Bioessays 27 (12):1213-1217 (
2005)
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Abstract
Back‐to‐back papers have described the identification of a family of receptors for the plant hormone auxin.(1, 2) Most developmental processes in plants are dependent on auxin signalling making this discovery a landmark in the search for the mechanism of auxin action. The TIR1 gene translates into a protein with recognised motifs including an F‐box domain and TIR1 forms part of an important ubiquitination complex that tags other proteins for degradation.(3) Specific amongst the targets of TIR1 are a set of auxin‐regulated transcription factors.(4) The latest work has shown that TIR1 itself is also the binding site for auxin making it an auxin receptor with no requirement for a biochemical signalling cascade. BioEssays 27:1213–1217, 2005. © 2005 Wiley Periodicals, Inc.