The epistemic stances of both Whitehead and the Book of Changes are founded on the assumption that process is reality; there are important resonances with respect to perception, meaning and significance. Such a process-oriented approach is productive for developing non-representational and non-dualistic theories in the fields of epistemology, philosophy of language and philosophy of mind. An exploration of these resonances will further provide an appropriate foundation for dialogue between the philosophy of the Book of Changes and that of contemporary Euro-American (...) philosophy. The important differences between the Book of Changes and Whiteheadian philosophy will also become apparent. (shrink)

Physicians play a substantial role in facilitating communication regarding life-supporting treatment decision-making including do-not-resuscitate in the intensive care units. Physician-related fact...

Recent studies support a model in which the progeny of SOX9+ epithelial progenitors at the distal tip of lung branches undergo cell allocation and differentiation sequentially along the distal‐to‐proximal axis. Concomitant with the elongation and ramification of lung branches, the descendants of the distal SOX9+ progenitors are distributed proximally, express SOX2, and differentiate into cell types in the conducting airways. Amid subsequent sacculation, the distal SOX9+ progenitors generate alveolar epithelial cells to form alveoli. Sequential cell allocation and differentiation are integrated (...) with the branching process to generate a functional branching organ. This review focuses on the roles of SOX9+ cells as precursors for new branches, as the source of various cell types in the conducting airways, and as progenitors of the alveolar epithelium. All of these processes are controlled by multiple signaling pathways. Many mouse mutants with defective lung branching contain underlying defects in one or more steps of cell allocation and differentiation of SOX9+ progenitors. This model provides a framework to understand the molecular basis of lung phenotypes and to elucidate the molecular mechanisms of lung patterning. It builds a foundation on which comparing and contrasting the mechanisms employed by different branching organs in diverse species can be made. (shrink)

With a previous paper (Niu & Wang, 1995), a general, hypothetical outline of the mechanism of carcinogenesis was proposed. With reference to the fact of starvation-induced hypermutation in micro-organisms, we propose that the hypoxia commonly seen in the cells at the centre of solid tumours might also result in hypermutation, and then p53-dependent programmed cell death. Like the apparently adaptive mutations in micro-organisms, only those genes (e.g. p53) that enable the cells to escape from apoptosis may be selected.

Division of labour is a marked feature of multicellular organisms. Margulis proposed that the ancestors of metazoans had only one microtubule organizing center (MTOC), so they could not move and divide simultaneously. Selection for simultaneous movement and cell division had driven the division of labour between cells. However, no evidence or explanation for this assumption was provided. Why could the unicellular ancetors not have multiple MTOCs? The gain and loss of three possible strategies are discussed. It was found that the (...) advantage of one or two MTOC per cell is environment-dependent. Unicellular organisms with only one MTOC per cell are favored only in resource-limited environments without strong predatory pressure. If division of labour occurring in a bicellular organism just makes simultaneous movement and cell division possible, the possibility of its fixation by natural selection is very low because a somatic cell performing the function of an MTOC is obviously wasting resources. Evolutionary biologists should search for other selective forces for division of labour in cells. (shrink)

Modern education attaches great importance to interdisciplinary skills, among which computational thinking is a core element, and heralds a new era. IT application has shaped education in the 21st century. Computational thinking has provided further impetus for building an all-encompassing social network and fostering a DIY culture enabled by digital technologies. One empirical study used four apps to test children's development in computational thinking and fluency. The article will help students overcome their fears of coding. Peer reviews provide students with (...) an opportunity to learn from each other and become more motivated. These reviews also serve as feedback for teachers to evaluate students' performance. Experimental design is used in this study, and a peer review system is implemented. Freshmen attending a programming class in a university are used as samples. At the class, students write computer programs with f-Chart, which provides a graphical user interface for students to learn programming logic and design. Zuvio, a cloud-based interactive response system, is used to conduct the peer reviews. The data of this study are analyzed through R. The results show not only an improvement in students' learning performance but also a gap between students' peer review scores and teachers' evaluation scores. Learning feedback and evaluation is crucial to transform education between students and teachers into a sustainable cycle system. (shrink)

