We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

This chapter explores a case study in contemporary fanaticism. We adopt Katsafanas’s conceptualization of fanaticism to make possible an in-depth discussion of and evaluation of a diffuse but important social movement — the anglophone manosphere. According to Katsafanas, fanatics are fruitfully understood as members of a group that adopts sacred values which they hold unconditionally to preserve their own psychic unity, and who feel that those values are threatened by those who do not accept them. The manosphere includes several social (...) movements, including incels, men’s rights activists, and men-going-their-own-way. We show that many members of these groups are well-characterized by Katsafanas’s theory of fanaticism, and that they have forged their fanatical group identity using tools that philosophers have tended to associate with more benign social movements and the task of “conceptual engineering.” Indeed, we think that manosphere groups have in many cases been more successful than more palatable liberationist movements, and that this case study in the dark side of conceptual engineering may be both sobering and informative. (shrink)

This paper presents five studies on the development and validation of a scale of intellectual humility. This scale captures cognitive, affective, behavioral, and motivational components of the construct that have been identified by various philosophers in their conceptual analyses of intellectual humility. We find that intellectual humility has four core dimensions: Open-mindedness (versus Arrogance), Intellectual Modesty (versus Vanity), Corrigibility (versus Fragility), and Engagement (versus Boredom). These dimensions display adequate self-informant agreement, and adequate convergent, divergent, and discriminant validity. In particular, Open-mindedness (...) adds predictive power beyond the Big Six for an objective behavioral measure of intellectual humility, and Intellectual Modesty is uniquely related to Narcissism. We find that a similar factor structure emerges in Germanophone participants, giving initial evidence for the model’s cross-cultural generalizability. (shrink)

Philosophy of ecology has been slow to become established as an area of philosophical interest, but it is now receiving considerable attention. This area holds great promise for the advancement of both ecology and the philosophy of science. Insights from the philosophy of science can advance ecology in a number of ways. For example, philosophy can assist with the development of improved models of ecological hypothesis testing and theory choice. Philosophy can also help ecologists understand the role and limitations of (...) mathematical models in ecology. On the other side, philosophy of science will be advanced by having ecological case studies as part of the stock of examples. Ecological case studies can shed light on old philosophical topics as well as raise novel issues for the philosophy of science. For example, understanding theoretical terms such as “biodiversity” is important for scientific reasons, but such terms also carry political importance. Formulating appropriate definitions for such terms is thus not a purely scientific matter, and this may prompt a reevaluation of philosophical accounts of defining theoretical terms. We consider some of the topics currently receiving attention in the philosophy of ecology and other topics in need of attention. Our aim is to prompt further exchange between ecology and philosophy of science and to help set the agenda for future work in the philosophy of ecology. The topics covered include: the role of mathematical models, environmental problem formulation, biodiversity, and environmental ethics. (shrink)

Holmes Rolston has defended certain forms of hunting and meat eating when these activities are seen as natural participation in the food chains in which we evolved. Ned Hettinger has suggested that some of Rolston’s principles that govern our interactions with plants and animals might appear to be inconsistent with Rolston’s defense of these activities. Hettinger attempts to show that they are not. We argue that Rolston’s principles are not consistent with hunting, given Hettinger’s modifications. In his defense of Rolston, (...) Hettinger has challenged animal welfare ethicists to show that they can value animal predation while consistently condemning human hunting. We answer that hunting and meat eating by humans are “cultural” rather than “natural” activities. (shrink)

Philosophers have often misunderstood Kierkegaard's views on the nature and purposes of God due to a fascination with his earlier, pseudonymous works. We examine many of Kierkegaard's later works with the aim of setting forth an accurate view on this matter. The portrait of God that emerges is a personal and fiercely loving God with whom humans can and should enter into relationship. Far from advocating a fideistic faith or a cognitively unrestrained leap in the dark, we argue that Kierkegaard (...) connects this God-relationship to (a particular kind of) evidence and even knowledge. However, such evidence and knowledge – and hence God himself – may remain hidden from many individuals due to misconceptions of God and misuses of the human will. (shrink)

We present two studies investigating the impact of causal perceptions and the moral emotions of anger, shame, and guilt on the justification of deviant workplace behavior. Study 1 tests our conceptual framework using a sample of undergraduate business students; Study 2 examines a population of practicing physicians. Results varied significantly between the two samples, suggesting that individual and contextual factors play an important role in shaping the perceptual and emotional processes by which individuals form reactions to undesirable affective workplace events. (...) Implications of these findings for the study of ethics, emotions, and attributions, as well as for promoting ethical behavior, are discussed. (shrink)

