RNA localization is a powerful strategy used by cells to localize proteins to subcellular domains and to control protein synthesis regionally. In germ cells, RNA targeting has profound implications for development, setting up polarities in genetic information that drive cell fate during embryogenesis. The frog oocyte offers a useful system for studying the mechanism of RNA localization. Here, we discuss critically the process of RNA localization during frog oogenesis. Three major pathways have been identified that are temporally and spatially separated (...) in oogenesis. Each pathway uses a different mechanism to effect RNA localization. In some cases, localization elements within the 3' untranslated region have been identified and have provided unique insights into the localization process. This important field is still in its infancy, however, and much remains to be learned. BioEssays 21:546–557, 1999. © 1999 John Wiley & Sons, Inc. (shrink)

This paper focuses on the ethical and moral implications of findings from the authors? national survey of television news directors? policies, practices, and perceptions of good/bad news. In light of the potentially negative effects of excessive amounts of bad news on individuals and society, the authors ask whether television journalists have an ethical responsibility?beyond legal constraints and professional criteria?in the selection and presentation of bad news and good news. An earlier version of this paper, detailing the findings of the survey, (...) was presented to the Radio?TV Journalism Division of the Association for Education in Journalism and Mass Communication in August, 1986. (shrink)

Abstract‘Cruel optimism’ is a term coined by Lauren Berlant. In conceptualizing this term, Berlant draws on the resources of critical theory to interrogate people’s desires for things they think may improve their lot, but actually act as obstacles to flourishing. This notion may be useful for analysing the current state of education in Australia, and the desire to believe that My School, and the associated data it provides, will enable schools to address social inequalities. For Berlant, the promise of such (...) technologies is problematic because it diverts our attention from important ethical, social and political questions, some of which are highlighted in the contributions to this special issue. Using ‘cruel optimism’ as a point of departure, I interrogate how the notion of critical theory has been conceptualized in educational research by briefly looking at scholarship within and outside education relating to critical theory. Following on from this, I consider how what I am terming critical theory is put to work in each of the articles that make up this special issue on My School. (shrink)

This book engages contemporary debates about the notion of secularism outside of the field of education in order to consider how secularism shapes the formation of progressive sexuality education. Focusing on the US, Canada, Ireland, Aotearoa-New Zealand and Australia, this text considers the affinities, prejudices, and attachments of scholars who advocate secular worldviews in the context of sexuality education, and some of the consequences that ensue from these ways of seeing. This study identifies and interrogates how secularism infuses progressive sexuality (...) education. It asks readers to consider their own investments in particular ways of thinking and researching in the field of sexuality education, and to think about how these investments have developed and how they shape existing discourses within the field of sexuality education. It hones in on how progressive sexuality education has come to develop in the way that it has, and how this relates to conceits of secularism. This book prompts a consideration of how "progressive" scholarship and practice might get in the way of meaningful conversations with students, teachers, and peers who think differently about the field of sexuality education. (shrink)

If ‘a’ and‘b’are (proper) names and if the meaning of a name is exhausted by its referent, how can‘a = a’differ in cognitive value from‘a = b’if‘a = b’is true? This is Frege's famous puzzle and Bezuidenhout reconstructs it using demonstrative NPs in place of names, i.e.: This X is that X.’Her solution is to posit the‘truth-conditional relevance’of the de re modes of presentation of such expressions. My major objection is that Bezuidenhout's examples are such that the NP to the (...) right of the copula is anaphoric rather than demonstrative and cannot, therefore, support her argument. (shrink)

To find more information on Rowman & Littlefield titles, please visit us at www.rowmanlittlefield.com.

To find more information on Rowman & Littlefield titles, please visit us at www.rowmanlittlefield.com.

