The series is devoted to the study of scientific and philosophical texts from the Classical and the Islamic world handed down in Arabic. Through critical text editions and monographs, it provides access to ancient scientific inquiry as it developed in a continuous tradition from Antiquity to the modern period. All editions are accompanied by translations and philological and explanatory notes.

A common belief is that evolution generally proceeds towards greater complexity at both the organismal and the genomic level, numerous examples of reductive evolution of parasites and symbionts notwithstanding. However, recent evolutionary reconstructions challenge this notion. Two notable examples are the reconstruction of the complex archaeal ancestor and the intron‐rich ancestor of eukaryotes. In both cases, evolution in most of the lineages was apparently dominated by extensive loss of genes and introns, respectively. These and many other cases of reductive evolution (...) are consistent with a general model composed of two distinct evolutionary phases: the short, explosive, innovation phase that leads to an abrupt increase in genome complexity, followed by a much longer reductive phase, which encompasses either a neutral ratchet of genetic material loss or adaptive genome streamlining. Quantitatively, the evolution of genomes appears to be dominated by reduction and simplification, punctuated by episodes of complexification. (shrink)

In this paper I develop three different arguments against the thesis that knowledge-how is a kind of knowledge-that. Knowledge-that is widely thought to be subject to an anti-luck condition, a justified or warranted belief condition, and a belief condition, respectively. The arguments I give suggest that if either of these standard assumptions is correct then knowledge-how is not a kind of knowledge-that. In closing I identify a possible alternative to the standard Rylean and intellectualist accounts of knowledge-how. This alternative view (...) illustrates that even if the arguments given here succeed it might still be reasonable to hold that knowing how to do something is a matter of standing in an intentional relation to a proposition other than the knowledge-that relation. (shrink)

How should intellectualists respond to apparent Gettier-style counterexamples? Stanley offers an orthodox response which rejects the claim that the subjects in such scenarios possess knowledge-how. I argue that intellectualists should embrace a revisionary response according to which knowledge-how is a distinctively practical species of knowledge-that that is compatible with Gettier-style luck.

Scale-free network models describe many natural and social phenomena. In particular, networks of interacting components of a living cell were shown to possess scale-free properties. A recent study(1) compares the system-level properties of metabolic and information networks in 43 archaeal, bacterial and eukaryal species and claims that the scale-free organization of these networks is more conserved during evolution than their content. BioEssays 24:105–109, 2002. Published 2002 Wiley Periodicals, Inc.

It is often said that ‘what it is like’-knowledge cannot be acquired by consulting testimony or reading books [Lewis 1998; Paul 2014; 2015a]. However, people also routinely consult books like What It Is Like to Go to War [Marlantes 2014], and countless ‘what it is like’ articles and youtube videos, in the apparent hope of gaining knowledge about what it is like to have experiences they have not had themselves. This article examines this puzzle and tries to solve it by (...) appealing to recent work on knowing-wh ascriptions. In closing I indicate the wider significance of these ideas by showing how they can help us to evaluate prominent arguments by Paul [2014; 2015a] concerning transformative experiences. (shrink)

In this paper, the ethical, legal, and social implications of Thailand’s surrogacy regulations from both domestic and global perspectives are explored. Surrogacy tourism in Thailand has expanded since India strengthened its visa regulations in 2012. In 2015, in the wake of a major scandal surrounding the abandonment of a surrogate child by its foreign intended parents, a law prohibiting the practice of surrogacy for commercial purposes was enacted. Consequently, a complete ban on surrogacy tourism was imposed. However, some Thai physicians (...) and surrogate mothers cross into neighboring countries to provide foreign clients with the commercial surrogacy services that are forbidden in Thailand. Under this legislation, the needs of Thai couples who are unable to conceive are accommodated by legally accessible, non-commercial surrogacy services; however, there is currently no provision in place aimed at protecting the rights and interests of surrogate mothers and children. It is widely believed that the abolition of surrogacy tourism, an industry that give rise to several major scandals, and legal access to surrogacy by Thai couples were the Thai government’s primary goal in implementing this legislation. (shrink)

This article examines the method of reflective equilibrium (RE) and its role in philosophical inquiry. It begins with an overview of RE before discussing some of the subtleties involved in its interpretation, including challenges to the standard assumption that RE is a form of coherentism. It then evaluates some of the main objections to RE, in particular, the criticism that this method generates unreasonable beliefs. It concludes by considering how RE relates to recent debates about the role of intuitions in (...) philosophy. (shrink)

