The paper is devoted to a conceptual model of cell patterning, based on a generalized notion of the epigenetic code of a cell determining its state. We introduce the concept of signaling depending both upon the spatial distance between cells and the distance between their cell states (s-distance); signaling can repel cells in the space of cell states (s-space) or attract them. The influence of different types of repelling signaling on the evolution of cells is considered. Stabilizing signaling, namely a (...) signaling monotonically decreasing with s-distance, causes the restoring of cell states after perturbations; destabilizing signaling, i.e., the one in which the signaling monotonically increases with s-distance, causes the appearance of pairs of cells with alternating cell states (one close to the state conventionally called “head”, and another close to the “tail” state). Non-monotonic (in s-space) signaling splits the cells into groups. The model shows that different types of signaling may provide different types of cellular patterns. General principles for applying this model to complex cellular structures are discussed. (shrink)

This paper is devoted to computer modelling of the development and regeneration of multicellular biological structures. Some species are able to regenerate parts of their body after amputation damage, but the global rules governing cooperative cell behaviour during morphogenesis are not known. Here, we consider a simplified model organism, which consists of tissues formed around special cells that can be interpreted as stem cells. We assume that stem cells communicate with each other by a set of signals, and that the (...) values of these signals depend on the distance between cells. Thus the signal distribution characterizes location of stem cells. If the signal distribution is changed, then the difference between the initial and the current signal distribution affects the behaviour of stem cells—e.g. as a result of an amputation of a part of tissue the signal distribution changes which stimulates stem cells to migrate to new locations, appropriate for regeneration of the proper pattern. Moreover, as stem cells divide and form tissues around them, they control the form and the size of regenerating tissues. This two-level organization of the model organism, with global regulation of stem cells and local regulation of tissues, allows its reproducible development and regeneration. (shrink)

The present study aims to elucidate whether insight problem solving could be facilitated by the cognitive component of humour. The authors take interest in whether the logical mechanisms of humour can affect how fast insight problems are solved. To that end, the authors conducted two experiments where participants solved insight problems after watching visual humorous stimuli such as videos and slideshows. The first experiment demonstrated the overall impact of facilitation by humour on insight problem solving; however, it did not show (...) any difference in how particular logical mechanisms of humour affect the solution time of insight problems. The second experiment showed that the cognitive component of humour could selectively affect insight problems whose difficulty stems from different sources. These results suggest that the cognitive component of humour, when operationalised as logical mechanisms and schema switching, contributes to solving insight problems. (shrink)

The purpose of the study is to study the main criteria that ensure the development of the regional agricultural industry. Since the development of the subjects of Russia is based on the need to search for new management tools that ensure the long-term development of all sectors of the national economy, state support and state regulation play a special role in the management of the industry. The research focuses on two groups of industry development. The first group includes labor, natural, (...) material, technical and financial resources. The second group includes investment, information, innovation, research and production, and socio-infrastructural resources. However, the second group of resource base factors has a direct impact on the final position of the agricultural sector. As a result, a mechanism for managing the resources of the agricultural sector of the region, based on the growth factors of the agricultural sector, has been identified. (shrink)

У статті розглянуто вплив візантійської антропології на думку Григорія Сковороди і преп. Паїсія Величковського. За допомогою порівняльно-історичного методу та методу історії традиції (tradition history) простежено застосування українськими богословами XVIIІ ст. візантійської патристичної спадщини. Доповнюючи нещодавнє дослідження М.Ґ.Бартоліні, присвячене розробці Сковородою ідей Александрійської школи патристики, стаття аналізує мотиви, позичені ним у Антіохійської школи. Це, зокрема, своєрідна філософія дозвілля та християнський епікуреїзм, що відлунює вчення Йоана Золотоуста про легкість і природність християнського способу життя. Порівняння містичної антропології двох богословів показало відмінність шляхів їхньої (...) інтроспекції, яка у Сковороди присвячена, передусім, самопізнанню, а в Паїсія – автентичному пошуку Іншого: Бога, наставника, подвижницької громади. (shrink)

