In recent years, the publication of the studies on the transmissibility in mammals of the H5N1 influenza virus and synthetic genomes has triggered heated and concerned debate within the community of scientists on biological dual-use research; these papers have raised the awareness that, in some cases, fundamental research could be directed to harmful experiments, with the purpose of developing a weapon that could be used by a bioterrorist. Here is presented an overview regarding the dual-use concept and its related international (...) agreements which underlines the work of the Australia Group Export Control Regime. It is hoped that the principles and activities of the AG, that focuses on export control of chemical and biological dual-use materials, will spread and become well known to academic researchers in different countries, as they exchange biological materials and scientific papers. To this extent, and with the aim of drawing the attention of the scientific community that works with yeast to the so called Dual-Use Research of Concern, this article reports case studies on biological dual-use research and discusses a synthetic biology applied to the yeast Saccharomyces cerevisiae, namely the construction of the first eukaryotic synthetic chromosome of yeast and the use of yeast cells as a factory to produce opiates. Since this organism is considered harmless and is not included in any list of biological agents, yeast researchers should take simple actions in the future to avoid the sharing of strains and advanced technology with suspicious individuals. (shrink)

Introduction: bearing politics -- Abortion, sin, and the state -- A history of the abortion debate -- Conceiving the nation: representations of abortion in Thailand -- Corrupt girls, victims of men, desperate women: representations of women who abort -- 'A small sin': everyday acts -- 'The truth of our day by day lives': situational ethics -- Global debates, local dilemmas.

Originally presented as the author's thesis (doctoral--Gregorian University).

The present study investigates the types of verb and symbolic representational strategies used by 10 deaf signing adults and 13 deaf signing children who described in Italian Sign Language 45 video clips representing nine action types generally communicated by five general verbs in spoken Italian. General verbs, in which the same sign was produced to refer to several different physical action types, were rarely used by either group of participants. Both signing children and adults usually produced specific depicting predicates by (...) incorporating, through a representational strategy, the object and/or the modality of the action into the sign. As for the different types of representational strategies, the adults used the hand-as-object strategy more frequently than the children, who, in turn, preferred to use the hand-as-hand strategy, suggesting that different degrees of cognitive complexity are involved in these two symbolic strategies. Addressing the symbolic iconic strategies underlying sign formation could provide new insight into the perceptual and cognitive processes of linguistic meaning construction. The findings reported here support two main assumptions of cognitive linguistics applied to sign languages: there is a strong continuity between gestures and language; lexical units and depicting constructions derive from the same iconic core mechanism of sign creation. (shrink)

Accompanying DVD is a filmed segment of the conversation.

Friedrich Nietzsche in seinen Werken ist ein unveränderter, hochwertiger Nachdruck der Originalausgabe aus dem Jahr 1894. Hansebooks ist Herausgeber von Literatur zu unterschiedlichen Themengebieten wie Forschung und Wissenschaft, Reisen und Expeditionen, Kochen und Ernährung, Medizin und weiteren Genres. Der Schwerpunkt des Verlages liegt auf dem Erhalt historischer Literatur. Viele Werke historischer Schriftsteller und Wissenschaftler sind heute nur noch als Antiquitäten erhältlich. Hansebooks verlegt diese Bücher neu und trägt damit zum Erhalt selten gewordener Literatur und historischem Wissen auch für die Zukunft (...) bei. (shrink)

Entailment relations, introduced by Scott in the early 1970s, provide an abstract generalisation of Gentzen’s multi-conclusion logical inference. Originally applied to the study of multi-valued logics, this notion has then found plenty of applications, ranging from computer science to abstract algebra. In particular, an entailment relation can be regarded as a constructive presentation of a distributive lattice and in this guise it has proven to be a useful tool for the constructive reformulation of several classical theorems in commutative algebra. In (...) this paper, motivated by these concrete applications, we state and prove a cut-elimination result for inductively generated entailment relations. We analyse some of its consequences and describe the existing connections with analogous results in the literature. (shrink)

Although mouse‐tracking has been taken as a real‐time window on different aspects of human decision‐making processes, whether purely semantic information affects response conflict at the level of motor output as measured through mouse movements is still unknown. Here, across two experiments, we investigated the effects of semantic knowledge by predicting participants’ performance in a standard keyboard task and in a mouse‐tracking task through distributional semantics, a usage‐based modeling approach to meaning. In Experiment 1, participants were shown word pairs and were (...) required to perform a two‐alternative forced choice task selecting either the more abstract or the more concrete word, using standard keyboard presses. In Experiment 2, participants performed the same task, yet this time response selection was achieved by moving the computer mouse. Results showed that the involvement of semantic components in the task at hand is observable using both standard reaction times (Experiment 1) as well as using indexes extracted from mouse trajectories (Experiment 2). In particular, mouse trajectories reflected the response conflict and its temporal evolution, with a larger deviation for increasing word semantic relatedness. These findings support the validity of mouse‐tracking as a method to detect deep and implicit decision‐making features. Additionally, by demonstrating that a usage‐based model of meaning can account for the different degrees of cognitive conflict associated with task achievement, these findings testify the impact of the human semantic memory on decision‐making processes. (shrink)

