Due to aging populations and the prolonging of working lives, the number of senior workers will increase. Therefore, this study investigates the use of SOC strategies across organizational levels as a means for senior workers to maintain workability and age successfully at work. The need to expand the perspective of the SOC model beyond the individual level, when applied to a work context, has been emphasized theoretically in the literature, nevertheless, SOC strategies have so far only been examined at the (...) individual level. This study is the first to explore SOC strategies at the organizational, leadership, and group level. We focus on senior employees and the SOC strategies they use to balance out demands and limited resources. Based on 23 semi-structured interviews with senior employees and immediate managers at two hospitals, and two dairies, we explore which specific SOC strategies are used at each level and reflect on the applicability of broadening the perspective of the SOC model when applying it to a work context. Based on the empirical findings and the discussion of the empirical exploration of SOC strategies beyond the individual level, we argue that it is advantageous to further pursue this line of inquiry and include the group, leadership, and organizational level when applying the SOC model in a work setting. (shrink)

In this study, we demonstrate how perceptions of nursing are constructed in close connection with the development of the Nordic welfare states. Drawing on Gillian Rose's framework for analysing the social and political implications of visual materials, we analysed selected visual representations of nursing published in Danish and Norwegian professional nursing journals in the period 1965 to 2016. The analyses were conducted in an iterative process in three phases. First, we reviewed all visuals spanning the entire period to obtain an (...) overview of developmental trends in the material. Second, selected visuals and associated captions were subjected to more thorough analysis. Third, we further examined and discussed the visuals in light of societal and political movements and ideologies in Danish and Norwegian healthcare policies over this period. Our analysis shows that visual representations of the nurse–patient relationship and of the patient's and the nurse's roles and responsibilities changed over this period and that the visualisations corresponded with and supported developments in the Danish and Norwegian welfare states as these first consolidated and then moved towards individualisation and the competition state. Our study demonstrates that nurses in these states are political actors implementing health policies embedded in various knowledge regimes. (shrink)

A response to Lindsay Craig's essay, The So-Called Extended Synthesis and Population Genetics.

Neurodegenerative syndromes present as proteinopathies – does ribosomal infidelity contribute to the protein toxicity that is the driving force for neuronal cell loss? Intracellular and extracellular protein aggregates overwhelm the clearance capacity of cells and tissues. Proteins aggregate when hydrophobic residues are exposed. Hydrophobic residues become exposed when proteins are misfolded. Protein misfolding can originate from translational errors at the ribosome. Indeed, the most error‐prone process in gene expression is translation at the ribosome. Recent evidence indicates that manipulating the ribosomal (...) accuracy impacts on the lifespan of model organisms and a reduced translational accuracy is accompanied by neurodegeneration. The first hit in aging‐associated neurodegenerative disease may be the well‐documented decline of cellular buffering capacity by aging. A second hit that impacts on the quality of protein synthesis could be the driving force for the observed loss of proteostasis in neurodegeneration. This hypothesis provides an explanation for the late onset of most neurodegenerative diseases. (shrink)

Ledelse i autenticitetens tidsalder – Fra undertrykkelse til udtrykkelse.

Gerd Buchdahl; XIV—The Relation Between ‘Understanding’ and ‘Reason’ in the Architectonic of Kant's Philosophy1, Proceedings of the Aristotelian Society, Volume.

Kierkegaard portrays his role as an author with the image of a prompter in “An Occasional Discourse” of 1847. A prompter in the theatre whispers not his own words, but a text by someone else already familiar to the actors on stage. This raises the question as to which text Kierkegaard is prompting. I seek to answer the question through a close reading of his imagery of authorial withdrawal in this discourse in connection with his repeated description of his writings (...) as readings of the original text of individual human existence-relationships, the old familiar text handed down from the fathers. (shrink)

Kierkegaard dismissed the quest for the historical Jesus that dominated historical‐critical biblical scholarship in the nineteenth century. Instead of historical reconstructions of the life of Jesus, he embarked on polyphonic rewritings of the story of the life of Jesus from still new perspectives. This chapter investigates how Kierkegaard's different narrations of the “life of Jesus” inscribe the New Testament texts and imitate their narrative art, particularly the role of dramatic irony, in relation to Kierkegaard's metareflections on how to communicate this (...) story in a modern age. (shrink)

This article critically examines and discusses the charge, raised by Adorno in his essay on Works of Love, that Kierkegaard’s rewriting of the Gospel story of the good Samaritan reduces neighbor love to abstract inwardness. It has been somewhat ignored in the reception of Adorno’s text that he also praises Kierkegaard as a critic of his time. I explore Adorno’s appreciation of this dimension in Works of Love and seek to develop it further by examining Kierkegaard’s sharp eye for discovering (...) how the inhumanity of the slavery in the past persists in more hidden and subtle ways in the modern world dominated by the instrumental rationality of economics. (shrink)

