Transmissible cancers are elusive and understudied parasitic life forms caused by malignant clonal cells (nine lineages are known so far). They emerge by completing sequential steps that include breaking cell cooperation, evade anti‐cancer defences and shedding cells to infect new hosts. Transmissible cancers impair host fitness, and their importance as selective force is likely largely underestimated. It is, therefore, crucial to determine how common they might be in the wild. Here, we draw a parallel between the steps required for a (...) transmissible cancer to emerge and the steps required for an intelligent civilisation to emerge in the Milky Way using a modified Drake equation. Using numerical analyses, we estimate the potential number of extant marine and bivalve species in which transmissible cancers might exist. Our results suggest that transmissible cancers are more common than expected, and that new lineages can be found by screening a large number of species. (shrink)

Insects use path integration (PI) to maintain a home vector, but can also store and recall vector-memories that take them from home to a food location, and even allow them to take novel shortcuts between food locations. The neural circuit of the Central Complex (a brain area that receives compass and optic flow information) forms a plausible substrate for these behaviours. A recent model, grounded in neurophysiological and neuroanatomical data, can account for PI during outbound exploratory routes and the control (...) of steering to return home. Here, we show that minor, hypothetical but neurally plausible, extensions of this model can additionally explain how insects could store and recall PI vectors to follow food-ward paths, take shortcuts, search at the feeder and re-calibrate their vector-memories with experience. In addition, a simple assumption about how one of multiple vector-memories might be chosen at any point in time can produce the development and maintenance of efficient routes between multiple locations, as observed in bees. The central complex circuitry is therefore well-suited to allow for a rich vector-based navigational repertoire. (shrink)

Biological evolution provides a creative fount of complex and subtle adaptations, often surprising the scientists who discover them. However, because evolution is an algorithmic process that transcends the substrate in which it occurs, evolution’s creativity is not limited to nature. Indeed, many researchers in the field of digital evolution have observed their evolving algorithms and organisms subverting their intentions, exposing unrecognized bugs in their code, producing unexpected adaptations, or exhibiting outcomes uncannily convergent with ones in nature. Such stories routinely reveal (...) creativity by evolution in these digital worlds, but they rarely fit into the standard scientific narrative. Instead they are often treated as mere obstacles to be overcome, rather than results that warrant study in their own right. The stories themselves are traded among researchers through oral tradition, but that mode of information transmission is inefficient and prone to error and outright loss. Moreover, the fact that these stories tend to be shared only among practitioners means that many natural scientists do not realize how interesting and lifelike digital organisms are and how natural their evolution can be. To our knowledge, no collection of such anecdotes has been published before. This paper is the crowd-sourced product of researchers in the fields of artificial life and evolutionary computation who have provided first-hand accounts of such cases. It thus serves as a written, fact-checked collection of scientifically important and even entertaining stories. In doing so we also present here substantial evidence that the existence and importance of evolutionary surprises extends beyond the natural world, and may indeed be a universal property of all complex evolving systems. (shrink)

La reception du christianisme byzantin par l'Eglise catholique presente une sorte d'anomalie. Invoquant l'autorite de Thomas d'Aquin, les theologiens occidentaux rejettent generalement l'idee d'une distinction reelle entre l'essence et les energies divines, tout comme la notion de grace increee, laquelle joue un role essentiel dans la vision de Gregoire Palamas (XIVe siecle). D'un autre cote, ces memes theologiens ont ete nombreux a redecouvrir, durant la periode recente, la pensee de Maxime le Confesseur (VIIe siecle), voyant en celui-ci un genial (...) precurseur de Thomas d'Aquin. Or que resterait-il de la doctrine de Gregoire Palamas sans le patronage de Maxime le Confesseur? Comment meconnaitre l'un et reconnaitre l'autre au nom du meme Thomas d'Aquin? Ce qui vient ici au jour a travers l'etude des contextes et des enjeux doctrinaux, c'est la coexistence, jusqu'alors insoupconnee, de deux representations distinctes du rapport entre le cree et l'incree. L'Occident latin et l'Orient byzantin n'en finissent pas de comprendre differemment cette foi qui leur est pourtant indiscutablement commune. (shrink)

The great richness of the work of Louis Bouyer is well known. In his first publications, Bouyer initiates a return to the sources of the liturgy, the Word and the Fathers. Very characteristically of this movement is Le mystère pascal (1945), which rehabilitates theologically many profound views more or less forgotten. Nevertheless, we also find that, in this work, the author, after opening new avenues, comes to close them. The status Bouyer gives to Holy Saturday manifests this lack of consistency. (...) The present article attempts to explain this situation. At the end, Bouyer’s own approach appears to be a link between the theologies of Thomas Aquinas and Hans Urs von Balthasar. (shrink)

