consciousness’ would be directly related to communication processes in the body of both physically measurable and (...) physically immeasurable kinds. And that such communication processes are best described by modelling a hierarchy of qualitatively different, but co-dependent kinds of communication. (shrink)