The peer commentaries on our Target Article, “Promoting Ethical Payment in Human Infection Challenge Studies,” offer a number of insights that will help advance the co...

To prepare for potential human infection challenge studies involving SARS-CoV-2, we convened a multidisciplinary working group to address ethical questions regarding whether and how much SAR...

Temporal experience and its radical alteration in schizophrenia have been one of the central objects of investigation in phenomenological psychopathology. Various phenomenologically oriented researchers have argued that the change in the mode of temporal experience present in schizophrenia can foreground its psychotic symptoms of delusion. This paper aims to further the development of such a phenomenological investigation by highlighting a much-neglected aspect of schizophrenic temporal experience, i.e., its non-emotional affective characteristic. In this paper, it denotes the type of an experience (...) wherein an afflicted individual experiences a pervasive pull or attraction coming from the past, present, and future. By employing Husserl’s account of affection, I argue that such an affectively prominent temporal experience is not yet another abnormality that happens to be present in schizophrenia. Instead, it is indicative of the core disturbance that underpins the schizophrenic temporal mode of experience. I identify such a disturbance as ‘affective modification dysfunction’ and employ it as a core concept with which I synthesize and organise heterogeneous components of schizophrenic temporal experience in their conceptual unity. For the sake of clear description, I organise those components into the following categories: 1.) Time Stop 2.) Ante-festum 3.) Déjà vu/vécu and 4.) Time Fragmentation. I conclude by demonstrating how approaching schizophrenic temporal experience from its affective dimension can further help us better understand its pre-psychotic phase known to precipitate schizophrenic primary delusion, i.e., delusional mood. (shrink)

This article examines how growing fears, insecurities and uncertainties during the COVID-19 pandemic have prompted an emotional distance from others. The aim is to explore how global solidarity and nationalism are challenged and constructed as collective emotional processes concerning ‘others’. Drawing on social theories of emotions during crises and emotions towards others, this study looks at policy decisions around vaccines and health services and their associated emotions in the context of Korea, which has a relatively small migrant population and a (...) short history of supporting people in lower-income countries. The study finds that the COVID-19 pandemic has strengthened nationalism, both ethnic nationalism and cosmopolitan nationalism. This points to the need to highlight global norms such as human rights and justice and cultivate foundational emotions such as empathy and compassion. This article suggests paying attention to the role of emotions in generating othering practices and developing global solidarity. (shrink)

Être transgenre implique des relations uniques à son propre corps, ainsi que la question du récit dans la formation du sujet – deux thèmes-clés chez Merleau-Ponty. Mais même si l’on accepte d’aller au-delà de l’histoire stéréotypée d’être « pris·e dans le mauvais corps », tant dans les communautés trans que dans le discours public plus large il existe une tendance fâcheuse à universaliser de tels récits – et ce, en dépit de l’hétérogénéité apparente que l’on retrouve dans les descriptions individuelles (...) à la première personne. La question émerge donc à savoir : comment rendre compte philosophiquement de cette différence à la première personne tout en visant une politique de solidarité? Cet essai cherche à utiliser la phénoménologie de Merleau-Ponty dans un sens pratique, en se concentrant sur sa description du « schéma corporel » pour atténuer cette tension. En effet, tandis que Merleau-Ponty nous fournit un ensemble général d’instruments pour comprendre la relation entre incarnation et comportement, ses exemples phénoménologiques sont souvent fortement singuliers. De la sorte, dans le contexte des subjectivités transgenres, le but est de creuser davantage cet espace discursif, comme prologue pour une praxis qui soit plus réceptive à l’expérience vécue des personnes trans. (shrink)

Asian workplaces are often characterized by cultures that require more overtime than other cultures. Although predictors for overtime work have been rigorously studied, it is still meaningful to investigate specific aspects of Eastern cultural values that stem from Confucian ethics and may influence overtime work among Asian employees. We suggest that four major Confucian orientations are positively associated with employees’ affective and normative motives, which in turn affect working overtime. This article extends management literature on the subjects of cultural ethics (...) and workaholism. It also suggests how Eastern cultural values lead to working overtime. We hope that our research effort on Confucian cultural value and its associations with other managerial outcomes and theories is a small cornerstone that allows management researchers to explore interesting and meaningful ways to apply Confucian culture and orientations in the workplace. (shrink)

