The aim of the experiment was to evaluate the adaptive responses of biomechanical and electromyographic parameters to vertical unloading when walking during the 4-month isolation experiment SIRIUS-19 in the ground-based space station model. The study involved 6 healthy international crew members of the SIRIUS-19 project aged 34 ± 6.2 years. Body Weight Unloading conditions was created by the h/p/cosmos airwalk system. The locomotor test included walking with a sequential change of BWU modes: 5-min walking with 0% BWU, 5-min walking with (...) 65% BWU and 5-min walking with 85% BWU. Ground Reaction Force was recorded by the h/p/cosmos treadmill device. Muscle Lab Model 4000e device was used to record the electromyographic signals of the hip and shin muscles. The locomotor test was performed twice before GBI, monthly during GBI and 1 week after leaving isolation. The results obtained before GBI demonstrate that the changes of support and proprioceptive afferentation signals play significant role in reorganizing of the biomechanical structure of motor acts and the development of new movement patterns. The results of the study are consistent with the previously obtained results of other studies in this direction. Despite the fact that during the GBI the participants of the experiment performed regular physical training, a decrease in the performance indicators values was detected, especially pronounced after 100 days of GBI. This is probably due to limited space of a space station model, as well as the development of a special motor stereotype in it. Noteworthy are the results obtained after the 4th session of the experiment, indicating the effect of sensorimotor learning. We think that the data obtained in this study will be useful in research both in gravitational physiology and in clinical medicine. (shrink)

The paper focuses on the review of current literature on formal philosophy. Special attention is paid to the review of the book «Introduction to Formal Philosophy» [Hansson, Hendricks, 2018]. The book is a consistent introduction to the problems of formal philosophy, a research tradition that relies on the precise mathematical tools in order to study traditional philosophical problems. The methods of formal philosophy are successfully applied not only to the problems of ontology, epistemology and philosophy of language but also relevant (...) for the problems of ethics, axiology and social philosophy. The book demonstrates that it is not correct to identify formal philosophy with another area of study – philosophical logic, since formal philosophy uses not only logical methods of analysis, but also uses the tools of game theory, decision theory, probability theory, Bayesian statistics, and other theories. Although the book has a propaedeutic character, it also contains some open problems. These problems include the aggregation of the opinions of the group under the condition of a conflicting base of premises in the theory of public choice, there are still open problems in the interpretation of Arrow’s impossibility theorem and others. Certainly, formalization in itself is not a general solution to the particular philosophical problem, but only a tool that allows to formulate a problem in a more rigorous and precise way, which sometimes allows to reveal some unexpected consequences, some implicit contradictions and new solutions. Despite the importance of the concept of coherence in ethics, decision theory, philosophy of law, Bayesian epistemology, philosophy of science, the existing formalizations of the concept of coherence are highly specialized for epistemology, researchers recognize the lack of the relevant explanatory models. Overall, the book is an excellent introduction in to the field of formal philosophy, which provides a general overview of different aspects of formal philosophy and the opportunity to study particular research topics by means of an extensive bibliography accompanying each of the chapters. (shrink)

In addition to their function in transport of water, ions, small metabolites, and growth factors in normal plant tissue, the plasmodesmata presumably serve as routes for cell‐to‐cell movement of plant viruses in infected tissue. Virus cell‐to‐cell spread through plasmodesmata is an active process mediated by specialized virus encoded movement proteins; however, the mechanism by which these proteins operate is not clear. We incorporate recent information on the biochemical properties of plant virus movement proteins and their interaction with plasmodesmata in a (...) model for transport of nucleic acids through plasmodesmatal channels. We propose that only single stranded (ss) nucleic acids can be transported efficiently through plasmodesmata, and that movement proteins function as molecular chaperones for ss nucleic acids to form unfolded movement protein‐ss nucleic acid complexes. These complexes are targeted to plasmodesmata. Plasmodesmatal permeability is then increased following interaction with movement protein and the entire movement complex or its nucleic acid component is translocated across the plasmodesmatal channel. (shrink)

This paper presents the contributions of the French Dominican priest Louis-Joseph Lebret to the emergence of development ethics. Starting from his life and experiences, it outlines his concept of d...

