This paper is a discussion and a criticism of the account of the Philosophy of Resemblances which appears in the first chapter of Professor H. H. Price's Thinking and Experience.

BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

We present a one per cent measurement of the cosmic distance scale from the detections of the baryon acoustic oscillations in the clustering of galaxies from the Baryon Oscillation Spectroscopic Survey, which is part of the Sloan Digital Sky Survey III. Our results come from the Data Release 11 sample, containing nearly one million galaxies and covering approximately 8500 square degrees and the redshift range 0.2 < z < 0.7. We also compare these results with those from the publicly released (...) DR9 and DR10 samples. Assuming a concordance Λ cold dark matter cosmological model, the DR11 sample covers a volume of 13 Gpc3 and is the largest region of the Universe ever surveyed at this density. We measure the correlation function and power spectrum, including density-field reconstruction of the BAO feature. The acoustic features are detected at a significance of over 7σ in both the correlation function and power spectrum. Fitting for the position of the acoustic features measures the distance relative to the sound horizon at the drag epoch, rd, which has a value of rd,fid = 149.28 Mpc in our fiducial cosmology. We find DV = at z = 0.32 and DV = at z = 0.57. At 1.0 per cent, this latter measure is the most precise distance constraint ever obtained from a galaxy survey. Separating the clustering along and transverse to the line of sight yields measurements at z = 0.57 of DA = and H =. Our measurements of the distance scale are in good agreement with previous BAO measurements and with the predictions from cosmic microwave background data for a spatially flat CDM model with a cosmological constant. © 2014 The Author Published by Oxford University Press on behalf of the Royal Astronomical Society. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Hume Studies Volume XXI, Number 2, November 1995, pp. 315-332 Robertson, Hume, and the Balance of Power FREDERICK G. WHELAN William Robertson, like his Scottish Enlightenment colleague David Hume, practiced a kind of philosophic history which, although it appears to consist mainly of narratives of political and military events, is also designed to teach moral and political lessons of general significance and utility. The principal theme of Hume's (...) History of England, for example, is the growth of legal and constitutional government in connection with the emergence of modern society; Hume's narrative implicitly justifies both such a government and the moderate politics on which it depends. A theme of comparable importance in Robertson's History of Charles V (1769) is the emergence of a balance of power and thence a relatively stable international system among European states in the early sixteenth century, when the policy of balance first clearly appeared. As he declares in his Preface: The political principles and maxims then established still continue to operate. The ideas concerning the balance of power, then introduced or rendered general, still influence the councils of nations. (R 307)1 Robertson both describes the relevant policy decisions (especially the alliance between the traditional enemies, England and France, to counter the threat posed by Charles Vs unprecedentedly large empire) and justifies such policies as reasonable and beneficial.2 Frederick G. Whelan is at the Political Science Department, University of Pittsburgh, Pittsburgh PA 15260 USA. 316 Frederick G. Whelan In treating this theme, Robertson was taking up a topic that was of interest to Hume as well. Hume refers on a number of occasions to the sixteenth century balance of power in his History chapters on the reign of Henry VIII (1759),3 especially in the portion extending through the 1520s, and he treats the topic more systematically in his earlier essay "Of the Balance of Power" (1752).4 Hume like Robertson defends balance of power policies in general, and Hume certainly (Robertson probably) had a more particular reason for doing so: to justify contemporary British (Whig) foreign policy (and several wars), which since the reign of Louis XIV had aimed at maintaining a European counterbalance to France.5 Hume's and Robertson's favorable descriptions of the sixteenth century anti-Habsburg policy provide a useful background for defending the eighteenth century anti-Bourbon policy.6 Indeed, both Hume and Robertson probably exaggerated the prevalence of the balance of power, at least as a conscious policy, in the early sixteenth century; although they were no doubt correct in noting that something like the modern state system first began to take shape at that time, they seem to have projected the eighteenth century emphasis on balance backwards in time as a way of legitimizing it.7 Robertson sums up the fifty year period he covers by observing that the similar stage of development of the states of Europe at that time, together with the policy of balance, permitted the preservation of a fairly stable system of independent states that has lasted until the present: But the advantages possessed by one state were counterbalanced by circumstances favourable to others; and thus prevented any from attaining such superiority as might have been fatal to all. The nations of Europe in that age, as in the present, were like one great family.... There was not among them that wide diversity of character and of genius which, in almost every period of history, hath exalted the Europeans above the inhabitants of the other quarters of the globe, and seems to have destined the one to rule and the others to obey. (R 704) Hume's concern with contemporary policy, and with France, is more conspicuous: Europe has now, for above a century, remained on the defensive against the greatest force that ever, perhaps, was formed by the civil or political combination of mankind. And such is the influence of the maxim here treated of, that tho' that ambitious nation, in the five last general wars, have been victorious in four, and unsuccessful only in one, they have not much enlarged their dominions, nor acquired a total ascendant over EUROPE.... In the last three of these general Hume... (shrink)

Hanna Pitkin argues that Wittgenstein's later philosophy offers a revolutionary new conception of language, and hence a new and deeper understanding of ourselves and the world of human institutions and action.

The growing global prominence of Chinese state-owned enterprises brings new dimensions to our understanding of multi-national corporations and human rights issues. This article constructs a three-level framework that enables the mapping of transnational, national, and intra-organizational human rights pressures, and uses this framework to identify and analyze the human rights that Chinese SOEs report concern with. The analysis provided suggests that while China’s most global SOEs are subject to transnational pressures to respect all human rights, such pressures appear outweighed by (...) those encouraging them to concentrate on only some human rights within their national and intra-organizational environment. The article concludes by identifying a number of ways in which our conceptual framework and empirical findings can inform future research. (shrink)

Reason and Value collects 15 new papers by leading contemporary philosophers on themes from the work of Joseph Raz. Raz has made major contributions in a wide range of areas, including jurisprudence, political philosophy, and the theory of practical reason; but all of his work displays a deep engagement with central themes in moral philosophy. The subtlety and power of Raz's reflections on ethical topics make his writings a fertile source for anyone working in this area. Especially significant are his (...) explorations of the connections between practical reason and the theory of value, which constitute a sustained and penetrating treatment of a set of issues at the very center of moral philosophy as it is practiced today. The contributors to the volume acknowledge the importance of Raz's contributions by engaging critically with his positions and offering independent perspectives on the topics that he has addressed. The volume aims both to honour Raz's accomplishments in the area of ethical theorizing, and to contribute to an enhanced appreciation of the significance of his work for the subject. (shrink)