Aging is characterized by the decline and deterioration of functional cells and results in a wide variety of molecular damages and reduced physical and mental capacity. The knowledge on aging process is important because life expectancy is expected to rise until 2050. Aging cannot be considered a homogeneous process and includes different trajectories characterized by states of fitness, frailty, and disability. Frailty is a dynamic condition put between a normal functional state and disability, with reduced capacity to cope with stressors. (...) This geriatric syndrome affects physical, neuropsychological, and social domains and is driven by emotional and spiritual components. Sarcopenia is considered one of the determinants and the biological substrates of physical frailty. Physical and cognitive frailty are separately approached during daily clinical practice. The concept of motoric cognitive syndrome has partially changed this scenario, opening interesting windows toward future approaches. Thus, the purpose of this manuscript is to provide an excursus on current clinical practice, enforced by aneddoctical cases. The analysis of the current state of the art seems to support the urgent need of comprehensive organizational model incorporating physical and cognitive spheres in the same umbrella. (shrink)

The well-replicated observation that many people maintain mental health despite exposure to severe psychological or physical adversity has ignited interest in the mechanisms that protect against stress-related mental illness. Focusing on resilience rather than pathophysiology in many ways represents a paradigm shift in clinical-psychological and psychiatric research that has great potential for the development of new prevention and treatment strategies. More recently, research into resilience also arrived in the neurobiological community, posing nontrivial questions about ecological validity and translatability. Drawing on (...) concepts and findings from transdiagnostic psychiatry, emotion research, and behavioral and cognitive neuroscience, we propose a unified theoretical framework for the neuroscientific study of general resilience mechanisms. The framework is applicable to both animal and human research and supports the design and interpretation of translational studies. The theory emphasizes the causal role of stimulus appraisal (evaluation) processes in the generation of emotional responses, including responses to potential stressors. On this basis, it posits that a positive (non-negative) appraisal style is the key mechanism that protects against the detrimental effects of stress and mediates the effects of other known resilience factors. Appraisal style is shaped by three classes of cognitive processes – positive situation classification, reappraisal, and interference inhibition – that can be investigated at the neural level. Prospects for the future development of resilience research are discussed. (shrink)

The aim of the paper is to give an account of Peter Winch's conception of persuasion. According to Winch, persuasive arguments are those carried out in order to let an interlocutor with a different world picture, and thus a different epistemology, see the point of our practices and beliefs. This involves convincing him of the fact that his way of thinking is neither unique nor better than other ones. Furthermore, given that there is no guarantee that one can arrive at (...) a complete understanding of alien practices, persuasion may, in some cases, aim at the impossible. (shrink)

Rationalitat hat religiose und andere metaphysisch anspruchsvolle Grossen in ihrer ehemals privilegierten Stellung als Begrundungsinstanzen in der Moralphilosophie abgelost. David Gauthier hat mit Morals by Agreement hier fur den moralischen Kontraktualismus die bisher am besten elaborierte Theorie vorgelegt, die auch die Methoden der modernen Entscheidungs- und Spieltheorie einbezieht. Die zentrale Herausforderung besteht in dem Erbringen des Nachweises, dass es in einer Gesellschaft mit ungleicher Machtverteilung fur alle Personen rational ist, einen Kooperationsvertrag einzugehen, der von Anfangsbedingungen der Gleichheit ausgeht. Iturrizaga stellt (...) in seiner tief greifenden kritischen Analyse diesen Nachweis in Frage und liefert dabei zugleich eine umfassende Darstellung der Theorie Gauthiers.". (shrink)

The global age is distinguished by disobedience, from the protests in Tiananmen Square to the fall of the Berlin Wall, to the anti-G8 and anti-WTO demonstrations. In this book, Raffaele Laudani offers a systematic review of how disobedience has been conceptualized, supported, and criticized throughout history. Laudani documents the appearance of "disobedience" in the political lexicon from ancient times to the present, and explains the word's manifestations, showing how its semantic wealth transcended its liberal interpretations in the 1960s and (...) 1970s. Disobedience, Laudani finds, is not merely an alternative to revolution and rebellion, but a different way of conceiving radical politics, one based on withdrawal of consent and defection in relation to the established order. (shrink)