In the next few years, biotechnology will continue to develop a wide variety of functional foods, foods whose benefits go well beyond basic nutrition. Minors are a major potential market for bioengineered foods that are promoted not as sustaining health but rather as supporting desired lifestyles through the enhancement of physical, athletic, intellectual, or social performance. The experience of other industries suggests that such biomarketing is likely to create a variety of highly public ethical controversies. After a discussion of some (...) of these potential issues, suggestions on how companies and industries can work with marketing ethicists and child advocates to limitnegative impacts on children and youth are presented. That discussion includes a preliminarily analysis of some of the considerations that should be involved in the initial development of a model of biomarketing ethics and in the use of that model to prevent ethical abuses. (shrink)

_The Cultural Politics of Queer Theory in Education Research_ represents the editors’ intention to disrupt cycles of thinking about the place of queer theory in educational research. The book aims to encourage dialogue about the objects and subjects of queer research, the forms of politics incited by the use of queer theory in education, and the methodological approaches used by scholars when queering. The contributions to this book come from those who find queer theory problematic, as well as from those (...) who continue to see a productive place for queer research in education, however that may be defined. The editors have collected contributions that attend to the boundaries that are placed around queer research in education by researchers themselves, and by peers, ethics committees, funding bodies and university and government bureaucracies. Considering how key researchers in gender and education identify with, or deliberately distance themselves from, queer theory, this collection grapples with the contemporary cultural politics of doing queer theoretical work in different education spaces and places. In short, it seeks to disrupt what people think they already know about the ‘place’ of queer theory in education. This book was originally published as a special issue of _Discourse: Studies in the Cultural Politics of Education. _. (shrink)

Teaching in university education programmes, can, at times, involve the uncomfortable situation of discriminatory speech.A situation that has often occurred in our own teaching, and in those of our colleagues, is the citation of homophobic and heterosexist comments.These are comments that are more likely to occur in foundation subjects such as philosophy and sociology of education.The occurrence of such situations has prompted debate regarding ‘silencing words that wound’. This has prompted the question, ‘should we keep students from stating such discriminatory (...) speech?’ Our article takes up this issue, and considers it from the perspective of the importance of critique.Working with Foucault’s What is Critique? together with his discussion of subjectivation in the 1981–82 lectures at the Collège de France, we set out to make the case for the significance of the relationship between truth and critique.This leads us to a position where we ask the question, if we silence, what do we risk doing to critique? (shrink)

Ce texte s’inscrit dans le prolongement d’un effort endurci pour penser les modalités complexes du dialogue entre la psychanalyse lacanienne et la phénoménologie française dans la seconde moitié du xx e siècle. Plus exactement, il s’agit ici d’indiquer les raisons objectives, à la fois théoriques et pratiques, qui expliquent la violence de la réception française du De l’interprétation de Paul Ricœur, en mettant en perspective les positions respectives du philosophe et celles du psychanalyste Jacques Lacan lors du colloque de Bonneval (...) sur l’Inconscient d’octobre 1960. L’analyse détaillée du texte “Le conscient et l’inconscient” – élément du corpus ricœurien trop souvent négligé – au regard de l’enseignement lacanien du tournant des années 1960 doit en outre permettre de dégager deux théories de l’interprétation antagonistes, afin d’indiquer pour finir les points concrets de divergence entre les orientations “ricœurienne” et “lacanienne” de la clinique psychanalytique. (shrink)

Working memory deficits are pervasive co-morbidities of epilepsy. Although the pathophysiological mechanisms underpinning these impairments remain elusive, it is thought that WM depends on oscillatory interactions within and between nodes of large-scale functional networks. These include the hippocampus and default mode network as well as the prefrontal cortex and frontoparietal central executive network. Here, we review the functional roles of neural oscillations in subserving WM and the putative mechanisms by which epilepsy disrupts normative activity, leading to aberrant oscillatory signatures. We (...) highlight the particular role of interictal epileptic activity, including interictal epileptiform discharges and high frequency oscillations in WM deficits. We also discuss the translational opportunities presented by greater understanding of the oscillatory basis of WM function and dysfunction in epilepsy, including potential targets for neuromodulation. (shrink)

This paper explores violence in intimate relationships in one low-income community in the Western Cape, South Africa. In this community most intimate relationships (including parentchild, intimate partner relationships and friendships) seem to be characterized by anger, rage and also violence. In our analysis we discuss how the concepts of shame, guilt and the compulsion to repeat can serve to illuminate the seemingly inevitable link between violence and care in this specific community. It also seems that contextual factors such as class, (...) gender and race shape not only the form violence assumes, but also to whom it is directed. While we pay attention to the material and ideological conditions that shape the lives of individual storytellers, we also focus on the ways in which violence is represented in the individual stories. (shrink)

