BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

This landmark work provides a systematic introduction to systems of modal logic and stands as the first presentation of what have become central ideas in philosophy of language and metaphysics, from the "new theory of reference" and non-linguistic necessity and essentialism to "Kripke semantics.".

Appearing in English for the first time, Schelling’s 1842 lectures develop the idea that many philosophical concepts are born of religious-mythological notions.

Revonsuo proposed an intriguing and detailed evolutionary theory of dreams which stipulates that the biological function of dreaming is to simulate threatening events and to rehearse threat avoidance behaviors. The goal of the present study was to test this theory using a sample of 212 recurrent dreams that was scored using a slightly expanded version of the DreamThreat rating scale. Six of the eight hypotheses tested were supported. Among the positive findings, 66% of the recurrent dream reports contained one or (...) more threats, the threats tended to be dangerous and aimed at the dreamer, and when facing a threat, the dreamer tended to take defensive or evasive actions that were possible and reasonable. However, less than 15% of the recurrent dreams depicted realistic and probable situations critical for one’s physical survival or reproductive success and the dreamer rarely succeeded in fleeing the threat despite important and appropriate efforts. The findings thus provide mixed support for the threat simulation theory. (shrink)

In a study both ambitious and impressive in scope and breadth – spanning across a century of political thought and various intellectual traditions – Joshua L. Cherniss proposes a historical-normati...

With precision and profundity born of 30 years of devoted study, John Boyle offers an essential introduction to St. Thomas Aquinas on Scripture, shedding helpful light on the goals, methods, and commitments that animate the Angelic Doctor's engagement with the sacred page. Because the genius of St. Thomas's approach to the Bible lies not so much in its novelty but rather in the fidelity and clarity with which he recapitulates the riches of the preceding interpretive Tradition, this initiation into St. (...) Thomas's vision of Scripture is itself an orientation to the Church's vision of Scripture, from the Fathers through and beyond the Middle Ages. St. Thomas's embeddedness within the Church's Tradition and his own historical context is integral to his approach to Scripture, yet it sets him at some distance from modern readers, for whom his interpretive vision may seem perplexing or even impenetrable. In this Primer, Boyle first provides an acclimation to this medieval context through a survey and explanation of pertinent technical terminology used by St. Thomas and characteristic of the scholastic theology of the time. With an eye to the medieval practice of considering Scripture according to the fourfold division of causes, Boyle builds on this initial foundation by exploring in turn St. Thomas's accounts of the end or use of Scripture (final cause), its divine and human authorship (efficient cause), its order and division (material cause), and its literary styles or genres (formal cause). Drawing on writings from across St. Thomas's corpus, but especially his work On the Commendation and Division of Sacred Scripture and the prologues to his biblical commentaries, Boyle masterfully elucidates both the hermeneutical principles and deep wisdom of the Angelic Doctor's approach to Scripture, imparting invaluable guidance not only for reading and understanding St. Thomas and other great masters of the Tradition, but also-and ultimately-for understanding Scripture in light of this Tradition and reading it with greater benefit and joy. (shrink)

RésuméDans cet article, nous examinons le projet d'une critique de la raison historique mené par Wilhelm Dilthey et l'accusation d'historicisme portée contre lui par Heinrich Rickert. En comparant leurs tentatives respectives d'offrir un fondement philosophique aux sciences humaines, nous montrons que Dilthey et Rickert, en dépit de leurs divergences, convergent vers une réinterprétation productive de l'historicisme et conduisent à une reconfiguration de la relation entre philosophie et histoire. Cet article analyse trois implications théoriques et pratiques de l'historicisme : la mise (...) en valeur du particulier, le caractère historiquement situé du sujet connaissant et la primauté de la conscience historique. (shrink)

La vida de Siháb al-Din al-Suhrawardi es oscura. Datos aislados referentes a sus estudios, viajes y contactos se encuentran en breves noticias de los diccionarios biográ-ficos de los siglos xn y xm. Estas noticias permiten esbozar una biografía de al-Suhrawardi desde sus comienzos hasta la oposición de que fue objeto por parte de los Memas de Alepo y su trágica muerte, interpretada en el marco y el contexto de la ciu-dad. Todo este material de los diccionarios biográficos es sólo relativamente (...) fidedigno e incluso los textos contemporáneos incluyen datos erróneos. = Shiháb al-Din al-Suhrawardi's life is obscure. Some clues regarding his studies, travels and encounters are found in short biographical notices of the 12th and 13th centuries. These notices can provide the means to sketch al-Suhrawardi's biography: his early life, his coming to Aleppo, the mounting opposition of the Memas of Aleppo, and the final moments that led to his tragic death. The sociopolitical context of Aleppo provides a good framework for the interpretation of the data provided by the biographers. All these biographical works are, however, of relative reliability. Even the most contemporary texts are in fact not devoid of erroneous elements. (shrink)

