The process of chromatin diminution in Parascaris and Ascaris is a developmentally controlled genome rearrangement, which results in quantitative and qualitative differences in DNA content between germ line and somatic cells. Chromatin diminution involves chromosomal breakage, new telomere formation and DNA degradation. The programmed elimination of chromatin in presomatic cells might serve as an alternative way of gene regulation. We put forward a new hypothesis of how an ancient partial genome duplication and chromatin diminution may have served to maintain the (...) genetic balance in somatic cells and simultaneously endowed the germ line cells with a selective advantage. (shrink)

The implicit activities of the living body in sports (such as heart rate, involuntary gestures, stress, reflex, emotional regulation and interaction expressions) emerge in the consciousness of the lived body without our voluntary control. We demonstrate physiological emersion, and how, including in dramaturgical perception, physiological flows and processes collide with the image of a whole body. In this paper, we introduce corporeal non-property as the missing (?) link between phenomenology and neuroscience, renewed by research on the cerebral unconscious and the (...) perception of their lived body. Rather than mindfulness, physical activity obliges the subject to learn the unconscious and his motor skills from his living body: a new psychoanalysis of sport is thus established by studying what emerges from the activity of the living body up to the level of the conscious description of motor action. In this paper, we explain why that awareness occurs, and why it matters for the understanding of unconscious activity of the athlete’s living body. This is potentially interesting, although it needs, as a theory, to overcome the obvious reliance of the body on unconscious or habitual/automated physiological processes. But the incorporation of body techniques forms a habitus. (shrink)

New concepts may prove necessary to profit from the avalanche of sequence data on the genome, transcriptome, proteome and interactome and to relate this information to cell physiology. Here, we focus on the concept of large activity-based structures, or hyperstructures, in which a variety of types of molecules are brought together to perform a function. We review the evidence for the existence of hyperstructures responsible for the initiation of DNA replication, the sequestration of newly replicated origins of replication, cell division (...) and for metabolism. The processes responsible for hyperstructure formation include changes in enzyme affinities due to metabolite-induction, lipid-protein affinities, elevated local concentrations of proteins and their binding sites on DNA and RNA, and transertion. Experimental techniques exist that can be used to study hyperstructures and we review some of the ones less familiar to biologists. Finally, we speculate on how a variety of in silico approaches involving cellular automata and multi-agent systems could be combined to develop new concepts in the form of an Integrated cell (I-cell) which would undergo selection for growth and survival in a world of artificial microbiology. (shrink)

Although complex hallucinations are extremely vivid, painful symptoms in schizophrenia, little is known about the underlying mechanisms of multisensory integration in such a phenomenon. We investigated the neural basis of these altered states of consciousness in a patient with schizophrenia, by combining state of the art neuroscientific exploratory methods like functional MRI, diffusion tensor imaging, cortical thickness analysis, electrical source reconstruction and trans-cranial magnetic stimulation. The results shed light on the functional architecture of the hallucinatory processes, in which unimodal information (...) from different modalities is strongly functionally connected to higher-order integrative areas. (shrink)

This essay engages with Bernard Stiegler’s discussion with Martin Heidegger in The ordeal of Truth, published in Foundations of Science 2020. It appreciates Stiegler’s progressive reading of Heidegger’s work but critically reflects on several elements in his work. A first element is the methodological aspect of Heidegger’s being historical thinking, which is missed by Stiegler and confirms the indifference towards philosophical method that can be found in the work of many contemporary philosophers. A second element concerns Heidegger’s and Stiegler’s (...) remaining humanism and the necessity to move beyond humanism and post-humanism in the era of global warming. A third element of reflection concerns Stiegler’s idea of the obligation of making our being-in-default come true, which shows a hidden metaphysical orientation in his work. (shrink)

Vincent Jullien, dont on connait les travaux remarquables sur les mathématiques au XVIIe siècle, et en particulier chez Descartes, offre dans cet ouvrage ses réflexions sur une histoire des sciences telle qu’il la pratique depuis plusieurs décennies. L’ouvrage est divisé en trois parties. La première est une défense de la méthode de l’épistémologie historique, en tant qu’elle s’oppose à une épistémologie analytique ou logique. La seconde s’emploie à montrer que, quelle que soit l’intime conne...

