Given research and public interest for conditions related to an extended lifespan, we addressed the questions of what matters and what matters most for subsequent survival past age 80. The data was drawn from the population-based and multidisciplinary Swedish OCTO Twin Study, in which a sample consisting of identical and same-sex fraternal twin pairs, followed from age 80 until death, provided detailed data on health, physical functioning, life style, personality, and sociodemographic conditions. Information concerning date of birth and death were (...) obtained from population census register. We estimated heritability using an ACE model and evaluated the role of multiple predictors for the mortality-related hazard rate using Cox regression. Our findings confirmed a low heritability of 12%. As expected, longer survival was associated with being a female, an apolipoprotein E e4 allele non-carrier, and a non-smoker. Several diseases were found to be associated with shorter survival as well as certain health conditions. Stronger grip and better lung function, as well as better vision, and better cognitive function was related to longer survival. Social embeddedness, better self-evaluated health, and life-satisfaction were also significantly associated with longer survival. After controlling for the impact of comorbidity, functional markers, and personality-related predictors, we found that sex, cerebrovascular diseases, compromised cognitive functioning, self-related health, and life-satisfaction remained as strong predictors. Cancer was only associated with the mortality hazard when accounting for other co-morbidities. The survival estimates were mostly in anticipated directions and contained effect sizes within the expected range. Noteworthy, we found that some of the so-called “soft-markers” remained strong predictors, despite a control for other factors. For example, self-evaluation of health and ratings of life-satisfaction provide additional and valuable information. (shrink)

Naming or names (ming 名) is one of the key concepts in Daodejing (道德經). According to a popular understanding, names in Daodejing correspond to features (xing 形) of things; ordinary things have names, but Dao is featureless and nameless. What is missing, however, is atheory of the relationship between names and features explaining why ordinary things have names but Dao does not. In this paper, I develop a theory of names in Daodejing that explains how names relate to things and (...) their features. According to this theory, a name corresponds to a feature that is shared by a group of things, and names provide identity conditions for individuating ordinary things. Further, this theory implies that the various descriptions of Dao in Daodejing do not include names; therefore, talking about Dao while insisting that it is unnamable is not committed to any paradox. (shrink)

Punning on names was common in Old Comedy. Aristophanes punned on the name of Lamachus, who died at Syracuse. In the same play he made the famous joke, ‘some went to Kamarina, others to Gela, and some to Katagela’—‘an invention of the poet's from the fact that the men's officers laughed at them’.

Metamathematics and the Philosophical Tradition is the first work to explore in such historical depth the relationship between fundamental philosophical quandaries regarding self-reference and meta-mathematical notions of consistency and incompleteness. Using the insights of twentieth-century logicians from Gödel through Hilbert and their successors, this volume revisits the writings of Aristotle, the ancient skeptics, Anselm, and enlightenment and seventeenth and eighteenth century philosophers Leibniz, Berkeley, Hume, Pascal, Descartes, and Kant to identify ways in which these both encode and evade problems of (...) a priori definition and self-reference. The final chapters critique and extend more recent insights of late 20th-century logicians and quantum physicists, and offer new applications of the completeness theorem as a means of exploring "metatheoretical ascent" and the limitations of scientific certainty. Broadly syncretic in range, Metamathematics and the Philosophical Tradition addresses central and recurring problems within epistemology. The volume’s elegant, condensed writing style renders accessible its wealth of citations and allusions from varied traditions and in several languages. Its arguments will be of special interest to historians and philosophers of science and mathematics, particularly scholars of classical skepticism, the Enlightenment, Kant, ethics, and mathematical logic. (shrink)

本书以法学绪论的内容与任务的提出为基础,阐述了法的意义、法的渊源、法的分类、法的体系、法的制裁、法的适用,以及法与政治、经济的关系等理论。.

本书系统、扼要地介绍与评述了维也纳学派的理论原则和思想方法,还阐发了该学派对传统形而上学问题的基本观点。.

山西大学科学技术哲学研究中心资助国家教育部“十五”社科规划青年项目“当代西方分析哲学与解释学的融合”的研究成果.