"The chief business of twentieth-century philosophy” is “to reckon with twentieth-century history," claimed R. G. Collingwood. In this remarkable collection of essays, Frank Ankersmit demonstrates the prescience of that remark and goes a long way toward meeting its challenge. Responding to the work of Hayden White, Arthur Danto, and Hans-Georg Gadamer, he examines such issues as the difference between historical representation and artistic expression, the status of metaphor in historical description, and the relation of postmodernism to historicism. Ankersmit's fluent grasp (...) of European thought and his ability to incorporate concepts from literary theory, art history, the philosophy of science, and political thought into his analyses assure that this collection will interest readers throughout the humanities. (shrink)

Shihàb al-Dîn al-Suhrawardfs life is obscure. Some clues regarding his studies, travels and encounters are found in short biographical notices of the 12th and 13th centuries. These notices can provide the means to sketch al-Suhrawardfs biography: his early life, his coming to Aleppo, the mounting opposition of the ulemas of Aleppo, and the final moments that led to his tragic death. The ociopolitical context of Aleppo provides a good framework for the interpretation of the data provided by the biographers. All (...) these biographical works are, however, of relative reliability. Even the most contemporary texts are in fact not devoid of erroneous elements. (c) Consejo Superior de Investigaciones Científicas. (shrink)

Le contenu et la portée de l'ouvrage se déploient sur trois plans. Alliant outils d'histoire intellectuelle et approche philosophique, cet ouvrage jette tout d'abord un éclairage nouveau sur le problème de l'historicisme du point de vue de sa dimension pratique et de son rapport avec la philosophie politique au cours des années 1930 de même que durant la période de l'après-guerre. L'approche novatrice du livre conjugue épistémologie de l'histoire et théorie politique et permet de mettre en contexte la mobilisation politique (...) et idéologique du concept d'historicisme et ses corollaires, le relativisme et le nihilisme. La seconde partie du manuscrit traite plus directement d'une question centrale en philosophie politique, celle des fondements de la rationalité politique. À partir d'une réflexion sur la réception de la philosophie des valeurs de Max Weber, l'ouvrage aborde la question des possibilités et limites du jugement politique en temps de crise. Ensuite, cet ouvrage examine une dimension peu étudiée des oeuvres respectives de Leo Strauss et Raymond Aron. D'un point de vue historiographique, le livre montre que la reconstruction du dialogue amorcé entre les deux penseurs (à partir de sources d'archives incluant correspondances, transcriptions de séminaires et textes inédits) permet de jeter une lumière nouvelle sur la façon dont on peut conceptualiser l'utilité de l'histoire pour la philosophie politique. Finalement, dans le champ disciplinaire de la philosophie politique contemporaine, la figure de Raymond Aron est souvent peu considérée. L'une des visées de ce manuscrit est de montrer la pertinence de la philosophie aronienne du jugement et de la responsabilité politique. (shrink)

This paper will explore the gender discourse of contemporary Egyptian Islamists and argue that their gender discourse is not merely a religious and traditional discourse, but that this politico-religious Islamic ideology articulates a quite modern construct of gender equality. The gender discourse of a number of important Egyptian Islamists, al-Banna’, Qutb, al-Ghazali, al-Qaradawi and Ezzat will provide illustrations of these modern developments. Modern elements incorporated in today’s Islamist revivalist approaches create new understandings, neither purely traditional, nor purely modern, that are (...) ‘modern constructs’ that attempt to remain traditional, while integrating specifically modern components. The presence of these two seemingly opposing and contradictory elements may account for the present popularity that Islamist discourses enjoy in many Muslims countries. (shrink)

Dans cet article, nous cherchons à penser les enjeux philosophiques et politiques de l’application des méthodes interprétatives en histoire de la philosophie politique. À partir d’une étude de l’interprétation de Machiavel développée par Quentin Skinner, nous interrogeons la relation entre l’exposition théorique de sa méthodologie et son application effective à la pensée machiavélienne. Dans un premier temps, nous exposons les fondements du contextualisme skinnérien, en insistant d’une part sur sa critique des méthodes orthodoxes en histoire des idées, et d’autre part, (...) sur sa conception de l’intentionnalité d’un auteur du passé et sur la relation étroite entre théorie politique et vie politique qu’elle présuppose. Dans un second temps, nous analysons la mise en œuvre de cette méthode à partir du cas Machiavel, en illustrant les résultats féconds ainsi que les limites d’une telle théorie interprétative. Nous terminons par une analyse critique du projet politique qui sous-tend l’application de cette herméneutique. La thèse défendue est que la relation entre la dimension méthodologique et la dimension proprement politique de l’entreprise skinnérienne est marquée par une certaine tension. D’un côté, Skinner affirme que l’historien ne peut, et ne doit, retirer de leçons intemporelles de l’étude des auteurs du passé; la notion même de continuité entre les époques – l’idée d’une « grande Tradition » – serait un leurre. De l’autre, il critique la conception négative de la liberté mise de l’avant par des auteurs tels que John Rawls ou Isaiah Berlin, et propose une vision renouvelée du républicanisme qui puiserait à la source machiavélienne et permettrait de réconcilier liberté individuelle et participation citoyenne. En explorant tour à tour ces deux volets et l’articulation parfois problématique entre les deux, nous interrogeons la nature de cette équivoque entre les visées méthodologiques de Skinner en tant qu’historien des idées et son propos en tant que théoricien politique. (shrink)