Recent research put forward the hypothesis that eye movements are integrated in memory representations and are reactivated when later recalled. However, “looking back to nothing” during recall might be a consequence of spatial memory retrieval. Here, we aimed at distinguishing between the effect of spatial and oculomotor information on perceptual memory. Participants’ task was to judge whether a morph looked rather like the first or second previously presented face. Crucially, faces and morphs were presented in a way that the morph (...) reactivated oculomotor and/or spatial information associated with one of the previously encoded faces. Perceptual face memory was largely influenced by these manipulations. We considered a simple computational model with an excellent match that expresses these biases as a linear combination of recency, saccade, and location. Surprisingly, saccades did not play a role. The results suggest that spatial and temporal rather than oculomotor information biases perceptual face memory. (shrink)

Theories of binding have recently come into the focus of the consciousness debate. In this review, we discuss the potential relevance of temporal binding mechanisms for sensory awareness. Specifically, we suggest that neural synchrony with a precision in the millisecond range may be crucial for conscious processing, and may be involved in arousal, perceptual integration, attentional selection and working memory. Recent evidence from both animal and human studies demonstrates that specific changes in neuronal synchrony occur during all of these processes (...) and that they are distinguished by the emergence of fast oscillations with frequencies in the gamma-range. (shrink)

Die Reihe Beihefte zur Zeitschrift für die neutestamentliche Wissenschaft (BZNW) ist eine der ältesten undrenommiertesten internationalen Buchreihen zur neutestamentlichen Wissenschaft. Seit 1923 publiziert sie wegweisende Forschungsarbeiten zum frühen Christentum und angrenzenden Themengebieten. Die Reihe ist historisch-kritisch verankert und steht neuen methodischen Ansätzen, die unser Verständnis des Neuen Testaments befördern, gleichfalls offen gegenüber.

We review major developmental evidence on the continuity from action to gesture to word and sign in human children, highlighting the important role of caregivers in the development of multimodal communication. In particular, the basic issues considered here and contributing to the current debate on the origins and development of the language-ready brain are: (1) links between early actions, gestures and words and similarities in representational strategies; (2) importance of multimodal communication and the interplay between gestures and spoken words; (3) (...) interconnections between early actions, gestures and signs. The innovation of this report is in connecting these themes together to relevant findings from studies on children between 6 and 36 months of age and highlighting interesting parallels in studies on ape communicative behavior. (shrink)

So‐called nudge policies utilize insights from behavioral science to achieve policy outcomes. Nudge policies try to improve people's decisions by changing the ways options are presented to them, rather than changing the options themselves or incentivizing or coercing people. Nudging has been met with great enthusiasm but also fierce criticism. This paper provides an overview of the debate on the ethics of nudging to date. After outlining arguments in favor of nudging, we first discuss different objections that all revolve around (...) the worry that nudging vitiates personal autonomy. We split up this worry into different dimensions of autonomy, such as freedom of choice, volitional autonomy, rational agency, and freedom as nondomination. We next discuss worries that nudging is manipulative, violates human dignity, and prevents more important structural reform. Throughout, we will present responses that proponents of nudging can muster. On the whole, we conclude that the objections fail to establish that the nudge program as a whole should be rejected. At the same time, they give us important guidance when moving towards an ethical assessment of nudges on a case‐by‐case basis. Towards the end, we provide some possible ways forward in debates around the ethics of nudging. (shrink)

In this book, the contributors expand on their use of Mayes archetypal pedagogy in volume 1 to apply its principles to a wide variety of venues, purposes, and projects. Each essay explores from its own disciplinary angle the difference between what Mayes has called "educational processes" (which are those practices that take place in the dedicated space of the classroom, through the medium of the curriculum, and under the stewardship of the teacher) and "educative acts" (which are those deep transactions (...) between individuals in joint pursuit of existential truth, wherein one is alternately the teacher and student in conversation, and sometimes even communion, with one's dialogical partner"). (shrink)

