When the first edition of Pediatric Psychopharmacology published in 2002, it filled a void in child and adolescent psychiatry and quickly establishing itself as the definitive text-reference in pediatric psychopharmacology. While numerous short, clinically focused paperbacks have been published since then, no competitors with the scholarly breadth, depth, and luster of this volume have emerged. In the second edition, Christopher Kratochvil, MD, a highly respected expert in pediatric psychopharmacology, joins the outstanding editorial team led by Dr. Martin and Dr. Scahill. (...) In the new edition, the editors streamline the flow of information to reflect the growth in scientific data since the first edition appeared. The overall structure of the book remains the same, with major sections on underlying biology; somatic interventions; assessment and treatment; and special considerations. (shrink)

Although theoretical underpinnings of stakeholder dialog (SD) have been extensively discussed in the extant literature, there is a lack of empirical studies presenting evidence on the SD initiatives undertaken by firms. In this article, we provide information about 294 SD initiatives collected through a content analysis of the sustainability reports published by large firms in Germany, Italy, and the U. S. In addition to a country-based description of the different forms, stakeholder categories, and topics of the SD initiatives, we explore (...) the relationship between SD and characteristics of national business systems. Overall, we find firms undertake few SD initiatives, using low-involvement forms of dialog, and focusing on one category of stakeholders per initiative. Results suggest that the explicit approach to corporate social responsibility (CSR) favors the quantity of SD initiatives, but neglects the importance of the level of involvement and diversity of stakeholders participating at the dialog. Finally, we find public policies on CSR have a substantial influence on SD in national business systems with an implicit approach to CSR. Public policies based on a shared discussion involving multiple social actors encourage SD initiatives that use different forms of dialog and are characterized by high level of involvement. Our findings offer contributions to the ongoing debate about the effectiveness of SD and its relationship with CSR. (shrink)

Understood as a psychological phenomenon, there has been very little discussion of cryptomnesia in the philosophical literature. Cryptomnesia presents us with a strange phenomenon in which we take ourselves to be imagining, but the thought or idea that we entertain actually involves remembered content. In this paper, we argue for a three-factor account of cryptomnesia, according to which it is a mnemonic phenomenon that involves imagination. We provide an account of both the ‘mnemonic’ and ‘imaginative’ aspects of cryptomnesia in terms (...) of the attitude, the content, and the metacognitive processes involved in those states. In addition, we show how our three-factor account is better suited to account for cryptomnesia than competing philosophical theories of episodic memory. We conclude by discussing how the three-factor account sheds light on a range of other mnemonic and imaginative phenomena. (shrink)

Osvald Demuth studied constructive analysis from the viewpoint of the Russian school of constructive mathematics. In the course of his work he introduced various notions of effective null set which, when phrased in classical language, yield a number of major algorithmic randomness notions. In addition, he proved several results connecting constructive analysis and randomness that were rediscovered only much later.In this paper, we trace the path that took Demuth from his constructivist roots to his deep and innovative work on the (...) interactions between constructive analysis, algorithmic randomness, and computability theory. We will focus specifically on Demuth’s work on the differentiability of Markov computable functions and his study of constructive versions of the Denjoy alternative, Demuth’s independent discovery of the main notions of algorithmic randomness, as well as the development of Demuth randomness, and the interactions of truth-table reducibility, algorithmic randomness, and semigenericity in Demuth’s work. (shrink)

The 12 chapters cover 6 questions: I. What is the relationship between memory and imagination? II. Do memory traces have content? III. What is the nature of mnemonic confabulation? IV. What is the function of episodic memory? V. Do non-human animals have episodic memory? VI. Does episodic memory give us knowledge of the past?

Natural selection is commonly seen not just as an explanation for adaptive evolution, but as the inevitable consequence of “heritable variation in fitness among individuals”. Although it remains embedded in biological concepts, such a formalisation makes it tempting to explore whether this precondition may be met not only in life as we know it, but also in other physical systems. This would imply that these systems are subject to natural selection and may perhaps be investigated in a biological framework, where (...) properties are typically examined in light of their putative functions. Here we relate the major questions that were debated during a three-day workshop devoted to discussing whether natural selection may take place in non-living physical systems. We start this report with a brief overview of research fields dealing with “life-like” or “proto-biotic” systems, where mimicking evolution by natural selection in test tubes stands as a major objective. We contend the challenge may be as much conceptual as technical. Taking the problem from a physical angle, we then discuss the framework of dissipative structures. Although life is viewed in this context as a particular case within a larger ensemble of physical phenomena, this approach does not provide general principles from which natural selection can be derived. Turning back to evolutionary biology, we ask to what extent the most general formulations of the necessary conditions or signatures of natural selection may be applicable beyond biology. In our view, such a cross-disciplinary jump is impeded by reliance on individuality as a central yet implicit and loosely defined concept. Overall, these discussions thus lead us to conjecture that understanding, in physico-chemical terms, how individuality emerges and how it can be recognised, will be essential in the search for instances of evolution by natural selection outside of living systems. (shrink)

