Abstract
In this paper I explore an underdiscussed factor contributing to the replication crisis: Scientists, and following them policy makers, often neglect sources of errors in the production and interpretation of data and thus overestimate what can be learnt from them. This neglect leads scientists to conduct experiments that are insufficiently informative and science consumers, including other scientists, to put too much weight on experimental results. The former leads to fragile empirical literatures, the latter to surprise and disappointment when the fragility of the empirical basis of some disciplines is revealed.