Cognitive science is experiencing a pragmatic turn away from the traditional representation-centered framework toward a view that focuses on understanding cognition as "enactive." This enactive view holds that cognition does not produce models of the world but rather subserves action as it is grounded in sensorimotor skills. In this volume, experts from cognitive science, neuroscience, psychology, robotics, and philosophy of mind assess the foundations and implications of a novel action-oriented view of cognition. Their contributions and supporting experimental evidence show that (...) an enactive approach to cognitive science enables strong conceptual advances, and the chapters explore key concepts for this new model of cognition. The contributors discuss the implications of an enactive approach for cognitive development; action-oriented models of cognitive processing; action-oriented understandings of consciousness and experience; and the accompanying paradigm shifts in the fields of philosophy, brain science, robotics, and psychology. ContributorsMoshe Bar, Lawrence W. Barsalov, Olaf Blanke, Jeannette Bohg, Martin V. Butz, Peter F. Dominey, Andreas K. Engel, Judith M. Ford, Karl J. Friston, Chris D. Frith, Shaun Gallagher, Antonia Hamilton, Tobias Heed, Cecilia Heyes, Elisabeth Hill, Matej Hoffmann, Jakob Hohwy, Bernhard Hommel, Atsushi Iriki, Pierre Jacob, Henrik Jörntell, Jürgen Jost, James Kilner, Günther Knoblich, Peter König, Danica Kragic, Miriam Kyselo, Alexander Maye, Marek McGann, Richard Menary, Thomas Metzinger, Ezequiel Morsella, Saskia Nagel, Kevin J. O'Regan, Pierre-Yves Oudeyer, Giovanni Pezzulo, Tony J. Prescott, Wolfgang Prinz, Friedemann Pulvermüller, Robert Rupert, Marti Sanchez-Fibla, Andrew Schwartz, Anil K. Seth, Vicky Southgate, Antonella Tramacere, John K. Tsotsos, Paul F. M. J. Verschure, Gabriella Vigliocco, Gottfried Vosgerau. (shrink)

L'ingegneria concettuale è una branca della filosofia caratterizzata da un approccio normativo nei confronti della rappresentazione. Assunzione fondamentale è che i nostri dispositivi rappresentazionali possano essere difettosi. Si configura dunque come l'attività che consiste nell'identificare i difetti in tali dispositivi e mettere in atto strategie di miglioramento. Verranno illustrate le questioni fondamentali a cui una teoria di ingegneria concettuale deve rispondere: in cosa consiste esattamente questa attività? Come possiamo attuarla? Quali meccanismi regolano la formazione dei dispositivi rappresentazionali? Possiamo influire su (...) tali meccanismi? Verrà inoltre presentata un'obiezione all'ingegneria concettuale e varie risposte. -/- Conceptual engineering is a branch of philosophy characterised by a normative approach towards representation. The fundamental assumption of it is that our representational devices can be defective. Conceptual engineering is then the activity consisting of identifying the defects of such devices and putting in place ameliorative strategies. This paper illustrates the fundamental issues for a theory of conceptual engineering: what does this activity consist of? How can we implement it? What mechanisms regulate the formation of representational devices? Can we have an influence over those mechanisms? Moreover, it will be presented an objection to conceptual engineering and various responses to it. (shrink)

Andreas Stokke presents a comprehensive study of lying and insincere language use. He investigates how lying relates to other forms of insincerity and explores the kinds of attitudes that go with insincere uses of language. -/- Part I develops an account of insincerity as a linguistic phenomenon. Stokke provides a detailed theory of the distinction between lying and speaking insincerely, and accounts for the relationship between lying and deceiving. A novel framework of assertion underpins the analysis of various kinds of (...) insincere speech, including false implicature and forms of misleading with presuppositions, prosodic focus, and semantic incompleteness. -/- Part II sets out the relationship between what is communicated and the speaker's attitudes. Stokke develops the view of insincerity as a shallow phenomenon that is dependent on conscious attitudes rather than deeper motivations. The various of ways of speaking while being indifferent toward what one communicates are covered, and the phenomenon of 'bullshitting' is distinguished from lying and other forms of insincerity. Finally, an account of insincere uses of interrogative, imperative, and exclamative utterances is also given. (shrink)

Many of our endeavors -- be it personal or communal, technological or artistic -- aim at eradicating all traces of dissatisfaction from our daily lives. They seek to cure us of our discontent in order to deliver us a fuller and flourishing existence. But what if ubiquitous pleasure and instant fulfilment make our lives worse, not better? What if discontent isn't an obstacle to the good life but one of its essential ingredients? In Propelled, Andreas Elpidorou makes a lively case (...) for the value of discontent and illustrates how boredom, frustration, and anticipation are good for us. Weaving together stories from sources as wide-ranging as classical literature, social and cognitive psychology, philosophy, art, and video games, Elpidorou shows that these psychological states aren't unpleasant accidents of our lives. Rather, they illuminate our desires and expectations, inform us when we find ourselves stuck in unpleasant and unfulfilling situations, and motivate us to furnish our lives with meaning, interest, and value. Boredom, frustration, and anticipation aren't obstacles to our goals--they are our guides, propelling us into lives that are truly our own. (shrink)