Background In an increasingly globalized world, legal protocols related to health care that are both effective and culturally sensitive are paramount in providing excellent quality of care as well as protection for physicians tasked with decision making. Here, we analyze the current medicolegal status of brain death diagnosis with regard to end-of-life care in Japan, China, and South Korea from the perspectives of front-line health care workers. Main body Japan has legally wrestled with the concept of brain death for decades. (...) An inability to declare brain death without consent from family coupled with cultural expectations of family involvement in medical care is mirrored in other Confucian-based cultures and may complicate care for patients from these countries when traveling or working overseas. Within Japan, China, and South Korea, medicolegal shortcomings in the diagnosis of brain death act as a great source of stress for physicians and expose them to potential public and legal scorn. Here, we detail the medicolegal status of brain death diagnosis within Japan and compare it to China and South Korea to find common ground and elucidate the impact of legal ambiguity on health care workers. Conclusion The Confucian cultural foundation of multiple Asian countries raises common issues of family involvement with diagnosis and cultural considerations that must be met. Leveraging public education systems may increase awareness of brain death issues and lead to evolving laws that clarify such end-of-life issues while protecting physicians from sociocultural backlash. (shrink)

Previous work suggests that Asians allocate more attention to configuration information than Caucasian Americans do. Yet this cultural variation has been found only with stimuli such as natural scenes and objects that require both feature- and configuration-based processing. Here, we show that the cultural variation also exists in face perception—a domain that is typically viewed as configural in nature. When asked to identify a prototypic face for a set of disparate exemplars, Japanese were more likely than Caucasian Americans to use (...) overall resemblance rather than feature matching. Moreover, in a speeded identity-matching task, Japanese were more accurate than Americans in identifying the spatial configuration of features (e.g., eyes). Together, these findings underscore the robustness of culture’s influences on cognition. (shrink)

Surrogacy tourism in Asian countries has surged in recent decades due to affordable prices and favourable regulations. Although it has recently been banned in many countries, it is still carried out illegally across borders. With demand for surrogacy in developed countries increasing and economically vulnerable Asian women lured by lucrative compensation, there are efforts by guest countries to ease the strict surrogacy regulations in host countries. Despite a shift toward “altruistic surrogacy”, commercial surrogacy persists. Recent research carried out by international (...) organizations that seek to establish a legal relationship between the commissioning parents and children in cross-border surrogacy arrangements, under the guise of the “best interests of the child,” appears to promote a resurgence of overseas commercial surrogacy rather than restrict it. Further commercialization of surrogacy should be prevented by carefully investigating the reality of the surrogacy process. (shrink)

This chapter explores the relationship between knowing-how and skill, as well other success-in-action notions like dispositions and abilities. I offer a new view of knowledge-how which combines elements of both intellectualism and Ryleanism. According to this view, knowing how to perform an action is both a kind of knowing-that (in accord with intellectualism) and a complex multi-track dispositional state (in accord with Ryle’s view of knowing-how). I argue that this new view—what I call practical attitude intellectualism—offers an attractive set of (...) solutions to various puzzles concerning the connections between knowing-how and abilities and skills to perform intentional actions. (shrink)

Knowledge-how often appears to be more difficult to transmit by testimony than knowledge-that and knowledge-wh. Some philosophers have argued that this difference provides us with an important objection to intellectualism—the view that knowledge-how is a species of knowledge-that. This article defends intellectualism against these testimony-based objections.

Paul (2014, 2015a) argues that one cannot rationally decide whether to have a transformative experience by trying to form judgments, in advance, about (i) what it would feel like to have that experience, and (ii) the subjective value of having such an experience. The problem is if you haven’t had the experience then you cannot know what it is like, and you need to know what it is like to assess its value. However, in earlier work I argued that ‘what (...) it is like’-knowledge comes in degrees, and I briefly suggested that, consequently, some instances of Paul’s argument schema might commit a fallacy of equivocation. The aim of this paper is to further explore and strengthen this objection by, first, offering a new argument—the modelling argument—in support of it, and then by evaluating a range of replies that might be given to this objection on Paul’s behalf. I conclude that each reply either fails or, at best, only partially succeeds in defending some but not all instances of Paul’s argument schema. In closing, I consider how we might revise Paul’s concepts of transformative experiences and choices in response to this conclusion. (shrink)

What follows for the ability hypothesis reply to the knowledge argument if knowledge-how is just a form of knowledge-that? The obvious answer is that the ability hypothesis is false. For the ability hypothesis says that, when Mary sees red for the first time, Frank Jackson’s super-scientist gains only knowledge-how and not knowledge-that. In this paper I argue that this obvious answer is wrong: a version of the ability hypothesis might be true even if knowledge-how is a form of knowledge-that. To (...) establish this conclusion I utilize Jason Stanley and Timothy Williamson’s well-known account of knowledge-how as “simply a species of propositional knowledge” . I demonstrate that we can restate the core claims of the ability hypothesis – that Mary only gains new knowledge-how and not knowledge-that – within their account of knowledge-how as a species of knowledge-that. I examine the implications of this result for both critics and proponents of the ability hypothesis. (shrink)