In light of the ongoing validity crisis in psychiatric classification, phenomenologically oriented psychiatric study has gained traction. This paper assesses two modes of investigation proposed by phenomenologists in studying mental disorders: the ideal type approach and the essential type approach. Despite the recent suggestion that they are antithetical approaches, I argue that they should constantly constrain and inform each other. In short, I advance a mutual complementarity thesis. Having established this thesis, I conclude by demonstrating how this proposal can function (...) as an heuristic strategy for effectively facilitating the recently proposed psychiatric research initiative, i.e. the ontological project of phenomenological psychopathology. (shrink)

INTRODUCTION JEAN-MICHEL GANTEAU AND SUSANA ONEGA The rise of trauma theory in the critical field is a recent phenomenon associated with the revival of ...

It is often taken for granted that Paul Hirst’s switch from emphasis on liberal education to a social practices view of education is a radical one. This depends on how we understand the relation between the two views. From the perspective of a ‘weak’ interpretation I argue that Hirst’s later position differs little from his earlier one in the light both of the relation between the forms of knowledge and social practices, and of the rationalistic character of Hirst’s conception of (...) social practices in their connection with education. (shrink)

This paper investigates why some legislators tend to switch parties frequently while others tend to stay put. On the assumption that the ultimate goal of legislators is to be reelected, I argue that voters' demands for local/individual benefits, or pork, and legislators' lack of access to resources for such benefits are likely to lead the legislators to switch parties in order to improve their electoral chances in the subsequent election. By analyzing party switches by legislators from 1988 to 2008 in (...) South Korea, where the president controls access to the pork pipeline, I find that the president's party members are less likely and independents are more likely to change party affiliations, irrespective of voter demands for pork or national public policies. However, I also find that opposition party legislators who are elected from less-developed districts, where voters tend to desire pork over policy, are more likely to switch parties than those elected from more-developed districts. These findings suggest that interaction between voter demands and party access to resources influences politicians’ party loyalty: voter demands for pork (or policy) tend to lead politicians to be less (or more) loyal to their current parties. Voter demands, however, have little impact on the party loyalty of those who are already in parties with access to the pork pipeline. (shrink)

This research was focused on investigating why some consumers might support cause-related marketing campaigns for reasons other than personal benefit by examining the influence of moral emotions and cultural orientation. The authors investigated the extent to which moral emotions operate differently across a cultural variable (US versus Korea) and an individual difference variable (self-construal). A survey method was utilised. Data were collected from a convenience sample of US ( n = 180) and Korean ( n = 191) undergraduates. Moral emotions (...) significantly influenced purchase intention for a social-cause product. The influence of an ego-focused moral emotion (i.e., pride) on purchase intention was greater for US than Korean participants. The influence of another-focused moral emotion (i.e., guilt) on purchase intention was greater for high-interdependent participants than for low-interdependent participants. The findings of this research provide important and relevant implications to marketers and policy makers in developing persuasive messages and customer relationship programmes. (shrink)

Clinical success with human hematopoietic stem cell (HSC) transplantation establishes a paradigm for regenerative therapies with other types of stem cells. However, it remains generally challenging to therapeutically treat tissues after engineering of stem cells in vitro. Recent studies suggest that stem and progenitor cells sense physical features of their niches. Here, we review biophysical contributions to lineage decisions, maturation, and trafficking of blood and immune cells. Polarized cellular contractility and nuclear rheology are separately shown to be functional markers of (...) a hematopoietic hierarchy that predict the ability of a lineage to traffic in and out of the bone marrow niche. These biophysical determinants are regulated by a set of structural molecules, including cytoplasmic myosin‐II and nuclear lamins, which themselves are modulated by a diverse range of transcriptional and post‐translational mechanisms. Small molecules that target these mechanobiological circuits, along with novel bioengineering methods, could prove broadly useful in programming blood and immune cells for therapies ranging from blood transfusions to immune attack of tumors. (shrink)

SCIENCE CHAPTER I THE CHANGING PATTERN § i THE case presented in this book is not likely to survive criticism in every detail. There never was and there ...