It is almost unanimously acknowledged that the formation of Hegel’s philosophy was largely determined by the appropriation and further development of some fundamental achievements of Kant’s transcendental idealism - first of all his polemic against the “old metaphysics” or, as Hegel also said, the “empty metaphysics of the understanding”. The most decisive assumption of this metaphysics consisted, indeed, in the belief that the totality of our universe could be exhaustively resolved into a plurality of isolated entities, devoid of any “internal,” (...) essential, mutual relations. Each entity was, as a consequence, considered to be only abstractly self-identical and so different from any other. In such a perspective, the absolute, the infinite, the divine, could not but be conceived as being substantially alien to the human mind’s innermost life and essence, as a merely motionless object, absolutely transcendent to the self-creative process in which our rational subjectivity essentially consists. Kant’s critique - especially by virtue of his conception of knowledge as an “a priori synthesis” of intuition and category, of experience and concept, which finds the ultimate condition of its possibility not in its conformity to a presupposed objectivity, but precisely in the original unity of self-consciousness, the “I-think-in general” - has certainly by now rendered unsustainable the strict dualism typical of such a metaphysics, and in particular its pretension of rationally “demonstrating” the existence and the most general properties of the alleged merely transcendent absolute. Whereas Kant’s idealism seems nevertheless to limit itself to the statement and foundation of this simply critical and negative outcome of the transcendental analysis of our knowledge, the ultimate aim of Hegel’s whole philosophy consists rather in the attempt explicitly and systematically to develop a conception of the universe, according to which the universe, far from dividing into a plurality of absolutely different and exclusive entities, instead constitutes itself as a unique, absolute, organic totality, in which any immediate difference and opposition tends to merge, to “reconcile” itself in a superior and deeper “dialectical” unity, which is both divine and human, infinite and finite, identical and different, ideal and real, eternal and in a process of becoming, transcendent and immanent. Every one of its determinate aspects and grades of development, every element into which it differentiates itself, thus turns out to be intimately immanent in, and connected with, every other, and finally in and with the absolute totality itself. Totum in toto et in qualibet parte. “Outside” of such unique, concrete totality, there appear to be but empty, irrational, unreal abstractions: first of all the A = A of formal logic and the absolutely transcendent God of the “old metaphysics.”. (shrink)

The philosophic, historical, and literary Italian culture of the first half of our century was largely dominated by a trend of thought that can be correctly called “Neo-idealist,” the most prominent exponents of which were Giovanni Gentile and Benedetto Croce. The latter’s very broad scientific activity moved, and attained its highest and most durable achievements, in the ambit of the theory and history of Italian and European literature, of civil historiography, and of social and political theory. We cannot here attempt (...) even a very sketchy explanation, interpretation, and evaluation of the undoubtedly remarkable contribution which Croce’s scientific work was able to offer to the development of our century’s European culture. Here we shall confine our critical interest only to the philosophical theories stricto sensu elaborated by Croce in the course of his wider historiographic activities. They stem indeed from a personal reading, interpretation, and criticism of Hegel’s speculative idealism; and he proposed them to contemporary scholars as the extreme and most mature stage of modern thought’s whole development. Thus, should they turn out to be generally tenable, any attempt today to vindicate Hegel’s thought as fully up-to-date and valid, at least with respect to its deepest logical-metaphysical and methodological-dialectical “substance,” could not but appear to be openly anachronistic. Whence, then, the inescapable need for a careful critical examination of their content, meaning, and real plausibility in the present historical-cultural situation. (shrink)

This article offers a general “immanent” critique of Derrida’s Deconstructionism, whose positive outcome is an argument for the continuing viability of a Hegel-oriented idealistic metaphysics. Derrida’s thought is construed as an unspokenly skeptical and nihilistic development of Heidegger’s existential ontology and of the sensu latiori “structuralist” trend of contemporary human sciences. The main difficulties pointed out hinge on (§ 1) the relationship deconstructionism establishes between thought and language, speech and writing, and phonetic and non-phonetic writing, (§ 2) its paradoxical concept (...) of “transcendental writing” as the “origin” of empirical writing and of the “trace” as more “original” than original reality; and, finally, (§ 3) its specification of the alleged “radical other” to metaphysical thought as writing, difference, and literature. (shrink)

The historical origin of the concept of ‘intentionality’, as is well-known, is very remote, dating back to the age of scholastic philosophy. In the epistemological theories worked out by medieval thinkers, from Thomas Aquinas up to the latest minor exponents of the nominalistic trend, the concept of ‘intentio’ is very often to be found, there playing a role of undoubtedly primary importance. Sometimes it means the universal ‘concept’ abstracted by the human understanding from sense datum; sometimes, instead, both the act (...) through which human intelligence directs itself towards the object of its cognition, the material ‘thing’, and the reflective act by virtue of which it refers to its subjective representation of the external ‘res’. In any case, it evidently turns out to be a fundamental function of any knowing whatsoever. (shrink)