We hypothesize that life began not with the first self‐reproducing molecule or metabolic network, but as a prebiotic ecology of co‐evolving populations of macromolecular aggregates (composomes). Each composome species had a particular molecular composition resulting from molecular complementarity among environmentally available prebiotic compounds. Natural selection acted on composomal species that varied in properties and functions such as stability, catalysis, fission, fusion and selective accumulation of molecules from solution. Fission permitted molecular replication based on composition rather than linear structure, while fusion (...) created composomal variability. Catalytic functions provided additional chemical novelty resulting eventually in autocatalytic and mutually catalytic networks within composomal species. Composomal autocatalysis and interdependence allowed the Darwinian co‐evolution of content and control (metabolism). The existence of chemical interfaces within complex composomes created linear templates upon which self‐reproducing molecules (such as RNA) could be synthesized, permitting the evolution of informational replication by molecular templating. Mathematical and experimental tests are proposed. BioEssays 28: 399–412, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

New concepts may prove necessary to profit from the avalanche of sequence data on the genome, transcriptome, proteome and interactome and to relate this information to cell physiology. Here, we focus on the concept of large activity-based structures, or hyperstructures, in which a variety of types of molecules are brought together to perform a function. We review the evidence for the existence of hyperstructures responsible for the initiation of DNA replication, the sequestration of newly replicated origins of replication, cell division (...) and for metabolism. The processes responsible for hyperstructure formation include changes in enzyme affinities due to metabolite-induction, lipid-protein affinities, elevated local concentrations of proteins and their binding sites on DNA and RNA, and transertion. Experimental techniques exist that can be used to study hyperstructures and we review some of the ones less familiar to biologists. Finally, we speculate on how a variety of in silico approaches involving cellular automata and multi-agent systems could be combined to develop new concepts in the form of an Integrated cell (I-cell) which would undergo selection for growth and survival in a world of artificial microbiology. (shrink)

Do fictions depend upon imagination? Derek Matravers argues against the mainstream view that they do, and offers an original account of what it is to read, listen to, or watch a narrative. He downgrades the divide between fiction and non-fiction, largely dispenses with the imagination, and in doing so illuminates a succession of related issues.

Matravers examines how emotions form the bridge between our experience of art and of life. We often find that a particular poem, painting, or piece of music carries an emotional charge; and we may experience emotions toward, or on behalf of, a particular fictional character. Matravers shows that what these experiences have in common, and what links them to the expression of emotion in non-artistic cases, is the role played by feeling. He carries out a critical survey of various accounts (...) of the nature of fiction, attacks contemporary cognitivist accounts of expression, and offers an uncompromising defense of a controversial view about musical expression: that music works by expressing the emotions it causes its listeners to feel. (shrink)

Traversing the fields of pedagogy, philosophy, and political theory, this book develops a marxist theory of education that will be useful for academics and activists alike. The second edition includes two additional chapters as well as a new preface and revisions throughout.

Challenging, with several powerful arguments, some of our deepest beliefs about rationality, morality, and personal identity, Parfit claims that we have a false view about our own nature. It is often rational to act against our own best interersts, he argues, and most of us have moral views that are self-defeating. We often act wrongly, although we know there will be no one with serious grounds for complaint, and when we consider future generations it is very hard to avoid conclusions (...) that most of us will find very disturbing. (shrink)

It’s intuitive to think that an intentional action requires that the agent knows that she’s doing so. In light of some apparent counterexamples, Setiya suggests that this intuitive insight is better captured in terms of credence: performing an intentional action requires the agent to have a higher credence that she’s doing so than she would have otherwise. I argue that there is no such thing as an agent’s credence for what she’s doing. After distinguishing this thesis from an idea some (...) defend under the slogan “deliberation crowds out prediction”, I explore the thesis’s broader epistemological implications for the belief-credence relation. (shrink)

This book presents an accessible and groundbreaking new look at the evolution of consciousness. It traces its origins back to early man's primordial emotions - those elicited from basic needs such as hunger and thirst.

