Paralogs and mutational robustness linked through transcriptional reprogramming

Bioessays 27 (9):865-868 (2005)
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Abstract

A recent analysis of genome‐wide expression patterns and regulatory motif content of paralogous yeast genes1 strongly suggests that mutational robustness (backup) between paralogous genes is achieved via transcriptional reprogramming of one paralog to compensate for the loss or silencing of the other. BioEssays 27:865–868, 2005. Published 2005 Wiley Periodicals, Inc.

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10.1002/bies.20296

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