Cancer chemotherapy has been the most common cancer treatment. However, it has side effects that kill both tumor cells and immune cells, which can ravage the patient’s immune system. Chemotherapy should be administered depending on the patient’s immunity as well as the level of cancer cells. Thus, we need to design an efficient treatment protocol. In this work, we study a feedback control problem of tumor-immune system to design an optimal chemotherapy strategy. For this, we first propose a mathematical model (...) of tumor-immune interactions and conduct stability analysis of two equilibria. Next, the feedback control is found by solving the Hamilton–Jacobi–Bellman equation. Here, we use an upwind finite-difference method for a numerical approximate solution of the HJB equation. Numerical simulations show that the feedback control can help determine the treatment protocol of chemotherapy for tumor and immune cells depending on the side effects. (shrink)

세계경제의 시대별 변천과정, 우리나라의 경제성장 및 발전과정을 살피고 한국 기업의 역할 및 기여를 규범적으로 평가하여 경제 후유증 및 부작용의 원인 을 살폈다.

Charles Taylor is one of the most distinctive figures in the landscape of contemporary philosophy. His ability to contribute to philosophical conversations across a wide spectrum of ideas is especially impressive in a time of increasing specialization. These areas include moral theory, theories of subjectivity, political theory, epistemology, hermeneutics, philosophy of mind, philosophy of language and aesthetics. Most recently, Taylor has branched into the study of religion. Written by a team of international authorities, this collection will be read primarily by (...) students and academic professionals in philosophy, political science, and religious studies, and will also appeal to a broad swathe of professionals across the humanities and social sciences. Ruth Abbey is Senior Lecturer in Political Theory at University of Kent at Canterbury. She has published numerous articles and is author of Nietzsche's Middle Period (Oxford University Press, 2000) and Philosophy Now: Charles Taylor (Princeton University Press, 2000). (shrink)

Ng :255–285, 1995. https://doi.org/10.1007/bf00852469) models the evolutionary dynamics underlying the existence of suffering and enjoyment and concludes that there is likely to be more suffering than enjoyment in nature. In this paper, we find an error in Ng’s model that, when fixed, negates the original conclusion. Instead, the model offers only ambiguity as to whether suffering or enjoyment predominates in nature. We illustrate the dynamics around suffering and enjoyment with the most plausible parameters. In our illustration, we find surprising results: (...) the rate of failure to reproduce can improve or worsen average welfare depending on other characteristics of a species. Our illustration suggests that for organisms with more intense conscious experiences, the balance of enjoyment and suffering may lean more toward suffering. We offer some suggestions for empirical study of wild animal welfare. We conclude by noting that recent writings on wild animal welfare should be revised based on this correction to have a somewhat less pessimistic view of nature. (shrink)

Intergenerational impartiality requires putting the welfare of future generations at par with that of our own. However, rational choice requires weighting all welfare values by the respective probabilities of realization. As the risk of non-survival of mankind is strictly positive for all time periods and as the probability of non-survival is cumulative, the probability weights operate like discount factors, though justified on a morally justifiable and completely different ground. Impartial intertemporal welfare maximization is acceptable, though the welfare of people in (...) the very far future has lower effects as the probabilities of their existence are also lower. However, the effective discount rate on future welfare values justified on this ground is likely to be less than 0.1 per annum. Such discounting does not compromise environmental protection and sustainability unduly. The finiteness of our universe implies that the sum of our expected welfare to infinity remains finite, solving the paradox of having to compare different infinite values in optimal growth/conservation theories. (shrink)

本書係針對歐陸哲學中，現代與後現代對主體的爭議進行比較研究，並引申其教育涵義。共探討了笛卡爾、康德、黑格爾、結構主義、海德格、傅科及後現代對於人的自我定位之差異，提供了哲學上對人的各種假設。人從現代主 體的地位逐漸轉變成了後現代各式各樣的多元認同。 在教育上，因著各種對人的定位方式而有不同的教育模式。本書從自我成長和認同的角度來引申以上每個哲學家或主義的教育觀點。最後，探討台灣在二次戰後人們在認同上的重大轉變及今日所面臨的認同困境。也說明了今天在 教育上所要面對的任務.

本书从中国古代宗教及儒释道三家的学说中,发掘有关人生修养及道德教育方面的思想,对于了解和继承优秀的传统文化、建设新时期精神文明和道德文化具有借鉴和启发意义。.

Olwen Bedford and Kwang-Kuo Hwang, Guilt and Shame in Chinese Culture: A Cross-cultural Framework from the Perspective of Morality and Identity, pp. 127–144.This article formulates a cross-cultural framework for understanding guilt and shame based on a conceptualization of identity and morality in Western and Confucian cultures. First, identity is examined in each culture, and then the relation between identity and morality illuminated. The role of guilt and shame in upholding the boundaries of identity and enforcing the constraints of morality (...) is then discussed from the perspective of each culture. The developed framework is then applied the emotions of guilt and shame in Chinese culture drawing on previous field research. Implications for future research are discussed. (shrink)

The goal of this article is attempting to establish a research tradition of Chinese relationalism on the methodological grounds of constructive realism. Two of Ho’s key concepts, person-in-relations and persons-in-relation, are carefully examined and reinterpreted. Three of my theoretical models, namely, my Face and Favor model , Confucian ethics for ordinary people , and a conflict resolution model , are conceived of as microworlds for illustrating an account of person-in relations in Chinese culture. The manifestation of Confucian ethics for ordinary (...) people in one’s lifeworld results in the phenomenology of persons-in-relations as depicted by Fei’s differential order or Hsu’s psychosociogram. Applying constructive realism to my models and using the result as a framework for studying Chinese social behavior constitutes Chinese relationalism. (shrink)

도교의 이론적 근거를 제공한 노장.도가사상의 기원 과 원리를 집중 고찰한 저서.

This paper investigates whether the pattern of firms’ corporate social responsibility activities affects firm value. If firms do permanently CSR activities for strategic purposes, firms’ value is more likely to increase. Using firms known to do CSR in Korea, we examine the valuation effect by adopting an earnings response coefficient model and document firms with permanent CSR activities, which show higher ERCs than other firms regardless of the level of CSR activities. This result partly explains the inconsistency among the results (...) of previous studies by showing the differential implication for firm value depending on the CSR activity pattern. Also, the results of our paper imply that investors need to consider the pattern of firms’ CSR activities in their economic decision making. (shrink)

本书着力从现象学美学的方法论特征入手,系统地研究了胡塞尔、海德格尔、萨特、梅洛-庞蒂、茵加登及杜夫海纳等人的美学思想,以及他们在艺术、审美问题上的不同观点。.