Sargonic Cuneiform Tablets in the Real Academia de la Historia: The Carl L. Lippmann Collection. By Manuel Molina. Catálogo del Gabinete de Antigüedades. Madrid: Real Academia de la Historia and Ministerio de Cultura de la República de Iraq, 2014. Pp. 317, 337 plts.

Wissenskultur im Alten Orient: Weltanschauung, Wissenschaften, Techniken, Technologien. Edited by Hans Neumann. Colloquien der Deutschen Orient-Gesellschaft, vol. 4. Wiesbaden: Harrassowitz Verlag, 2012. Pp. xi + 433, illus. €42.

In spite of all the industrious efforts Peirce scholars have made so far, Peirce’s biography still retains a number of gaps, among which the problem of identity of Peirce’s second wife, Juliette Froissy, stands out most significantly. It is all the more important that, as some scholars suggest, the discovery of any reliable facts about Juliette could provide an explanation to some of the decisions Peirce had made, which irrevocably changed the course of his life, as well as his semiotic (...) theory. By courtesy of Professor Dr. Nathan Houser and the Peirce Edition Project, the writer of the present paper was granted access to the archive materials containing the Max H. Fisch — Maurice Auger correspondence and Victor Lenzen’s notes on Juliette. The paper aims at arranging the dispersed data obtained from these and other sources into a set of several distinct versions, which curiously refer to each other and collectively impose a certain order on some major abductions concerning Juliette’s identity. (shrink)

This article explores contemporary approaches to the understanding and interpretation of the formation of inclusive society. The focus is on the investigation of the everyday experiences of individuals who face various limitations in their living conditions such as limited opportunities, special needs, and disabilities. The paper highlights the importance of considering the unique aspects of subjective time when systematically analyzing the functional characteristics and existential mechanisms of an inclusive society, which constitutes the living environment for people with disabilities. It points (...) out that the temporal intentionality of a mentally challenged individual manifests in a unique form of ordering, synchronization, and existence within various phenomena and events within the individual's mental imagery and inner experiences. The authors emphasize the necessity to differentiate two primary stages in an individual's perception and understanding of their actual existence—the evaluation stage and the stage of identifying prospects. The study shows how intentional temporality inherently transforms into individual time, revealing the peculiarities of internal experiences and the unique aspects of an individual's mental imagery. These are integral steps in the formation of a system of social events that are marked within the individual consciousness. The novelty of this study lies in the examination of intentionality within the framework of a disabled person's subjective time, a characteristic that is fundamentally individual yet resonates with the collective daily consciousness of disabled individuals within an inclusive micro-society. (shrink)

The article provides a brief overview of the philosophical and methodological problems of modern collaborative research. Collaborations – distributed organizations with variable membership, consisting of a large number (sometimes several thousand) of participants – are common in experimental high-energy physics studying microcosm objects, elementary particles arising in collisions of beams of accelerated particles and nuclei at collider accelerators, as well as in biomedicine and climatology. The central issues are authorship, epistemic ownership and dependence in collaborations, the division of epistemic labor (...) in interdisciplinary research, as well as related issues of scientific organization – peer review and distribution of credit in a team. Formally, the author, conceived as a list of persons appearing as authors of a collaborative scientific work, seems to be defined by the specific participants of the collaboration core, i.e., is a construct. However, the question can also be understood as “What does it mean to be the author of a scientific work?”, and then the answer becomes much less certain. Authorship of thousand-people articles is justified psychologically as the desire for regular performance of a ritual, which allows demonstrating joint belonging to a certain tradition, such as a long experiment, affiliation with the “workshop” of scientists studying phenomena of the microworld, which allows scientists, despite of their daily preoccupation with technical routines, to distinguish themselves from non-epistemic communities (engineers, technicians). However, specific rules that determine exactly who and why are worthy of being included as co-authors have been undergoing changes in recent years. In addition to theoretical significance, many of the problems discussed are related to actual practical issues of scientometry and the organization of scientific research, and therefore approaches to their solution can be directly embodied in scientific policy. (shrink)

