This book examines the role of note-taking in ancient education as a pedagogical method, by taking readers on a stimulating analysis of lectures by ancient philosophers that were recorded by their students.

The essay analyses utopia as a key concept to investigate modern politics. It argues that looking at the works of Machiavelli and More in order to retrace the utopia-realism nexus permits to develop a valuable analytical tool to interpret the outset of political modernity.

ABSTRACTThe quality of medicines is generally adequately assured by manufacturers and regulatory authorities for well-resourced settings, while the implementation of existing quality standards is challenged in many low- and middle-income countries. This situation of multiple pharmaceutical standards raises the question whether it could ever be ethically justified to compromise on the quality assurance of medicines depending on what individuals, communities, or societies can afford. In this paper, we contend that ethically, any unjustified exceptions to medicines’ quality assurance represents a violation (...) of the principles of beneficence and non-maleficence. Exceptions are only acceptable in exceptional and temporary circumstances, if based on a meaningful quality risk assessment, guided by a rigorous ethical framework built on the principles of independence, technical competence, transparency, and accountability. We also discuss how such exceptional and temporary circumstances should be defined/justified.... (shrink)

Alison Simmons, in Simmons (1999), argues that Descartes in Meditation Six offered a teleological account of sensory representation. According to Simmons, Descartes’ view is that the biological function of sensations explains both why sensations represent what they do (i.e., their referential content) and why they represent their objects the way they do (i.e., their presentational content). Moreover, Simmons claims that her account has several advantages over other currently available interpretations of Cartesian sensations. In this paper, I argue that Simmons’ teleological (...) account cannot be sustained for both theoretical and textual reasons and that it does not have the advantages it is claimed to have. (shrink)

This article focuses on the assessment of mechanistic relations with specific attention to medicine, where mechanistic models are widely employed. I first survey recent contributions in the philosophical literature on mechanistic causation, and then take issue with Federica Russo and Jon Williamson’s thesis that two types of evidence, probabilistic and mechanistic, are at stake in the health sciences. I argue instead that a distinction should be drawn between previously acquired knowledge of mechanisms and yet-to-be-discovered knowledge of mechanisms and that both (...) probabilistic evidence and manipulation are essential with respect to newly discovered mechanisms. (shrink)

This contribution claims that the two fundamental notions of causation at work in the health sciences are manipulative and mechanistic, and investigates what kinds of evidence matter for the assessment of causal relations. This article is a development of our 2007 article, ‘Plurality of Causality’, where we argue for a pluralistic account of causation with an eye to econometrics and a single medical example. The present contribution has a wider focus, and considers the notion of evidence within a whole range (...) of disciplines belonging to the health sciences. Section 1 addresses the relations between kinds of evidence and causal accounts, and it is shown how different notions of causation can be employed in various medical cases. Section 2 calls attention to issues crucial for any adequate epistemological theory of causation, such as the distinctions between types and tokens, observational and experimental regimes, explanation and prediction. Lastly, the notion of context is articulated, highlighted in its role in the assessment of causal links. All these issues are tackled in the framework of what we label a ‘bottom–up’ epistemology. (shrink)

Research represents an essential component of the response to infectious disease outbreaks and to other public health emergencies, whether they are localised, of international concern, or global. Research conducted in such contexts also comes with particular ethics challenges, the awareness of which has significantly grown following the Ebola outbreak in West Africa, the Zika outbreak in Latin America and the COVID-19 pandemic. These challenges include the need for implementing meaningful community engagement with the researched communities, not just to build unidirectional (...) trust towards the research team, but to achieve a genuine and mutually respectful partnership before, during and after the research. Here, we describe the real-life experience of 10 well-established research clinics in Nairobi, where a successful experience of community engagement linking prevention and care to research was interrupted during the COVID19 pandemic. We contrast this experience with the concept and processes of community engagement as described in selected scientific manuscripts and guidelines, to formulate some conclusions and recommendations. We contend that more action is needed, from research ethics committees and other key-research stakeholders, to align policies and practices with ethics guidance and with evidence-based recommendations from the academic literature, to achieve meaningful community engagement during emergency research, irrespective of the scale and location of an outbreak or public health crisis. Failure to do so, will aggravate the (postcolonial) asymmetries of power in global health and local systems. (shrink)