Discussion on God's knowledge, awareness of God with people though are different, but still closely related. This article talks about God's knowledge, although knowledge of God and the people, but not for the medieval Shengboerna the so-called "secular knowledge" and "God of knowledge" distinction; this will only be God's own knowledge or wisdom, philosophical discussion. First, the paper will compare the start, mainly related to the so-called Fozhi Buddhism and Western philosophers such as Aristotle,圣多瑪斯, Hegel and others about God, know (...) God, absolute spirit of the discussion, especially圣多瑪斯discussion on knowledge of God, compare, and summarize them are focused on comprehensive and complete self-conscious, and of all things and the universal and the individual's knowledge. Then, this paper will further discuss whether it contains the narrative of God to know the ingredients, that is God for individuals and groups in the body of the story or may occur, actual and imagined the story of building awareness. In short, my book can only be regarded as restricted view up to see. Both for Glimpse, then it is limited, should be able to break the world's big pipe to significantly; both for the discussion, it should be deconstructed in order to display the infinite Creator. The discussion of "Scientia Dei " is very much related to, though still different from, the question "Quomodo Deus a nobis cognoscatur ." This paper deals with Scientia Dei, not in the sense it is distinguished from Scientia Mundi by St Bernard of Clairvaux, but in the sense it is related to all philosophical discourses on the wisdom of God Himself. The first step of this paper is a comparative study with "Buddha's Wisdom" taught by some major Mahayana Buddhist Schools, and the ideas of God, God's Knowledge and Absolute Spirit in Aristotle, St. Thomas and Hegel, in particular St. Thomas' discussion of "Scientia Dei." The result of this comparison is their common emphasis on God's total and complete transparent self-understanding, and His universal and concrete knowledge of all things. After this, we will move on to discuss the narrative component of Scientia Dei, to see whether in God's knowledge there is a place for the historical and imaginative stories of all social groups and individuals, of their inexhaustible possibilities, developments and constructions, both descriptive and imaginative. Anyhow, this essay is limited to a comparative and discursive study, without any ground in the author's religious experience with God's knowledge. Therefore it should be deconstructed once it is pronounced, erased once it is written. (shrink)

La décade de Cerisy Gilbert Simondon ou l'invention du futur a rassemblé des philosophes tels que Jean-Hugues Barthélémy, Andrew Feenberg ou Bernard Stiegler, des chercheurs venus d'autres disciplines, tels qu'Armand Hatchuel, Gilles Cohen-Tannoudji ou Thierry Gaudin, et toute une génération de jeunes chercheurs. Il en résulte un livre foisonnant où l'astrophysique côtoie la psychothérapie, où l'architecture dialogue avec l'informatique, et où tous ces savoirs tendent vers une communication encyclopédique. Il débute avec les "transductions politiques de Simondon" pour penser la (...) relation entre les évolutions technologiques et les normativités sociales. Puis, il aborde "la techno-esthétique" et le design, frayant la voie à une esthétique interne à la réalité technique qui ne repose plus sur la contemplation mais sur la participation à la technicité. Avec la "culture technologique", il est question des techniques à l'échelle du nanomètre et des instruments astronomiques spatiaux, qui imposent à la Culture d'intégrer les schèmes de la communication entre échelles. Le quatrième volet, consacré au "préindividuel quantique", propose une ré-interprétation de la mécanique quantique fondée sur les notions de préindividualité, de potentialité et de phases. "L'information et les réseaux", leurs enjeux, sont ensuite étudiés en relation avec l'informatique et les TIC. Ces technologies conditionnant aussi l'individuation psychique et collective, l'enquête se prolonge en direction du "sens du transindividuel". Enfin, ce cycle de réflexions s'achève sur "une philosophie en devenir" et les interventions esquissant des lignes d'évolution possibles pour la philosophie de Simondon. Premier jalon dans l'internationalisation des études simondoniennes, cet ouvrage propose une perspective résolument orientée vers l'invention du futur."--Page 4 of cover. (shrink)

