What have tissue culture studies told us about the development of oligodendrocytes?

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Bioessays 14 (10):693-698 (1992)
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Abstract

One major success of studying neural cell development in tissue culture has been the discovery of the O‐2A cell. This bipotential cell generates oligodendrocytes or, under certain conditions, a type of astrocyte. This essay considers the evidence that the characteristic properties demonstrated by the O‐2A cells in vitro are an accurate reflection of oligodendrocyte development in vivo.

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10.1002/bies.950141010

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