Recent work by Kahan et al. (2017) on the psychology of motivated numeracy in the context of intracultural disagreement suggests that people are less likely to employ their capabilities when the evidence runs contrary to their political ideology. This research has so far been carried out primarily in the USA regarding the liberal–conservative divide over gun control regulation. In this paper, we present the results of a modified replication that included an active reasoning intervention with Western European participants regarding both (...) the hierarchy–egalitarianism and individualism–collectivism divides over immigration policy (n = 746; considerably less than the preregistration sample size). We reproduce the motivated numeracy effect, though we do not find evidence of increased polarization of high-numeracy participants. (shrink)

Paul Lewis and Walter Gulick summarize and evaluate Mark Micthell’s new book, Michael Polanyi: The Art of Knowing, and Mitchell responds to their comments in this symposium article.

Environmentalists consider invasions by exotic species of plants and animals to be one of the most serious environmental problems we face today, as well as one of the leading causes of biodiversity loss. We argue that in order to develop and enact sensible policies, it is crucial to consider two philosophical questions: What exactly makes a species native or exotic, and What values are at stake? We focus on the first of these two questions, and offer some preliminary suggestions with (...) regard to the second. Through a series of case studies, we show that it is not always clear whether a species is native or exotic. We identify five possible criteria that could be used for distinguishing natives from exotics. Rather than identifying one of these criteria as the 'correct' one, we suggest that the concepts of 'native' and ' exotic ' function more like what some philosophers have called cluster concepts. That is, there are several characteristics that are typical of native species, and a corresponding set of characteristics that are typical of exotic species. None of these characteristics is either necessary or sufficient for identifying a species as either native or exotic. We then identify several of the values that are at stake in dealing with exotic species, and we suggest that policies need to avoid being overly simplistic. (shrink)

‘Pupil voice’ is a movement within state education in England that is associated with democracy, change, participation and the raising of educational standards. While receiving much attention from educators and policy makers, less attention has been paid to the theory behind the concept of pupil voice. An obvious point of theoretical departure is the work of Jürgen Habermas, who over a number of decades has endeavoured to develop a theory of democracy that places strong significance on language, communication and discourse. (...) This paper is an attempt to gauge the usefulness of Habermas’ approach to understanding the theory of pupil voice, in particular how his theory of universal pragmatics lends itself to a ‘philosophy of between’, a philosophy that finds echoes in the conflicted nature of schooling that ‘pupil voice’ is supposed to rectify to some extent. The paper also explores the drawbacks of a Habermasian approach, in particular his overreliance on rationality as a way of understanding communication. Lacan’s concept of the objet petit a is introduced as an alternative way of understanding pupil voice. (shrink)

We extend attribution and stakeholder theory in the context of crisis reputation management by examining differences in stakeholder perceptions in the form of organization-related blame. We presented eight stakeholder groups with factual information surrounding the Deepwater Horizon Oil Spill and asked them to indicate the extent to which they blamed the leaders and organizations associated with the event. Stakeholders also completed a survey assessing their attribution styles. Results indicated that perceptions of blame were affected by the interaction of stakeholder role (...) (i.e., active vs. passive) with attribution style (i.e., optimistic vs. pessimistic). Our results suggest that organizational leaders’ understanding of their stakeholders may be an important aspect in managing stakeholders’ sensemaking during crises. (shrink)

This manuscript overviews recent research on the intention-behavior gap, focusing on moderators of the intention-behavior relationship. The manuscript draws on the concept of intention strength to make two important points. First, strong intentions provide better predictions of behavior, thereby reducing the intention-behavior gap. However, strong intentions have the additional features of being more stable over time, less pliable in the face of interventions to change them, and more likely to bias information processing about engaging in the behavior. These four features (...) of intention strength are not independent. For example, stable intentions are likely to provide better predictions of behavior. Second, various predictors of strength may also constitute important, but little studied, moderators of the intention-behavior relationship. Moreover, the effects of these moderators of the intention-behavior relationship may be mediated through intention stability. Future research on the intention-behavior gap would benefit from a more systematic consideration of a broad range of moderators of the intention-behavior relationship both individually and in combination. In addition, future research could usefully explore how these moderating effects might be explained. Such a systematic approach may further our understanding of the intention-behavior gap in relation to physical activity and other behaviors. (shrink)