Is there a successful regress argument against intellectualism? In this article I defend the negative answer. I begin by defending Stanley and Williamson's (2001) critique of the contemplation regress against Noë (2005). I then identify a new argument – the employment regress – that is designed to succeed where the contemplation regress fails, and which I take to be the most basic and plausible form of a regress argument against intellectualism. However, I argue that the employment regress still fails. Drawing (...) on the previous discussion, I criticise further regress arguments given by Hetherington (2006) and Noë (2005). (shrink)

This paper is a reaction to the following remark by grzegorczyk: "the compound sentences are not a product of experiment. they arise from reasoning. this concerns also negations; we see that the lemon is yellow, we do not see that it is not blue." generally, in science the truth is ascertained as indirectly as falsehood. an example: a litmus-paper is used to verify the sentence "the solution is acid." this approach gives rise to a (very intuitionistic indeed) conservative extension of (...) the heyting logic satisfying natural duality laws. (shrink)

This ambitious book looks into the reasons for the exceptional durability of the Chinese empire, which lasted for more than two millennia (221 B.C.E. - 1911 C.E.). Yuri Pines identifies the roots of the empire's longevity in the activities of thinkers of the Warring States period (453-221 B.C.E.), who, in their search for solutions to an ongoing political crisis, developed ideals, values, and perceptions that would become essential for the future imperial polity. In marked distinction to similar empires worldwide, (...) the Chinese empire was envisioned and to a certain extent 'preplanned' long before it came into being. As a result, it was not only a military and administrative construct, but also an intellectual one. Pines makes the argument that it was precisely its ideological appeal that allowed the survival and regeneration of the empire after repeated periods of turmoil. "Envisioning Eternal Empire" presents a panoptic survey of philosophical and social conflicts in Warring States political culture. By examining the extant corpus of preimperial literature, including transmitted texts and manuscripts uncovered at archaeological sites, Pines locates the common ideas of competing thinkers that underlie their ideological controversies. This bold approach allows him to transcend the once fashionable perspective of competing 'schools of thought' and show that beneath the immense pluralism of Warring States thought one may identify common ideological choices that eventually shaped traditional Chinese political culture. The result is a refreshingly novel look at the foundational period in Chinese intellectual history. (shrink)

Malignant cells are characterized by an increased content of endogenous formaldehyde formed as a by‐product of biosynthetic processes. Accumulation of formaldehyde in cancer cells is combined with activation of the processes of cellular formaldehyde clearance. These mechanisms include increased ALDH and suppressed ADH5/FDH activity, which oncologists consider poor and favorable prognostic markers, respectively. Here, the sources and regulation of formaldehyde metabolism in cancer cells are reviewed. The authors also analyze the participation of oncoproteins such as fibulins, FGFR1, HER2/neu, FBI‐1, and (...) MUC1‐C in the control of genes related to formaldehyde metabolism, suggesting the existence of two mutually exclusive processes in cancer cells: 1) production and 2) oxidation and elimination of formaldehyde from the cell. The authors hypothesize that the study of the anticancer properties of disulfiram and alpha lipoic acid – which affect the balance of formaldehyde in the body – may serve as the basis of future anticancer therapy. (shrink)

A growing literature in economics studies ethical behavior and honesty, as it is imperative for functioning societies in a world of incomplete information and contracts. A majority of studies found more pronounced dishonesty among teams compared to individuals. Scholars identified certain nudges as effective and cost-neutral measures to curb individuals' dishonesty, yet little is known about the effectiveness of such nudges for teams. We replicate a seminal nudge treatment effect, signing on the top of a reporting form vs. no signature, (...) with individuals and confirm the original nudge treatment effect. We further ran the same experiment with teams of two that have to make a joint reporting decision. Our results show the effectiveness of the nudge for teams, which provides further confidence in the applicability of the nudge. (shrink)