La masificación del ser humano, la conversión del hombre en masa ha sido el acontecimiento más pavoroso de la Edad Contemporánea. Sin embargo, seguimos sin prestar a ese acontecimiento toda la atención que merece. Este libro intenta responder a una serie de preguntas. Preguntas que son de vital importancia porque nos va en ellas la vida como personas y como sociedad civilizada. ¿Qué es un hombre masa? ¿Cómo y cuándo surgió este tipo de hombre? ¿Por qué el hombre masa ha (...) alcanzado tanto poder en el mundo? ¿Qué futuro aguarda a una humanidad masificada? Pedro Jaén nacido en Fernán Núñez (Córdoba) en 1954 ha tenido una formación autodidacta. Ha trabajado como maestro de enseñanza primaria y actualmente está jubilado. Como escritor, alterna el ensayo con la poesía. (shrink)

노화 현상은 생명이나 죽음과 달리 그간 철학적 관심의 대상이 되지 못 했다. 본 연구는 논화 현상에 대한 철학적 접근을 시도하기 위해서, 현대 과학의 성과에 기반하여 노화가 생명체에게 어떤 의미가 있는지를 고찰해보고자 한다. 우선 노화는 물리적 마모 현상이 아님을 지적하고, 노화를 설명하기 위해 생명체가 가진 고유한 안정성의 성격이 무엇인지를 밝히기 위해 슈뢰딩거의 생명 이론, 비평형 열역학의 소산 구조 이론 등을 검토할 것이다. 이 이론들은 생명체가 자신의 손상을 복구하는 고유한 기제를 갖고 있다는 점에 충분히 주의를 기울이지 않았다는 점에서 한계가 있다. 이 손상 (...) 복구 기제에 주목하여 노화를 설명하고자 한 싱클레어의 정보 이론은 노화가 생명체의 현재 자기와 미래 자기 사이의 연결에 관련된 문제임을 깨닫게 해 준다. 이를 통해서 우리는 노화는 현재의 자기와 미래의 자기 사이에 생적 자원을 배분하는 자연경제적 문제를 드러내며, 이 문제에 대한 근본적인 해결책은 없다는 점을 지적할 것이다. 결론적으로, 노화는 불가피하지만 그럼에도 노화의 방식에는 다양한 가능성이 있다는 것, 그리고 이러한 가능성들의 관점에서 생명체와 인간 문명을 바라보는 과제가 노화의 철학적 문제임이 드러난다. (shrink)

Recent scandals allegedly linked to CEO compensation have brought executive compensation and perquisites to the forefront of debate about constraining executive compensation and reforming the associated corporate governance structure. We briefly describe the structure of executive compensation, and the agency theory framework that has commonly been used to conceptualize executives acting on behalf of shareholders. We detail some criticisms of executive compensation and associated ethical issues, and then discuss what previous research suggests are likely intended and unintended consequences of some (...) widely proposed executive compensation reforms. We explicitly discuss the following recommendations for reform: require greater independence of compensation committees, require executives to hold equity in the corporation, require greater disclosure of executive compensation, increase institutional investor involvement in corporate governance (including executive compensation), and require firms to expense stock options on their income statements. We provide a brief summary discussion of ethical issues related to executive compensation, and describe possible future research. (shrink)

Prior studies assert that social trust may positively influence the economic performance of countries and firms (within those countries). This paper proposes a more nuanced mechanism whereby corporate social responsibility (CSR) mediates the relationship between country-level social trust and firm-level financial performance. Anchored in neo-institutional theory, we theorize that social trust instills norms of trustworthiness and willingness to trust others guiding individual and corporate behaviors. In order to comply with such norms and gain legitimacy, firms in high-trust society are more (...) likely to commit to CSR activities that serve the interests of stakeholders. CSR activities, in turn, can positively influence financial performance by enabling firms to access stakeholders' resources and capabilities and to decrease transactions costs in the stakeholder relationships. We tested our theory by analyzing 9818 firm-year observations across 34 countries, during the 2006 to 2015 period. Our analysis shows the expected CSR mediation in the relationship between social trust and firm-level financial performance. Our findings are robust across different models addressing the concerns of endogeneity, alternative measures, and potential moderators. (shrink)