The paper centres on a particular pattern of argument in Bernard Bosanquet aesthetic writings. This pattern is one which has roots in a more general Idealist response to Kant's formulation of the problem of aesthetic judgment. In other words, it has roots in thinkers such as Schiller, Schelling and Hegel. The core of the pattern of argument concentrates on the relation, in both artistic production and contemplation, between reason and sensuousness and form and content. The paper tries to show (...) how Bosanquet, in formulating his aesthetic theory, fashions his argument into what I call a 'social aesthetic'. He is helped in this process of formulating a 'social aesthetic' by subtly linking his Hegelian-based arguments with the ideas of both William Morris and John Ruskin. Throughout the paper the various arguments revolve therefore around the central relation of reason and sensuousness and form and content. (shrink)

En sciences biomédicales, diverses techniques d’imagerie permettent l’exploration d’organismes vivants, aussi bien pour le diagnostic que pour l’expérimentation. En se penchant sur l’une d’entre elles, la scintigraphie, on montre que l’utilisation d’un instrument complexe revêt toujours un caractère expérimental, même lorsque l’on entend l’utiliser à des fins d’observation diagnostique. La liste des tests qui sont à entreprendre sur la machine à diverses échelles de temps démontre que les chercheurs ne peuvent jamais l’utiliser en lui accordant leur confiance de manière inconditionnelle. (...) L’observation est encadrée par l’expérimentation, démontrant aussi l’actualité du cadre de Claude Bernard qui met en avant le raisonnement expérimental comme catégorie englobante, plutôt qu’une distinction qui demeure toujours floue entre observation et expérience. (shrink)

En sciences biomédicales, diverses techniques d’imagerie permettent l’exploration d’organismes vivants, aussi bien pour le diagnostic que pour l’expérimentation. En se penchant sur l’une d’entre elles, la scintigraphie, on montre que l’utilisation d’un instrument complexe revêt toujours un caractère expérimental, même lorsque l’on entend l’utiliser à des fins d’observation diagnostique. La liste des tests qui sont à entreprendre sur la machine à diverses échelles de temps (quotidienne à annuelle) démontre que les chercheurs ne peuvent jamais l’utiliser en lui accordant leur confiance (...) de manière inconditionnelle. L’observation est encadrée par l’expérimentation, démontrant aussi l’actualité du cadre de Claude Bernard qui met en avant le raisonnement expérimental comme catégorie englobante, plutôt qu’une distinction qui demeure toujours floue entre observation et expérience. (shrink)

En sciences biomédicales, diverses techniques d’imagerie permettent l’exploration d’organismes vivants, aussi bien pour le diagnostic que pour l’expérimentation. En se penchant sur l’une d’entre elles, la scintigraphie, on montre que l’utilisation d’un instrument complexe revêt toujours un caractère expérimental, même lorsque l’on entend l’utiliser à des fins d’observation diagnostique. La liste des tests qui sont à entreprendre sur la machine à diverses échelles de temps démontre que les chercheurs ne peuvent jamais l’utiliser en lui accordant leur confiance de manière inconditionnelle. (...) L’observation est encadrée par l’expérimentation, démontrant aussi l’actualité du cadre de Claude Bernard qui met en avant le raisonnement expérimental comme catégorie englobante, plutôt qu’une distinction qui demeure toujours floue entre observation et expérience. (shrink)

In this paper, we carry out a critical analysis of the concept of technology in the current design of the bio-based economy (BBE). Looking at the current status of the BBE, we observe a dominant focus on technological innovation as the principal solution to climatic instability. We take a critical stance towards this “ecomodernist” worldview, addressing its fundamental assumptions, and ofer an underarticulated explanation as to why a successful transition toward a sustainable BBE—i.e. one that fully operates within the Earth’s (...) carrying capacity—has not yet been reached. Bernard Stiegler has developed a philosophical perspective on the concept of economy, broadening it to include the human condition through the notion of desire. This theory can help to obtain a more profound understanding of why ecomodernist strategies are dominant today. Stiegler’s theory of the libidinal economy ofers an analysis of controlled and exploited human desire as a primary driver behind modern techno-economic structures. Our hypothesis is that a critique of contemporary technofxism as a critique of libidinal economy is a necessary step to take in the discussion around the BBE as a concept, if the BBE is ever to bring about a system that can truly operate within the Earth’s carrying capacity. (shrink)

