Objectives: To explore how subjects in a placebo-controlled vitamin A supplementation trial among Ghanaian women aged 15–45 years perceive the trial and whether they know that not all trial capsules are the same, and to identify factors associated with this knowledge.Methods: 60 semistructured interviews and 12 focus groups were conducted to explore subjects’ perceptions of the trial. Steps were taken to address areas of low comprehension, including retraining fieldworkers. 1971 trial subjects were randomly selected for a survey measuring their knowledge (...) that not all trial capsules are the same. The subjects’ fieldworkers were also interviewed about their characteristics and trial knowledge. Factors associated with knowledge were explored using multi-level modeling.Results: Although subjects knew they were taking part in research, most thought they were receiving an active and beneficial medication. Variables associated with knowledge were education and district of residence. Radio broadcasts benefited those with some schooling. Fieldworkers’ characteristics were not associated with subjects’ knowledge.Conclusions: Research and debate on new or improved consent procedures are urgently required, particularly for subjects with little education. (shrink)

The pigment melanin is found in all living kingdoms and in many different structures and forms. When its various functions are examined separately, its behaviors seem disparate and conflicting. It has a clear role in camouflage and sexual display. Other major roles are examined critically. It can act as a sun screen but is not a very effective one. It can also scavenge active chemical species, but this, too, is not done very effectively. It produces active radicals that can damage (...) DNA. It binds to drugs in ways that are either beneficial or deleterious. Aside from camouflage, its other roles can be brought together by a unifying hypothesis as first proposed by Proctor and McGinness nearly 20 years ago. Melanin is envisaged as an energy transducer with the properties of an amorphous semiconductor. It can absorb many different types of energy and dissipate them in the form of heat. However, if the energy input is too great, the output can be expressed in the form of activated chemical species that can damage cellular macromolecules resulting in cell death, mutations and cancer. The protective aspect of melanin in dark skin is seen as resulting from its high concentration and its confinement to ellipsoidal and densely packed organelles that can effectively shield the nucleus. In light skin, its radical nature is seen as potentially participating in the carcinogenic process, particularly when overwhelmed by intense episodes of sunburn. (shrink)

The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

A handy guide to the major figures and issues in Christian philosophy from Augustine to the present.This volume covers a broad historical sweep and takes into account those non-Christian philosophers that have had a great impact on the Christian tradition. However, it concentrates on the issues that perplex Christian philosophers as they seek to think through their faith in a philosophical way and their philosophical beliefs in the light of their faith. Examples of the topics discussed are the question of (...) whether and how God knows the future, whether we actually know that God exists, and what Athens has to do with Jerusalem. The leaders of the recent revival of Christian analytic philosophy, especially Alvin Plantinga, Nicholas Wolterstorff, William Alston, and Robert Adams are also included. (shrink)

Predictions concerning the end of the world have proven less reliable than your broker’s recommendations or your fondest hopes. Whether you await the end fearfully or eagerly, you may rest assured that it will never come—not because the world is everlasting but because it has already ended, if indeed it ever began. But we need not mourn, for the world is indeed well lost, and with it the stultifying stereotypes of absolutism: the absurd notions of science as the effort to (...) discover a unique, prepackaged, but unfortunately undiscoverable reality, and of truth as agreement with that inaccessible reality. All notions of pure givenness and unconditional necessity and of a single correct perspective and system of categories are lost as well.If there is no such thing as the world, what are we living in? The answer might be “A world” or, better, “Several worlds.” For to deny that there is any such thing as the world is no more to deny that there are worlds than to deny that there is any such thing as the number between two and seven is to deny that there are numbers between two and seven. The task of describing the world is as futile as the task of describing the number between two and seven.The world is lost once we appreciate a curious feature of certain pairs of seemingly contradictory statements: if either is true, both are. Although “The earth is in motion” and “The earth is at rest” apparently contradict each other, both are true. But from a contradiction, every statement follows. So unless we are prepared to acknowledge the truth of every statement, the appearance of contradiction in cases like these must somehow be dispelled. Nelson Goodman is professor emeritus of philosophy at Harvard University. He has written Of Mind and Other Matters, Ways of Worldmaking, Problems and Projects, Languages of Art, The Structure of Appearance, and Fact, Fiction, and Forecast. His most recent contribution to Critical Inquiry is “How Buildings Mean” . Catherine Z. Elgin is associate professor of philosophy at the University of North Carolina, Chapel Hill. She is the author of With Reference to Reference and is currently writing a book entitled Philosophy without Foundations. (shrink)