Background and assumptions. Persistence and philosophy of time ; Atomism and composition ; Scope ; Some matters of methodology -- Persistence, location, and multilocation in spacetime. Endurance, perdurance, exdurance : some pictures ; More pictures ; Temporal modification and the "problem of temporary intrinsics" ; Persistence, location and multilocation in generic spacetime ; An alternative classification -- Classical and relativistic spacetime. Newtonian spacetime ; Neo-Newtonian (Galilean) spacetime ; Reference frames and coordinate systems ; Galilean transformations in spacetime ; Special relativistic (...) spacetime ; Length contraction and time dilation ; Invariant properties of special relativistic spacetime -- Persisting objects in classical spacetime. Enduring, perduring, and exduring objects in Galilean spacetime ; The argument from vagueness ; From minimal D-fusions to temporal parts ; Motivating a sharp cutoff ; Some objections and replies ; Implications -- Persisting objects in Minkowski spacetime. Enduring, perduring, and exduring objects in Minkowski spacetime ; Flat and curved achronal regions in Minkowski spacetime ; Early reflections on persisting objects in Minkowski spacetime : Quine and Smart ; "Profligate ontology"? ; Is achronal universalism tenable in Minkowski spacetime? ; "Crisscrossing" and immanent causation -- Coexistence in spacetime. The notion of coexistence ; Desiderata ; Coexistence in Galilean spacetime ; Coexistence in Minkowski spacetime : CASH ; Alexandrov-Stein present and Alexandrov-Stein coexistence ; AS-Coexistence v. CASH : symmetry, multigrade, and objectivity ; As-coexistence v. CASH : relevance ; The mixed past of coexistence ; No need in the extended now -- Strange coexistence? Coexistence and existence@ ; The asymmetry thesis ; The absurdity thesis ; Collective CASH value of coexistence ; Collective existence@ and coexistence in classical spacetime ; Collective existence@ and coexistence in Minkowski spacetime ; Contextuality ; Chronological incoherence ; Some objections -- Shapes and other arrangements in Minkowski spacetime. How rigid is a granite block? ; Perspectives in space ; Perspectives in spacetime ; Are shapes intrinsic to objects? ; The causal objection ; The micro-reductive objection ; Pegs, boards, and shapes ; Perduring objects exist. (shrink)

What is the relationship between the linguistic properties of knowledge-how ascriptions and the nature of knowledge-how itself? In this chapter I address this question by examining the linguistic methodology of Stanley and Williamson (2011) and Stanley (2011a, 2011b) who defend the intellectualist view that knowledge-how is a kind of knowledge-that. My evaluation of this methodology is mixed. On the one hand, I defend Stanley and Williamson (2011) against critics who argue that the linguistic premises they appeal to—about the syntax and (...) semantics of knowledge-how and knowledge-wh ascriptions—do not establish their desired conclusions about the nature of knowledge-how itself. But, on the other hand, I also criticize the role that linguistic considerations play in Stanley’s (2011a) response to apparent Gettier-style counterexamples to intellectualism. (shrink)

A short review is given of three experimental works on tests of the Pauli Exclusion Principle (PEP) in which the author has been involved during the last 10 years. In the first work a search for anomalous carbon atoms was done and a limit on the existence of such atoms was determined, $^{12}\tilde{\mathrm{C}}$ /12C <2.5×10−12. In the second work PEP was tested with the NEMO-2 detector and the limits on the violation of PEP for p-shell nucleons in 12C were obtained. (...) Specifically, transitions to the fully occupied 1s 1/2-shell yielded a limit of 4.2×1024 y for the process with the emission of a γ-quantum. Similarly limits of 3.1×1024 y for β − and 2.6×1024 y for β + Pauli-forbidded transition of 12C → 12Ñ( $^{12}\tilde{\mathrm{B}}$ ) are reported. In the third work it was assumed that PEP is violated for neutrinos, and thus, neutrinos obey at least partly the Bose-Einstein statistics. Consequences of the violation of the exclusion principle for double beta decays were considered. This violation strongly changes the rates of the decays and modifies the energy and angular distributions of the emitted electrons. It was shown that pure bosonic neutrinos are excluded by the present experimental data. In the case of partly bosonic neutrinos the analysis of the existing data allows one to put an upper bound for sin 2 χ<0.6. The sensitivity of future measurements is also evaluated. (shrink)

Why does the ruling class in all countries of the world today act so weirdly and sometimes irresponsibly? Maybe because they are all bored. They don’t know what to do with themselves, or even what to do with their power. The deepest cause of the modern crisis is the lack of new ideas. First of all, ideas that justify your life and death. These ideas are called meanings of life, final values, final goals, final goods, human life's ends, reasons to (...) live, etc. Philosophers and psychologists pick out from five to twenty known final values that cannot be reduced to one another. The existing final values are not but the final values system itself is outdated and has not been updated for a long time. To get out of the existential crisis, we need to look for new final values. New final values mean new ethical standards, new philosophies, new religions, new ideologies, new social institutions, etc. The more final values we know, the richer our culture is, the freer we are and the more expanded (more flexible, sophisticated, etc.) our consciousness is. (shrink)

This chapter examines some key developments in discussions of the social dimensions of knowing-how, focusing on work on the social function of the concept of knowing-how, testimony, demonstrating one's knowledge to other people, and epistemic injustice. I show how a conception of knowing-how as a form of 'downstream knowledge' can help to unify various phenomena discussed within this literature, and I also consider how these ideas might connect with issues concerning wisdom, moral knowledge, and moral testimony.