Automated theorem proving amounts to solving search problems in usually tremendous search spaces. A lot of research therefore focuses on search space reductions. Our approach reduces the search space which arises when using so-called connection tableau calculi for first-order automated theorem proving. It uses disjunctive constraints over first-order equations to compress certain parts of this search space. We present the basics of our constrained-connection-tableau calculi, a constraint extension of connection tableau calculi, and deal with the efficient handling of constraints during (...) the search process. The new techniques are integrated into the automated connection tableau prover Setheo. (shrink)

Automated theorem proving amounts to solving search problems in usually tremendous search spaces. A lot of research therefore focuses on search space reductions. Our approach reduces the search space which arises when using so-called connection tableau calculi for first-order automated theorem proving. It uses disjunctive constraints over first-order equations to compress certain parts of this search space. We present the basics of our constrained-connection-tableau calculi, a constraint extension of connection tableau calculi, and deal with the efficient handling of constraints during (...) the search process. The new techniques are integrated into the automated connection tableau prover Setheo. (shrink)

I. Reputed shortcomings of Descartes as philosopher of science.II ‘Knowledge’ in mathematics and in physics. The ‘ontological’ postulates of Descartes's philosophy and philosophy of physics.III. The ‘foundations of dynamics’: ‘Newton's First Law of Motion’ and its status.IV. Descartes's conception of ‘hypothesis’: the competing claims of the ideal of the a priori in physics and the conception of retroductive inference. V. Descartes's notion of ‘analysis’. The distinction between ‘procedure’ and ‘inference’. The notion of ‘induction’ and ‘understanding through models’: ‘Snell's Law of (...) Refraction’. (shrink)

The Leuphana Semester at Leuphana University Lüneburg, together with the module “Science bears responsibility” demonstrate how innovative methods of teaching and learning can be combined with the topic of sustainable development and how new forms of university teaching can be introduced. With regard to module content, it has become apparent that, due to the complexity of the field of sustainability, a single discipline alone is unable to provide analyses and solutions. If teaching in higher education is to adequately deal with (...) this complexity, then it is necessary to develop inter- and transdisciplinary approaches that go beyond a purely specialist orientation. (shrink)

Simple Heuristics That Make Us Smart invites readers to embark on a new journey into a land of rationality that differs from the familiar territory of cognitive science and economics. Traditional views of rationality tend to see decision makers as possessing superhuman powers of reason, limitless knowledge, and all of eternity in which to ponder choices. To understand decisions in the real world, we need a different, more psychologically plausible notion of rationality, and this book provides it. It is about (...) fast and frugal heuristics--simple rules for making decisions when time is pressing and deep thought an unaffordable luxury. These heuristics can enable both living organisms and artificial systems to make smart choices, classifications, and predictions by employing bounded rationality. But when and how can such fast and frugal heuristics work? Can judgments based simply on one good reason be as accurate as those based on many reasons? Could less knowledge even lead to systematically better predictions than more knowledge? Simple Heuristics explores these questions, developing computational models of heuristics and testing them through experiments and analyses. It shows how fast and frugal heuristics can produce adaptive decisions in situations as varied as choosing a mate, dividing resources among offspring, predicting high school drop out rates, and playing the stock market. As an interdisciplinary work that is both useful and engaging, this book will appeal to a wide audience. It is ideal for researchers in cognitive psychology, evolutionary psychology, and cognitive science, as well as in economics and artificial intelligence. It will also inspire anyone interested in simply making good decisions. (shrink)

In this volume the author tackles this problem in a rigorous analysis which begins with the general dynamics of living systems and leads the reader step-by-step ...

Within the highly organized nuclear structure, specific nuclear domains (ND10) are defined by accumulations of proteins that can be interferon-upregulated, implicating ND10 as sites of a nuclear defense mechanism.Compatible with such a mechanism is the deposition of herpesvirus, adenovirus, and papovavirus genomes at the periphery of ND10. However, these DNA viruses begin their transcription at ND10 and consequently initiate replication at these sites, suggesting that viruses have evolved ways to circumvent this potential cellular defense and exploit it. Other ND10-associated proteins (...) belong to ubiquitin-related pathways. These findings, together with the accumulation of various overexpressed cellular and viral proteins, suggest that ND10 function as nuclear dumps or as nuclear depots. Consistent with the recruitment or deposition of various proteins and viral genomes adjacent to ND10, ND10 themselves may only be protein accumulations at specific but as yet undefined nuclear deposition sites. The concept of specific nuclear deposition sites may explain the juxtaposition of various nuclear bodies and allows testable predictions about a potential supramolecular regulatory mechanism whereby proteins are selectively segregated or released by global changes induced in nuclear functions such as viral infections, stress, or hormonal induction. BioEssays 20:660–667, 1998.© 1998 John Wiley & Sons Inc. (shrink)