Cet article constitue la présentation des recherches effectuées par une équipe franco-grecque sur le tell de Kirrha en Phocide entre 2008 et 2015, et représente la publication préliminaire des structures archéologiques mises au jour. Deux secteurs distants l’un de l’autre ont été fouillés, révélant une dense occupation de l’Helladique Moyen, ainsi que des niveaux s’étageant jusqu’à l’Helladique Récent III. Notamment, une nécropole de la période transitionnelle (Helladique Moyen III – Helladique Récent I/II) a été fouillée dans la partie occidentale du (...) site, tandis que des niveaux mycéniens ont été reconnus à proximité du sommet. (shrink)

Combining textual, visual, and ethnographic approaches to discourse, this article examines a variety of resources employed in the narrative construction of Washington, DC’s Chinatown in a billboard advertisement that de-ethnicizes the neighborhood. Analysis of the linguistic resources of narrative structure, comparative reference, and lexical cohesion reveals how the gentrification of Chinatown is constructed as a positive transformation driven by a corporation. Further, the visual juxtaposition of text with photos and graphics appropriates the community voice and infuses it with corporate identity. (...) This ideological multimodal construction of the transformation of Chinatown is finally actualized in its durable material form and strategic spatial emplacement. Incorporating ethnographic observation and an interview, this article illustrates how the symbolic power of narrative in place-making is interdependent on the economic power of its producer to propagate ideological discourse in the material world. (shrink)

This selection consists of extracts from writings of women concerned solely with the pursuit of abstract ideas, historically contextualized. The texts, for the most part, reflect issues widely debated in their contemporary societies. Extracts from lesser-known writers are also included, providing a diversity of arguments spanning four centuries and including some notable contemporary philosophers.

A leader in the modern commentary on ethics and philosophy, Mary Warnock casts a critical eye over her life and times.

The distinction between “empathy” and “sympathy” in the context of ethics is a dynamic and challenging one. The eighteenth century texts of David Hume and Adam Smith used the word "sympathy," but not "empathy," although the conceptual distinction marked by empathy was doing essential work in their writings. After discussing the early uses of these terms, this article is organized historically. Two traditions are distinguished. The first is the Anglo-American tradition, and it extends from Hume and Smith to the twenty-first (...) century work of Michael Slote. Stephen Darwall’s contribution is applied in engaging Hume and Smith. Finally, the interrelation of empathy, sympathy and altruism is explored in the work of John Rawls and Thomas Nagel. The second tradition is the Continental one. It extends from the spirituality of Johann Herder to the phenomenological movement of Edmund Husserl, Martin Heidegger, Max Scheler, and Edith Stein. The intentional analysis of empathy is directly relevant to the constitution of the social community in a broad, normative relationship with the "Other.". (shrink)

How is hope to be found amid the ethical and political dilemmas of modern life? Writer and philosopher Mary Zournazi brought her questions to some of the most thoughtful intellectuals at work today. She discusses "joyful revolt" with Julia Kristeva, the idea of "the rest of the world" with Gayatri Spivak, the "art of living" with Michel Serres, the "carnival of the senses" with Michael Taussig, the relation of hope to passion and to politics with Chantal Mouffe and Ernesto Laclau. (...) A dozen stimulating minds weigh in with their visions of a better social and political order. The result is a collaboration - of writing, of thinking, and of politics - that demonstrates more clearly than any single-authored project could how ideas encountering one another can produce the vision needed for social change. (shrink)

L’infléchissement de l’économie vers la scientificité masque un paradoxe : moins l’économie s’annonce comme politique, plus elle l’est. L’approche critique de Marx rappelle en effet combien ce régime de discours est idéologique. Réciproquement, c’est le dépassement politique, indexé au matérialisme historique, qui donne à la critique marxienne sa fécondité heuristique. Celle-ci s’appuie sur un projet : l’appropriation politique des forces productives. Définissant ces trois sens dans la lecture de Marx mais aussi dans la distance qui nous en sépare, l’étude s’interroge (...) sur une question posée au présent : comment gagner en politicité? (shrink)

All religion and much philosophy has been concerned with the contrast between the ephemeral and the eternal. Human beings have always sought ways to overcome time, and to prove that death is not the end. This book consists then in an exploration of certain closely related ideas: personal identity, time, history and our commitment to the future, and the role of imagination in life.

