ObjectiveTo identify the ethical challenges associated with the development and implementation of new tuberculosis drugs and diagnostics.MethodsTwenty-three semi-structured qualitative interviews conducted between December 2015 and September 2016 with programme administrators, healthcare workers, advocates, policymakers, and funders based in the Americas, Europe, and Africa. Interviews were analysed using thematic analysis.ResultsDivergent interests and responsibilities, coupled with power imbalances, are a primary source of ethical challenges; the uncertain risk profiles of new drugs present an additional one. Although this challenge can be partially mitigated (...) through stringent pharmacovigilance, respondents highlighted that high-burden countries tend to lack the resources to facilitate safe implementation. Increased advocacy and community engagement are considered an ethical imperative for future TB development and implementation.ConclusionsThis project helps identify some of the ethical challenges of new TB technologies. It demonstrates that investigating ethical challenges through qualitative research is one way to apprehend the difficulty of implementing new TB technologies. Addressing this difficulty will require that those in positions of power reconsider their interests in relation to disempowered communities.Policy implicationsEfforts to build consensus regarding what values should underpin the global governance of TB research, prevention, and care are essential to facilitate the ethical implementation of new TB technologies. (shrink)

This paper investigates how and when pairs of terms such as “local–global” and “im Kleinen–im Grossen” began to be used by mathematicians as explicit reflexive categories. A first phase of automatic search led to the delineation of the relevant corpus, and to the identification of the period from 1898 to 1918 as that of emergence. The emergence appears to have been, from the very start, both transdisciplinary (function theory, calculus of variations, differential geometry) and international, although the AMS-Göttingen connection played (...) a specific part. First used as an expository and didactic tool (e.g. by Osgood), it soon played a crucial part in the creation of new mathematical concepts (e.g. in Hahn’s work), in the shaping of research agendas (e.g. Blaschke’s global differential geometry), and in Weyl’s axiomatic foundation of the manifold concept. We finally turn to France, where in the 1910s, in the wake of Poincaré’s work, Hadamard began to promote a research agenda in terms of “passage du local au general.”. (shrink)

This paper delves into the work of Clive L. Spash, a British radical ecological economist well-known in his field who currently holds a professorship at the Vienna University of Economics and Business. We start with an examination of the principles of his “social ecological economics.” We then critically evaluate his attack on economic growth and his perspective on the standard economic models of climate change. Lastly, we explore his approach to science as a theoretical pursuit and his policy recommendations. The (...) first version of this paper was given as a keynote lecture at the 7th Austrian Economics Meeting Europe, May 12-13, 2023, Université Catholique de l’Ouest, Angers, France, and a second version at the Summer University in Political Economy, July 20-22, 2023, Aix-Marseille University, France. I wish to thank the organizers of these conferences, and also the anonymous referees whose remarks have been taken into account to improve the paper. (shrink)

This contribution presents the fundamentals of an amazement laboratory as a methodological means of transforming an object of disappointment into an object of desire for the researcher. First, the authors report on a Spinozist reading of their affects caused by their confrontation with a foreign material to the field of psychology, a docu-soap opera about school dropout entitled « Les persévérants » (Ferron & Baer, 2014). They consider astonishment as an affect to renew the interest of the researcher for his (...) research subject. Then they examine its conditions of emergence. Finally, the conditions for setting up an amazement laboratory are illustrated by examples drawn from the literature and the authors practices. (shrink)

Research on folk epistemology usually takes place within one of two different paradigms. The first is centered on epistemic theories or, in other words, the way people think about knowledge. The second is centered on epistemic intuitions, that is, the way people intuitively distinguish knowledge from belief. In this paper, we argue that insufficient attention has been paid to the connection between the two paradigms, as well as to the mechanisms that underlie the use of both epistemic intuitions and theories. (...) We contend that research on folk epistemology must examine the use of both intuitions and theories in the pragmatic context of the game of giving and asking for reasons and, more generally, understand how these practices take place within the broader context of normative social cognition. (shrink)

Peu à peu, tandis que Virgile achève la description ethnographique de la ruche, un glissement s’opère dans son propos : il célèbre d’abord la chasteté des abeilles, et le renouvellement de l’espèce par une miraculeuse génération spontanée ; il explique ensuite leur admirable organisation sociale par un lien privilégié avec la divinité, puisque les abeilles posséderaient une « parcelle d’intelligence divine » ; après ce bref aperçu d’une mystique panthéiste, i...

In this article, I seek to make sense of the oft-invoked idea of 'public emergency' and of some of its (supposedly) radical moral implications. I challenge controversial claims by Tom Sorell, Michael Walzer, and Giorgio Agamben, and argue for a more discriminating understanding of the category and its moral force.