Mengzi states that our human nature consists of our ability to feel compassion, disdain, respect, and (dis-)approval: all human beings have them. But he also states that we lose these four emotional capacities if we don’t reflect on or attend to them. There is an apparent contradiction in saying that all humans have them, but some have lost them. This essay offers a close reading of Mengzi’s phrase “to lose it” that helps explain away this appearance of contradiction. In doing (...) so, Mengzi is interpreted to be offering an ethics of attention about how we should attend to ourselves and others selectively to have a functional social life. (shrink)

This paper argues that, with certain provisos, predicting one's future actions is incompatible with rationally deliberating about whether to perform those actions. It follows that fully rational omniscient agents are impossible, since an omniscient being could never rationally deliberate about what to do. Consequently, theories that explain practical reasons in terms of the choices of a perfectly rational omniscient agent must fail. The paper considers several ways of defending the possibility of an omniscient agent, and concludes that while some of (...) these may work, they are inconsistent with the aim of explaining practical normativity by appeal to such an agent. (shrink)

This is a major work in moral philosophy, the long-awaited follow-up to Parfit's 1984 classic Reasons and Persons, a landmark of twentieth-century philosophy. Parfit now presents a powerful new treatment of reasons and a critical examination of the most prominent systematic moral theories, leading to his own ground-breaking conclusion.

There are many different oughts. There is a moral ought, a prudential ought, an epistemic ought, the legal ought, the ought of etiquette, and so on. These oughts can prescribe incompatible actions. What I morally ought to do may be different from what I self-interestedly ought to do. Philosophers have claimed that these conflicts are resolved by an authoritative ought, or by facts about what one ought to do simpliciter or all-things-considered. However, the only coherent notion of an ought simpliciter (...) has preposterous first-order normative commitments. It is more reasonable to reject the ought simpliciter in favor of the form of normative pluralism advocated in (Tiffany 2007). (shrink)

In the first monograph on Lyotard and education, Derek R. Ford approaches Lyotard's thought as pedagogical in itself. The result is a novel, soft, and accessible study of Lyotard organized around two inhuman educations: that of "the system" and that of "the human." The former enforces an interminable process of development, dialogue and exchange, while the latter finds its force in the mute, secret, opaque, and inarticulable. Threading together a range of Lyotard's work through four pedagogical processes-reading, writing, voicing, (...) and listening-the author insists on the distinct educational logics that can uphold or interrupt different ways of being-together in the world, touching on a range of topics from literacy and aesthetics to time and political-economy. While Inhuman Educations can serve as an introduction to Lyotard's philosophy, it also constitutes a singular, provocative, and fresh take on his thought. (shrink)

For Malraux, modernity in art is not only about modern art; it is also about the birth of what he aptly terms “the first universal world of art.” This event was a consequence of the process of metamorphosis which is central to Malraux’s account of the relationship between art and time. The article explains this event, noting also that modern aesthetics has not provided an explanation. (This is the English version of the final which will be in French.).

Derek Parfit presents the third volume of On What Matters, his landmark work of moral philosophy. Parfit develops further his influential treatment of reasons, normativity, the meaning of moral discourse, and the status of morality. He engages with his critics, and shows the way to resolution of their differences.

Ethics for Robots describes and defends a method for designing and evaluating ethics algorithms for autonomous machines, such as self-driving cars and search and rescue drones. Derek Leben argues that such algorithms should be evaluated by how effectively they accomplish the problem of cooperation among self-interested organisms, and therefore, rather than simulating the psychological systems that have evolved to solve this problem, engineers should be tackling the problem itself, taking relevant lessons from our moral psychology. Leben draws on the (...) moral theory of John Rawls, arguing that normative moral theories are attempts to develop optimal solutions to the problem of cooperation. He claims that Rawlsian Contractarianism leads to the 'Maximin' principle - the action that maximizes the minimum value - and that the Maximin principle is the most effective solution to the problem of cooperation. He contrasts the Maximin principle with other principles and shows how they can often produce non-cooperative results. Using real-world examples - such as an autonomous vehicle facing a situation where every action results in harm, home care machines, and autonomous weapons systems - Leben contrasts Rawlsian algorithms with alternatives derived from utilitarianism and natural rights libertarianism. Including chapter summaries and a glossary of technical terms, Ethics for Robots is essential reading for philosophers, engineers, computer scientists, and cognitive scientists working on the problem of ethics for autonomous systems. (shrink)