Within the highly organized nuclear structure, specific nuclear domains (ND10) are defined by accumulations of proteins that can be interferon-upregulated, implicating ND10 as sites of a nuclear defense mechanism.Compatible with such a mechanism is the deposition of herpesvirus, adenovirus, and papovavirus genomes at the periphery of ND10. However, these DNA viruses begin their transcription at ND10 and consequently initiate replication at these sites, suggesting that viruses have evolved ways to circumvent this potential cellular defense and exploit it. Other ND10-associated proteins (...) belong to ubiquitin-related pathways. These findings, together with the accumulation of various overexpressed cellular and viral proteins, suggest that ND10 function as nuclear dumps or as nuclear depots. Consistent with the recruitment or deposition of various proteins and viral genomes adjacent to ND10, ND10 themselves may only be protein accumulations at specific but as yet undefined nuclear deposition sites. The concept of specific nuclear deposition sites may explain the juxtaposition of various nuclear bodies and allows testable predictions about a potential supramolecular regulatory mechanism whereby proteins are selectively segregated or released by global changes induced in nuclear functions such as viral infections, stress, or hormonal induction. BioEssays 20:660–667, 1998.© 1998 John Wiley & Sons Inc. (shrink)

In the debate regarding the different possibilities for gene therapy, it is presupposed that the manipulations are limited to the nuclear genome (nDNA). Given recent advances in genetics, mitochondrial genome (mtDNA) and diseases must be considered as well. In this paper, we propose a three dimensional framework for the ethical debate of gene therapy where we add the genomic type (nDNA vs. mtDNA) as a third dimension to be considered beside the paradigmatic dimensions of target cell (somatic vs. germ-line) and (...) purpose (therapeutic vs. enhancement). Somatic gene therapy can be viewed today as generally accepted, and we review t he contemporary arguments surrounding it on the basis of bioethical-pragmatic, socio-political and deontological classifications. Many of the supposed ethical questions of somatic gene therapy today are not new; they are well-known issues of research ethics. We also critically summarize the different international perspectives and the German ethical discussion regarding manipulations of germ-line cells. (shrink)

Evidence-based recommendations for lifestyles to promote healthy cognitive aging root in reductionistic studies of mostly physical measurable factors with large effect sizes. In contrast, most people consider factors like autonomy, purpose, social participation and engagement, etc. as central to a high quality of life in old age. Evidence for a direct causal impact of these factors on healthy cognitive aging is still limited, albeit not absent. Ultimately, however, individual lifestyle is a complex composite of variables relating to both body and (...) mind as well as to receiving input and generating output. The physical interventions are tied to the more subjective and mind-related aspects of lifestyle and wellbeing in the idea of the “embodied mind,” which states that the mind is shaped by and requires the body. The causality is reciprocal and the process is dynamic, critically requiring movement: the “embodied mind” is a “embodied mind in motion.” Hiking, playing musical instruments, dancing and yoga are examples of body–mind activities that assign depth, purpose, meaning, social embedding, etc. to long-term beneficial physical “activities” and increase quality of life not only as delayed gratification. The present motivational power of embodied activities allows benefiting from the side-effects of late-life resilience. The concept offers an access point for unraveling the mechanistic complexity of lifestyle-based prevention, including their neurobiological foundations. (shrink)

This volume collects Gigerenzer's recent articles on the psychology of rationality. This volume should appeal, like the earlier volumes, to a broad mixture of cognitive psychologists, philosophers, economists, and others who study decision making.

The Empire of Chance tells how quantitative ideas of chance transformed the natural and social sciences, as well as daily life over the last three centuries. A continuous narrative connects the earliest application of probability and statistics in gambling and insurance to the most recent forays into law, medicine, polling and baseball. Separate chapters explore the theoretical and methodological impact in biology, physics and psychology. Themes recur - determinism, inference, causality, free will, evidence, the shifting meaning of probability - but (...) in dramatically different disciplinary and historical contexts. In contrast to the literature on the mathematical development of probability and statistics, this book centres on how these technical innovations remade our conceptions of nature, mind and society. Written by an interdisciplinary team of historians and philosophers, this readable, lucid account keeps technical material to an absolute minimum. It is aimed not only at specialists in the history and philosophy of science, but also at the general reader and scholars in other disciplines. (shrink)

The well-known proposal to consider the Lüders-von Neumann measurement as a non-classical extension of probability conditionalization is further developed. The major results include some new concepts like the different grades of compatibility, the objective conditional probabilities which are independent of the underlying state and stem from a certain purely algebraic relation between the events, and an axiomatic approach to quantum mechanics. The main axioms are certain postulates concerning the conditional probabilities and own intrinsic probabilistic interpretations from the very beginning. A (...) Jordan product is derived for the observables, and the consideration of composite systems leads to operator algebras on the Hilbert space over the complex numbers, which is the standard model of quantum mechanics. The paper gives an expository overview of the results presented in a series of recent papers by the author. For the first time, the complete approach is presented as a whole in a single paper. Moreover, since the mathematical proofs are already available in the original papers, the present paper can dispense with the mathematical details and maximum generality, thus addressing a wider audience of physicists, philosophers or quantum computer scientists. (shrink)

Together, these collected papers develop the idea that human thinking - from scientific creativity to simply understanding what a positive HIV test means - "happens" partly outside the mind.".