Background Individual physicians and physician-associated factors may influence patients’/surrogates’ autonomous decision-making, thus influencing the practice of do-not-resuscitate orders. The objective of this study was to examine the influence of individual attending physicians on signing a DNR order. Methods This study was conducted in closed model, surgical intensive care units in a university-affiliated teaching hospital located in Northern Taiwan. The medical records of patients, admitted to the surgical intensive care units for the first time between June 1, 2011 and December 31, (...) 2013 were reviewed and data collected. We used Kaplan–Meier survival curves with log-rank test and multivariate Cox proportional hazards models to compare the time from surgical intensive care unit admission to do-not-resuscitate orders written for patients for each individual physician. The outcome variable was the time from surgical ICU admission to signing a DNR order. Results We found that each individual attending physician’s likelihood of signing do-not-resuscitate orders for their patients was significantly different from each other. Some attending physicians were more likely to write do-not-resuscitate orders for their patients, and other attending physicians were less likely to do so. Conclusion Our study reported that individual attending physicians had influence on patients’/surrogates’ do-not-resuscitate decision-making. Future studies may be focused on examining the reasons associated with the difference of each individual physician in the likelihood of signing a do-not-resuscitate order. (shrink)

Inspired by the application of CycleGAN networks to the image style conversion problem Zhu et al., this paper proposes an end-to-end network, DefogNet, for solving the single-image dehazing problem, treating the image dehazing problem as a style conversion problem from a fogged image to a nonfogged image, without the need to estimate a priori information from an atmospheric scattering model. DefogNet improves on CycleGAN by adding a cross-layer connection structure in the generator to enhance the network’s multiscale feature extraction capability. (...) The loss function was redesigned to add detail perception loss and color perception loss to improve the quality of texture information recovery and produce better fog-free images. In this paper, the novel Defog-SN algorithm is presented. This algorithm adds a spectral normalization layer to the discriminator’s convolution layer to make the discriminant network conform to a 1-Lipschitz continuum and further improve the model’s stability. In this study, the experimental process is completed based on the O-HAZE, I-HAZE, and RESIDE datasets. The dehazing results show that the method outperforms traditional methods in terms of PSNR and SSIM on synthetic datasets and Avegrad and Entropy on naturalistic images. (shrink)

Obtaining adequate informed consent from trauma patients is challenging and time-consuming. Healthcare providers must communicate complicated medical information to enable patients to make informed decisions. This study aimed to explore the challenges of obtaining valid consent and methods of improving the quality of the informed consent process for surgical procedures in trauma patients. We conducted a systematic review of relevant English-language full-text original articles retrieved from PubMed that had experimental or observational study design and involved adult trauma patients. Studies involving (...) informed consent in clinical or research trials were excluded. Titles and abstracts of searched articles were reviewed and relevant data were extracted with a structured form. Results were synthesized with a narrative approach. A total of 2044 articles were identified in the initial search. Only eight studies were included in the review for narrative synthesis. Six studies involved orthopedic surgeries, one involved nasal bone surgeries, and one involved trauma-related limb debridement. Only one study was conducted in an emergency department. Information recall was poor for trauma patients. Risk recall and comprehension were greater when written or video information was provided than when information was provided only verbally. Patient satisfaction was also greater when both written and verbal information were provided than when verbal information alone was provided; patients who received video information were more satisfied than patients who received written or verbal information. Many articles have been published on the subject of informed consent, but very few of these have focused on trauma patients. More empirical evidence is needed to support the success of informed consent for trauma patients in the emergency department, especially within the necessarily very limited time frame. To improve the informed consent process for trauma patients, developing a structured and standardized informed consent process may be necessary and achievable; its effectiveness would require evaluation. Adequately educating and training healthcare providers to deliver structured, comprehensive information to trauma patients is crucial. Institutions should give top priority to ensuring patient-centered health care and improved quality of care for trauma patients. (shrink)

Reorienting the Political examines the reception of two controversial German philosophers, Carl Schmitt and Leo Strauss, in the Chinese-speaking world. This volume explores the powerful resonance of both thinkers in Chinese political thought from a cross-cultural and interdisciplinary perspective.