Verification and validation of computer codes and models used in simulations are two aspects of the scientific practice of high importance that recently have been discussed widely by philosophers of science. While verification is predominantly associated with the correctness of the way a model is represented by a computer code or algorithm, validation more often refers to the model’s relation to the real world and its intended use. Because complex simulations are generally opaque to a practitioner, the Duhem problem can (...) arise with verification and validation due to their entanglement; such an entanglement makes it impossible to distinguish whether a coding error or the model’s general inadequacy to its target should be blamed in the case of a failure. I argue that a clear distinction between computer modeling and simulation has to be made to disentangle verification and validation. Drawing on that distinction, I suggest to associate modeling with verification and simulation, which shares common epistemic strategies with experimentation, with validation. To explain the reasons for their entanglement in practice, I propose a Weberian ideal–typical model of modeling and simulation as roles in practice. I examine an approach to mitigate the Duhem problem for verification and validation that is generally applicable in practice and is based on differences in epistemic strategies and scopes. Based on this analysis, I suggest two strategies to increase the reliability of simulation results, namely, avoiding alterations of verified models at the validation stage as well as performing simulations of the same target system using two or more different models. In response to Winsberg’s claim that verification and validation are entangled I argue that deploying the methodology proposed in this work it is possible to mitigate inseparability of V&V in many if not all domains where modeling and simulation are used. (shrink)

Since the seminal paper of Nash (Proc Natl Acad Sci USA 36:48–49, 1950) game theoretic literature has focused mostly on equilibrium and not on maximin (minimax) strategies. In a recent paper of Pruzhansky (Int J Game Theory 40:351–365, 2011) it was shown that under fairy general conditions maximin strategies in completely mixed games can guarantee the same expected payoff as completely mixed Nash equilibrium strategies. Based on this finding, the current paper argues that maximin strategies have important properties. For instance, (...) maximin strategies may refine Nash equilibria in subjective mixed strategies. Further, Bayesian rationality of the players may favor maximin strategies more often than Nash equilibrium strategies. The paper concludes with several suggestions for further experimental research that may shed more light on whether maximin behavior can explain reality better than Nash equilibrium. (shrink)

The article presents a careful analysis of the idea of the “open texture” of empirical concepts and the problems of verification in the way that they were formulated by Friedrich Waismann. The idea of the “open texture” means for Waismann a certain type of a linguistic indeterminacy or a sort of lack of definition, which must be distinguished from, and linked to, another types like vagueness or ambiguity. It is shown that empirical statements are not conclusively verifiable for two different (...) reasons: the incompleteness of description of the material object and the open texture of the terms involved. We cannot conclusively verify statements in which the empirical concepts are used, because we cannot define these concepts in an exhaustive way because of their open texture. Thus, the definition of the concept will be incomplete. Waismann’s approach to definition plays here a key role, and it is directly related to the open texture of concepts. The author proposes interpreting the open texture as an immanent property of the concept, as something that is embedded in it a priori, and which can cause a vagueness. Nevertheless, an open texture must be distinguished form a vagueness. This leads to the conclusion that an open texture is a possibility of vagueness; vagueness can be remedied by giving more accurate rules, open texture cannot. In this sense, the “open texture” of a language allows for a more precise definition of concepts (by adjusting the definition) if appropriate circumstances arise. This justifies the thesis that the argument of the open texture is the ontological basis of the linguistic anti-reductionism of Friedrich Waismann. (shrink)

The relationship between logic and ethics is one of the basic and most essential questions of classical philosophical analysis. Since the time of the Pythagoreans, the fundamental unity of the two – whether by means of vague intuition, an elaborate conceptual scheme, or even a carefully crafted lifestyle – has led philosophers to identify truth and virtue. In his critical philosophy Kant put this unity of truth and virtue to extensive and rigorous trial to determine what conditions, if any, a...