In this paper, we carry out a critical analysis of the concept of technology in the current design of the bio-based economy (BBE). Looking at the current status of the BBE, we observe a dominant focus on technological innovation as the principal solution to climatic instability. We take a critical stance towards this “ecomodernist” worldview, addressing its fundamental assumptions, and offer an underarticulated explanation as to why a successful transition toward a sustainable BBE—i.e. one that fully operates within the Earth’s (...) carrying capacity—has not yet been reached. Bernard Stiegler has developed a philosophical perspective on the concept of economy, broadening it to include the human condition through the notion of desire. This theory can help to obtain a more profound understanding of why ecomodernist strategies are dominant today. Stiegler’s theory of the libidinal economy offers an analysis of controlled and exploited human desire as a primary driver behind modern techno-economic structures. Our hypothesis is that a critique of contemporary technofixism _as_ a critique of libidinal economy is a necessary step to take in the discussion around the BBE as a concept, if the BBE is ever to bring about a system that can truly operate within the Earth’s carrying capacity. (shrink)

Ce texte a déjà paru le 21/12/2018 sur le site EspacesTemps.net. Nous remercions les auteurs et la revue EspacesTemps de nous avoir autorisé à le reproduire ici. Sans rythme pas de vie Bernard Millet La ville? « Ne pas essayer trop vite de trouver une définition de la ville ; c'est beaucoup trop gros, on a toutes les chances de se tromper ». Le rythme? Comment réussir « à définir un seul et même signifiant qui véhicule tant de signifiés (...) différents? ». Et - Géographie – Nouvel article. (shrink)

Un siècle d’historiennes, c’est sous ce titre qu’André Burguière et Bernard Vincent ont convié vingt auteurs à dresser le portrait de vingt historiennes, dix françaises et dix étrangères. À bien des égards, l’entreprise échappe à toute tentative de classification dans un genre historiographique précis. Il ne s’agit pas, dans l’esprit des maîtres d’œuvre, d’établir un palmarès des personnalités vivantes ou disparues ayant marqué le xxe siècle. L’ouvrage n’est pas non plus une socio-histoire qu...

This book closely examines our commonly held beliefs about human suffering, and offers unique insights into God's role in why we suffer. Dr. Perri critically examines what it means to be human from a Judeo-Christian perspective, and extrapolates from the work of Carl Gustav Jung showing a deeply complex development of human transcendence in human suffering. On an interpersonal level, Dr. Perri elaborates on the work of Martin Buber and Emanuel Levinas and shows how our suffering can be shared and (...) lessened by our unconditionality and presence for the other. Scriptural passages are quoted from both the Hebrew and New Testament texts, and are used to depict the suffering of humankind as seen in the face of Job. It was this face, according to Perri, that Jesus saw in the faces of those He came to redeem, and that ultimately brought Him to the crucifix of redemption. Dr. Perri challenges Sartre's position that our existence precedes our essence, and draws on the work of Abraham Joshua Heschel and Christian theology in this regard. He further elaborates a neurodevelopmental paradigm that creates essence as the basis of our freedom to choose. This book can be read and studied by both professionals in the helping and healing professions, and lay persons seeking to better understand our suffering, and how to better help those who suffer. Dr. Perri offers specific ways in how to be present for those who suffer, how to read and receive the hidden language of human suffering, and how to use silence as a communication skill. (shrink)

Will future lethal autonomous weapon systems (LAWS), or ‘killer robots’, be a threat to humanity? The European Parliament has called for a moratorium or ban of LAWS; the ‘Contracting Parties to the Geneva Convention at the United Nations’ are presently discussing such a ban, which is supported by the great majority of writers and campaigners on the issue. However, the main arguments in favour of a ban are unsound. LAWS do not support extrajudicial killings, they do not take responsibility away (...) from humans; in fact they increase the abil-ity to hold humans accountable for war crimes. Using LAWS in war would probably reduce human suffering overall. Finally, the availability of LAWS would probably not increase the probability of war or other lethal conflict—especially as compared to extant remote-controlled weapons. The widespread fear of killer robots is unfounded: They are probably good news. (shrink)