The Z‐conformation, recently elucidated in crystals of synthetic alternating dG‐dC polymers, is a dramatically different structure for DNA. Despite suggestive locations of alternating purine‐pyrimidine tracts in chromosomes and intriguing functional hypotheses, unequivocal demonstrations of the Z‐conformation in vivo are not proving easy. Perhaps the Z‐conformation should be considered largely as a dynamic structure transiently forming in torsionally stressed chromatin.

When I was asked to review this book, I thought it was to be a single essay, since the title gave no indication that the relation of David Lyons to the book was that of editor to a collection to which he also contributes. Most of the essays are so well known that no descriptive comment is necessary and no critical one adequate in a review of this length. The essays included are as follows: H. L. A. Hart's "Are There (...) Any Natural Rights?" and "Bentham on Legal Rights"; Rawls on "Constitutional Liberty and the Concept of Justice" which anticipates the central position of his A Theory of Justice; Richard Wasserstrom on "Rights, Human Rights and Racial Discrimination"; Joel Feinberg on "The Nature and Value of Rights"; Ronald Dworkin "Taking Rights Seriously"; Thomas E. Hill, Jr., "Servility and Self-Respect"; Robert Nozick, "The Entitlement Theory"; David Lyons's "Rights, Claimants and Beneficiaries" and "Human Rights and the General Welfare". David Lyons also has a useful introduction which raises and discusses the main points in the essays. (shrink)

Thomas Hill, a leading figure in the recent development of Kantian moral philosophy, presents a set of essays exploring the implications of basic Kantian ideas for practical issues. The first part of the book provides background in central themes in Kant's ethics; the second part discusses questions regarding human welfare; the third focuses on moral worth-the nature and grounds of moral assessment of persons as deserving esteem or blame. Hill shows moral, political, and social philosophers just how valuable (...) moral theory can be in addressing practical matters. (shrink)

This stimulating collection of essays in ethics eschews the simple exposition and refinement of abstract theories. Rather, the author focuses on everyday moral issues, often neglected by philosophers, and explores the deeper theoretical questions which they raise. Such issues are: Is it wrong to tell a lie to protect someone from a painful truth? Should one commit a lesser evil to prevent another from doing something worse? Can one be both autonomous and compassionate? Other topics discussed are servility, weakness of (...) will, suicide, obligations to oneself, snobbery, and environmental concerns. A feature of the collection is the contrast of Kantian and utilitarian answers to these problems. The essays are crisply and lucidly written and will appeal to both teachers and students of philosophy. (shrink)

Respect, Pluralism, and Justice is a series of essays which sketches a broadly Kantian framework for moral deliberation, and then uses it to address important social and political issues. Hill shows how Kantian theory can be developed to deal with questions about cultural diversity, punishment, political violence, responsibility for the consequences of wrongdoing, and state coercion in a pluralistic society.

The modal account of luck is the predominant account of luck in epistemology and ethics. In the first half of this paper, I discuss three possible interpretations of the modal account and raise objections to each. I then raise an objection to all plausible versions of the modal account, that is, that whether an event is lucky or the extent to which it is a matter of luck will depend on what initial conditions or features of the event one holds (...) constant across nearby possible worlds. However, there is often reasonable disagreement about what the relevant initial conditions of an event are, and the modal account of luck has no means of determining which description of the event is correct. As such, the modal account is subject to a kind of reference class problem, and the view cannot actually tell us the extent to which certain events are a matter of luck. (shrink)

In this provocative and original work, Slavoj Zizek takes a look at the question of human agency in a postmodern world. From the sinking of the Titanic to Hitchcock's Rear Window, from the operas of Wagner to science fiction, from Alien to the Jewish Joke, the author's acute analyses explore the ideological fantasies of wholeness and exclusion which make up human society. Linking key psychoanalytical and philosophical concepts to social phenomena such as totalitarianism and racism, the book explores the political (...) significance of these fantasies of control. In so doing, The Sublime Object of Ideology represents a powerful contribution to a psychoanalytical theory of ideology, as well as offering persuasive interpretations of a number of contemporary cultural formations. -- Back cover. (shrink)

