This paper explores the truism that people think about what they say. It proposes that, to satisfy their own goals, people often plan their speech acts to affect their listeners' beliefs, goals, and emotional states. Such language use can be modelled by viewing speech acts as operators in a planning system, thus allowing both physical and speech acts to be integrated into plans. Methodological issues of how speech acts should be defined in a planbased theory are illustrated by defining operators (...) for requesting and informing. Plans containing those operators are presented and comparisons are drawn with Searle's formulation. The operators are shown to be inadequate since they cannot be composed to form questions (requests to inform) and multiparty requests (requests to request). By refining the operator definitions and by identifying some of the side effects of requesting, compositional adequacy is achieved.The solution leads to a metatheoretical principle for modelling speech acts as planning operators. (shrink)

Metaphors used to describe new technologies mediate public understanding of the innovations. Analyzing the linguistic, rhetorical, and affective aspects of these metaphors opens the range of issues available for bioethical scrutiny and increases public accountability. This article shows how such a multidisciplinary approach can be useful by looking at a set of texts about one issue, the use of a newly developed technique for genetic modification, CRISPRcas9.

This is a good time for determinists. One hundred and fifty years of Darwinian thought have undermined belief in the exceptional status of human beings. Biological reductionism is in the ascendant. One of its most recent manifestations—evolutionary psychology, which has been widely influential both within and beyond academe—argues that individual behaviour and even social institutions are expressions of genes, the vast majority of which are common to humans and the higher primates. The implicit, largely unconscious, principles that inform gene-determined human (...) behaviour are rooted in their survival value; and the entity whose survival is served is not the conscious organism but the genome itself. Since the actual reasons for our actions are beyond our ken, they are not truly voluntary. Yet more radical attacks on the notion of human freedom have come from neuroscience: ever more sophisticated and seemingly complete accounts of the human mind in terms of the functioning of our brains, appear to embed even higher level awareness in the material world. (shrink)

This is a good time for determinists. One hundred and fifty years of Darwinian thought have undermined belief in the exceptional status of human beings. Biological reductionism is in the ascendant. One of its most recent manifestations—evolutionary psychology, which has been widely influential both within and beyond academe—argues that individual behaviour and even social institutions are expressions of genes, the vast majority of which are common to humans and the higher primates. The implicit, largely unconscious, principles that inform gene-determined human (...) behaviour are rooted in their survival value; and the entity whose survival is served is not the conscious organism but the genome itself. Since the actual reasons for our actions are beyond our ken, they are not truly voluntary. Yet more radical attacks on the notion of human freedom have come from neuroscience: ever more sophisticated and seemingly complete accounts of the human mind in terms of the functioning of our brains, appear to embed even higher level awareness in the material world. (shrink)

Some have characterized patients living with intractable pain as a vulnerable population in both clinical and research settings. Labeling the population as vulnerable, however, does not provide clarity regarding the potential risks that they face when they participate in research. Instead, research vulnerability for patients in pain is a function of an interaction between their pain conditions and elements of the research enterprise. Therefore, the identification of potential risks requires consideration not only of characteristics of patients with chronic pain, but (...) also consideration of features of researchers, the quality of institutional oversight, and the medical/social environment within which the research is conducted. This paper provides an analysis of those risks and provides some suggestions as to how the risks might be better managed. (shrink)

The concept of vulnerability has been the topic of considerable discussion in research bioethics, largely because of dissatisfaction with early constructions of the concept that were based on subpopulations of research subjects. These subpopulations have attributes likely to undermine their capacity to provide autonomous informed consent: persons who are relatively or absolutely incapable of protecting their own interests through negotiations for informed consent. Several subpopulations were seen as requiring special protections, including children, pregnant women, prisoners, racial minorities, the economically disadvantaged, (...) the very sick, and the institutionalized. Recent years have witnessed the identification of other subpopulations with attributes that could render them vulnerable, as well. For example, the Council for the International Organization of Medical Societies has named such potentially vulnerable groups as the homeless, nursing home residents, patients with incurable diseases, patients in the emergency department, employees, students, and members of communities who are unfamiliar with modern medicine. (shrink)