Traditionally, discussions of moral participation – and in particular moral agency – have focused on fully formed human actors. There has been some interest in the development of morality in humans, as well as interest in cultural differences when it comes to moral practices, commitments, and actions. However, until relatively recently, there has been little focus on the possibility that nonhuman animals have any role to play in morality, save being the objects of moral concern. Moreover, when nonhuman cases are (...) considered as evidence of moral agency or subjecthood, there has been an anthropocentric tendency to focus on those behaviors that inform our attributions of moral agency to humans. For example, some argue that the ability to evaluate the principles upon which a moral norm is grounded is required for full moral agency. Certainly, if a moral agent must understand what makes an action right or wrong, then most nonhuman animals would not qualify (and perhaps some humans too). However, if we are to understand the evolution of moral psychology and moral practice, we need to turn our attention to the foundations of full moral agency. We must first pay attention to the more broadly normative practices of other animals. Here, we begin that project by considering evidence that great apes and cetaceans participate in normative practices. (shrink)

In the mid twentieth century the philosopher Ludwig Wittgenstein famously asserted that games are indefinable; there are no common threads that link them all. "Nonsense," says the sensible Bernard Suits: "playing a game is a voluntary attempt to overcome unnecessary obstacles." The short book Suits wrote demonstrating precisely that is as playful as it is insightful, as stimulating as it is delightful. Suits not only argues that games can be meaningfully defined; he also suggests that playing games is a (...) central part of the ideal of human existence, so games belong at the heart of any vision of Utopia. Originally published in 1978, The Grasshopper is now re-issued with a new introduction by Thomas Hurka and with additional material (much of it previously unpublished) by the author, in which he expands on the ideas put forward in The Grasshopper and answers some questions that have been raised by critics. (shrink)

How I became a philosopher -- To love, to love me, to love us.

In this paper it is argued that existing ‘self-representational’ theories of phenomenal consciousness do not adequately address the problem of higher-order misrepresentation. Drawing a page from the phenomenal concepts literature, a novel self-representational account is introduced that does. This is the quotational theory of phenomenal consciousness, according to which the higher-order component of a conscious state is constituted by the quotational component of a quotational phenomenal concept. According to the quotational theory of consciousness, phenomenal concepts help to account for the (...) very nature of phenomenally conscious states. Thus, the paper integrates two largely distinct explanatory projects in the field of consciousness studies: (i) the project of explaining how we think about our phenomenally conscious states, and (ii) the project of explaining what phenomenally conscious states are in the first place. (shrink)

This paper investigates the prospects of Rodney Brooks’ proposal for AI without representation. It turns out that the supposedly characteristic features of “new AI” (embodiment, situatedness, absence of reasoning, and absence of representation) are all present in conventional systems: “New AI” is just like old AI. Brooks proposal boils down to the architectural rejection of central control in intelligent agents—Which, however, turns out to be crucial. Some of more recent cognitive science suggests that we might do well to dispose of (...) the image of intelligent agents as central representation processors. If this paradigm shift is achieved, Brooks’ proposal for cognition without representation appears promising for full-blown intelligent agents—Though not for conscious agents. (shrink)

Recent studies have shown that self‐explanation is an effective metacognitive strategy, but how can it be leveraged to improve students' learning in actual classrooms? How do instructional treatments that emphasizes self‐explanation affect students' learning, as compared to other instructional treatments? We investigated whether self‐explanation can be scaffolded effectively in a classroom environment using a Cognitive Tutor, which is intelligent instructional software that supports guided learning by doing. In two classroom experiments, we found that students who explained their steps during problem‐solving (...) practice with a Cognitive Tutor learned with greater understanding compared to students who did not explain steps. The explainers better explained their solutions steps and were more successful on transfer problems. We interpret these results as follows: By engaging in explanation, students acquired better‐integrated visual and verbal declarative knowledge and acquired less shallow procedural knowledge. The research demonstrates that the benefits of self‐explanation can be achieved in a relatively simple computer‐based approach that scales well for classroom use. (shrink)