The Beloved Self is about the holy grail of moral philosophy, an argument against egoism that proves that we all have reasons to be moral. Part One introduces three different versions of egoism. Part Two looks at attempts to prove that egoism is false, and shows that even the more modest arguments that do not try to answer the egoist in her own terms seem to fail. But in part Three, Hills defends morality and develops a new problem for egoism, (...) an epistemological problem. She shows that it is not epistemically rational to believe the most plausible versions of egoism. The first part of the book will be most relevant to those interested in moral theory, as it contains detailed discussions of recent interpretations of virtue ethics and especially of Kant's moral theory. The second and third part of the book turn to epistemology, particularly moral epistemology, and include an account of the relationship between knowledge and action, a new theory of moral understanding, and a discussion of the epistemically rational response to various kinds of disagreement. Hills also defends a new account of virtue and of morally worthy action. (shrink)

In Algorithms & Autonomy, Rubel, Castro, and Pham (hereafter RCP), argue that the concept of autonomy is especially central to understanding important moral problems about algorithms. In particular, autonomy plays a role in analyzing the version of social contract theory that they endorse. I argue that although RCP are largely correct in their diagnosis of what is wrong with the algorithms they consider, those diagnoses can be appropriated by moral theories RCP see as in competition with their autonomy based theory. (...) Most notably, proponents of consequentialism and virtue ethics can appropriate RCPs insights. This is good news because RCP’s social contract theory is vulnerable to a well known class of counterexamples. The most significant contribution of RCP, if I am right, is in their identification, presentation, and evaluation of concrete cases involving algorithms and not in the more controversial claims about theoretical ethics that RCP themselves see as central to what they are doing. (shrink)

Kevin Hill presents a highly original study of Nietzsche's thought, the first book to examine in detail his debt to the work of Kant. Hill argues that Nietzsche is a systematic philosopher who knew Kant far better than is commonly thought, and that he can only be properly understood in relation to him. Nietzsche's Critiques will be of great value to scholars and students with interests in either of these philosophical giants, or in the history of ideas generally.

It has been suggested that we turn to solar geoengineering to counter global warming, which would consequently transform the relationship of terrestrial plant-life to the sun. This is an article not about geoengineering as such, but instead what is called photosynethics, or, thinking about our moral relationship to the light – in particular, as it is mediated by plants. Working from within but then extending the idea of responsibility found in the work of Emmanuel Levinas, it is argued here that, (...) since the plant cultivates the conditions of life on earth by photosynthesis, its relationship to the sun is then a relation of giving to others that is properly moral. The plant’s existence is an exposure so out of kilter with human ways of understanding existence that it interrupts our own and brings us into a relation of responsibility. It is concluded that rather than redirecting the sun’s radiation, we should turn to plants to reconsider how we live with the light on a heating planet. This first means separating moral responsibility from human vision so that we might encounter light on its own terms, and not simply as an element of rationality or sentiment or discipline. (shrink)

Philosophies of Difference engages with the concept of difference in relation to a number of fundamental philosophical and political problems. Insisting on the inseparability of ontology, ethics and politics, the essays and interview in this volume offer original and timely approaches to thinking nature, sexuate difference, racism, and decoloniality. The collection draws on a range of sources, including Latin American Indigenous ontologies and philosophers such as Henri Bergson, Jacques Derrida, Luce Irigaray, Immanuel Kant, Maurice Merleau-Ponty, Charles Mills, and Eduardo Viveiros (...) de Castro. -/- The contributors think embodiment and life by bringing continental philosophy into generative dialogue with fields including plant studies, animal studies, decoloniality, feminist theory, philosophy of race, and law. Affirming the importance of interdisciplinarity, Philosophies of Difference contributes to a creative and critical intervention into established norms, limits, and categories. Invoking a conception of difference as both constitutive and generative, this collection offers new and important insights into how a rethinking of difference may ground new and more ethical modes of being and being-with. Philosophies of Difference unearths the constructive possibilities of difference for an ethics of relationality, and for elaborating non-anthropocentric sociality. -/- The chapters in this book were originally published in a special issue in Australian Feminist Law Journal. (shrink)