Model-theoretic 1-types overa given first-order theory T may be construed as natural metalogical miniatures of G. W. Leibniz' ``complete individual notions'', ``substances'' or ``substantial forms''. This analogy prompts this essay's modal semantics for an essentiallyundecidable first-order theory T, in which one quantifies over such ``substances'' in a boolean universe V(C), where C is the completion of the Lindenbaum-algebra of T.More precisely, one can define recursively a set-theoretic translate of formulae νNϕ of formulae ν of a normal modal theory Tm based (...) on T, such that the counterpart `ξi' of a the modal variable `xi' of L(Tm) in this translation-scheme ranges over elements of V(C) that are 1-types of T with value 1 (sometimes called `definite' C-valued 1-types of T).The article's basic completeness-result (2.13) then establishes that ϕvarphi; is a theorem of Tm iff [[νN(ϕ) is aconsequenceof νN(Tm) for each extension N of T which is a subtheory of the canonical generic theory (ultrafilter) u]] = 1 – or equivalently, that Tm is consistent iff[[there is anextension N of T such that N is a subtheory of the canonical generic theory u, and νN(ϕ) for all ϕ in Tm]] > 0.The proof of thiscompleteness-result also shows that an N which provides a countermodel for a modally unprovable ϕ – or equivalently, a closed set in the Stone space St(T) in the sense of V(C) – is intertranslatable with an `accessibility'-relation of a closely related Kripke-semantics whose `worlds' are generic extensions of an initial universe V via C.This interrelation providesa fairly precise rationale for the semantics' recourse to C-valued structures, and exhibits a sense in which the boolean-valued context is sharp. (shrink)

A ground-motive for this study of some historical and metaphysical implications of the diagonal lemmas of Cantor and Gödel is Cantor's insightful remark to Dedekind in 1899 that the Inbegriff alles Denkbaren (aggregate of everything thinkable) might, like some class-theoretic entities, be inkonsistent. In the essay's opening sections, I trace some recent antecedents of Cantor's observation in logical writings of Bolzano and Dedekind (more remote counterparts of his language appear in the First Critique), then attempt to relativize the notion of (...) Inkonsistenz to self-sufficient theories T which interpret themselves. In effect, I argue that Gödel's diagonal lemma suggests a sense in which metatheoretic notions of proof, well-foundeness and satisfaction are object-theoretically inkonsistent. With respect to Cantor's Inbegriff, for example, the lemma yields that any object-theoretic reconstruction of thinkability generates an antidiagonal sentence , which one can paraphrase asSelf-referential application of the assertion that. (shrink)

In the the passage just quoted from theDialogues concerning Natural Religion, David Hume developed a thought-experiment that contravened his better-known views about chance expressed in hisTreatise and firstEnquiry.For among other consequences of the eternal-recurrence hypothesis Philo proposes in this passage, it may turn out that what the vulgar call cause is nothing but a secret and concealed chance.

COVID-19 often manifests with different outcomes in different patients, highlighting the complexity of the host-pathogen interactions involved in manifestations of the disease at the molecular and cellular levels. In this paper, we propose a set of postulates and a framework for systematically understanding complex molecular host-pathogen interaction networks. Specifically, we first propose four host-pathogen interaction (HPI) postulates as the basis for understanding molecular and cellular host-pathogen interactions and their relations to disease outcomes. These four postulates cover the evolutionary dispositions involved (...) in HPIs, the dynamic nature of HPI outcomes, roles that HPI components may occupy leading to such outcomes, and HPI checkpoints that are critical for specific disease outcomes. Based on these postulates, an HPI Postulate and Ontology (HPIPO) framework is proposed to apply interoperable ontologies to systematically model and represent various granular details and knowledge within the scope of the HPI postulates, in a way that will support AI-ready data standardization, sharing, integration, and analysis. As a demonstration, the HPI postulates and the HPIPO framework were applied to study COVID-19 with the Coronavirus Infectious Disease Ontology (CIDO), leading to a novel approach to rational design of drug/vaccine cocktails aimed at interrupting processes occurring at critical host-coronavirus interaction checkpoints. Furthermore, the host-coronavirus protein-protein interactions (PPIs) relevant to COVID-19 were predicted and evaluated based on prior knowledge of curated PPIs and domain-domain interactions, and how such studies can be further explored with the HPI postulates and the HPIPO framework is discussed. (shrink)