In this paper I argue against the received view that the anti‐nativist arguments of Book I of Locke's Essay conclusively challenge nativism. I begin by reconstructing the chief argument of Book I and its corollary arguments. I call attention to their dependence on (what I label) “the Awareness Principle”, viz., the view that there are no ideas in the mind of which the mind either isn't currently aware or hasn't been aware in the past. I then argue that the arguments' (...) dependence on this principle is question begging on two counts. Unless this principle is defended, Locke's arguments beg the question against Descartes and Leibniz because their nativism implies the denial of the Awareness Principle. And even when Locke defended the principle, his arguments remain question begging because they presuppose the empiricism they aim to prove. The disclosure of the question‐begging status of these arguments debunks a seemingly powerful way of attacking nativism. (shrink)

A theater that heals is not a theater that offers answers and ?medicines? that guarantee to cure weaknesses and fragilities people meet but it is an open organization, which questions itself, which brings out ambivalence and ambiguity, diversity, weaknesses, and which leaves room for possible interpretations and narratives, the play of imagination, and the development of innovative and creative processes of people in society.

Current research on choice overload has been mainly conducted with choice options not associated with specific brands. This study investigates whether the presence of brand names in the choice set affects the occurrence of choice overload. Across four studies, we find that when choosing among an overabundance of alternatives, participants express more positive feelings (i.e., higher satisfaction/confidence, lower regret and difficulty) when all the options of the choice set are associated with familiar brands, rather than unfamiliar brands or no brand (...) at all. We also find that choice overload only appears in the absence of brand names, but disappears when all options contain brand names—either familiar or unfamiliar. Theoretical and practical implications are discussed. (shrink)

i. M is positive in M . ii. M is positive (negative) in P Q iff M is positive (negative) in P . iii. M is positive (negative) in P Q iff M is positive (negative) in Q, and P denotes..

1 Recognition Device . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2 Classical Categorial Grammar. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 3 Classical (...) Categorial Grammar. Examples . . . . . . . . . . . . . . . . . . . . . 5 4 Logic Grammar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 5 Lambek calculus. Examples . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 6 Lambek calculus. Semantics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 7 Lambek calculus. Advantages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 8 Derivations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 9 Residuated and Galois Connected Functions . . . . . . . . . . . . . . . . . . 14 10 Interpretation of the Constants. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 11 Nonveridical Functions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 12 Dutch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 13 Classification of NPIs in Dutch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 14 Antilicensing Relation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20.. (shrink)

Polarity Items are linguistic expressions known for being a ‘lexically controlled’ phenomenon. In this paper we show how their behavior can be implemented in a deductive system. Further- more, we point out some possible directions to recast the deductive solution into a Tree Ad- joining Grammar system. In particular, we suggest to compare the proof system developed for Multimodal Categorial Grammar (Moot & Puite, 1999) with the Partial Proof Trees proposed in (Joshi & Kulick, 1997).

In this paper we present a logical system able to compute the semantics of both declarative and interrogative sentences. Our proposed analysis takes place at both the sentential and at the discourse level. We use syntactic inference on the sentential level for declarative sentences, while the discourse level comes into play for our treatment of questions. Our formalization uses a type logic sensitive to both the syntactic and semantic properties of natural language. We will show how an account of the (...) linguistic data follows naturally from the logical relations inherent in the type logic. (shrink)

In this paper we draw some connection between the relation linking polarity items with their licensors, and the one holding between wh-phrases and weak-islands. Moreover, we briefly sketch how these relations can be modelled into Categorial Type Logic.