This four-volume set presents an unrivalled collection of the key literature in European sociology. The prestigious texts range across the European tradition from enlightenment to contemporary theory. The collection explodes the myth that the European tradition in sociology is a debate with the ghosts of Karl Marx and Max Weber, demonstrating that the tradition is far more deeply rooted and broadly based. Volume 1 is devoted to the emergence of European sociology. The contribution of classical political economy and the Enlightenment (...) is examined. Commentaries on the work of Hobbes, Locke, Montesquieu, Taine, Rousseau, de Tocqueville, Comte and St. Simon are included. The volume creates a vivid and compelling picture of the origins of European sociology. Volume 2 covers the rise of the classical period in social theory. It includes commentaries on the contribution of Marx, Spencer, Dilthey, Weber, Durkheim and Simmel. An overview of the main contributions of the founding fathers is also included. Volume 3 moves on to explore the main developments in the first half of the twentieth century. The contributions of the Durkheimian Tradition, Mauss, Mannheim, Lukacs, Gramsci and British sociology are presented. The volume provides a synoptic view of the diversity and emerging complexity of European sociology. Volume 4 identifies the main developments from post-industrial theory to the present day. The volume includes commentaries on the work of Aron, Foucault, Habermas, Giddens, Bourdieu, Boudon and Gellner. Selections on structuralism, polysemy, the positivist dispute and the neo-liberal tradition widen out the picture. The collection is the benchmark work for understanding the history, contribution and dilemmas of the European tradition. Full account is taken of the reference needs of students as well as of academics. Each hardcover volume of 416 pages is bound to the highest standards. The lettering on the cover is gold embossed. The slip case for the four volumes is also embossed. The volumes are not available separately. (shrink)

This book details the results of the authors' research using laboratory animals to investigate individual choice theory in economics-consumer-demand and labour supply behaviour and choice under uncertainty. The use of laboratory animals provides the opportunity to conduct controlled experiments involving precise and demanding tests of economic theory with rewards and punishments of real consequence. Economic models are compared to psychological and biological choice models along with the results of experiments testing between these competing explanations. Results of animal experiments are used (...) to address questions of social policy importance. (shrink)

Many critics seem to consider it inappropriate or unnecessary to ask what Montaigne means by the faculty of judgment. Laumonier speaks of "Ie bon sens, qu'il oppose si souvent a la memoire et qu'il appelle encore 'jugement' et 'entendement', c'est-a-dire la faculte de penser et de reflechir juste. " 1 Our appreciation of what is implied by judgment, that is by Montaigne's notion of judgment, has been delayed perhaps by a too facile acceptance of a so-called synonymity of meaning among (...) the psychological terms used by Montaigne. In a discussion of key concepts in Montaigne, Donald M. Frame has accurately summarized the present situation with regard to our knowledge of Montaigne's notion of judgment and other key concepts: "We all have our hunches, but we need more than that. " 2 For the expression of his interest and concern for the intellectual and moral activities and capabilities of the mind, Montaigne draws upon a broad and elementary semantic field. These primary psychological terms are jugement, entendement, sens, raison, discours, and conscience. Al­ though these words may be used synonymously, Montaigne does seem to maintain certain basic distinctions among them; frequent substi­ tutions of terms must be the result of semantic and ideational differ­ ences. Moreover, the association of several psychological words within a single sentence implies gradations, however slight they may be. (shrink)

Inattentional blindness is described as the failure to perceive a supra-threshold stimulus when attention is directed away from that stimulus. Based on performance on an explicit recognition memory test and concurrent functional imaging data Rees, Russell, Frith, and Driver [Rees, G., Russell, C., Frith, C. D., & Driver, J. . Inattentional blindness versus inattentional amnesia for fixated but ignored words. Science, 286, 2504–2507] reported inattentional blindness for word stimuli that were fixated but ignored. The present study examined both explicit and (...) implicit memory for fixated but ignored words using a selective-attention task in which overlapping picture/word stimuli were presented at fixation. No explicit awareness of the unattended words was apparent on a recognition memory test. Analysis of an implicit memory task, however, indicated that unattended words were perceived at a perceptual level. Thus, the selective-attention task did not result in perfect filtering as suggested by Rees et al. While there was no evidence of conscious perception, subjects were not blind to the implicit perceptual properties of fixated but ignored words. (shrink)