The Plight of Humanity in Paul In Paul and Palestinian Judaism, E. P. Sanders argues that, for Paul, humanity’s plight was not the condition that necessitated the solution of Jesus Christ. Instead, the solution was presented to Paul first on the Damascus road, and humanity’s plight was simply the logical corollary to the solution. This study will critically examine the particulars of Sanders’s argument— particularly with regard to Romans 7, Philippians 3, and Galatians 3—and offer some alternative exegetical analyses. This (...) essay will argue that, while the development of Paul’s thinking may indeed have run from solution to plight, the exposition of Paul’s thinking goes from plight to solution. The movement of Paul’s exposition may suggest that his conception of the plight of humanity was born out of his ideational milieu, which must have been fed, at least, by the Old Testament and evidenced, at least, by literature such as 4 Ezra. (shrink)

In the the passage just quoted from the Dialogues concerning Natural Religion, David Hume developed a thought-experiment that contravened his better-known views about "chance" expressed in his Treatise and first Enquiry. For among other consequences of the 'eternal-recurrence' hypothesis Philo proposes in this passage, it may turn out that what the vulgar call cause is nothing but a secret and concealed chance. (In this sentence, I have simply reversed "cause" and "chance" in a well-known passage from Hume's Treatise, p. 130). (...) In the first eight sections of this essay, I develop one topological and model-theoretic analogue of Hume's thought-experiment, in which 'most' ('A-generic') models M of a 'scientific' theory U are both 'eternally recurrent' and topologically random (in a sense which will be made precise), even though they are 'inductively' defined, via a step-by-step ('empirical'?) procedure that Hume might have been inclined to endorse. The last aspect of this model-theoretic thought-experiment also serves to distinguish it from simpler measure-theoretic prototypes that are known to follow from Kolmogorov's Zero-One Law (cf. the Introduction, 5.2, 6.1 and 6.7 below). In the last three sections, I will argue more informally (1) that the metamathematical thought-experiments just mentioned do have a genuine metaphysical relevance, and that this relevance is predominantly skeptical in its implications; (2) that such 'nonstandard' instances of semantic underdetermination and 'pathology' seem to be the metatheoretic rule rather than the exception; and therefore, (3) that metamathematical and metatheoretic 'malign-genius' arguments are quite coherent, contrary (e.g.) to assertions such as that of Putnam (1980), pp. 7-8. In the essay's conclusion, finally, I assimilate (2) and (3) to the familiar datum that 'simplicity', rather than 'pathology', has more often than not turned out to be an anomalous 'special case' in the historical development of scientific and mathematical ontology. (shrink)

Emergence is a notorious philosophical term of art. A variety of theorists have appropriated it for their purposes ever since George Henry Lewes gave it a philosophical sense in his 1875 Problems of Life and Mind. We might roughly characterize the shared meaning thus: emergent entities (properties or substances) ‘arise’ out of more fundamental entities and yet are ‘novel’ or ‘irreducible’ with respect to them. (For example, it is sometimes said that consciousness is an emergent property of the brain.) Each (...) of the quoted terms is slippery in its own right, and their specifications yield the varied notions of emergence that we discuss below. There has been renewed interest in emergence within discussions of the behavior of complex systems and debates over the reconcilability of mental causation, intentionality, or consciousness with physicalism. (shrink)

本书从创造和思想两方面,勾勒出西方一段艺术审美的演进过程,并说明这一演进的主导轨迹。内容包括古典时期的艺术与哲学、多元文化下的艺术审美、艺术哲学的体系建构以及艺术走向现代的分流四部分。.