In recent years, Charles Sanders Peirce has emerged, in the eyes of philosophers both in America and abroad, as one of America’s major philosophical thinkers. His work has forced us back to philosophical reflection about those basic issues that inevitably confront us as human beings, especially in an age of science. Peirce’s concern for experience, for what is actually encountered, means that his philosophy, even in its most technical aspects, forms a reflective commentary on actual life and on the world (...) in which it is lived. In Charles S. Peirce: On Norms and Ideals, Potter argues that Peirce’s doctrine of the normative sciences is essential to his pragmatism. No part of Peirce’s philosophy is bolder than his attempt to establish esthetics, ethics, and logic as the three normative sciences and to argue for the priority of esthetics among the trio. Logic, Potter cites, is normative because it governs thought and aims at truth; ethics is normative because it analyzes the ends to which thought should be directed; esthetics is normative and fundamental because it considers what it means to be an end of something good in itself. This study shows that pierce took seriously the trinity of normative sciences and demonstrates that these categories apply both to the conduct of man and to the workings of the cosmos. Professor Potter combines sympathetic and informed exposition with straightforward criticism and he deals in a sensible manner with the gaps and inconsistencies in Peirce’s thought. His study shows that Peirce was above all a cosmological and ontological thinker, one who combined science both as a method and as result with a conception of reasonable actions to form a comprehensive theory of reality. Peirce’s pragmatism, although it has to do with "action and the achievement of results, is not a glorification of action but rather a theory of the dynamic nature of things in which the "ideal" dimension of reality – laws, nature of things, tendencies, and ends – has genuine power for directing the cosmic order, including man, toward reasonable goals. (shrink)

" Façonner le monde atome par atome " : tel est l'objectif incroyablement ambitieux affiché par les promoteurs américains de la " National Nanoinitiative ", lancée en 1999. Un projet global de " convergence des sciences ", visant à " initier une nouvelle Renaissance, incorporant une conception holiste de la technologie fondée sur [..] une analyse causale du monde physique, unifiée depuis l'échelle nano jusqu'à l'échelle planétaire. " Ce projet démiurgique est aujourd'hui au coeur de ce qu'on appelle la " (...) technoscience ", étendard pour certains, repoussoir pour d'autres. En précisant dans ce livre la signification de ce concept, pour sortir enfin du sempiternel conflit entre technophiles et technophobes, son auteur propose d'abord une sorte d'archéologie du terme " technoscience ". Loin d'être un simple renversement de hiérarchie entre science et technique, il s'agit d'un changement de régime de la connaissance scientifique, ayant désormais intégré la logique entrepreneuriale du monde des affaires et mobilisant des moyens considérables. Surtout, Bernadette Bensaude-Vincent montre que le brouillage de la frontière entre science et technique n'est que la manifestation d'un tremblement plus général, marqué par l'effacement progressif des distinctions traditionnelles : nature/artifice, inerte/vivant, matière/esprit, homme/machine, etc. Alors que nos sociétés sont silencieusement reconfigurées par les nanotechnologies, Internet, le génie génétique ou les OGM, ce livre montre l'importance de faire enfin pleinement entrer les questions de choix technologiques et scientifiques dans la sphère du politique et dans l'arène publique. Car la technoscience est un processus historique qui engage la nature en la refaçonnant et qui implique la société dans son ensemble. (shrink)

