Abstract
The history of life on Earth has been shaken in the last half billion years by five mass extinctions that have killed at least three-quarters of biodiversity in a geologically short time. These five extinctions were due to major ecological upheavals, with endogenous or exogenous drivers (volcanic eruptions, impact of asteroids, etc.). Today, many data show that the current extinction rate is comparable to or even worse than that of the Big Five mass extinctions of the past. The difference is that this time the asteroid is one species: Homo sapiens. There are good reasons to include the Sixth Mass Extinction in the definition of the Anthropocene. This drastic reduction in biodiversity will leave an irreversible geological and paleontological mark. It interacts with climate change, with a multiplicative effect. It contributes to the environmental crisis that reduces ecosystem services and threatens human health (i.e., likelihood of spillovers).