The following framework of theses, roughly hewn, shapes contemporary discussion of the problem of mental causation: (1) Non-Identity of the Mental and the Physical Mental properties and states cannot be identified with specific physical properties and states. (2) Causal Closure (Completeness) of the Physical The objective probability of every physical event is fixed by prior physical events and laws alone. (This thesis is sometimes expressed in terms of explanation: In tracing the causal history of any physical event, one need not (...) advert to any non-physical events or laws. To the extent that there is any explanation available for a physical event, there is a complete explanation available couched entirely in physical vocabulary. We prefer the probability formulation, as it should be acceptable to any physicalist, though some reject the explanation formulation.) (3) Causal Exclusion There is at most one complete and wholly independent explanation for any given event or sequence of events. (shrink)

It has been contended that ostracism is prevalent in the workplace, and there has been increasing research interest in its potential effects. This paper extends the theoretical framework of workplace ostracism by linking it with affective commitment and intention to leave from the perspective of job embeddedness. Using time-lagged data from China, we apply job embeddedness theory to confirm that workplace ostracism decreases the cultivation of job embeddedness, which in turn undermines affective commitment and induces intention to leave. We also (...) find that intrinsic work motivation strengthens the detrimental effects of workplace ostracism on job embeddedness such that the negative relationship is stronger when intrinsic motivation is high rather than low. We further discuss the theoretical and practical implications of our findings and offer future research directions. (shrink)

This annotated critical edition is the first attempt to make Morris's 42,000-word verse sequence accessible to a modern audience.

Although most Asian states are signatories to UNCLOS, which offers options for dispute resolution by either voluntary or compulsory processes, in reality fewer than a dozen Asian states have taken advantage of such an approach. The decision to adopt third-party mechanisms comes under great scrutiny and deliberation, not least because of the entailing legal procedures and the politically sensitive nature of disputes. Vietnam claims the second-largest maritime area in the South China Sea dispute after China. A comparison of two recent (...) cases—the arbitration between the Philippines and China and the conciliation between Timor-Leste and Australia—highlights the importance of selecting between binding and nonbinding decisions and framing a complaint. In particular, any legal action under UNCLOS should specify China’s claims and actions in areas that encroach on Vietnam’s claimed exclusive economic zone (EEZ) and violate international law. (shrink)

The neural correlates of rapid eye movements (REMs) in sleep are extraordinarily robust; including REM-locked activation in the retrosplenial cortex, the supplementary eye field and areas overlapping cholinergic basal nucleus. The phenomenology of REMs speaks to the notion that perceptual experience in both sleep and wakefulness is a constructive process – in which we generate predictions of sensory inputs and then test those predictions through actively sampling the sensorium with eye movements. On this view, REMs during sleep may index an (...) internalized active sampling or ‘scanning’ of self-generated visual constructs that are not constrained by visual input. If this view is correct, it renders REMs an ideal probe to study consciousness as “an exclusively internal affair” (Metzinger 2009). In other words, REMs offer a probe of active inference – in the sense of predictive coding – when the brain is isolated from the sensorium in virtue of the natural blockade of sensory input during REM sleep. REMs are temporally precise events that enable powerful inferences based on timeseries analyses. As a natural, task-free probe, [REMs] could be used in non-compliant subjects, including infants and animals. In short, REM constitutes a promising probe to study the ontogenetic and phylogenetic development of consciousness and perhaps its abnormal development in schizophrenia and autism, which have been considered in terms of aberrant predictive coding. (shrink)

Rethinks the existing definitions of aesthetics and ethics and the relations between them.

本書首先介紹了斯賓諾莎的時代、生平和著作考釋，然後從形而上學、認識論和倫理學三方面對斯賓諾莎哲學體系進行分析和解釋，作者力圖從當代哲學認識成果出發，對斯賓諾莎哲學進行全面而系統的評價。書後並附有詳盡的 斯賓諾莎哲學參考文獻，以便讀者作更深一層的研究。.

本书选择了西方哲学主要学派论著中有代表性的文字片断,如:意志主义、新康德主义、直觉主义、分析哲学等。.

本书通过费希特的一生,表现了费希特在德意志民族文化意识发展过程中的地位,从而历史地重现了费希特的观念。.