In a series of publications beginning in the 1980s, John Etchemendy has argued that the standard semantical account of logical consequence, due in its essentials to Alfred Tarski, is fundamentally mistaken. He argues that, while Tarski's definition requires us to classify the terms of a language as logical or non-logical, no such division is guaranteed to deliver the correct extension of our pre-theoretical or intuitive consequence relation. In addition, and perhaps more importantly, Tarski's account is claimed to be incapable of (...) explaining an essential modal/epistemological feature of consequence, namely, its necessity and apriority. Bernard Bolzano (1781-1848) is widely recognized as having anticipated Tarski's definition in his Wissenschaftslehre (or Theory of Science ) of 1837. Because of the similarities between his account and Tarski's, Etchemendy's arguments have also been extended to cover Bolzano. The purpose of this article is to consider Bolzano's theory in the light of these criticisms. We argue that, due to important differences between Bolzano's and Tarski's theories, Etchemendy's objections do not apply immediately to Bolzano's account of consequence. Moreover, Bolzano's writings contain the elements of a detailed philosophical response to Etchemendy. (shrink)

An excellent introduction to the field of international relations, The Global Philosophers examines the intellectual roots of contemporary literature on international relations and discusses the historical context in which famous historical political theorists wrote.

Belief in substance dualism, the idea that mind and matter are two different kinds of substances, has been found to be a strong predictor of belief in free will. Why? Here, we test whether believing that mind and matter are different kinds of substance correlates with differences in how people think of free will and/or differences in how people interpret the scenarios used to test their conceptions. We provided participants (N = 515) with two hypothetical scenarios where the world was (...) presented either as deterministic or not and asked them whether they thought that a given decision could be free in that world. Incompatibilist free will requires that determinism, the idea that at any instant only one possible future can follow from the state of the world, is false. Compatibilists hold that free will is possible even if determinism is true. In this study, we investigate if substance dualists are more compatibilist. We find that they are not, and that both dualists and physicalists agree that free will is incompatible with determinism. In addition, we show that dualists and physicalists are equally likely to commit bypassing, i.e., to misinterpret determinism as excluding mental causation. We also show that dualists have a stronger tendency to commit intrusion, i.e., to misinterpret determinism by importing indeterministic metaphysics into their interpretation of deterministic descriptions. (shrink)

At almost every election, Americans are inclined to say that this is the most consequential election in American history. 2020 is no exception. However, what is particularly remarkable about the No...

Part 1. FOUNDERS AND FIRSTCOMERS1: David Zimmerman: 'Protests Butter no Parsnips': Lord Beveridge and the Rescue of Refugee Academics from Europe, 1933-19382: William Lanouette: A Narrow Margin of Hope: Leo Szilard in the Founding Days of CARA3: Paul Weindling: From Refugee Assistance to Freedom of Learning: the Strategic Vision of A. V. Hill, 1933-19644: Gustav Born: Refugee Scientists in a New Environment5: Georgina Ferry: Max Perutz and the SPSLPART 2. TESS - THE LINCHPIN6: Paul Broda: Esther Simpson: A (...) Correspondence7: Lewis Elton: Eva and EstherPART 3. ASSOCIATES AND ALLIES8: Gerald Kreft: 'Dedicated to Represent the True Spirit of the German Nation in the World': Philipp Schwartz, Founder of the Notgemeinschaft9: Tibor Frank: Organized Rescue Operations in Europe and the United States, 1933-194510: Susan Cohen: In Defence of Academic Women Refugees: The British Federation of University Women11: Stina Lyon: Karl Mannheim and Viola Klein: Refugee Sociologists in Search of Social Democratic PracticePART 4. REVERSING THE GAZE12: Christian Fleck: Austrian Refugee Social Scientists13: Antoon de Baets: Plutarch's Thesis: The Contribution of Refugee Historians to Historical Writing, 1945-201014: Marina Yu Sorokina: Within Two Tyrannies: The Soviet Academic Refugees of the Second World War15: Antonín Kostlán and Soña Strbáñová: Czech Scholars in Exile, 1948-198916: Shula Marks: 'Bending the rules': South African Refugees in the UK, 1960-198017: Alan Phillips: Refugee Academics from Chile: WUS-SPSL CollaborationLucia Muñoz: Postscript. (shrink)

The COVID-19 pandemic has raised a host of ethical challenges, but key among these has been the possibility that health care systems might need to ration scarce critical care resources. Rationing p...