Avicenna (d. 1037) bequeathed the Arabic philosophical tradition with an aporia : self-knowledge is conceived, at times, in terms of intellection, at other times, in terms of apperception. In his Book of Discussions and Book of Notes, Avicenna has lengthy discussions on apperception, defined as a direct ontological mode of knowledge. Heir to this tradition, Shihāb al-Dīn al-Suhrawardī (d. 1191) moved away from the first conception of self-knowledge as intellection to adopt the second conception of an apperception of the self (...) as a direct, intuitive and "presential (hcombining dot belowudcombining dot belowūrī)" perception, and which he defended with four types of arguments. (shrink)

Mullā Ṣadrā and Eschatology: Evolution of Being By al-KutubiEiyad S, vii + 151 pp. Price HB £85.00. EAN 978–1138794160.

Ethics for Enemies comprises three original philosophical essays on torture, terrorism, and war. F. M. Kamm deploys ethical theory in her challenging new treatments of these most controversial practical issues. First she considers the nature of torture and the various occasions on which it could occur, in order to determine why it might be wrong to torture a wrongdoer held captive, even if this were necessary to save his victims. In the second essay she considers what makes terrorism wrong--whether it (...) is the intention to harm civilians, rather than harm to them being 'collateral damage,' or something else--and whether terrorism is always wrong. The third essay discusses whether having a right reason, in the sense of a right intention, is necessary in order for a war to be just. Kamm then examines ways in which the harms of war can be proportional to the achievement of the just cause and other goods that war can bring about, so as to make the declaration of war permissible. (shrink)

This is an English translation of Schelling's Ideas for a Philosophy of Nature (first published in 1797 and revised in 1803), one of the most significant works in the German tradition of philosophy of nature and early nineteenth-century philosophy of science. It stands in opposition to the Newtonian picture of matter as constituted by inert, impenetrable particles, and argues instead for matter as an equilibrium of active forces that engage in dynamic polar opposition to one another. In the revisions of (...) 1803 Schelling incorporated this dialectical view into a neo-Platonic conception of an original unity divided upon itself. The text is of more than simply historical interest: its daring and original vision of nature, philosophy, and empirical science will prove absorbing reading for all philosophers concerned with post-Kantian German idealism, for scholars of German Romanticism, and for historians of science. (shrink)

How many words—and which ones—are sufficient to define all other words? When dictionaries are analyzed as directed graphs with links from defining words to defined words, they reveal a latent structure. Recursively removing all words that are reachable by definition but that do not define any further words reduces the dictionary to a Kernel of about 10% of its size. This is still not the smallest number of words that can define all the rest. About 75% of the Kernel turns (...) out to be its Core, a “Strongly Connected Subset” of words with a definitional path to and from any pair of its words and no word's definition depending on a word outside the set. But the Core cannot define all the rest of the dictionary. The 25% of the Kernel surrounding the Core consists of small strongly connected subsets of words: the Satellites. The size of the smallest set of words that can define all the rest—the graph's “minimum feedback vertex set” or MinSet—is about 1% of the dictionary, about 15% of the Kernel, and part-Core/part-Satellite. But every dictionary has a huge number of MinSets. The Core words are learned earlier, more frequent, and less concrete than the Satellites, which are in turn learned earlier, more frequent, but more concrete than the rest of the Dictionary. In principle, only one MinSet's words would need to be grounded through the sensorimotor capacity to recognize and categorize their referents. In a dual-code sensorimotor/symbolic model of the mental lexicon, the symbolic code could do all the rest through recombinatory definition. (shrink)

The limited aim here is to explain what John Dewey might say about the formulation of the grue example. Nelson Goodman’s problem of distinguishing good and bad inductive inferences is an important one, but the grue example misconstrues this complex problem for certain technical reasons, due to ambiguities that contemporary logical theory has not yet come to terms with. Goodman’s problem is a problem for the theory of induction and thus for logical theory in general. Behind the whole discussion of (...) these issues over the last several decades is a certain view of logic hammered out by Russell, Carnap, Tarski, Quine, and many others. Goodman’s nominalism hinges in essential ways on a certain view of formal logic with an extensional quantification theory at its core. This raises many issues, but the one issue most germane here is the conception of predicates ensconced in this view of logic. (shrink)

The essays in this collection address different aspects of Dewey's philosophy of logic, from his work at the beginning of the twentieth century to the culmination of his logical thought in the 1938 volume, Logic: The Theory of Inquiry.