The emergence of new platforms for public communication, public deliberation, and public action presents new possibilities for forming, organizing, and mobilizing public bodies, which invite philosophical reflection concerning the standards we currently look to for coordinating public movements and for evaluating their effects. Developing a broad understanding of public philosophy, this article begins with the view of philosophy and intellectual freedom articulated in Kant's publicly oriented writings. We then focus on the power of philosophical discourse to form and further articulate (...) public bodies. Drawing on Dewey's work, we discuss the role of philosophical discourse in the articulation of publics into self-regulated, sovereign entities. We conclude with an account of how publishing itself might come to play an important role in the practice of public philosophy in a digital age. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

Pierre Maquet1,2,6, Steven Laureys1,2, Philippe Peigneux1,2,3, Sonia Fuchs1, Christophe Petiau1, Christophe Phillips1,6, Joel Aerts1, Guy Del Fiore1, Christian Degueldre1, Thierry Meulemans3, André Luxen1, Georges Franck1,2, Martial Van Der Linden3, Carlyle Smith4 and Axel Cleeremans5.

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

The Rift Valley fever (RVF), which first appeared in Kenya in 1912, is an anthropozoonosis widespread in tropical areas. In Senegal, it is particularly felt in the Ferlo area where a strong presence of ponds shared by humans, cattle and vectors is noted. As part of the studies carried out on the environmental factors which favour its start and propagation, the focus of this paper is put on the decision making process to evaluate the impacts, the interactions and to make (...) RVF monitoring easier. The present paper proposes a model based on data mining techniques and dedicated to trade experts. This model integrates all the involved data and the results of the analyses made on the characteristics of the surrounding ponds. This approach presents some advantage in revealing the relationship between environmental factors and RVF transmission vectors for space–time epidemiology monitoring purpose. (shrink)

On savait que c’était l’entité la plus complexe de l’univers connu. Mais le feu d’artifice de découvertes récentes dépasse l’entendement et fait exploser tous les schémas. Votre cerveau est (beaucoup) plus fabuleux que vous le croyez. Il est : totalement élastique, même âgé, handicapé, voire amputé de plusieurs lobes, le système nerveux central peut se reconstituer et repartir à l’assaut des connaissances et de l’action sur le monde ; totalement social, un cerveau n’existe jamais seul, mais toujours en résonance avec (...) d’autres. Mieux : nous sommes neuronalement constitués pour entrer en empathie avec autrui et aller à son secours. Ce livre aborde ces questions passionnantes avec cinq spécialistes. (shrink)

John Jewel, regarded as the principal apologist and theologian for the Elizabethan Church, was also esteemed as one of England’s most important authority on the subject of usury, and therefore was cited frequently by opponents of usury towards the end of the sixteenth century and throughout the seventeenth century. One of the most sustained interpretations of Jewel as a theologian on the subject of usury was by Christoph Jelinger, who observed that the late bishop of Sarum employed the same theological (...) method in opposing usury as he did in defending the doctrines and practices of the Church of England against its Catholic opponents, that is, by appealing to the Scriptures, the Church Fathers, Church Councils, and the example of the primitive church. This article seeks to confirm the opinion of Jelinger, and in doing so show that Jewel’s opposition to usury stemmed primarily from the conviction that it was both a vice and heresy that eroded the unifying attribute of Christian society which was love. (shrink)

Será entrando en el siglo XXI, cuando la configuración tecnológica digital, con sus redes virtuales, tecnocientíficas y sus flujos de información, solidifican el cibermundo, el cual, como sistema, está constituido por fibras de poder, control virtual y sus componentes económico, educativo, político y cultural. Con ellos tenemos ciberpolítica, cibereconomía y cibercultura en esas sociedades de redes sociales, las cuales han producido acontecimientos distintos de otros tiempos históricos. Vivimos unos tiempos cibernéticos muy diferentes a los que describieron filósofos y sociólogos como (...) Ortega y Gasset, Christopher Lasch, Michael Young o Daniel Bell. Los nuevos discursos estudian los acontecimientos sociales, políticos, educativos y culturares que se encuentran interactuando en el cibermundo, bajo condiciones de profundas desigualdades sociales, que bien trabaja el economista Piketty, por ejemplo. Como propuesta teórica, asumimos la teoría del sujeto cibernético que implica una dimensión justa de la meritocracia entre redes cibersociales, que implica las comunidades inteligentes virtuales de dimensiones ética y de resistencia cívica. (shrink)

This paper continues a dialogue that began with an article by Jeffrey Koperski entitled “Two Bad Ways to Attack Intelligent Design and Two Good Ones,” published in the June 2008 issue of Zygon: Journal of Religion and Science. In a response article, Christopher Pynes argues that ad hominem arguments are sometimes legitimate, especially when critiquing Intelligent Design (2012). We show that Pynes’s examples only apply to matters of testimony, not the kinds of arguments found in the best defenses of ID.