On trouvera ici la présentation et l’édition de deux brèves questions de l’Ermite de saint Augustin, Jacques de Viterbe. Dans la première question, Jacques s’attache à montrer en quel sens il est légitime de dire que les habitus moraux sont innés. Dans la seconde question, il défend la thèse que les habitus des principes moraux appartiennent de façon plus intime à l’âme que les habitus intellectuels. Comme le Viterbien oppose sa position à celle de Thomas d’Aquin, on tente dans (...) la dernière partie de l’article de cerner les raisons philosophiques du désaccord entre les deux auteurs. (shrink)

Résumé — Alors que, pour Thomas d’Aquin et Gilles de Rome, Dieu peut ajouter à la création une série infinie d’espèces de perfection croissante sans compromettre sa transcendance et sans contrevenir aux lois de la logique, Henri de Gand et Godefroid de Fontaines développent des arguments puissants contre cette même idée, arguant notamment que la production d’une telle série impliquerait une infinité en acte d’idées en Dieu. L’article montre comment, dans son Quodlibet I, q. 2 où il expose et (...) critique systématiquement les arguments de Godefroid et d’Henri, Jacques de Viterbe renoue avec une position proche de celle de Thomas et Gilles.— While Thomas Aquinas and Giles of Rome believed that God could produce an infinite number of increasingly more perfect creatures without threatening his transcendence or breaching the laws of logic, Henry of Ghent and Godfrey of Fontaines argued against that belief, holding that such an ability on God’s part would entail the existence of an actual infinity of ideas in the divine intellect. One author who was to be influenced by Henry’s arguments was Godfrey of Fontaines whose views James of Viterbo refutes in Quodlibet I, q. 2. The article examines the detail of James’s arguments against Godfrey and in favor of the view, much like Thomas’ and Giles’, that God can add to the total amount of perfection in creation. (shrink)

The author’s purpose is to understand the role divine ideas play as causal principles in Aquinas’s philosophy. His contention is that, although Thomas’s doctrine of ideas is perhaps not the key to an understanding of his metaphysics, it is certainly “ a key to such an understanding” .The book is divided into six chapters. The first chapter seeks to provide a general definition of divine ideas according to Aquinas. Divine ideas are exemplar causes in the likeness of which God (...) produces creatures. Ideas in the strict sense belong to God’s practical or actually practical knowledge. The causality exercised by exemplars is that of formal causality, but because they are productive of things, they entail efficient and final causality, as well. In chapter 2, Doolan examines Thomas’s arguments in favor of the existence of divine ideas. Chapter 3 deals with the question of the multiplicity of divine ideas. Doolan first establishes, against Gilson and others, that Aquinas did indeed hold that there was a multiplicity of divine ideas. He then shows how Aquinas was able to reconcile the diversity of ideas with God’s simplicity. The gist of the solution involves viewing ideas as nonbeings relative to God, who is, of course, ipsum esse. Now the only way non-beings can enter into God is in. (shrink)

L'ambition de cet ouvrage est d'illustrer à la fois comment la philosophie conceptualise le conflit et comment elle s'efforce d'en résoudre les dangers inhérents. Plutôt que de proposer un aperçu purement abstrait de la notion de « conflit », l'ensemble des travaux se focalise sur la confrontation des philosophes à des problèmes historiques tels que la guerre, la dissension sociale, la tyrannie, ou encore le sport. -/- .

A review of Thomas Wartenberg's Thoughtful Images: Illustrating Philosophy Through Art (OUP 2023).

ABSTRACTThis paper studies Antoine Le Grand's account of organic identity over time in human bodies. In response to Aristotelian critics who argued that the Cartesian rejection of the Aristotelian ontology of matter and form had put in jeopardy the diachronic identity of material substances in general and of living bodies in particular, Le Grand argued that the identity over time of the human body could be accounted for without the traditional notions of matter and form. The paper shows how (...) he drew on both the Cartesian metaphysics of mind and body and contemporary views on human anatomy and organic generation to develop a unique account of bodily identity over time in human animals. (shrink)