Background Adherence to ethical guidelines and regulations and protecting and respecting the dignity and autonomy of participants by obtaining a valid informed consent form (ICF) prior to participation in research are crucial; The subjects did not add signatures next to the corrections made to signatures or dates on the ICF, Multiple signatures in other fields, ICF missing/missing signature, Incorrect ICF version Signed after modification, Correction tape used to correct signature, Impersonated signature, Non-research-member signature, however, ICFs are often not properly completed, (...) which must be addressed. This study analyzed ICF signing errors and implemented measures to reduce or prevent these errors. Methods We used the plan–do–check–act (PDCA) cycle to help improve the correctness and validity of ICF signing. Results Interim and final reports from January 2016 to February 2020 including 363 ICFs were studied. The total proportion of correct ICF signatures (200, 83.3%) following the PDCA intervention was significantly higher than that before the intervention (P < 0.05). Analysis of the types of signing error demonstrated that signature errors were significantly reduced after the intervention, particularly for subjects did not add signatures next to the corrections made to signatures or dates on the ICF (16, 6.7%) and impersonated signature (0; P < 0.05). Conclusions The proportions of other error types—multiple signatures in other fields, missing or unsigned ICF, incorrect signature order, incorrect ICF version, use of correction tape to correct signature, and non-medical profession members signing the ICF—did not differ significantly. (shrink)

本书内容包括:STS与东亚国家的工业化、城市化和国际化;STS与中国东北老工业基地改造和振兴的战略与对策;科学技术与文化;文化背景中的创新:科技创新、制度创新、管理创新和体制创新等问题;其他STS研究 的基本理论与现实问题。.

Resumo: Chuang Tzu (《庄子》), como um cânone tradicional chinês, foi traduzido para o inglês por mais de 100 anos, desde 1881, conquistando com sucesso um nicho no reino da literatura mundial, que se tornou um evento cultural devastador na academia de sinologia ultramarina e literatura mundial. Segundo as estatísticas, o livro foi traduzido em 12 traduções completas, 50 traduções selecionadas e duas adaptações. No processo de metamorfose da “tradução completa - tradução profunda - retradução diversificada”, passou por quatro fases, (...) nomeadamente fases religiosas, literárias, filosóficas e reinterpretações diversificadas. Assim, na perspectiva da visão de Damrosch a respeito da literatura mundial, o artigo resume as características de diferentes estágios, com base em diferentes contextos espaço-temporais. À luz da forma tradutória, dos resultados tradutórios e do modo de leitura tradutória, especifica-se o caminho pelo qual Chuang Tzu entrou no campo da literatura mundial, para apreender o mecanismo operacional de promoção da literatura nacional à literatura mundial, que se dedica ao esclarecimento para o trabalho prático de tradução da introdução da literatura chinesa no exterior. Enquanto isso, revisando a história das traduções inglesas de Chuang Tzu, o artigo resume as deficiências das atuais atividades de tradução e pesquisa, com a tentativa de fornecer sugestões construtivas, bem como apontar a direção para o desenvolvimento futuro de estudos de Chuang Tzu no exterior. (shrink)

本书选录了《第六届马克思哲学论坛》的论文36篇,按专题分为马克思主义政治哲学及其当代意义、西方政治哲学的传统及其启示、当代政治哲学的基本问题与理论视域三个部分。.

A new translation of one of the great koan collections--by the premier translator of the Chinese classics--that reveals it to be a literary and philosophical masterwork beyond its association with Chan/Zen. Zen is famous for its koans, those seemingly confounding statements, questions, or stories that masters use to gauge their students' practice. Here, the lauded modern master of Chinese poetry translation asks us to reimagine one of the greatest of the koan collections in a new way: as a classic of (...) Chinese philosophical literature in the tradition of the Tao Te Ching or the Chuang Tzu. He presents the No-Gate Gateway (variously also familiar to readers as the Mumonkan, Wu-men Kuan, Gateless Gate, or Gateless Barrier), in a "bare bones" version, without the usual additional commentary, not intended to be studied in the usual case-by-case method, but to be read as a complete work in itself, one that leads the reader carefully on a path to the discovery of the deep nature of reality--an unconventional way of reading it that can be truly revelatory. (shrink)