En este libro, la autora desarrolla su concepción del juicio reflexionante inspirada en Emmanuel Kant y en Hannah Arendt para concentrarse en cómo cierto tipo de narraciones modelan nuestras nociones de lo que consideramos moral. Lara nos ofrece distintas concepciones sobre el mal en su formulación histórica mediante los ejemplos de las tragedias griegas, las diferentes concepciones sobre el mal en la obra de Shakespeare, el uso literario de la metáfora en la obra de Joseph Conrad y en narraciones fílmicas (...) que describen la crueldad humana. Lara sugiere que el aprendizaje moral es un proceso en el que intervienen las instituciones sociales, la voluntad de los individuos y de las sociedades para comprometerse a un debate abierto y con ello modelar los juicios colectivos sobre el pasado. Lara enfatiza que el juicio reflexionante se da entre un evento, una narración de dicho evento y la recepción pública de dicha narrativa. En este libro se aportan importantes métodos para la comprensión del fenómeno moral del mal, porque introducen nuevas verdades desvelatorias acerca de eventos particulares que no pueden ser simplemente captados por medio de categorías conceptuales. Lara utiliza como fuentes a Jürgen Habermas, Walter Benjamin, Primo Levi, Giorgio Agamben y Ariel Dorfman para probar la conclusión de este tipo de narraciones: la acción (de crueldad) ata de manera definitiva al perpetrador con su víctima. (shrink)

Fundamental principles : the nature of the dispute -- Types of euthanasia -- Psychiatric assisted suicide -- Neonates -- Incompetent adults -- Human life is sacred -- The slippery slope -- Medical views -- Four methods of easing death and their effect on doctors -- Looking further ahead.

Let T be a complete o-minimal extension of the theory of real closed fields. We characterize the convex hulls of elementary substructures of models of T and show that the residue field of such a convex hull has a natural expansion to a model of T. We give a quantifier elimination relative to T for the theory of pairs (R, V) where $\mathscr{R} \models T$ and V ≠ R is the convex hull of an elementary substructure of R. We deduce (...) that the theory of such pairs is complete and weakly o-minimal. We also give a quantifier elimination relative to T for the theory of pairs (R, N) with R a model of T and N a proper elementary substructure that is Dedekind complete in R. We deduce that the theory of such "tame" pairs is complete. (shrink)

The works of Mary Wollstonecraft (1759-1797) ranged from the early _Thoughts on the Education of Daughters_ to _The Female Reader_, a selection of texts for girls, and included two novels. But her reputation is founded on _A Vindication of the Rights of Woman_ of 1792. This treatise is the first great document of feminism—and is now accepted as a core text in western tradition. It is not widely known that the germ of Wollstonecraft’s great work came out of an earlier (...) and much shorter vindication—A Vindication of the Rights of Men (1790), written in the context of the issues raised by the French Revolution. This edition, which follows the model of other Broadview Editions in including a range of materials that help the reader to see the work in the context of its era out of which it emerged, is arranged chronologically, opening with Wollstonecraft’s “other vindication.” It also includes a wide range of other documents in appendices, as well as a comprehensive and authoritative introduction, chronology, and full index. (shrink)

On the face of it, normative conflicts are commonplace. Yet standard deontic logic declares them to be logically impossible. That prompts the question, What are the proper principles of normative reasoning if such conflicts are possible? This paper examines several alternatives that have been proposed for a logic of 'ought' that can accommodate normative conflicts, and finds all of them unsatisfactory as measured against three criteria of adequacy. It then introduces a new logic that does meet all three criteria, and (...) so allows for the possibility of genuine normative conflicts. (shrink)

I solve here some problems left open in “T-convexity and Tame Extensions” [9]. Familiarity with [9] is assumed, and I will freely use its notations. In particular,Twill denote a completeo-minimal theory extending RCF, the theory of real closed fields. Let (,V) ⊨Tconvex, let=V/m(V)be the residue field, with residue class mapx↦:V↦, and let υ:→ Γ be the associated valuation. “Definable” will mean “definable with parameters”.The main goal of this article is to determine the structure induced by(,V)on its residue fieldand on its (...) value group Γ. In [9] we expanded the ordered fieldto a model ofTas follows. Take a tame elementary substructure′ ofsuch thatR′ ⊆VandR′maps bijectively ontounder the residue class map, and make this bijection into an isomorphism′ ≌ofT-models. (We showed such′ exists, and that this gives an expansion ofto aT-model that is independent of the choice of′.). (shrink)