The article presents the first results we have obtained studying natural reasoning from a proof-theoretic perspective. In particular we focus our attention on monotonic reasoning. Our system consists of two parts: (i) A Formal Grammar – a multimodal version of classical Categorial Grammar – which while syntactically analysing linguistic expressions given as input, computes semantic information (In particular information about the monotonicity properties of the components of the input string are displayed.); (ii) A simple Natural Logic which derives (monotonicity) inferences (...) using as vehicle the parsed output. The monotonicity markers assigned in the lexicon are propagated through the proofs via a combination of the structural and the logical rules for the unary operators of Multimodal Categorial Grammar (MMCG) [Moo97]. We have chosen to work with an expressive ‘grammar logic’, in order to avoid the use of extra-logical marking devices and extra-logical structural reasoning. Having MMCG as parser, our system is able to make the derivations simply within the logic. This new approach makes the implementation of the theory an easier task. We have implemented the theoretical results, so far obtained, using Grail, a theorem prover for Categorial Grammar Logics [Moo98]. (shrink)

A partire dal corpus degli Scritti sulla donna, l'articolo intende mostrare come nel pensiero di Edith Stein vi sia il ricorrere di alcuni nuclei tematici soggetti a un sempre maggiore lavoro di scavo e di approfondimento, nella consapevolezza - maturata alla scuola di Husserl -della inesauribilitÀ della realtÀ. In particolare, dopo aver ricordato la funzione ontologica della filosofia nell'indagine sull'essere umano, che consente di parlare di specie e di individualitÀ, vengono qui toccate le questioni del rapporto fra specie e tipo, (...) della mutabilitÀ o meno della specie, della peculiaritÀ dell'anima femminile, e viene evidenziato come esse o siano il risultato di ricerche condotte in precedenza o contengano in nuce elementi di una riflessione portata avanti dalla filosofa tedesca in tempi e opere successivi. (shrink)

The notion of causal evidence in medicine has been the subject of wide philosophical debate in recent years. The notion of evidence has been discussed mostly in connection with Evidence Based Medicine and, more in general, with the assessment of causal nexus in medical, and especially research contexts. “Manipulative evidence” is one of the notions of causal evidence that has stimulated much debate. It has been defined in slightly different ways, attributed different relevance, and recently placed at the core of (...) Gillies’ “action-related theory of causality”, a view specifically meant to address causation in medicine. While in general sympathetic to Gillies’ account, and totally convinced of the relevance of manipulative evidence and different sorts of interventions in the biomedical sciences, we believe that some further qualifications are needed to allow the notion of manipulative evidence to better express features of medical practice. In particular, we provide some qualification of the role of “interventional evidence” proposed by Gillies, suggesting a distinction between “interventional evidence” and “evidence for interventions”. A case study from research on rare diseases is analyzed in depth and a multifaceted notion of manipulative evidence put forward that allows better understanding of what manipulations in medical contexts amount to and what their targets are. (shrink)

In medical research, the ethical principle of respect for persons is operationalized into the process of informed consent. The consent tools should be contextualized and adapted to the different socio-cultural environment, especially when research crosses the traditional boundaries and reaches poor communities. We look at the challenges experienced in the malaria Quinact trial, conducted in the Democratic Republic of Congo, and describe some lessons learned, related to the definition of acceptable representative, the role of independent witness and the impact of (...) socio-economic vulnerability. To ensure children's protection, consent is required by the parents or, in their absence, by a legally mandated representative. In our setting, children's responsibility is often entrusted permanently or temporarily to relatives or friends without a tribunal mandate. Hence, a notion of ‘culturally acceptable representative’ under supervision of the local Ethics Committee may be more suitable. To ensure protection of illiterate subjects, an independent witness is required to confirm that the consent was freely given. However, in low-literacy contexts, potential witnesses often don't have any previous relationship with patient and there may be power-unbalance in their relationship, rather than genuine dialogue. In poor communities, trial participation may be seen as an opportunity to secure access to healthcare. Poverty may also lead to ‘competition’ to access the research-related benefits, with a risk of disturbance at societal or household level. Adjusting consent procedures to sociocultural and socioeconomic realities is essential for fulfilling the underlying ethical principles. This requires a collaborative dialogue between researchers, regulators and ethics committees. (shrink)