InMind and World,John McDowell claims that we need to steer our way between bald naturalism and rampant platonism as two ways to explain our capacity to use concepts. Performing this task requires an explanation of how concepts can be both socially charged and, at the same time, genuinely involving the world as it really is. I suggest that McDowell’s explanation is insufficient and that Wilfrid Sellars’s idea of sense impressions might be used to clarify the relationship between social practices and (...) conceptual knowledge without incurring too much damage to the overall architectonics of McDowell’s theory.DansMind and World, John McDowell affirme que nous devons nous éloigner du naturalisme dépouillé et du platonisme exubérant comme étant deux manières d’expliquer notre capacité à utiliser des concepts. Pour accomplir cette tâche, il est nécessaire d’expliquer comment les concepts peuvent être à la fois chargés socialement et réellement engagés avec le monde tel qu’il est. Je suggère que l’explication de McDowell est insuffisante et que l’idée de Wilfrid Sellars des impressions sensorielles peut être utilisée pour clarifier la relation entre les pratiques sociales et la connaissance conceptuelle, et ceci sans faire encourir trop de dégâts à l’architectonique générale de la théorie de McDowell. (shrink)

The era of the Tang dynasty was a period of great flourishing of all aspects of Chinese culture, when changes covered the most diverse spheres of philosophy, art and literature. The article examines the role played in this cultural transformation by translations from Sanskrit into Chinese of the religious and philosophical texts of Indian Buddhism. The specificity of the Chinese approach to the translation of Indian texts is demonstrated, when, at the initial stage, many works were translated in a rather (...) free style due to the lack of precisely established correspondences between Sanskrit and Chinese philosophical terms. The authors identify two additional factors that influenced the nature of the translations. Firstly, this is the requirement of compliance with the norms of public, mainly Confucian, morality. Secondly, the adaptation of the Indian philosophical context to the Chinese cultural and worldview traditions, which led to the emergence of new schools of religious and philosophical thought that were not known in India itself, such as Tiantai, Jingtu or Chan, each of which in its own way influenced the art of the Medieval China. Special attention is paid to the activities of the legendary translator, Xuanzang, whose travel to India gave a huge impetus to the development of Chinese philosophy in subsequent centuries, as well as to the contribution to Chinese culture and art, which was made by the translation activities of the three great teachers of the Tang era Shubhakarasimha, Vajrabodhi and Amoghavajra. (shrink)

In The Sources of Normativity Korsgaard introduces her conception of practical identities understood as the source of moral obligations. This conception forms a point of transition from Korsgaard’s theory of action to her solution to the problem of the authority of moral norms. In order to describe how universal categorical reasoning is compatible with the moral content of particular practical decisions, Korsgaard needs to show how our contingent practical identities can be reconciled with what she defines as the universally shared (...) identity that expresses our humanity. To make this reconciliation work, she devises an argument for the public shareability of reasons amended by her reinterpretation of the Kantian as if principle. I suggest that, in doing so, Korsgaard steps too far away from Kant’s architectonic approach to the question of why moral norms bind us, and that, consequently, the Korsgaardian reconciliation between the two kinds of identities, as it stands, cannot be accomplished. (shrink)

This book is about the relationship between necessary reasoning and visual experience in Charles S. Peirce’s mathematical philosophy. It presents mathematics as a science that presupposes a special imaginative connection between our responsiveness to reasons and our most fundamental perceptual intuitions about space and time. Central to this view on the nature of mathematics is Peirce’s idea of diagrammatic reasoning. In practicing this kind of reasoning, one treats diagrams not simply as external auxiliary tools, but rather as immediate visualizations of (...) the very process of the reasoning itself. Thus conceived, one's capacity to diagram their thought reveals a set of characteristics common to ordinary language, visual perception, and necessary mathematical reasoning. The book offers an original synthetic approach that allows tracing the roots of Peirce’s conception of a diagram in certain patterns of interrelation between his semiotics, his pragmaticist philosophy, his logical and mathematical ideas, bits and pieces of his biography, his personal intellectual predispositions, and his scientific practice as an applied mathematician. (shrink)