Husserl and Cantor were colleagues and close friends during the last 14 years of the nineteenth century, when Cantor was at the height of his creative powers and Husserl in the throes of an intellectual struggle during which he drew apart from people and writings to whom he owed most of his intellectual training and drew closer to the ideas of thinkers whose writings he had not been able to evaluate properly and had consulted too little. I study ways in (...) which Husserl and Cantor might be said to have been alike, while pointing to dissimilarities between them. In particular, I discuss how their ideas overlapped and crisscrossed with regard to mathematics and philosophy, Platonic idealism, abstraction, empiricism, psychologism, actual consciousness and pure logic, Frege’s reviews of their works, metaphysics and mysticism, sets, arithmetization, strange and imaginary numbers and manifolds. I conclude that Cantor was among those of his mentors from whose ideas Husserl drew away and Lotze and Bolzano were among those to whose ideas he drew closer. (shrink)

Epistemic accounts of luck define luck’s chanciness condition relative to a subject’s epistemic position. This could be put in terms of a subject’s evidence or knowledge about whether the event will occur. I argue that both versions of the epistemic account fail. In §2, I give two types of counterexamples to the evidence-based approach. In §3, I argue—contrary to the knowledge-based view—that an event can be a matter of good or bad luck for a subject even if she knows that (...) it will occur. In §4, I argue that epistemic accounts cannot explain some instances of constitutive luck. Because of these problems, luck’s chanciness condition cannot be adequately defined in epistemic terms. (shrink)

In this investigation of Christian thinkers, selected philosophers, and other religious leaders, key issues regarding Christianity over the centuries are discussed in detail. Considering the arguments for and against each position, the study's perspective focuses on the key questions of life and existence, showing the different ways Christian thinkers have answered them. Providing an excellent way into understanding these issues and having readers formulate opinions for themselves, the collection of questions include: How can we believe in God when there is (...) so much suffering? Does science mean the end of religion? Does life after death really exist? Have we any good reason to believe in God? What is the ultimate goal of life? and What does it mean to lead a good life? (shrink)

In Less Than Nothing, the pinnacle publication of a distinguished career, Slavoj i ek argues that it is imperative that we not simply return to Hegel but that we repeat and exceed his triumphs, overcoming his limitations by being even more ...

It is often assumed that all lucky events are significant. The thought is that a chancy event such as winning the lottery is lucky for you in part because it affects your interests or well-being. But whether you win an Absurdist Raffle in which there are no prizes, is, intuitively, not a matter of luck. This is because this event—even if chancy—is not significant for any subject. However, a few philosophers have recently claimed not only that luck does not necessarily (...) involve a significance condition but that we should not view luck involving claims in terms of significance. After reviewing the literature on this topic, I argue that lucky events are significant. A significance condition is necessary to distinguish between different kinds of luck: practical, epistemic, and moral. All lucky events are significant and chancy, but they can be significant for subjects in different ways. For example, an event is epistemically lucky for you if it is epistemically significant and chancy, but such events need not affect your practical interests or moral standing. Furthermore, I argue that events that are chancy but not significant should be thought of in terms of chance and not luck. (shrink)

The latest book by the Slovenian critic Slavoj Zizek takes the work of French philosopher Gilles Deleuze as the beginning of a dazzling inquiry into the realms of radical politics, philosophy, film (Hitchcock, Fight Club ), and psychoanalysis. Of Organs without Bodies Joan Copjec ( Imagine There's No Woman ) has written: "With all his ususal humor and invention, Zizek -- the acknowledged master of the 180 degree turn -- here takes a trip into "enemy" territory to deliver Deleuze of (...) a marvelously rebellious child, one that seriously challenges Deleuze's other progeny with a surprising but convincing bid for succession. Those who thought Deleuze's forward march into the future would follow a straight path are forced to rethink their stance. From now on all readings of Deleuze will have to take a detour through this important -- even necessary -- book." Eric Santner ( On the Psychopathology of Everyday Life ) describes Organs without Bodies as offering "an entirely new degree of conceptual clarity and political urgency. Through his deep engagement with the logic of Deleuze's project, Zizek opens up new possibilities of thought beyond the terms of the current political debates on globalization, democratization, war on terror. Once again, Zizek has produced an utterly timely and radically untimely meditation." Recently profiled in The New Yorker , and hailed by the Village Voice as "the giant of Ljubljana," Zizek is one of the most provocative and entertaining thinkers at work today. (shrink)

The oblivion of the interval -- Being in place -- The aporia between envelope and things -- Dualism in Bergson -- Interval, sexual difference -- Beyond man: rethinking life and matter -- Conclusion: interval as relation, interval as becoming.