У статті розглянуто основні педагогічні метафори, які побутували в Антіохійській школі патристики. Дослідження засноване, насамперед, на матеріалі гомілій свт. Іона Золотоуста De inani gloria, Adversus oppugnatores vitae monasticae, In Matthaeum, Ad populum Antiochenum, а також на окремих творах Феодорита Кирського і Северіана Габальського. Ці твори проаналізовано крізь призму теорії метафори П. Рікера, докладені Н. Райтом та Р. Хейзом до вивчення життєсвіту релігійних громад. Такий аналіз допоміг виявити у творах Золотоуста та інших антіохійців співіснування двох основних педагогічних метафор різного походження. Метафора (...) чистого аркушу, що походить з трактату Аристотеля De anima, розглядає процес освіти в категоріях активного формування педагогом ментальності вихованця. У Золотоуста ця метафора набуває вигляду складного палімпсесту, де первинний текст постійно записується новими шарами, редагується і відновлюється знову. До цього процесу взаємного навчання і редагування свт. Іоан закликає усіх своїх слухачів. Натомість метафора фортеці, укорінена в Павловій антропології і в Платоновій теорії анамнезису, імплікуючи значно більшу самодостатність особистості, застерігає від надмірного педагогічного конструктивізму. Ця парадигма представляє людський ум (νους) як храм або місто, збудоване за Божим задумом, що розвивається за законами, закладеними Творцем. Завдання педагога в такому сценарії – радше оберігати тонкий і складний внутрішній світ дитини від примітивної логіки оточення, щоб не перешкоджати її природному розвитку за Божим задумом. У Золотоуста, Феодорита та інших антіохійців співіснують обидві метафори, але метафора чистого аркушу – переосмисленого як палімпсест – докладається радше до просвіти дорослих християн, тоді як метафора фортеці застосовується стосовно виховання дітей. (shrink)

A nation cannot exist without national culture and national self-consciousness. These concepts are decisive in the development of the nation. Values are the priorities of any nation, determined by its culture and self-awareness. The national cool is the basis for the formation and development of national self-consciousness. The aim is to analyze the influence of national culture on the formation of national consciousness. Justify their objective and subjective factors of formation, which are based on the motivational core of personality behavior. (...) National culture and national self-consciousness are the main features of a nation, without which it cannot exist and develop as a whole. National culture and national self-consciousness are one whole of the spiritual world of nations and nationalities. The development of national culture and national self-consciousness is an objective regularity. Naturally, contradictions in this process will exist and demand their resolution or escalate into conflicts. With a timely solution, they will play the role of an indicator of national development. (shrink)

The article discusses teaching the analysis of documentary films from the standpoint of a discursive approach. The importance of teaching the analysis of documentary films is due to the specifics of audiovisual production. A documentary film is a polyosemiotic construct combined with verbal, pictorial and sound signs, which are important for the translator to take into account in the translation process. The discursive approach allows to teach future translators to analyze not only the work as a whole, but also to (...) analyze the historical and socio-cultural context in which it was created. (shrink)