We reconsider the consequences of the observed violations of Bell's inequalities. Two common responses to these violations are (i) the rejection of realism and the retention of locality and (ii) the rejection of locality and the retention of realism. Here we critique response (i). We argue that locality contains an implicit form of realism, since in a worldview that embraces locality, spacetime, with its usual, fixed topology, has properties independent of measurement. Hence we argue that response (i) is incomplete, in (...) that its rejection of realism is only partial. (shrink)

Hand function improvement in stroke survivors in the chronic stage usually plateaus by 6 months. Brain-computer interface (BCI)-guided robot-assisted training has been shown to be effective for facilitating upper-limb motor function recovery in chronic stroke. However, the underlying neuroplasticity change is not well understood. This study aimed to investigate the whole-brain neuroplasticity changes after 20-session BCI-guided robot hand training, and whether the changes could be maintained at the 6-month follow-up. Therefore, the clinical improvement and the neurological changes before, immediately after, (...) and 6 months after training were explored in 14 chronic stroke subjects. The upper-limb motor function was assessed by Action Research Arm Test (ARAT) and Fugl-Meyer Assessment for Upper-Limb (FMA), and the neurological changes were assessed using resting-state functional magnetic resonance imaging. Repeated-measure ANOVAs indicated that long-term motor improvement was found by both FMA (F[2,26]= 6.367,p= 0.006) and ARAT (F[2,26]= 7.230,p= 0.003). Seed-based functional connectivity analysis exhibited that significantly modulated FC was observed between ipsilesional motor regions (primary motor cortex and supplementary motor area) and contralesional areas (supplementary motor area, premotor cortex, and superior parietal lobule), and the effects were sustained after 6 months. The fALFF analysis showed that local neuronal activities significantly increased in central, frontal and parietal regions, and the effects were also sustained after 6 months. Consistent results in FC and fALFF analyses demonstrated the increase of neural activities in sensorimotor and fronto-parietal regions, which were highly involved in the BCI-guided training.Clinical Trial Registration:This study has been registered atClinicalTrials.govwith clinical trial registration number NCT02323061. (shrink)

Most Americans today view mines as little more than ugly scars on the landscape, places with no connection to an American way of life. This creative new work will force many to rethink that impression: after an introduction to the history of mining in America, the authors present eight visual and historical essays about diverse sites across the nation, each of which reveals mines not simply as physical degradations but as evolving cultural artifacts of the American landscape.

The precarious rights of senior citizens, especially those who are highly educated and who are expected to counsel and guide the younger generations, has stimulated the creation internationally of advocacy associations and opinion leader groups. The strength of these groups, however, varies from country to country. In some countries, they are supported and are the focus of intense interest; in others, they are practically ignored. For this is reason we believe that the creation of a network of all these associations (...) is essential. The proposed network would act as a support for the already-existing policies of the United Nations’ High Commission for Human Rights, of independent experts, and of the Global Alliance for the Rights of Older People. All three have long ago recommended the creation of a recognized instrument for uniting presently scattered efforts. The proposed network, therefore, will seek to promote the international exchange of relevant expertise, and it will reinforce the commitments and actions that single countries are currently taking to meet these objectives. For example, informative public events can be organised to promote particular support initiatives and to provide an opportunity for new members of the network to be presented. The network will promote health for senior citizens, disease prevention, senior mobility, safe free time for seniors, alimentary education, protection against new risks and dangers, as well as equity in the services necessary for seniors to adopt new information and communication technologies. In the case of retired academic members, the network will promote equality with respect to continuing use of digital technologies (particularly email), continuing access to research libraries, and the guaranteed ability for seniors to fund their own research programs and to deliver free seminars. (shrink)