Le Grand's introduction to philosophy, written for use in Cambridge, was the first to be written along Cartesian lines. A section on moral philosophy, first included in the second edition 1672, drew on the common Aristotelian-style way of dealing with the subject-matter, but with modifications inspired by Descartes. In the third edition 1675 this section was almost doubled in size. The additional chapters are an unacknowledged paraphrase of the bulk of Pufendorf's De officio hominis et civis 1673. Le Grand's revision (...) can be taken as a point of transition from an older moral philosophy to modern moral philosophy. It is argued that the contrast between them is not one of virtues vs rules. Rather, the important difference is that the older is essentially eudaimonistic, both in its Aristotelian and Cartesian varieties, but the modern one is not. It relegates the quest for happiness to other disciplines such as psychology, and imports concepts which had belonged to moral theology, such as conscience, imputation, obligation, etc. into moral philosophy. Le Grands für den Gebrauch in Cambridge geschriebene "Einführung in die Philosophie" ist die erste, die nach kartesianischen Richtlinien verfaßt wird. Der Abschnitt über Moralphilosophie, der in die zweite Auflage von 1672 eingefügt wird, ist zwar immer noch in dem gebräuchlichen aristotelischen Stil geschrieben, enthält aber Modifikationen, die von Descartes inspiriert sind. In der dritten Auflage von 1675 wird der Umfang dieses Abschnitts nahezu verdoppelt. Die neu hinzugekommenen Kapitel sind eine Wiedergabe des Hauptteils von Pufendorfs "De officio hominis et civis" von 1673, die als Wiedergabe jedoch nicht kenntlich gemacht wird. Man kann Le Grands Bearbeitung als einen Schritt auf dem Weg von der alten zur modernen Moralphilosophie ansehen. Der Unterschied zwischen beiden ist nicht der Unterschied zwischen der Lehre von den moralischen Tugenden und der von den moralischen Gesetzen. Der entscheidende Unterschied ist vielmehr, daß die ältere Moralphilosophie, sowohl in ihrer aristotelischen, als auch in ihrer kartesianischen Variante, im wesentlichen eudämonistisch ist, während das auf die moderne Moralphilosophie gerade nicht zutrifft. Dadurch wird die Suche nach dem Glück an andere Disziplinen, beispielsweise die Psychologie, verwiesen, während die Moralphilosophie Konzepte wie "Gewissen", "Zurechnung", "Verbindlichkeit" übernimmt, die von der Moraltheologie entwickelt worden waren. (shrink)

Reprint of the first edition. This incisive critique was written around 1807 by Tracy [1754-1836], a French philosopher and path-breaking psychologist who was a friend of Jefferson [1743-1826]. Jefferson saw the Commentary when it was still a manuscript and was so impressed that he took pains to have it printed. He even helped with the translation and corrected the page proofs. Although the translation was published anonymously, we can identify the author and translators through a letter by Jefferson dated January (...) 26, 1811. Elsewhere in this letter he commends it for correcting the Spirit of the Laws. While other studies had merely "nibbled only at its errors...This want is now supplied, and with a depth of thought, recision of idea, of language and of logic, which will force conviction into every mind. I declare to you, Sir, in the spirit of truth and sincerity, that I consider it the most precious gift the present age has received.": The Writings of Thomas Jefferson V:566-571. (shrink)

ABSTRACTFrom 1797 to 1801 a controversy played out on the pages of the Medical Repository, the first scientific journal published in the United States. At its centre was the well-known feud between the followers of Antoine Lavoisier and Joseph Priestley, the lone supporter of the phlogiston model. The American debate, however, had more than two sides. The Americans chemists, Samuel Latham Mitchill and Benjamin Woodhouse, who rushed to support Priestley did not defend his scientific views. Rather, as citizens of (...) a republic, they defended his right to have them. They also castigated the assertions of the “French chemists,” whose claims that the new chemistry obviated debate seemed unsettlingly similar to the dictatorial ambitions of the French state. Using the Medical Repository, Mitchill and Woodhouse sought a compromise that validated the new chemistry, but united it with a more egalitarian form of discourse. The desired balance eluded them. Priestley proved too stubborn, and as the French Revolution descended into dictatorship and war, Mitchill and Woodhouse came more to realize that truly prising French chemistry from the culture of the revolutionary era. The episode left Mitchill and Woodhouse disillusioned with chemistry and hoping to redirect scientific enthusiasm to more pious ends. (shrink)