The article analyzes the ethical and theological content of the apocryphal Syrian "autobiography" of St. Clement of Rome, as well as its early Slavic translation. The study uses historical-philosophical, patristic and philological methodology to outline the specific teachings, attributed to St. Clement by this Greek-speaking Syrian text from the pseudo-Clementine cycle. The methods of comparative textology and translation studies are used to analyze the features of the Slavic version of the work. The study revealed that, contrary to the ideas of (...) the publisher of the Slavic version, P. Lavrov, the translation was undoubtedly made according to the archaic, pre-metaphrasic version of the work. Therefore, it can be dated to the ninth century and come from the school of Cyril and Methodius. The popularity of the monument among Slavic readers is partly explained by the archaic features of the original version of the work preserved in the translation, such as graphic imagery, expressive presentation, and numerous dialogues. Such a lively account facilitated the perception of the conceptually rich ethical content of the work. At the heart of both Greek and Slavic versions is the ethical category of philanthropy, which figures as a central Christian virtue. Much of the Epitome is devoted to a detailed explanation of this category and its distinction from other virtues. In the original, the ethics of philanthropy is opposed to the astrological ideology represented by Clement’s father Faust. Faust's views are based on the natural philosophical ideas of the early Greek Stoics. Apostle Peter, Clement's teacher, responds to his arguments from the standpoint of Judeo-Christian monotheism, referring to the biblical history of his people. Thus, Hellenism is confronted with biblical monotheism. So, Epitome appears a kind of argument in the controversy between Gentile Christians and Judeo-Christians, which has troubled the Syrian Church for centuries. However, in translation, this clash of worldviews remains obscured, as the translator does not seem to recognize either the terminology of Stoic natural philosophy, or astrological issues, or the debate between the traditions of Peter and Paul in Syria. Thus, all the Stoic terminology of Faust is reduced to a single concept of "being". Therefore, in the translated version, the controversy is not so much between Christianity and astrology, as between ethics and "ontology". Instead, the translator enriches the philosophical outline of the work with polysemic Slavic vocabulary, which sheds new light on the role of the bishop in Peter’s instructions to Clement. Comparison of the Greek and Slavic versions of the Epitome – an autobiography attributed to St. Clement – with his only authentic work, 1Corinthians, allowed to draw another unexpected conclusion. All these works are not only devoted to one main problem - the restoration of peace in the controversial Christian community, but also offer similar ways out of the crisis through brotherly love, solidarity and respect for the otherness of the fellow Christians. This may indicate either that the author of the Syrian apocrypha was inspired by the true Epistle of Clement to the Corinthians, or that the image of St. Clement, that developed in the early tradition, dictated the message of the pseudo-epigraph quite powerfully. Due to this consonance, the apocryphal work of the Syrian Ebionites did to some extent acquaint Slavic readers with the ideas of Clement of Rome, whose only authentic work was almost unknown in the Middle Ages. (shrink)

The article reviews the assessment of the School of Antioch by the first Ukrainian hagiographer, St. Dymytriy Tuptalo. Methods: The comparative-historical methodology and, above all, the Tradition history method reveal not only explicit but also implicit links between Kyivan and Antiochian theology. Conclusions: Interpreting the 4th -5th-centuries theological collisions, Tuptalo consistently clung to the viewpoint of the School of Antioch, rejecting the accusals from the side of Alexandrian tradition. St. Dymytriy systematically reproduces in his Synaxarion the historical narratives of the (...) Antiochians. An unequivocal indicator of Dymytriy’s position is his attitude to Antioch's most controversial figures: in particular, he enlists Theodoret of Cyrrhus among the "holy fathers" and mentions Diodorus of Tarsus among the "Church luminaries", along with other figures of the Meletian party. Such an independent evaluation of the Antiochian heritage is undoubtedly due to the concordance of the theological thinking of Dymytriy with the worldview of the Antiochians. (shrink)

Исследование посвящено философскому осознанию природы духовности человека. Автор рассматривает духовность внутреннего мира человека как единство высших чувств души и нравственного сознания. Для специалистов в области философии, методологии науки.

The authors prove and describe the action of new networking mechanisms of formation of identities which arise in the context of societal transformations of the modern society. The networking mechanisms of identity formation represent a complex of interrelated and interdependent practices in global information and communication space, promoting individual and collective identification, interiorization and reflection. The complex includes the mechanism of network communication, mechanism of reflexive involvement of a person into the public space, mechanism of network topos-structuring and mechanism of (...) public crowdsourcing. The results of the empirical research show that the functionality of the mechanism of network communication for reproducing/positioning traditional identities and projecting new identities resides in its digital nature and a network ethos. The mechanism of reflexive involvement of individuals into the public space enables individual and collective actors to project the independent social worlds requiring the creation of their own virtualized public spaces that are closely linked with the common social space. The mechanism of network toposstructuring and mechanism of public crowdsourcing, forming situation and problem identities, have the high mobilization potential to update the activity of network communities in the form of individuals’ initiatives and large-scale civil movements where new sustained identities form which can also gain the protest nature. The authors come to conclusion that the complex of network mechanisms produces the dynamic matrix of the identity of a modern person allowing to take the opportunities for its development in the contemporary conditions of new social reality formation. At the same time, the complex of networking mechanisms is not stable; its content depends on those institutional practices which determine further conditions, processes and results of formation of identities, requiring their conceptual understanding and empirical research in social sciences. (shrink)