The conception of two kinds of practical identities, which Korsgaard introduces in the Sources of Normativity, helps her explain how universal categorical reasoning is compatible with the moral content of individual practical decisions. Based on this conception, she devises an interpretation of the Kantian as if principle amended by her argument for the public shareability of reasons. I suggest that, in doing so, Korsgaard steps too far away from Kant’s architectonic approach to the question of why moral norms bind us, (...) and that, as a result, the Korsgaardian explanation, as it stands, cannot be accomplished. (shrink)

This paper compares Charles Peirce’s and Robert Brandom’s conceptions of normative objectivity. According to Brandom, discursive norms are instituted by practical attitudes of the members of a community, and yet the objectivity of these norms is not reducible to social consensus. Peirce’s conception of normative objectivity, on the contrary, is rooted in his idea of a community of inquiry, which presupposes a consensus achievable in the long run. The central challenge in both cases is to explain how the norms that (...) all members of a community take to be correct differ from those that are correct objectively. I argue that, in meeting the challenge of reconciling the social character of knowledge and the objectivity of norms shared by a community of knowers, Brandom’s approach might benefit from the Peircean idea of the ultimate agreement. (shrink)

The present paper is aimed at showing some correlations between Charles Peirce’s life, his intellectual habits as a logician and mathematician, his semiotic theory and his practice as a geodesist. For this purpose, it makes use of Peirce’s ideas about the nature of visual experience, some facts of his intellectual biography, and his definitions of sign and the term “virtual.” It appears that Peirce’s mature pragmatist and semiotic ideas find some support in his early practice as a scientist and a (...) mathematician, thus providing an interesting example of the intersection of scientific practice and philosophical speculation. (shrink)

The article presents a detailed consideration of the arguments from the symposium “Verifiability”, which was held on July 14, 1945 in London, proposed by Scottish philosopher and theologian Donald MacKinnon, Austrian logician and mathematician Friedrich Waismann and English logician and philosopher of science William Kneale. MacKinnon’s approach to verifiability was based on the metaphysics of fact, while Waismann and Kneale’s approach was based on the semantic specificity of empirical concepts (“open texture” and context of use) and on the truth-values of (...) empirical propositions. The symposium in question is interesting primarily because it is the last meaningful discussion on the concept of verifiability in the form in which it was understood by the Vienna Circle. Despite the fact that, in the coming years, this concept received a completely different interpretation, which stands away from the original source, the 1945 symposium could be rightfully treated as a canonical discussion on verifiability in the sense that nothing like this has ever happened in the philosophy after. (shrink)

The article presents the philosophical and linguistic conception of Friedrich Waismann – the theory of many-level-structure of language. The key point of this theory is that each language stratum has its own logic: different concepts of truth, the methods of verifiability and the completeness of description are used in different strata. All this has an influence on the structure of logic itself. This approach suggests that all homogeneous statements (identical in a logical sense) are grouped in one stratum. The relations (...) between the different strata are of a most complicated, peculiar and elusive nature and that does not allow to reduce statement of one stratum to another. According to Waismann, these considerations lead to a new picture of the language, naturally divided into strata. (shrink)

The appearance in 1945 of the idea of the open texture of empirical concepts, which anticipated Friedrich Waismann’s thesis of a many-level-structure of language, led to a re-evaluation of “context”. It widens the sense of context that we are accustomed to mentioning as being Wittgenstein’s conception of meaning in his later philosophy. The new idea Waismann brought into the landscape is how to “clarify the context”, which is in a way a very non-Wittgensteinian question as well as an “explanation of (...) context”, where open texture plays a key role. But despite the amount of literature about open texture, this idea of Waismann is still not properly understood. Open texture must be situated as an obstacle to exhaustiveness of definition for internal reasons not only because of unforeseen conditions that could always arise in the future, but also by virtue of an a priori aspect of the texture of concepts. Thus, the main goal of this paper is to propose an interpretation of open texture as an immanent property of a concept, that is, as something that is underlying its nature. (shrink)