The Cartesian view that animals are automata sparked a major controversy in early modern European philosophy. This paper studies an early contribution to this controversy. I provide an interpretation of an influential objection to Cartesian animal automatism raised by Ignace-Gaston Pardies (1636–1673). Pardies objects that the Cartesian arguments show only that animals lack ‘intellectual perception’ but do not show that animals lack ‘sensible perception.’ According to Pardies, the difference between these two types of perception is that the former is reflexive (...) such that we both perceive an object and the perception itself, whereas sensible perception lacks this reflexivity. This notion of sensible perception was criticized by the Cartesian Antoine Dilly for violating the doctrine that all thought is conscious. However, I argue that sensible perceptions are not unconscious for Pardies. Rather, they are conscious perceptions that are unaccompanied by a kind of reflexive perception that is constitutive of attention. Moreover, I argue that when understood in this way Pardies raises a compelling objection to Cartesian animal automatists. (shrink)

The article proposes a comparison between the critique that Antoine Arnault (1612-1694) raises against Malebranche’s views on perception and the critique that Thomas Reid (1710-1796) moves against the theory of ideas defended by Berkeley and Hume. Both Arnault and Reid advocate a position according to which our perceptions allow us to have direct knowledge of material objects existing independently of us and not only of representations of them. Arnault proposes different arguments to refute Malebranche. In doing that he (...) doesn’t completely reject the Cartesian representational account of perception. Reid is more radical: in order to refuse Berkeley and Hume he rejects the whole theory of ideas, and focuses instead on the mental powers through which we cognize reality. (shrink)

The article proposes a comparison between the critique that Antoine Arnault (1612-1694) raises against Malebranche’s views on perception and the critique that Thomas Reid (1710-1796) moves against the theory of ideas defended by Berkeley and Hume. Both Arnault and Reid advocate a position according to which our perceptions allow us to have direct knowledge of material objects existing independently of us and not only of representations of them. Arnault proposes different arguments to refute Malebranche. In doing that he (...) doesn’t completely reject the Cartesian representational account of perception. Reid is more radical: in order to refuse Berkeley and Hume he rejects the whole theory of ideas, and focuses instead on the mental powers through which we cognize reality. (shrink)

The epistemology of models has to face a conundrum: models are often described as highly idealised, and yet they are considered to be vehicles for scientific explanations. Truth-oriented—veritist—conceptions of explanation seem thereby undermined by this contradiction. In this article, I will show how this apparent paradox can be avoided by appealing to the notion of fiction. If fictionalism is often thought to lead to various flavours of instrumentalism, thereby weakening the veritist hopes, the fiction view of models offers a framework (...) much richer than it seems at first sight. To do so, I will call upon the concepts of modality, counterfactual structure and credible worlds. In the end, veritism of explanation and fiction can indeed go hand in hand, but the scope of explanations we can hope to draw from models must be more precisely delineated. (shrink)

v. 1. Editorial introduction -- v. 2. The English and Latin texts (i) -- v. 3. The English and Latin texts (ii).

The newly updated Right and Wrong 2nd Edition is an accessible introduction to the major traditions in western philosophical ethics, written in a lively and engaging style. It is designed for entry-level ethics courses and includes real-life ethical scenarios chosen to appeal directly to students. Greatly expanded and improved, this successful text introduces students to the major ethical traditions, and provides a simple methodology for resolving ethical dilemmas Treats teleological and deontological approaches to ethics as the two most important traditions, (...) but now includes chapters on virtue ethics and the ethics of care The very accessible writing style speaks directly to students’ own experience Draws examples from three types of real-life ethical scenarios submitted by students: academic dishonesty, partying, and personal relationships Provides a concise treatment of this notoriously complex subject, perfect for entry-level ethics and applied ethics courses. (shrink)

Schopenhauer’s invective is legendary among philosophers, and is unmatched in the historical canon. But these complaints are themselves worthy of careful consideration: they are rooted in Schopenhauer’s philosophy of language, which itself reflects the structure of his metaphysics. This short chapter argues that Schopenhauer’s vitriol rewards philosophical attention; not because it expresses his critical take on Fichte, Hegel, Herbart, Schelling, and Schleiermacher, but because it neatly illustrates his philosophy of language. Schopenhauer’s epithets are not merely spiteful slurs; instead, they reflect (...) deep-seated theoretical and methodological commitments to transparency of exposition. (shrink)

