Background Reasonable disagreement about the role awarded to gamete donors in decision-making on the use of embryos created by gamete donation for research purposes emphasises the importance of considering the implementation of participatory, adaptive, and trustworthy policies and guidelines for consent procedures. However, the perspectives of gamete donors and recipients about decision-making regarding research with EGDs are still under-researched, which precludes the development of policies and guidelines informed by evidence. This study seeks to explore the views of donors and recipients (...) about who should take part in consent processes for the use of EGDs in research. Methods From July 2017 to June 2018, 72 gamete donors and 175 recipients completed a self-report structured questionnaire at the Portuguese Public Bank of Gametes. Agreement with dual consent was defined as the belief that the use of EGDs in research should be consented by both donors and recipients. Results The majority of participants were willing to donate embryos for research. Almost half of the donors and half of the recipients considered that a dual consent procedure is desirable. This view was more frequent among employed recipients than among non-employed. Donors were less likely to believe that only recipients should be involved in giving consent for the use of EGDs in research and were more frequently favourable to the idea of exclusive donors’ consent. Conclusions Divergent views on dual consent among donors and recipients indicate the need to develop evidence-based and ethically sustainable policies and guidelines to protect well-being, autonomy and reproductive rights of both stakeholder groups. More empirical research and further theoretical normative analyses are needed to inform people-centred policy and guidelines for shared decision-making concerning the use of EGDs for research. (shrink)

Many philosophers believe that truth is grounded: True propositions depend for their truth on the world. Some philosophers believe that truth’s grounding has implications for our ontology of time. If truth is grounded, then truth supervenes on being. But if truth supervenes on being, then presentism is false since, on presentism, e.g., that there were dinosaurs fails to supervene on the whole of being plus the instantiation pattern of properties and relations. Call this the grounding argument against presentism. Many presentists (...) claim that the grounding argument fails because, despite appearances, supervenience is compatible with presentism. In this paper, I claim that the grounding argument fails because, despite appearances, truth’s grounding gives the presentist no compelling reason to adopt the sort of supervenience principle at work in the grounding argument. I begin by giving two precisifications of the grounding principle: truthmaking and supervenience. In Sect. 2, I give the grounding argument against presentism. In Sect. 3, I argue that we should distinguish between eternalist and presentist notions of grounding; once this distinction is in hand, the grounding argument is undercut. In Sect. 4, I show how the presentist’s notion of grounding leads to presentist-friendly truthmaking and supervenience principles. In Sect. 5, I address some potential objections. (shrink)

jild-i 1. Chand maqālah darbārah-ʼi maqāmāt-i [i.e. maqālāt] ʻilmī, va mujāhadāt-i farhangī, va khadamāt-i Islāmī-i ū-- -- jild-i 2. Chand maqālah az Prūfisūr ʻAbd al-Javād Falāṭūrī Iṣfahānī.

R.I.G. Hughes presents a series of eight philosophical essays on the theoretical practices of physics. The first two essays examine these practices as they appear in physicists' treatises (e.g. Newton's Principia and Opticks ) and journal articles (by Einstein, Bohm and Pines, Aharonov and Bohm). By treating these publications as texts, Hughes casts the philosopher of science in the role of critic. This premise guides the following 6 essays which deal with various concerns of philosophy of physics such as laws, (...) disunities, models and representation, computer simulation, explanation, and the discourse of physics. (shrink)

James I. The Political Works of James I. Reprinted from the Edition of 1616. With an Introduction by Charles Howard McIlwain. Cambridge: Harvard University Press, 1918. cxi, 354 pp. Reprinted 2002 by The Lawbook Exchange, Ltd.