Harry Frankfurt had insightfully pointed out that an agent acts freely when he acts in accord with the mental states with which he identifies. The concept of identification rightly captures the ownership condition (something being one’s really own), which plays a significant role in the issues of freedom and moral responsibility. For Frankfurt, identification consists of one’s forming second-order volitions, endorsing first-order desires, and issuing in his actions wholeheartedly. An agent not only wants to φ but also fully embraces his (...) desire to φ (and φ). Frankfurt’s official theory above encounters some serious problems, especially since it is believed that his concept of wholehearted identification is too strong to be necessary for freedom. In this paper, I propose that we can uncouple identification from wholeheartedness and thus get two different senses of identification: weak identification and strong identification. Then, I argue that this distinction does a better job than Frankfurt’s official theory. On the one hand, weak identification is enough for ownership and freedom and thus more promising than strong identification; on the other hand, this distinction has an attractive implication that it fits well with our intuition about the degree of freedom and responsibility. (shrink)

First-ever comprehensive introduction to the major new subject of quantum computing and quantum information.

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:A Companion to Angus C. Graham's Chuang Tzu: The Inner ChaptersSteve CoutinhoA Companion to Angus C. Graham's Chuang Tzu: The Inner Chapters. By Harold D. Roth. Monographs of the Society for Asian and Comparative Philosophy, 20. Honolulu: University of Hawai'i Press, 2003. Pp. 243. Paper $18.00.Scholars of Chuang Tzu—and "children of Angus"—will enthusiastically welcome Harold Roth's A Companion to Angus C Graham's Chuang Tzu: (...) The Inner Chapters, a collection of A. C. Graham's scholarly studies of the Chuang Tzu. Thanks to Roth's concerted efforts, Graham's scholarship on the Chuang Tzu has now been made readily available in a single volume. A. C. Graham was one of the most distinguished Western scholars of classical Chinese philosophy and one of the leading interpreters of the philosophy of Chuang Tzu. His pioneering research—textual, linguistic, and philosophical—on the Chuang Tzu and on its philosophical predecessor, the Later Mohist Canon, have laid the scholarly groundwork for further explorations of this philosophical and literary masterpiece.This collection includes: Graham's "Textual Notes to Chuang Tzu: The Inner Chapters," first published as a scholarly monograph in 1982 as a supplement to the Bulletin of the School of Oriental and African Studies, under the title "Chuang-tzu: Textual Notes to a Partial Translation"; "How Much of Chuang Tzu Did Chuang Tzu Write?" which first appeared in 1976 in the Journal of the American Academy of Religion; [End Page 126] "Chuang Tzu's Essay on Seeing Things As Equal," written in 1968 for the Bellagio Conference on Taoist Studies and first published in a volume of History of Religions; "Two Notes on the Translation of Taoist Classics," which first appeared in 1991 in Interpreting Culture Through Translation: A Festschrift for D. C. Lau; and "Taoist Spontaneity and the Dichotomy of 'Is' and 'Ought,'" first published in 1983 in Victor Mair's Experimental Essays on the Chuang Tzu. The Companion ends with a Colophon by Harold Roth, "An Appraisal of Angus Graham's Textual scholarship on the Chuang Tzu."Chapter 1 reproduces Graham's textual notes on his translation of the Chuang tzu. Graham had written his "Textual Notes to Chuang Tzu: The Inner Chapters" while working on his translation of the Inner Chapters, and he had hoped to include them in the final version of Chuang Tzu: The Inner Chapters. Since this was not possible, Graham had them published instead by SOAS as a supplement to their Bulletin. Roth begins the Companion with a painstakingly reproduced computer-input version of Graham's original typewritten manuscript, which he also reorganized so that it corresponds to the (somewhat idiosyncratic) order and structure of Graham's translation. For ease of cross-reference, page numbers are provided to both Graham's translation and the Harvard Concordance (Chuang-tzu yin-te), the source text with which Graham worked.Chapter 2 is Graham's study, "How Much of Chuang Tzu Did Chuang Tzu Write?" This was written in large part as a response to Fu Ssu-nien's extraordinary and controversial claim that chapter 2, "Qi Wu Lun," is not the work of Chuang Tzu but of Shen Tao. In this paper Graham also attempts to identify how much of what he calls the "ragbag" chapters could have come from the same author as the Inner Chapters. The technique he uses is a straightforward tabulation of occurrences of characteristic usages and expressions in the various chapters, followed by a set of detailed comments. He compares carefully chosen idioms, grammatical particles and patterns, philosophical terms, and references to persons and themes. Comparisons are made specifically between the Inner Chapters, the "ragbag" chapters together with chapter 32, and the rest of the book.This is followed by a detailed justification of his "reconstruction" of what he believes to be the original introductory paragraph to chapter 3, "Yang Sheng Zhu." The next two sections put forward reasons for dividing the "Anarchist" chapters (8 to 11a, and 28 to 31) into two sections, the former group (8 to 11a) attributed to a person he calls the "Primitivist," the latter (28 to 31), following the argumentation of Kuan Feng, attributed to the... (shrink)