The prehistorian André Leroi-Gourhan envisages technological behaviour along a continuum of manual activity extending to artistic production. His work on Palaeolithic cave art, which dominates the...

The work of French ethnologist and prehistorian André Leroi-Gourhan represents an important episode in twentieth-century intellectual history. This essay follows the development of Leroi-...

El creciente interés que han suscitado los fenómenos psiquiátricos en el ámbito académico ha favorecido el desarrollo de análisis interdisciplinarios que combinan la filosofía con campos como el de la medicina, las neurociencias y las ciencias cognitivas. Un ejemplo de esto es el trabajo de John Campbell quien ha intentado analizar el fenómeno de la inserción de pensamiento y la constitución de la agencia del pensamiento a la luz del modelo de la copia eferente desarrollado por Christopher Frith y otros (...) neurofisiólogos. Inicialmente, dicho modelo fue pensando para dar cuenta de la agencia del movimiento voluntario, por lo que su aplicación en el ámbito de los fenómenos mentales es un desafío. En este texto se busca hacer una crítica del modelo planteado por Campbell, a partir de algunos de los conceptos centrales en la fenomenología de Gallagher y Zahavi y de la psiquiatría de corte fenomenológico. (shrink)

Giovanni Arrighi’s last book is compared with Andre Gunder Frank’s Re-Orient. The implications of Arrighi’s study of the East/West-comparison for comprehending world-historical evolution and the political issues of the current conjuncture are considered.

Johann Christoph Gottsched gehört unbestritten zu den zentralen Figuren der deutschen Frühaufklärung. Wie wohl kein anderer vor und nach ihm hat er die Entwicklung der deutschsprachigen Sprach-, Rede-, Dicht- und Bühnenkunst geprägt, geleitet von der festen Absicht, diesen Künsten wo möglich eine wissenschaftliche Begründung, eine überschaubare kritische Historie sowie eine klare und elegante Darstellung zu verleihen. Über diese Bemühungen hinaus, hat sich insbesondere die neuere Forschung weiteren Facetten seines riesigen Werkes zugewendet. So erscheint Gottsched als Vorbild zahlreicher Zeitschriftenprojekte, als wichtiger (...) Popularisator der Leibnizschen und Wolffschen Philosophie, als zentraler Reformer der zeitgenössischen Homiletik, als Drehscheibe bei der Vermittlung europäischer Dichtung und Gelehrsamkeit. Die Beiträge des vorliegenden Bandes tragen der gesamten Breite der Gottsched-Forschung Rechnung, prüfen alte Erkenntnisse und stellen neue Einschätzungen zur Diskussion. Darüber wird die Aufmerksamkeit auch auf weniger bekannte Aspekte des Gottschedschen Oeuvres gelenkt, so etwa auf Beiträge zu den Naturwissenschaften und der Staatslehre, auf die akademische Lehrtätigkeit und auf das zunehmende Interesse an anthropologischen und ästhetischen Fragen. MIT BEITRÄGEN VON: Erich Achermann, Thomas Althaus, Detlef Döring, Frank Grunert, Gerda Hassler, Peter Hesselmann, Hanspeter Marti, Christian Meierhofer, Dagmar Mirbach, Merio Scattola, Oliver Scholz, Tomas Sommadossi, Holger Steinmann, Gideon Stiening, Andres Strassberger, Dietmar Till, Klaus Weimar und Jan-Henrik Witthaus. (shrink)

Der Pilot und Priester, Assumptionist und Byzantinist Christopher Walter hat einen neuen unschätzbaren Beitrag zur byzantinischen Geschichte geliefert. Als Schüler von André Grabar und Kollege von Vitalien Laurent verwaltet er die reiche Wissenschaftstradition der Assumptionisten und Bollandisten. Sein grosses Wissen über Theologie, Kirchengeschichte, Patristik und Kunstwissenschaft vermittelt er in einer angenehmen fliessenden Sprache. In dieser Arbeit webt er einen kunstfertigen Gobelin und verbindet die christliche Frühgeschichte mit dem vom antiken Heroenkult übertragenen Märtyrerkult in einem tiefgreifenden Versuch, die Historizität der Kriegerheiligen (...) zu fixieren. Er bringt den kultischen Aspekt der Armee in einer Darstellung zum Leben, die sich oft zu einem spannenden Detektivroman entwickelt. Endlich können wir den beliebtesten Kriegerheiligen in einen festeren Griff bekommen, den Archistrategos, den Erzengel Michael, mit den himmlischen Heerscharen zu seiner Verfügung, zur Verteidigung der ecclesia militans und des irdischen Imperiums neben anderen Kriegerheiligen, die die Standarten der Tagmaeinheiten schmückten. (shrink)