_Desire and Distance_ constitutes an important new departure in contemporary phenomenological thought, a rethinking and critique of basic philosophical positions concerning the concept of perception presented by Husserl and Merleau-Ponty, though it departs in significant and original ways from their work. Barbaras's overall goal is to develop a philosophy of what "life" is—one that would do justice to the question of embodiment and its role in perception and the formation of the human subject. Barbaras posits that desire and distance inform (...) the concept of "life." Levinas identified a similar structure in Descartes's notion of the infinite. For Barbaras, desire and distance are anchored not in meaning, but in a rethinking of the philosophy of biology and, in consequence, cosmology. Barbaras elaborates and extends the formal structure of desire and distance by drawing on motifs as yet unexplored in the French phenomenological tradition, especially the notions of "life" and the "life-world," which are prominent in the later Husserl but also appear in non-phenomenological thinkers such as Bergson. Barbaras then filters these notions through Merleau-Ponty. (shrink)

The ultimatum game is a simple bargaining situation where the behavior of people frequently contradicts the optimal strategy according to classical game theory. Thus, according to many scholars, the commonly observed behavior should be considered irrational. We argue that this putative irrationality stems from a wrong conception of metanormativity (the study of norms about the establishment of norms). After discussing different metanormative conceptions, we defend a Quinean, naturalistic approach to the evaluation of norms. After reviewing empirical literature on the ultimatum (...) game, we argue that the common behavior in the ultimatum game is rational and justified. We therefore suggest that the norms of economic rationality should be amended. (shrink)

Média a priori étranger à l’univers d’un cours universitaire en gestion des ressources humaines, la bande dessinée peut pourtant constituer un outil précieux permettant une distanciation et un décalage des représentations habituelles des étudiants. L’objectif de cet article est de décrire l’utilisation de l’album Obélix et Compagnie comme métaphore de la place du travail dans la société, et d’en discuter les apports et les limites.Although comic strips are, on the face of it, alien to the world of university classes in (...) human resources management, they can become a valuable tool in helping students to achieve the necessary distance from their usual representations. This article describes the use of the album “Obélix et Compagnie” as a metaphor of the workplace in society, and to discuss its contributions and limitations. (shrink)

In this article, I seek to make sense of the oft-invoked idea of ‘public emergency’ and of some of its radical moral implications. I challenge controversial claims by Tom Sorell, Michael Walzer, and Giorgio Agamben, and argue for a more discriminating understanding of the category and its moral force.

La notion d'espace sonore est devenue de plus en plus prégnante dans le domaine musical, plus particulièrement dans la musique électroacoustique. Mais comment la définir? Cette simple interrogation, dont la réponse semble évidente soulève cependant, lorsqu'elle est approfondie, une multitude d'ambiguïtés, sources de nouvelles réflexions. Comment l'écoute appréhende-t-elle l'espace? Comment s'immerge-t- elle en lui? Qu'appréhende-t-on lorsqu'on écoute? Et finalement, qu'est-ce qu'un son? Quelles en sont les limites spatiales et temporelles? Lorsque l'écoute se confronte à l'espace sonore, où se situe la (...) frontière entre perception et imagination? Tout au long du présent ouvrage, l'auteur essaie de mettre en évidence l'empreinte effective de l'écoute dans la structuration de l'espace. Il tente de montrer, en s'appuyant sur les théories esthétiques, pourquoi l'espace n'est pas pris en compte par les pensées sur la musique avant le XXe siècle. A partir de cette observation et des dernières recherches phénoménologiques de Maurice Merleau-Ponty, il met en lumière le rôle essentiel du corps de l'auditeur dans notre perception de l'espace. Ensuite, il témoigne de la façon dont les compositeurs, à partir de la seconde moitié du XXe siècle et jusqu'à aujourd'hui, n'ont cessé de développer une implication active de l'écoute, ce qui a progressivement favorisé l'émergence d'un espace musical dynamique et mouvant. Puis, au terme de sa réflexion, à l'aide des travaux sur l'énaction du neurobiologiste Francisco J. Varela, Renaud Meric s'emploie à reconstruire le lien esthétique étroit entre l'espace, l'écoute et l'imagination, lien encore peu examiné, pourtant fondamental pour comprendre notre relation complexe à la musique. (shrink)

Historical work on the emergence of sheaf theory has mainly concentrated on the topological origins of sheaf cohomology in the period from 1945 to 1950 and on subsequent developments. However, a shift of emphasis both in time-scale and disciplinary context can help gain new insight into the emergence of the sheaf concept. This paper concentrates on Henri Cartan’s work in the theory of analytic functions of several complex variables and the strikingly different roles it played at two stages of the (...) emergence of sheaf theory: the definition of a new structure and formulation of a new research programme in 1940–1944; the unexpected integration into sheaf cohomology in 1951–1952. In order to bring this two-stage structural transition into perspective, we will concentrate more specifically on a family of problems, the so-called Cousin problems, from Poincaré (1883) to Cartan. This medium-term narrative provides insight into two more general issues in the history of contemporary mathematics. First, we will focus on the use of problems in theory-making. Second, the history of the design of structures in geometrically flavoured contexts—such as for the sheaf and fibre-bundle structures—which will help provide a more comprehensive view of the structuralist moment, a moment whose algebraic component has so far been the main focus for historical work. (shrink)