In philosophical reflections on geoethics, it is primarily the question of what it means to be ‘part’ of the Earth system that is critically reflected upon. As the current geological era of the Anthropocene disrupts the dichotomy between Human agency and the Earth system, philosophers criticise a humanist account of geoethics and call for a post-humanist account. In this chapter, we critically engage with one specific proponent of the post-humanist position, Timothy Morton. We introduce his version of the post-humanist position (...) by focussing on his call for the ‘end-of-the-world’ in the Anthropocene. We subsequently criticise Morton’s rejection of the World for three reasons. We show that the emergence of the Anthropocene is primarily an ontological phenomenon, namely a shift in our ‘being-in-the-world’ and that the concept of World is needed to understand the meaning of our ‘being-in-the-Anthropocene’ in contrast with our ‘being-in-the-Holocene’. We introduce a twofold between our ‘being-in-the-world’ as a symmetric relation and our ‘being-on-Earth’ as an asymmetric relation that constitutes our ‘being-in-the-Anthropocene’. This asymmetry disrupts the post-humanist position and calls for a conceptualisation of the human ethos beyond the post-humanist position. This conceptualisation of the human ethos also has consequences for our understanding of geoethics as geo-ethos. (shrink)

" La formule cartésienne causa sive ratio scande l'histoire de la causalité, entre le privilège suarézien de la cause efficiente et l'invention leibnizienne du principe de raison suffisante. Elle traverse un siècle exactement, des Disputationes metaphysicae de Suarez (1597) aux 24 thèses métaphysiques de Leibniz (1697). La métaphysique s'y constitue en époque de la causalité. Qu'ils la soutiennent ou qu'ils la récusent, les philosophes du XVIIe siècle ont en commun de discuter la thèse qui confère l'intelligibilité à la relation causale (...) ; elle prend la forme exemplaire de l'équivalence cartésienne de la cause et de la raison. Mais la façon dont la relation causale gagne l'intelligibilité demeure à son tour inintelligible, puisqu'elle renvoie à la toute-puissance incompréhensible de celui qui l'exerce, y compris peut-être envers lui-même : sui causa. C'est là précisément la thèse que les post-cartésiens ne cesseront de lire comme un problème et de récuser : Spinoza, en posant que l'ordre et la connexion des idées sont les mêmes que l'ordre et la connexion des choses ; Malebranche, en faisant de la cause occasionnelle une raison inefficace et en concentrant en Dieu toute l'efficace ; Leibniz, en employant le principe de raison suffisante, qui rationalise l'existence en la soustrayant à l'emprise de l'efficience. Loin de la produire, la causalité se voit alors soumise, sous diverses modalités, à l'intelligibilité. Aussi le principe de raison suffisante signe-t-il ce que nous appelons la fin de la cause - par excellence la fin de l'efficience -, qui n'est pas la fin de la question du fondement, mais le déplacement de sa réponse vers plus fondateur que la cause : la raison. Ainsi se trouve accomplie l'essence du fondement à l'époque moderne de l'histoire de la métaphysique. " V. C. (shrink)

This book offers the fullest and most sophisticated account of Gert's influential moral theory, a model first articulated in the classic work The Moral Rules: A New Rational Foundation for Morality, published in 1970. In this final revision, Gert makes clear that the moral rules are only one part of an informal system that does not provide unique answers to every moral question but does always provide a range of morally acceptable options. A new chapter on reasons includes an account (...) of what makes one reason better than another and a second new chapter is devoted to the question of justifying violations of the rules. Moral impartiality, the moral ideals, and virtue and vice, are all treated in greater detail. Throughout, Gert attempts to answer all of the challenges that his work has provoked. (shrink)

An updated and expanded successor to Culver and Gert's Philosophy in Medicine, this book integrates moral philosophy with clinical medicine to present a comprehensive summary of the theory, concepts, and lines of reasoning underlying the ...

part 1. An annotated translation of Pramāṇavārttikasvavṛtti 24,16-45,20 (Pramāṇavārttika 1.40-91.

what is the ontology of planets?Our access point to this question is the ontology of planet Earth. Although the presence of life marks planet Earth as special among other planets, Earth shares a basic commonality with them – namely, its material existence. We take this commonality as a point of departure for our reflections on the ontology of both planet Earth and other planets. In this chapter, we ask for the ontology of this materiality of planets. We consult the ontology (...) of planet Earth as I developed it in an earlier contribution (Blok, 2019), explore the ontology of planets as absolute boundary of the natural habitats on Earth, and reflect on the opportunities and limitations such ontology provides for future human colonies on other planets. (shrink)