When making decisions, humans can observe many kinds of information about others' activities, but their effects on performance are not well understood. We investigated social learning strategies using a simple problem-solving task in which participants search a complex space, and each can view and imitate others' solutions. Results showed that participants combined multiple sources of information to guide learning, including payoffs of peers' solutions, popularity of solution elements among peers, similarity of peers' solutions to their own, and relative payoffs from (...) individual exploration. Furthermore, performance was positively associated with imitation rates at both the individual and group levels. When peers' payoffs were hidden, popularity and similarity biases reversed, participants searched more broadly and randomly, and both quality and equity of exploration suffered. We conclude that when peers' solutions can be effectively compared, imitation does not simply permit scrounging, but it can also facilitate propagation of good solutions for further cumulative exploration. (shrink)

The paper presents a research programme for the neuroscience of consciousness called 'neurophenomenology' and illustrates it with a recent pilot study . At a theoretical level, neurophenomenology pursues an embodied and large-scale dynamical approach to the neurophysiology of consciousness . At a methodological level, the neurophenomenological strategy is to make rigorous and extensive use of first-person data about subjective experience as a heuristic to describe and quantify the large-scale neurodynamics of consciousness . The paper focuses on neurophenomenology in relation to (...) three challenging methodological issues about incorporating first-person data into cognitive neuroscience: first-person reports can be biased or inaccurate; the process of generating first-person reports about an experience can modify that experience; and there is an 'explanatory gap' in our understanding of how to relate first-person, phenomenological data to third-person, biobehavioural data. (shrink)

Laboratoire de Neurosciences Cognitives et Imagerie Ce´re´brale (LENA), Hoˆpital de La Salpeˆtrie`re, Centre National de la Recherche Scientifique (CNRS).

This paper analyzes an explicit instantiation of the program of “neurophenomenology” in a neuroscientific protocol. Neurophenomenology takes seriously the importance of linking the scientific study of consciousness to the careful examination of experience with a specific first-person methodology. My first claim is that such strategy is a fruitful heuristic because it produces new data and illuminates their relation to subjective experience. My second claim is that the approach could open the door to a natural account of the structure of human (...) experience as it is mobilized in itself in such methodology. In this view, generative passages define the type of circulation which explicitly roots the active and disciplined insight the subject has about his/her experience in a biological emergent process. (shrink)

_sciousness called ‘neurophenomenology’ (Varela 1996) and illustrates it with a_ _recent pilot study (Lutz et al., 2002). At a theoretical level, neurophenomenology_ _pursues an embodied and large-scale dynamical approach to the_ _neurophysiology of consciousness (Varela 1995; Thompson and Varela 2001;_ _Varela and Thompson 2003). At a methodological level, the neurophenomeno-_ _logical strategy is to make rigorous and extensive use of first-person data about_ _subjective experience as a heuristic to describe and quantify the large-scale_ _neurodynamics of consciousness (Lutz 2002). The paper (...) foocuses on_ _neurophenomenology in relation to three challenging methodological issues_ _about incorporating first-person data into cognitive neuroscience: (i) first-person_ _reports can be biased or inaccurate; (ii) the process of generating first-person_ _reports about an experience can modify that experience; and (iii) there is an ‘ex-_ _planatory gap’ in our understanding of how to relate first-person, phenomeno-_ _logical data to third-person, biobehavioural data._. (shrink)

Recent brain imaging studies using functional magnetic resonance imaging (fMRI) have implicated insula and anterior cingulate cortices in the empathic response to another’s pain. However, virtually nothing is known about the impact of the voluntary generation of compassion on this network. To investigate these questions we assessed brain activity using fMRI while novice and expert meditation practitioners generated a loving-kindness-compassion meditation state. To probe affective reactivity, we presented emotional and neutral sounds during the meditation and comparison periods. Our main hypothesis (...) was that the concern for others cultivated during this form of meditation enhances affective processing, in particular in response to sounds of distress, and that this response to emotional sounds is modulated by the degree of meditation training. The presentation of the emotional sounds was associated with increased pupil diameter and activation of limbic regions (insula and cingulate cortices) during meditation (versus rest). During meditation, activation in insula was greater during presentation of negative sounds than positive or neutral sounds in expert than it was in novice meditators. The strength of activation in insula was also associated with self-reported intensity of the meditation for both groups. These results support the role of the limbic circuitry in emotion sharing. The comparison between meditation vs. rest states between experts and novices also showed increased activation in amygdala, right temporo-parietal junction (TPJ), and right posterior superior temporal sulcus (pSTS) in response to all sounds, suggesting, greater detection of the emotional sounds, and enhanced mentation in response to emotional human vocalizations for experts than novices during meditation. Together these data indicate that the mental expertise to cultivate positive emotion alters the activation of circuitries previously linked to empathy and theory of mind in response to emotional stimuli.. (shrink)