The article examines K.A. Rodin’s thesis on the possibility of including Wittgenstein’s remarks on intention and action in the context of legal philosophy research. It is shown that although the concepts of intention and intentional action are relevant to the philosophy of law, Wittgenstein’s own ideas did not have a significant impact on their relevance (and some of them did not have it at all). This influence is confined to the fact that, like Wittgenstein, many jurists and legal theorists, mainly (...) those who were influenced by the ideas of H.L.A. Hart, also objected to the causal theory of action. However, the influence is limited to this approach. (shrink)

The paper investigates the way in which criminal law of most countries allocates to the idea of intention, as one of the principal determinants of liability to punishment. All civilized penal systems make liability to punishment for at any rate serious crime dependent not merely on the fact that the person to be punished has done the outward act of a crime, but on his having done it in a certain state of frame of mind. These mental or intellectual elements (...) are many and various andare collected together in the legal terminology under the description of a guilty mind. But the most prominent, of these mental elements, and in many ways the most important, is a man's intention. The law's concern with intention generates a number of problems, some of which are discussed in this paper. It is argued that even before one reaches these problems there is a more fundamental question to be addressed: what is a man's intention? This is a question which, quite apart from the law, philosophers have found both intriguing and difficult to answer. The author discusses howit can add complexity to what is considered intentional in criminal law. (shrink)

During its hundred-year history, Ludwig Wittgenstein’s Tractatus Logico-Philosophicus has undergone a variety of interpretations and explanations. But the significance of this work cannot be limited to an assessment of whether it had an impact on the development of logical positivism or not. Similarly, the reading of Tractatus cannot be reduced to just an ethical or some other readings. This article proposes to study a possible reading of “Tractatus” in terms of legal philosophy, which is based on the relation between facts, (...) values and norms, as well as on how interesting it could be (or would be) for legal philosophy. (shrink)

The Constitution is considered as an informal axiomatic system. The strategy proposed by the authors rests on the following propositions: axioms are considered as contextual definitions of those concepts by means of which they are formulated; and the main requirement for this type of system is internal consistency. The first proposition is necessary for considering the Constitution as an informal axiomatic system, while the second is sufficient, because the approach proposed, apart from consistency, must certainly consider the requirements for formal (...) axiomatic systems, such as independence and completeness. The authors argue that the Constitution can be compared to axiomatic constructions in modern science in the sense that is given in the research on the logic and methodology of deductive sciences. This analogy is appropriate to the extent to which constitutional provisions are interpreted as the basic elements of the legal system, just as in the formal sciences axioms are regarded as basic principles that define the main features of the formal system. This means that the Constitution itself is seen as coherent, consistent discourse that contextually defines the meaning of the basic terms of the legal system. (shrink)

[full article, abstract in English; only abstract in Lithuanian] This paper proposes a new pragmatic interpretation of the Frege–Geach problem and presents a possible solution using a model of ascriptive legal language. The first section includes the definition of the Frege–Geach problem. In the second section, I analyze the content of Geach’s critical argument against prescriptivism in ethics. I discuss what Geach means by ascriptivism, why he mixes it with prescriptivism, and why a particular article by Herbert Hart became the (...) subject of criticism by Geach. The third section proposes a possible solution to the Frege–Geach problem based on the explication of the assertoric force of ascriptive legal utterances and the performativity of legal language. (shrink)

The article presents an analysis of K.A. Rodin’s argument that after publishing of Peter Winch’s book “The Idea of Social Science” (1958) the discussions of rule-following problem concerning to social epistemology and the methodology of social studies have not had tangible results. It is shown by the example of modern legal studies that this conclusion is not valid. On the contrary, Wittgenstein’s problem of rule-following and the very idea of rule-shaped activity have proved to have a great importance for an (...) analytical legal philosophy and turned into an independent subject of study. (shrink)