Depuis son retour, j’étais rongé. J’abrégeais les conversations, évitais son regard. Malgré tous mes efforts pour paraître naturel, pour faire comme si de rien n’était, je sentais bien, piètre comédien, que chaque phrase sonnait faux, que chaque geste suintait la culpabilité. Dans ses yeux, la perplexité initiale fit bien vite place au soupçon, et ma feinte bonne humeur fut démantelée sans coup férir par d’éloquents silences, froids appels à cesser toute mascarade. Enferré comme je l’étais, a..

La quatrième Géorgique n’est pas le simple entrelacs d’une didactique et d’une esthétique délicate et raffinée. Un troisième fil complique et parachève la tresse : la description ethnographique de la vie des abeilles. Il n’est plus question de conseiller l’apprenti apiculteur ; Virgile change de registre, et rend compte scrupuleusement de l’organisation sociale de la ruche. On a pu parler à ce propos de « communiste monarchique » : les abe...

Comment se représenter sa propre vie ? Comment se figurer le déroulé des ans, tracer la ligne qui passe par tous les points saillants de notre mémoire et englobe les plages d’oubli qui nous firent, elles aussi, ce que nous sommes ? Plusieurs formes, plusieurs « patrons » sont à notre disposition. En premier lieu, le biologique : le compte des années superpose les visions d’un corps en croissance, puis en déclin, les mutations successives qui l’affectent, les marques qui s’y (...) inscrivent. S’y aj.. (shrink)

La première partie du livre IV met apparemment en œuvre le programme didactique des Géorgiques, Virgile multipliant les conseils à l’apiculteur, quant au choix du lieu pour la ruche, à la sélection des espèces, aux aliments à mettre à disposition, à la récolte du miel, mais surtout aux précautions à prendre pour éloigner les abeilles des nombreux dangers potentiels qui les menacent, qu’il s’agisse du climat trop rigoureux ou de prédateu...

Insight problem solving was investigated with the matchstick algebra problems developed by Knoblich, Ohlsson, Haider, and Rhenius (1999). These problems are false equations expressed with Roman numerals that can be made true bymoving one matchstick. In a first group participants examined a static two-dimensional representation of the false algebraic expression and told the experimenter which matchstick should be moved. In a second group, participants interacted with a three-dimensional representation of the false equation. Success rates in the static group for different (...) problem types replicated the pattern of data reported in Knoblich et al. (1999). However, participants in the interactive group were significantly more likely to achieve insight. Problem-solving success in the static group was best predicted by performance on a test of numeracy, whereas in the interactive group it was best predicted by performance on a test of visuo-spatial reasoning. Implications for process models of problem solving are discussed. (shrink)

Can the state, as opposed to its individual human members in their personal capacity, intelligibly seek to avoid blame for unjustified wrongdoing by invoking excuses (as opposed to justifications)? Insofar as it can, should such claims ever be given moral and legal recognition? While a number of theorists have denied it in passing, the question remains radically underexplored. -/- In this article (in its penultimate draft version), I seek to identify the main metaphysical and moral objections to state excuses, and (...) begin to investigate their strength. I work from the ecumenical assumption that general understandings of modern states as group moral agents proper or as mere fictional points of imputation for individual behaviour are both plausible, and that the question of state excuses should be asked in terms of both paradigms. Issues addressed include: the lack of state consciousness/affect, the nature and relevance of developmental and executive defects in group agents, the value of state interests and how interests relate to plausible claims of excuses, the shortfall of responsibility argument for group responsibility and its interface with state excuses, the symbolic and consequential (dis)value that state excuses may have, as well as concerns that states are entities that should live up to outstandingly high virtuous standards of impartiality and equanimity. -/- I conclude that even if the range of excuses available to states does not overlap neatly with excuses available to ordinary individuals, some excuses may still be morally available to states. More generally, I emphasize the need for a systematic discussion of group excuses writ large, and of their relationship with the wider question of when group entities may legitimately be singled out to bear adverse normative consequences for wrongdoing. (shrink)

Developing Global Health Programming: A Guidebook for Medical and Professional Schools , edited by Jessica Evert, Paul Drain, and Thomas Hall, is reviewed. In spite of some editorial shortcomings, the book is a terrific aggregation of resources and reflections on the state of global health education that leaves readers with a multitude of useful and diverse tools, as well as directions about where to find additional ones.