Current work in language models (LMs) helps us speed up or even skip thinking by accelerating and automating cognitive work. But can LMs help us with critical thinking -- thinking in deeper, more reflective ways which challenge assumptions, clarify ideas, and engineer new concepts? We treat philosophy as a case study in critical thinking, and interview 21 professional philosophers about how they engage in critical thinking and on their experiences with LMs. We find that philosophers do not find LMs to (...) be useful because they lack a sense of selfhood (memory, beliefs, consistency) and initiative (curiosity, proactivity). We propose the selfhood-initiative model for critical thinking tools to characterize this gap. Using the model, we formulate three roles LMs could play as critical thinking tools: the Interlocutor, the Monitor, and the Respondent. We hope that our work inspires LM researchers to further develop LMs as critical thinking tools and philosophers and other 'critical thinkers' to imagine intellectually substantive uses of LMs. (shrink)

This reconsideration of Hume’s classic essay “Of Miracles” via the lens of American pragmatist ways of thinking about history and power shifts our attention from Hume’s epistemic concerns about the legitimacy of witnesses and testimony to his distaste for sacred history, his critical stance regarding the social force of revelation, and his disdain for religious authority. To view Hume’s essay both as an articulation of a critical philosophy of history and as an exercise in moral dynamism (social power or, authority, (...) is a result of epistemic transactions), is to intervene in both Hume studies and Contemporary Pragmatism. (shrink)

This paper argues that we should replace the common classification of theories of welfare into the categories of hedonism, desire theories, and objective list theories. The tripartite classification is objectionable because it is unduly narrow and it is confusing: it excludes theories of welfare that are worthy of discussion, and it obscures important distinctions. In its place, the paper proposes two independent classifications corresponding to a distinction emphasised by Roger Crisp: a four-category classification of enumerative theories (about which items constitute (...) welfare), and a four-category classification of explanatory theories (about why these items constitute welfare). (shrink)

This chapter surveys hybrid theories of well-being. It also discusses some criticisms, and suggests some new directions that philosophical discussion of hybrid theories might take.

Are we witnessing progress or regress in the recent increasing popularity and electoral success of populist politicians and parties in consolidated democratic nations? ... Is the innovative use of popular referendum in Great Britain to settle fundamental constitutional questions a progressive or regressive innovation? ... Similarly, is the increasing use of constituent assemblies to change constitutions across the world evidence of progress in democratic constitutionalism, or, a worryingly regressive change back toward unmediated popular majoritarianism? ... This paper reflects on some (...) of the perils and promise of framing such questions with the conceptual couplet of progress and regress. It considers four compelling critiques of the use of ‘progress’ and its cognates in sociopolitical theory, as well as arguing that such concepts are nevertheless ineliminable for our normative theories. The paper concludes by suggesting that we can avoid the most serious problems by employing only conceptions of political progress and regress that are piecemeal, pragmatic, and processual. (shrink)

Group-based reasons are reasons to play one’s part in some pattern of action that the members of some group could perform, because of the good features of the pattern. This paper discusses three broad conceptions of such reasons. According to the agency-first conception, there are no group-based reasons in cases where the relevant group is not or would not be itself an agent. According to the behaviour-first conception, what matters is that the other members of the group would play their (...) parts in the relevant pattern, not whether they would have the cooperative intentional states constitutive of group agency in doing so. This paper argues against these conceptions and in favour of the powers-first conception, according to which what matters is that the members of the group have practically relevant powers. (shrink)

Under the lig ht of Being and Nothingness’s the o re t ical body – Sartre’s master piece –, it is intended to discuss the essential source of human reality as “n i h i l a t i o n” and ontological lack, as well as manifestations and cons e q u e nces from this primordial human passion to be transformed to coagulated transcendence, to be transformed in Being In-itself-For-itself: to be consciousness and, at the same t i (...) me, to be a complete and finished Being, with infinite de nsity and witho u t fissures. (shrink)

Difficult Atheism shows how contemporary French philosophy is rethinking the legacy of the death of God in ways that take the debate beyond the narrow confines of atheism into the much broader domain of post-theological thinking. Christopher Watkin argues that Alain Badiou, Jean-Luc Nancy and Quentin Meillassoux each elaborate a distinctive approach to the post-theological, but that each approach still struggles to do justice to the death of God.

An examination of David Hume's philosophy of religion that situates his conception "true religion" within the context of his overall science of human nature, his rejection of popular religion, and his Ciceronian influence"--Provided by publisher.