Luck skepticism is the view that no one is ever morally responsible for anything because of the nature and ubiquity of luck. One acclaimed argument in favor of this view is Neil Levy’s luck pincer. The luck pincer holds that all morally significant acts or events involve either present luck, constitutive luck, or both and that present and constitutive luck each negate moral responsibility. Therefore, no one is ever morally responsible for any action or event. I argue that this argument (...) is unsound as both of its premises are false. First, not all morally significant events involve present or constitutive luck. Some morally significant events are non-lucky. Second, present and constitutive luck do not always negate moral responsibility. Luck – independent of ontological concerns – is not as threatening to free will as is often thought. (shrink)

Professor Hill delivered these comments as part of the International Society for Environmental Ethics panels on Environmental Virtue Ethics, held at the annual meeting of the Pacific Division of the American Philosophical Association, April 2000, in Albuquerque, NM Philip Cafaro’s paper “Thoreau, Leopold and Carson: Toward an Environmental Virtue Ethics” appears in Environmental Ethics 23(2001), 3-17. Geoffrey Frasz’s paper “What is Environmental Virtue Ethics That We Should Be Mindful of It?” is published as part of this special issue of (...) Philosophy in the Contemporary World. (shrink)

Behavioural Network Science provides a comprehensive introduction to network science for social and behavioral researchers and students. It is a self-contained guide to the fundamentals of network science, beginning with principles of representing and making networks, network metrics, and network evolution. It then delves into specific applications of network science to behavioral research including language evolution, learning, memory, aging, creativity, conspiracies, group problem-solving, opinion polarization, and social conflict. Within each application, theoretical aspects surrounding a core problem are discussed, providing readers (...) with an intuitive understanding of how network science can be employed to quantify and generate behavioural phenomena. Accompanying online R code allows readers to replicate simulations and generate figures. This book is an essential reference for graduate students and researchers in cognitive sciences, behavioural economics, and health and social policy seeking a nuanced understanding of the intersection between network science and behavioural research. (shrink)

Abstract: Groundwork is lain for answering questions as to how to situate Husserl’s theory of functions in relation to Frege’s. I examine Husserl’s ideas about analyticity and mathematics, logic and mathematics, formalization, calculating with concepts and propositions, the foundations of arithmetic, extensions to show that, although he knew, studied and lauded Frege’s ideas about functions and concepts, each man approached the issues from different angles. Seduced by the siren of transcendental phenomenology Husserl did not pursue the issues, implications, and consequences (...) of his ideas about functions. I ask whether so doing could provide new insight into, or even solutions to, the problems involving functions that beset Frege, Russell and have beset their successors. (shrink)

With his characteristic wit, Zizek addresses the burning question of how to reformulate a leftist project in an era of global capitalism and liberal-democratic ...

Thomas E. Hill, Jr.; Servility and Self-Respect, The Monist, Volume 57, Issue 1, 1 January 1973, Pages 87–104, https://doi.org/10.5840/monist197357135.

Book synopsis: In this combative major new work, philosophical sharpshooter Slavoj Zizek looks for the kernel of truth in the totalitarian politics of the past. Examining Heidegger's seduction by fascism and Foucault's flirtation with the Iranian Revolution, he suggests that these were the 'right steps in the wrong direction.' On the revolutionary terror of Robespierre, Mao and the bolsheviks, Zizek argues that while these struggles ended in historic failure and horror, there was a valuable core of idealism lost beneath the (...) bloodshed. A redemptive vision has been obscured by the soft, decentralized politics of the liberal-democratic consensus. Faced with the coming ecological crisis, Zizekk argues the case for revolutionary terror and the dictatorship of the proletariat. A return to past ideals is needed despite the risks. In the words of Samuel Beckett: 'Try again. Fail again. Fail better.'. (shrink)