The authors prove and describe the action of new networking mechanisms of formation of identities which arise in the context of societal transformations of the modern society. The networking mechanisms of identity formation represent a complex of interrelated and interdependent practices in global information and communication space, promoting individual and collective identification, interiorization and reflection. The complex includes the mechanism of network communication, mechanism of reflexive involvement of a person into the public space, mechanism of network topos-structuring and mechanism of (...) public crowdsourcing. The results of the empirical research show that the functionality of the mechanism of network communication for reproducing/positioning traditional identities and projecting new identities resides in its digital nature and a network ethos. The mechanism of reflexive involvement of individuals into the public space enables individual and collective actors to project the independent social worlds requiring the creation of their own virtualized public spaces that are closely linked with the common social space. The mechanism of network toposstructuring and mechanism of public crowdsourcing, forming situation and problem identities, have the high mobilization potential to update the activity of network communities in the form of individuals’ initiatives and large-scale civil movements where new sustained identities form which can also gain the protest nature. The authors come to conclusion that the complex of network mechanisms produces the dynamic matrix of the identity of a modern person allowing to take the opportunities for its development in the contemporary conditions of new social reality formation. At the same time, the complex of networking mechanisms is not stable; its content depends on those institutional practices which determine further conditions, processes and results of formation of identities, requiring their conceptual understanding and empirical research in social sciences. (shrink)

We argue that the appraisal of models in social epistemology requires conceiving of them as argumentative devices, taking into account the argumentative context and adopting a family-of-models perspective. We draw up such an account and show how it makes it easier to see the value and limits of the use of models in social epistemology. To illustrate our points, we document and explicate the argumentative role of epistemic landscape models in social epistemology and highlight their limitations. We also claim that (...) our account could be fruitfully used in appraising other models in philosophy and science. (shrink)

While humans are the best of creations and God’s caliphs on Earth, such a status is always hard to achieve and necessitates many efforts and too much practice. This world also has a two-way path, one terminating in the lowest of the low and the other culminating in the highest of the high. It means that one way leads to misfortune and misery and the other to happiness and perfection. To attain happiness, accountability can be of utmost importance. Besides, the (...) purpose of human creation is closeness to God by preferring the right path, which is not often possible unless they speak the truth and make the best use of the enlightening teachings of the revelation to spot the bad and good, becoming aware of their own duties and responsibilities and ultimately putting them into effect. This research aimed to investigate the mediating role of values in the relationship between accountability and trust among Muslim managers and employees in Islamic organisations, using a descriptive method through a field study. The statistical population included 2500 senior Muslim managers and employees of Iraqi government organisations, selected via simple random sampling. In this research, structural equation modelling (SEM) analysis was recruited for data analysis in the Statistical Package for the Social Sciences (SPSS) and Analysis of a Moment Structures (AMOS). The study results demonstrated that accountability in Muslim managers and employees has a significant positive effect on trust (p = 0.45) and values (p = 0.81). Moreover, the findings revealed that values have a positive effect on reinforcing trust in Islamic organisations (p = 0.54), and above all bolster the relationship between accountability in managers and employees and organisational trust (p = 0.43).Contribution: The accountability of managers and employees can have a positive effect on individuals’ performance in organisations. In general, psychological pressures in organisations result in organisational transformation and then maintain values through trust-building. Such changes can be subsequently operationalized and have a profound impact on people’s behaviour by affecting work order and keeping them always growing, agile and diligent, in order to reach a new level of performance. (shrink)