La liberté a été assez largement réduite, dans la modernité occidentale, à une occurrence individualiste. C’est la liberté de l’individu « face au monde » et eu égard aux autres dont il s’agit surtout. Notre propos consistera en une critique de cette idée, au profit d’une compréhension relationnelle de la liberté. Il apparaîtra que nous avons besoin de soutien mutuel pour être et rester libre et que, à l’heure de l’Anthropocène, c’est la Terre qui nous soutient qui a elle aussi (...) besoin de toute notre attention, sans quoi les conditions de la liberté pourraient être très compromises. (shrink)

Is thinking necessarily linguistic? Do we _think with words_, to use Bermudez’s (2003) phrase? Or does thinking occur in some other, yet to be determined, representational format? Or again do we think in various formats, switching from one to the other as tasks demand? In virtue perhaps of the ambiguous nature of first-person introspective data on the matter, philosophers have traditionally disagreed on this question, some thinking that thought had to be pictorial, other insisting that it could not be but (...) linguistic. When any problem divides a community of otherwise intelligent rational thinkers, one suspects some deep conceptual confusion is at play. Indeed, we believe that the conceptual categories used to frame these and related questions are so hopelessly muddled that one could honestly answer “both simultaneously”, or “neither”, depending one what is meant by the alternatives. But let’s get our priorities straight. This paper first and foremost aims at defending what we believe to be a step in that direction of the proper view of thinking, a view we call the spatial-motor view. In order to do so, however, we have found it essential to start by address the conceptual confusion just alluded to. Accordingly, the paper proceeds in two steps. First a conceptual step, in which we reconsider some of the traditional categories brought into play when thinking about thinking. Then an empirical step, in which we offer empirical evidence for one of the views conceptually isolated during the first part of the work. Future version of this collaborative work will include a speculative step in which we spin out an evolutionary and developmental scenario whose function it is justify the spatial-motor view by showing how it fits into current evolutionary and developmental theories. (shrink)

One might think that if the majority of virtue signallers judge that a proposition is true, then there is significant evidence for the truth of that proposition. Given the Condorcet Jury Theorem, individual virtue signallers need not be very reliable for the majority judgment to be very likely to be correct. Thus, even people who are skeptical of the judgments of individual virtue signallers should think that if a majority of them judge that a proposition is true, then that provides (...) significant evidence that the proposition is true. We argue that this is mistaken. Various empirical studies converge on the following point: humans are very conformist in the contexts in which virtue signalling occurs. And stereotypical virtue signallers are even more conformist in such contexts. So we should be skeptical of the claim that virtue signallers are sufficiently independent for the Condorcet Jury Theorem to apply. We do not seek to decisively rule out the relevant application of the Condorcet Jury Theorem. But we do show that careful consideration of the available evidence should make us very skeptical of that application. Consequently, a defense of virtue signalling would need to engage with these findings and show that despite our strong tendencies for conformism, our judgements are sufficiently independent for the Condorcet Jury Theorem to apply. This suggests new directions for the debate about the epistemology of virtue signalling. (shrink)

This article introduces and discusses from a philosophical point of view the nascent field of neuroeconomics, which is the study of neural mechanisms involved in decision-making and their economic significance. Following a survey of the ways in which decision-making is usually construed in philosophy, economics and psychology, I review many important findings in neuroeconomics to show that they suggest a revised picture of decision-making and ourselves as choosing agents. Finally, I outline a neuroeconomic account of irrationality.

Is thinking necessarily linguistic? Do we think with words, to use Bermudez’s (2003) phrase? Or does thinking occur in some other, yet to be determined, representational format? Or again do we think in various formats, switching from one to the other as tasks demand? In virtue perhaps of the ambiguous na- ture of first-person introspective data on the matter, philosophers have tradition- ally disagreed on this question, some thinking that thought had to be pictorial, other insisting that it could not (...) be but linguistic. When any problem divides a community of otherwise intelligent rational thinkers, one suspects some deep conceptual confusion is at play. Indeed, we believe that the conceptual cate- gories used to frame these and related questions are so hopelessly muddled that one could honestly answer “both simultaneously”, or “neither”, depending one what is meant by the alternatives. But let’s get our priorities straight. This paper first and foremost aims at defending what we believe to be a step in that direc- tion of the proper view of thinking, a view we call the spatial-motor view. In order to do so, however, we have found it essential to start by addressing the conceptual confusion just alluded to. Accordingly, the paper proceeds in two steps. First a conceptual step, in which we reconsider some of the traditional categories brought into play when thinking about thinking. Then an empirical step, in which we offer empirical evidence for one of the views conceptually isolated during the first part of the work. Future version of this collaborative work will include a speculative step in which we spin out an evolutionary and developmental scenario whose function it is justify the spatial-motor view by showing how it fits into current evolutionary and developmental theories. (shrink)