Despite its apparent complexity, our world seems to be governed by simple laws of physics. This volume provides a philosophical introduction to such laws. I explain how they are connected to some of the central issues in philosophy, such as ontology, possibility, explanation, induction, counterfactuals, time, determinism, and fundamentality. I suggest that laws are fundamental facts that govern the world by constraining its physical possibilities. I examine three hallmarks of laws--simplicity, exactness, and objectivity--and discuss whether and how they may be (...) associated with laws of physics. (shrink)

What is the future of Philosophy of education? Or as many of scholars and thinkers in this final ‘future-focused’ collective piece from the philosophy of education in a new key Series put it, what are the futures—plural and multiple—of the intersections of ‘philosophy’ and ‘education?’ What is ‘Philosophy’; and what is ‘Education’, and what role may ‘enquiry’ play? Is the future of education and philosophy embracing—or at least taking seriously—and thinking with Indigenous ethicoontoepistemologies? And, perhaps most importantly, what is that (...) ‘Future’? These debates have been located in the work of diverse scholars: from the West, from Global South, from indigenous thinkers. In this collective piece, we purposefully juxtapose diverse takes on the future of these intersections. We have given up the urge to organise, place together, separate with subheadings or connect the paragraphs that follow. Instead, we let these philosophers of education and thinkers who use philosophical texts and ideas to sit together in one long read as potentially ‘strange and unusual bedfellows’. This text urges us to understand how these scholars and thinkers perceive our educational philosophical futures, and how the work and thinking they have done on thinking about what the future of that new key in philosophy of education may look like is embedded in a much deeper and richer literature, and personal experience. (shrink)

This book reprints an ancient Chinese work from the late Warring States period (3rd century BC) that contains stories and anecdotes exemplifying the carefree nature of the ideal Taoist sage. Chuang Tzu's philosophy represents the main current of Taoist teachings, and his text is widely regarded as both deeply insightful and a great achievement in the Chinese poetical essay form. The version presented was translated by Feng Yu-lan, the famous Chinese philosopher, who puts more emphasis on Chuang Tzu's (...) philosophy than do previous attempts. William James once said that every great philosopher has a personal vision. When one has grasped that vision, the whole system can be easily understood. And Crocé once said that the greater a philosophical system is, the simpler the central idea. Although the present translation is limited to the first seven chapters of Chuang Tzu's writings, it accurately conveys his main vision and ideas. (shrink)

Our paper reports and discusses issues relating to subjective wellbeing in selected countries in ASEAN (The Association of Southeast Asian Nations), a regional organization that coordinates and promotes the economic, social and cultural interests of member countries in Southeast Asia. Comparisons will be made across the five founding members of ASEAN, namely Indonesia, Malaysia, Philippines, Singapore and Thailand using data from the 2004, 2006 and 2007 AsiaBarometer Surveys. The indicators of subjective wellbeing used are perceptions of happiness, enjoyment, and achievement. (...) We also examined the impact of selected demographic and non-demographic variables on these indicators. (shrink)