Exclusionary defeat is Joseph Raz’s proposal for understanding the more complex, layered structure of practical reasoning. Exclusionary reasons are widely appealed to in legal theory and consistently arise in many other areas of philosophy. They have also been subject to a variety of challenges. I propose a new account of exclusionary reasons based on their justificatory role, rejecting Raz’s motivational account and especially contrasting exclusion with undercutting defeat. I explain the appeal and coherence of exclusionary reasons by appeal to commonsense (...) value pluralism and the intermediate space of public policies, social roles, and organizations. We often want our choices to have a certain character or instantiate a certain value and in order to do so, that choice can only be based on a restricted set of reasons. Exclusion explains how pro tanto practical reasons can be disqualified from counting towards a choice of a particular kind without being outweighed or undercut. (shrink)

Standard accounts of civil disobedience include nonviolence as a necessary condition. Here I argue that such accounts are mistaken and that civil disobedience can include violence in many aspects, primarily excepting violence directed at other persons. I base this argument on a novel understanding of civil disobedience: the special character of the practice comes from its combination of condemnation of a political practice with an expressed commitment to the political. The commitment to the political is a commitment to engaging with (...) others as co-members in the on-going political project of living together. I show how such an understanding of civil disobedience is superior to the Rawlsian strain of thought, which focuses on fidelity to law. Rawls was concerned with civil disobedience solely in the context of overriding political obligation. The project of characterizing a contestatory political practice that can be distinguished and used in a wider variety of contexts than Rawls is concerned with, including under illegitimate regimes, beyond the nation-state, or on behalf of anarchism, requires a different understanding of civil disobedience. (shrink)

Political legitimacy is best understood as one type of a broader notion, which I call institutional legitimacy. An institution is legitimate in my sense when it has the right to function. The right to function correlates to a duty of non-interference. Understanding legitimacy in this way favorably contrasts with legitimacy understood in the traditional way, as the right to rule correlating to a duty of obedience. It helps unify our discourses of legitimacy across a wider range of practices, especially including (...) the many evaluations we increasingly make of international institutions of various sorts, but also including domestic institutions. (shrink)

According to familiar accounts, Rousseau held that humans are actuated by two distinct kinds of self love: amour de soi, a benign concern for one's self-preservation and well-being; and amour-propre, a malign concern to stand above other people, delighting in their despite. I argue that although amour-propre can (and often does) assume this malign form, this is not intrinsic to its character. The first and best rank among men that amour-propre directs us to claim for ourselves is that of occupying (...) 'man's estate'. This does not require, indeed it precludes, subjection of others. Amour-propre does not need suppression or circumscription if we are to live good lives; it rather requires direction to its proper end, not a delusive one. (shrink)

CONTENIDO: Kant y la pedagogía - De la objetividad a la objetivación - De la tensión entre el investigador y el método - Interdisciplinariedad e investigación cualitativa en educación - Formación y subjetividad: epistemología, lenguaje y pedagogía - La pedagogía ante la tecnología como estructura del mundo de la vida - Alcances y limitaciones de la inteligencia artificial en pedagogía - A propósito de la informática en el mundo de la pedagogía y de la educación - La representación del conocimiento (...) y la inteligencia artificial - La lógica de las ciencias como didáctica: ¿un bastión de modernidad? - La educación del futuro como futuro de la educación - De la epistemología de la pedagogía a la filosofía de la educación. (shrink)

Dehaene and Naccache, Dennett and Jack and Shallice “see convergence coming from many different quarters on a version of the neuronal global workspace model†(Dennett, p. 1). (Boldface references are to papers in this volume.) On the contrary, even within this volume, there are commitments to very different perspectives on consciousness. And these differing perspectives are based on tacit differences in philosophical starting places that should be made explicit.  Indeed, it is not clear that different uses of “consciousness†and (...) “awareness†in this volume can be taken to refer to the same phenomenon. More specifically, I think there are three different concepts of consciousness in play in this issue. The global workspace model makes much more sense on one of these than on the others. (shrink)

The first thorough study in English of the multi-faceted system of Mou Zongsan, this book examines key influences on the New Confucian thinker and introduces his Kantian- and Mahāyāna Fo-inflected moral metaphysical reading of the Lu-Wang Learning of the Mind.