There is a presumption that it is the philosophers who know the truth, and the business people who need to be told it. However, business is a unique phenomenon. At no time in human history has anything quite like this been seen before. Unreflective or no, crises or no, poverty or no, something works in this system.

There is a presumption that it is the philosophers who know the truth, and the business people who need to be told it. However, business is a unique phenomenon. At no time in human history has anything quite like this been seen before. Unreflective or no, crises or no, poverty or no, something works in this system.

In the last decade, experimental philosophers have documented systematic asymmetries in the attributions of mental attitudes to agents who produce different types of side effects. We argue that this effect is driven not simply by the violation of a norm, but by salient-norm violation. As evidence for this hypothesis, we present two new studies in which two conflicting norms are present, and one or both of them is raised to salience. Expanding one’s view to these additional cases presents, we argue, (...) a fuller conception of the side-effect effect, which can be reversed by reversing which norm is salient. (shrink)

The research was conducted using the Advanced search function of the European Patent Office esp@cenet “worldwide” database. In making the dataset available in an open access journal our aim is to encourage greater research and data sharing on intellectual property and biodiversity. On that basis the sole condition of use is attribution of authorship. Excel files are available from the authors upon request.

This work tests two conflicting views about double standards: whether they reflect evolved sex differences in behavior or a manipulative morality serving male interests. Two questionnaires on jealous reactions to mild (flirting) and serious (cheating) sexual transgressions were randomly assigned to 172 young women and men. One questionnaire assessed standards for appropriate behavior and perceptions of how young women and men usually react. The second asked people to report how they had reacted or, if naive, how they would react. The (...) questions concerned anger at and blame of partner and rival and the self-oriented responses of loss of self-esteem, feelings of hurt, and fear of losing the partner. As predicted by the idea of manipulative morality, both sexes advanced sets of double standards that serve the interests of their own sex at the expense of the opposite sex. Much of the data contradict the idea of a match between double standards and evolved sex differences. First, subjects who set self-serving double standards did not perceive gender differences in jealous reactions. Second, there were few gender differences in judgments regarding jealous responses. Third, in contrast with the familiar double standard, women were more aggressively reactive to a flirting rival than men. Fourth, self-reports of the strength of aggressive jealous reactions suggest that women’s behavior is stronger than the prescriptions for it. These data suggest that double standards represent a communication strategy which assists men’s control of women. The data on jealous reactions were interpreted in terms of the degree of threat to fitness posed by infidelity in different situations. (shrink)

Issues of interest, identity and values intertwine in environmental conflicts, creating challenges that cannot generally be overcome using rationalities grounded in generalised argumentation and abstraction. To address the growing need to engage interests and identities along with plural values in the conservation of biodiversity and ecological systems, we introduce the concept of ‘appropriateness of actions’ and ground it in a relational understanding of environmental ethics. A determination of appropriateness for actions comes from combining outputs from value elicitation with those of (...) interest and identity negotiation in ways that are salient to specific people and their relationships to specific places. Drawing on the Blue Mountain Forest Partnership in the Pacific Northwest, we propose factors of success for supporting appropriate actions: 1) understanding context and identifying key stakeholders; 2) surfacing a diversity of interests and building system-level trust; 3) building empathy for different identities grounded in specific places; 4) eliciting diverse values and seeking to understand their links to worldviews and knowledge systems and; 5) seeking out appropriate actions. (shrink)

Recent findings in experimental philosophy have revealed that people attribute intentionality, belief, desire, knowledge, and blame asymmetrically to side- effects depending on whether the agent who produces the side-effect violates or adheres to a norm. Although the original (and still common) test for this effect involved a chairman helping or harming the environment, hardly any of these findings have been applied to business ethics. We review what little exploration of the implications for business ethics has been done. Then, we present (...) new experimental results that expand the attribution asymmetry to virtue and vice. We also examine whether it matters to people that an effect was produced as a primary or side- effect, as well as how consumer habits might be affected by this phenomenon. These results lead to the conclusion that it appears to be in a businessperson’s self-interest to be virtuous. (shrink)

I will discuss two themes that can be found in Mark Sagoff's most recent book, Price, Principle, and the Environment. Built from pieces fashioned in his entertaining and incisive critical es...