Developments in fields as diverse as biotechnology, animal cognition, and computer science have cast serious doubt on the common belief that human beings are unique and that only they should have dignity and basic rights. A movement referred to as ‘new dignitarianism’ has recently reclaimed human dignity to fend off the threats to human uniqueness that it perceives to arise from these developments. This ‘new’ dignitarianism, however, is not new at all. Drawing on a debate between two Enlightenment philosophers, this (...) article shows that dignitarianism has already surfaced in the eighteenth century as the negative image of another movement: naturalism. Building on this historical account, I propose to understand dignitarianism and naturalism as opposing ideal-types on a normative spectrum. Doing so allows us to see a thus-far neglected problem, which I call the Zero-Sum Problem: any gains a concrete theory makes by approximating one ideal-type, it loses by moving away from the other. I end by showing how accepting this fact is a first step to more practically viable theories that attempt to find a middle ground between the two ideal-types. (shrink)

Developments in fields as diverse as biotechnology, animal cognition, and computer science have cast serious doubt on the common belief that human beings are unique and that only they should have dignity and basic rights. A movement referred to as ‘new dignitarianism’ has recently reclaimed human dignity to fend off the threats to human uniqueness that it perceives to arise from these developments. This ‘new’ dignitarianism, however, is not new at all. Drawing on a debate between two Enlightenment philosophers, this (...) article shows that dignitarianism has already surfaced in the eighteenth century as the negative image of another movement: naturalism. Building on this historical account, I propose to understand dignitarianism and naturalism as opposing ideal-types on a normative spectrum. Doing so allows us to see a thus-far neglected problem, which I call the Zero-Sum Problem: any gains a concrete theory makes by approximating one ideal-type, it loses by moving away from the other. I end by showing how accepting this fact is a first step to more practically viable theories that attempt to find a middle ground between the two ideal-types. (shrink)

This paper analyzes how national institutions impact corporate social responsibility practices for small- and medium-sized enterprises in the food-processing industries of France and Morocco. In this study, CSR practices are defined around two main dimensions: corporate performance and the CSR approach. Qualitative data were collected during semi-structured interviews with SME managers in charge of CSR issues. We then performed a content analysis. Our study shows that there is a distinct difference between the CSR practices adopted by SMEs in France and (...) Morocco. Indeed, the findings suggest that under the rule-based governance system of France, most SMEs view CSR as an economic tool and it is adopted as an opportunity-seeking perspective anchored in the search for global performance. The findings also show that under the relationship-based governance system of Morocco, SMEs mainly see CSR from a constraint-reducing perspective. However, some Moroccan SMEs have begun to see the economic opportunities of CSR, especially in accessing foreign markets. (shrink)

Name der Zeitschrift: Byzantinische Zeitschrift Jahrgang: 109 Heft: 1 Seiten: 223-282.

Nico De Federicis - Lezioni su Leibniz - Journal of the History of Philosophy 40:3 Journal of the History of Philosophy 40.3 401-402 Book Review Lezioni su Leibniz Luigi Scaravelli. Lezioni su Leibniz . Edited by Gianfranco Brazzini. Soveria Mannelli: Rubbettino, 2000. Pp. 260. 15.49. Lectures on Leibniz publishes a series of lectures, edited by Gianfranco Brazzini, that were held by Luigi Scaravelli at the University of Pisa in the Academic year 1953/54. Scaravelli was a major ill-starred Italian scholar. Although (...) probably the most significant philosopher in Italy after the death of Benedetto Croce, he nevertheless remained quite unknown. This collection of lectures offers an exceptional opportunity for insight into Scaravelli's philosophical approach. The.. (shrink)

The recent discovery of a fragmentary manuscript of Utpaladeva’s long commentary (Vivṛti or Ṭīkā) on his own Īśvarapratyabhijñā-kārikā (ĪPK) and Vṛtti enables us to assess the role of this work as the real centre of gravity of the Pratyabhijñā philosophy as a whole, though the later Śaiva tradition chose instead Abhinavagupta’s Vimarśinī as the standard text. This brilliant, and more compact and accessible, text was copied and copied again during the centuries and became popular in south India too, where a (...) number of manuscripts in the principal southern scripts are still available. The success of a particular commentary is very often the indirect cause of the decline of the others, which are less and less read and, consequently, copied, until their complete or almost complete loss. Of the lengthy and difficult Vivṛti by Utpaladeva—corresponding to the extent of 8,000 ślokas (hence the traditional denomination of Aṣṭasāhasrī)—the fragmentary śāradā manuscript that has come to light covers only the section ĪPK I.3.6 through I.5.3. Although the portion of the recovered text is comparatively short (33 folios), it proves to be particularly important in the economy of Pratyabhijñā philosophy due to the crucial points being dealt with there at great length, always in a hard-fought debate with the logical-epistemological school of Buddhism. (shrink)