Through corporate social responsibility activities, a firm can develop the capability for managing and benefiting from stakeholder relationships. This study refers to such a capability as stakeholder influence capacity. In a host country, locally sourcing parts and/or materials can generate economic value and improve social welfare. Moreover, local sourcing provides opportunities for a foreign firm to apply and advance SIC while closely interacting with host-country stakeholders. Accordingly, we expect that a firm, having gained SIC through CSR activities in its home (...) country, will be more likely to source parts and/or materials in the host country. We also expect that the relationship between SIC and host-country sourcing is conditional upon a foreign firm’s intangible resources and liabilities of foreignness. Our empirical analysis, using Korean datasets, supports the positive relationship between CSR and local sourcing. We find that this positive relationship is more pronounced either when the firm is committed to technology development or when its home and host countries are geographically or culturally distant. (shrink)

This study examines a deep-seated anti-missionary sentiment of Korean theologians and church historians. Chai-Choon Kim and Jong-Sung Rhee were arguably most responsible for popularizing anti-missionary sentiment among Korean Christians. The main reason for the criticisms of both Kim and Rhee against the American Presbyterian Korea missionaries was the supposedly fundamentalist schisms of the Presbyterian Church of Korea in the 1950s, which both Kim and Rhee reasoned to have been originated from their Old Princeton theology. The theological rationale of both Kim (...) and Rhee was the Barthian triumph frame that the Reformed Orthodoxy including the Old Princeton theology, which had been suspected of having a fundamentalist tendency, was overcome by Karl Barth’s Neo-Orthodoxy. These theological anti-missionary criticisms facilitated some younger Korean church historians, especially both Kyung-Bae Min and Man-Yul Lee, to view Korean church history from an anti-missionary, Korean ethnic nationalist perspective. Min emphasizes some seemingly good but anecdotal works of individual Korean native Christians, hence resulting in depreciation of the works of the missionaries and their Korean coworkers. Following Min, Lee goes even further, praising what some individual Korean Christians did for socio-political (anti-establishment) purposes and ignoring what the missionaries and their Korean coworkers did cooperatively for their Korean churches. Those Korean theologians and church historians with quite a strong anti-missionary sentiment might have succeeded in arousing Korean Christians’ ethnic nationalism, but in so doing, they have quite surely deprived Korean Christians of their critically significant and rich ecclesiastical and theological elements which have been originated from the missionaries. (shrink)

This paper explores how undergraduate students understood the social relevance of their engineering course content knowledge and drew broader social and ethical implications from that knowledge. Based on a three-year qualitative study in a junior-level engineering class, we found that students had difficulty in acknowledging the social and ethical aspects of engineering as relevant topics in their coursework. Many students considered the immediate technical usability or improved efficiency of technical innovations as the noteworthy social and ethical implications of engineering. Findings (...) suggest that highly-structured engineering programs leave little room for undergraduate students to explore the ethical dimension of engineering content knowledge and interact with other students/programs on campus to expand their “technically-minded” perspective. We discussed the issues of the “culture of disengagement” :42–72, 2014) fueled by disciplinary elitism, spatial distance, and insulated curriculum prevalent in the current structure of engineering programs. We called for more conscious effort by engineering educators to offer meaningful interdisciplinary engagement opportunities and in-class conversations on ethics that support engineering students' holistic intellectual growth and well-rounded professional ethics. (shrink)

To ensure their survival in natural habitats, plants must recognize and respond to a wide variety of insect herbivores. Aphids and other Hemiptera pose a particular challenge, because they cause relatively little direct tissue damage when inserting their slender stylets intercellularly to feed from the phloem sieve elements. Plant responses to this unusual feeding strategy almost certainly include recognition of aphid salivary components and the induction of phloem‐specific defenses. Due to the excellent genetic and genomic resources that are available for (...) Arabidopsis thaliana (Arabidopsis), this plant was chosen as a model system to study the metabolic and transcriptional responses to infestation by two aphids, Myzus persicae (green peach aphid, a broad generalist) and Brevicoryne brassicae (cabbage aphid, a crucifer‐feeding specialist). Future research on Arabidopsis–aphid interactions will lead to the identification of aphid‐specific elicitors, components of the defense‐signaling pathway, and additional metabolic responses that are induced by aphid infestation. BioEssays 29:871–883, 2007. © 2007 Wiley Periodicals, Inc. (shrink)