Gene therapy, regulatory mechanisms, and protein function in vision

Behavioral and Brain Sciences 18 (3):481-482 (1995)
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Abstract

Hereditary retinal degeneration due to mutations in visual genes may be amenable to therapeutic interventions that modulate, either positively or negatively, the amount of protein product. Some of the proteins involved in phototransduction are rapidly moved by a lightdependent mechanism between the inner segment and the outer segment in rod photoreceptor cells, and this phenomenon is important in phototransduction

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