地球環境問題など、文明社会がもたらしたさまざまな負の作用がクローズアップされているいま、必要なのは量の時代から質の時代への移行である。「人間」「科学」「技術」がどのように相互作用してきたかをふりかえり 、人間、自然、地球が豊かになるための道をさぐる。.

The aim of this paper is to examine the relationship between education and technological rationality from the perspective of the philosophy of education, and to show that while education is deeply related to technique, skills, or technology, it can never be reduced to technical knowledge, and that there are things in education that overflow technical knowledge. I will here ask why there is something in education that overflows technical knowledge — I will define it as knowledge of pathos — and (...) why it is necessary to redefine the meaning of education in terms of knowledge of pathos. In order to address this issue, I will first examine the relationship between technology and transcendence in the world of education in Kei Hachiya’s Education and Transcendence. Second, I will show that recent outstanding theoretical achievements of Japanese philosophers of education — Satoji Yano’s Education from the Perspectives of Gift and Exchange, Yasuo Imai’s Medial Perspective on Education, and Tsunemi Tanaka’s Clinical Theory of Human Becoming — are all located within the problematic area of ‘technology-pathos-education’. Finally, I would like to propose a ‘philosophy of education built on fragile parts’, with a view to redefining education through the knowledge of pathos, paying attention to the experience of pathei mathos and the opportunity of weakness in the philosophy of education. (shrink)

This is a brief historical view, based on my personal experience, of the phenomenological study of the assembly of actin in Japan. The morphogenesis and dynamics of protein filaments and cytoskeleton now represent one of the central problems in cell biology. The approach to this problem at the molecular level was first undertaken on actin from muscle.

For each intermediate propositional logicJ, J * denotes the least predicate extension ofJ. By the method of canonical models, the strongly Kripke completeness ofJ *+D(=x(p(x)q)xp(x)q) is shown in some cases including:1. J is tabular, 2. J is a subframe logic. A variant of Zakharyashchev's canonical formulas for intermediate logics is introduced to prove the second case.

The logic CD is an intermediate logic which exactly corresponds to the Kripke models with constant domains. It is known that the logic CD has a Gentzen-type formulation called LD and rules are replaced by the corresponding intuitionistic rules) and that the cut-elimination theorem does not hold for LD. In this paper we present a modification of LD and prove the cut-elimination theorem for it. Moreover we prove a “weak” version of cut-elimination theorem for LD, saying that all “cuts” except (...) some special forms can be eliminated from a proof in LD. From these cut-elimination theorems we obtain some corollaries on syntactical properties of CD: fragments collapsing into intuitionistic logic. Harrop disjunction and existence properties, and a fact on the number of logical symbols in the axiom of CD. (shrink)

Fanconi anaemia (FA) comprises a group of autosomal recessive disorders resulting from mutations in one of eight genes (FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF and FANCG). Although caused by relatively simple mutations, the disease shows a complex phenotype, with a variety of features including developmental abnormalities and ultimately severe anaemia and/or leukemia leading to death in the mid teens. Since 1992 all but two of the genes have been identified, and molecular analysis of their products has revealed a complex (...) mode of action. Many of the proteins form a nuclear multisubunit complex that appears to be involved in the repair of double‐strand DNA breaks. Additionally, at least one of the proteins, FANCC, influences apoptotic pathways in response to oxidative damage. Further analysis of the FANC proteins will provide vital information on normal cell responses to damage and allow therapeutic strategies to be developed that will hopefully supplant bone marrow transplantation. BioEssays 24:439–448, 2002. © 2002 Wiley Periodicals, Inc. (shrink)

One of the profound changes in cellular morphology during mitosis is a massive alteration in the organization of microfilament cytoskeleton. It has been recently discovered that nonmuscle caldesmon, an actin and calmodulin binding microfilament‐associated protein of relative molecular mass Mr = 83000, is dissociated from microfilaments during mitosis, apparently as a consequence of mitosis‐specific phosphorylation. cdc2 kinase, which is a catalytic subunit of MPF (maturation or mitosis promoting factor), is found to be responsible for the mitosis‐specific phosphorylation of caldesmon. Because (...) caldesmon is implicated in the regulation of actin myosin interactions and/or microfilament organization, these results suggest that cdc2 kinase directly affects microfilament re‐organization during mitosis. (shrink)

We generalize the incompleteness proof of the modal predicate logic Q-S4+ p p + BF described in Hughes-Cresswell [6]. As a corollary, we show that, for every subframe logic Lcontaining S4, Kripke completeness of Q-L+ BF implies the finite embedding property of L.

In spite of the existence of many examples of incomplete logics, it is an important problem to find intermediate predicate logics complete with respect to Kripke frame (or Kripke sheaf) semantics because they are closed under substitution. But, most of known completeness proofs of finitely axiomatizable logics are difficult to apply to other logics since they are highly dependent on the specific properties of given logics. So, it is preferable to find a general methods of completeness proof. We give some (...) results on this problem using canonical formulas of "propositional" logics 8,2ESS. (shrink)

How can we effectively promote the public’s prevention of coronavirus disease 2019 infection? Jordan et al. found with United States samples that emphasizing either self-interest or collective-interest of prevention behaviors could promote the public’s prevention intention. Moreover, prosocially framed messaging was more effective in motivating prevention intention than self-interested messaging. A dual consideration of both cultural psychology and the literature on personalized matching suggests the findings of Jordan et al. are counterintuitive, because persuasion is most effective when the frame of (...) the message delivered and the recipient of the message are culturally congruent. In order to better understand the potential influence of culture, the current research aimed to replicate and extend Jordan et al. findings in the Japanese context. Specifically, we examined the question whether the relative effectiveness of the prosocial appeal is culturally universal and robust, which types of ‘others’ especially promote prevention intention, and which psychological mechanisms can explain the impact of messaging on prevention intention. In Study 1, we confirmed that self-interested framed, prosocially framed, and the combination of both types of messaging were equally effective in motivating prevention intention. In Study 2, we found that family-framed messaging also had a promoting effect similar to that from self-interested and prosocial appeals. However, the relative advantage of prosocial appeals was not observed. Further, a psychological propensity relevant to sensitivity to social rejection did not moderate the impact of messaging on prevention intention in both studies. These results suggest that since engaging in the infection control itself was regarded as critical by citizens after public awareness of COVID-19 prevention has been sufficiently heightened, for whom we should act might not have mattered. Further, concerns for social rejection might have had less impact on the prevention intentions under these circumstances. These results suggest that the relative advantage of a prosocial appeal might not be either culturally universal or prominent in a collectivistic culture. Instead, they suggest that the advantages of such an appeal depends on the more dynamic influence of COVID-19 infection. (shrink)