This paper discusses Kant’s dealing with a fundamental of modern politics, that is, the concept of sovereignty, as well as its own capacity to reshape political order. Overcoming failures and fallacies that traditionally such a concept has maintained, Kant’s political philosophy focuses on the way to reach international peace institutionally. Starting from the discussion of contradiction in sovereignty, the paper briefly analyzes the analogy between individuals and states; finally, core elements of Kant’s cosmopolitan thought will be presented. Kant’s project basically (...) seeks to rewrite the early modern relation between politics and philosophy promoting republicanism, which is, mainly, a theory that shares state’s powers and defends representation. Extending such a political way from domestic to a world domain, Kant’s final solution for a World Republic implies a change of paradigm, by which modern sovereignty gets reassessed into a blended institutionalized coercion that emphasizes vertical power-sharing, so it realizes a cosmopolitan model of world order. (shrink)

Name der Zeitschrift: Nietzscheforschung Jahrgang: 21 Heft: 1 Seiten: 149-168.

A major characteristic of the aristocratic attitude—and I would not know how to better define the flavor that pervades the whole of Abhinavagupta’s work—is the downgrading of all painful effort, seen as a plebeian feature. The aristocrat intends to show that what inferior people can achieve only at the cost of long and painful exercises is accessible to him promptly and very easily. One of the recurring qualifications for Abhinavagupta’s attitude to the spiritual path is precisely absence of effort, absence (...) of exertion or fatigue, easiness. This can be clearly detected in Abhinavagupta’s attitude to yoga, or, to be more precise, to Pātañjala yoga. In the summary of the topics of the Tantrāloka, at the end of Āhnika I, he lists “uselessness of yogāṅgas.” When all yogāṅgas, abhyāsa, vairāgya, etc., are viewed from the peak of the highest aesthetically marked spiritual experiencer, they are condemned unreservedly. On the other hand, after delivering such a pitiless death sentence, Abhinavagupta seems to gracefully suspend it, and allow common people to follow pāśavayoga ‘yoga for limited souls’ in the context of the “minimal means” with the motivation that after all everything is made of everything, and, as the MVU teaches, “nothing is to be prescribed, nothing to be prohibited.”. (shrink)

A somewhat problematic book has recently been devoted to one of the most fascinating works of Kashmirian Śaiva Advaita: the Śivadṛṣṭi by Somānanda. This furnishes the occasion for broader reflection on the role of philology in dealing with the complex texts of the Pratyabhijñā tradition.

REM sleep behaviour disorder is a REM sleep-related parasomnia which may be considered a “dissociated state of wakefulness and sleep”, given that conflicting elements of REM sleep and of wakefulness coexist during the episodes, leading to motor and behavioural manifestations reminiscent of an enacted dream. RBD has been reported in association with α-synucleinopathies: around a third of patients with Parkinson’s disease have full-blown RBD.Recent data indicate that PD patients with RBD are more prone to hallucinations than PD patients without this (...) parasomnia. However it is still not clear why RBD in PD is associated with an increased prevalence of VHs.Data exist which suggest that visual hallucinations in PD may be the result of untimely intrusions of REM visual imagery into wakefulness. RBD, which is characterised by a REM sleep dissociation pattern, might be a condition that particularly favours such intrusions. However, other hypotheses may be advanced. In fact, deficits in attentional, executive, visuoperceptual and visuospatial abilities have been documented in RBD and found to occur far more frequently in PD with RBD than in PD without RBD. Neuropsychological deficits involving visual perception and attentional processes are thought to play an important role in the pathophysiology of VHs. On this basis, RBD in PD could be viewed as a contributory risk factor for VHs. (shrink)

This essay discusses the relevance of Herbert Marcuse’s One-Dimensional Man for contemporary radical politics. It approaches the topic from an unconventional perspective: the untimely nature of One-Dimensional Man, i.e., its being conceived in the 1940s as an answer to the crisis of Marxism after the defeat of European communist revolutions in the early twentieth century, and published in the 1960s in the very moment when the postwar stabilization was to collapse. From this perspective, its relevance for a political theory and (...) praxis of global radical movements is not to be found in its main concepts and categories, but on its shortcuts and limits, especially those related to political subjectivity. Shortcuts and limits which are, mutatis mutandis, still ours. (shrink)

ABSTRACTIt has become a commonplace that human beings possess human rights ‘simply in virtue of being human’. Exactly what this formula entails and whether it is cogent remains largely obscure, however. To remedy this situation, the article distinguishes between an interpretation of the formula according to which ‘being human’ is a practical condition for holding human rights and a reading which takes ‘being human’ to be a moral reason for holding human rights. It argues that only under the second reading (...) is there a limited sense in which it is correct that human beings possess human rights ‘simply in virtue of being human’. The article also considers if the concept of human dignity can provide a more convincing approach to the formula, and argues that it cannot. (shrink)