Thomas Reid (1710–96) is increasingly being seen as a highly significant philosopher and a central figure in the Scottish Enlightenment. This new edition of Reid's classic philosophical text in the philosophy of mind at long last gives scholars a complete, critically edited text of the Inquiry. The critical text is based on the fourth life-time edition (1785). A selection of related documents showing the development of Reid's thought, textual notes, bibliographical details of previous editions and a full introduction by the (...) editor makes this an important contribution to the study of this increasingly respected philosopher. -/- Key Features - Complete, critically edited text of the Inquiry accompanied by a judicious selection of manuscript evidence relating to its composition - Comprehensive Introduction providing an historical and philosophical account of the formation of the Inquiry - Detailed textual notes which include bibliographical details and allusions, translations, references to secondary literature and selected passages from Reid's manuscripts. (shrink)

An argument against the bias towards the near; how a defence of temporal neutrality is not a defence of S; an appeal to inconsistency; why we should reject S and accept CP.

This is Thomas Reid's greatest work. It covers far more philosophical ground than the earlier, more popular Inquiry. The Intellectual Powers and its companion volume, Essays on the Active Powers of Man, constitute the fullest, most original presentation of the philosophy of Common Sense. In the process, Reid provides acutely critical discussions of an impressive array of thinkers but especially of David Hume. In Reid's eyes, Hume had driven a deep tendency in modern philosophy to its ultimate conclusions by creating (...) a phantom-world of so-called 'ideas' that sprang from objects of observation; the self was a conglomeration of perceived ideas; and the will as the source of action was nothing but the balance of passionate impulses. -/- Reid's Common Sense philosophy answers these problems by suggesting that sceptics, such as Hume, unavoidably affirm what they purport to deny, namely the existence of a stable external world, of other minds, of the continuity of their own minds, and of their own and other people's ability to ascribe and accept responsibility for actions. We can understand all of this by proper empirical observation and philosophical analysis of the activity of the mind. Reid's major positive contribution to philosophy is a detailed account of the various innate powers of the mind. While particularly influential in the first half of the nineteenth century, Reid's work has retained a significant role in philosophy, not least in recent years. At the same time, his role in the Scottish Enlightenment is becoming much better understood. -/- This is the only properly established text. It is accompanied by manuscript lectures on the nature and immortality of the soul, as well as helpful editorial annotation and introduction, making it useful to a wide variety of readers. -/- Key Features: -/- Accurate, reliable and critically established text; The Introduction explains the work's genesis and its place in Reid's system; Annotations provide an understanding of Reid's context; An Appendix contains manuscript material covering an important topic not represented in the hitherto published work. (shrink)

This paper discusses varieties of normative phenomena, ranging from morality, to epistemic justification, to the rules of chess. It canvases a number of distinctions among these different normative phenomena. The most significant distinction is between formal and authoritative normativity. The prior is the normativity exhibited by any standard one can meet or fail to meet. The latter is the sort of normativity associated with phenomena like the "all-things-considered" ought. The paper ends with a brief discussion of reasons for skepticism about (...) authoritative normativity. (shrink)

According to Bickerton, the behavioral sciences have failed to give an adequate account of human nature at least partly because of the conjunction and mutual reinforcement of two widespread beliefs: that language is simply a means of communication and that human intelligence is the result of the rapid growth and unusual size of human brains. Bickerton argues that each of the properties distinguishing human intelligence and consciousness from that of other animals can be shown to derive straightforwardly from properties of (...) language. In essence, language arose as a representational system, not a means of communication or a skill, and not a product of culture but an evolutionary adaptation. The author stresses the necessity of viewing intelligence in evolutionary terms, seeing it not as problem solving but as a way of maintaining homeostasis - the preservation of those conditions most favorable to an organism, the optimal achievable conditions for survival and well-being. The term protolanguage is used to describe the stringing together of symbols that prehuman hominids employed. "It did not allow them to turn today's imagination into tomorrow's fact. But it is just this power to transform imagination into fact that distinguishes human behavior from that of our ancestral species, and indeed from that of all other species. It is exactly what enables us to change our behavior, or invent vast ranges of new behavior, practically overnight, with no concomitant genetic changes." Language and Human Behavior should be of interest to anyone in the behavioral and evolutionary sciences and to all those concerned with the role of language in human behavior. (shrink)

Autonomous vehicles must be programmed with procedures for dealing with trolley-style dilemmas where actions result in harm to either pedestrians or passengers. This paper outlines a Rawlsian algorithm as an alternative to the Utilitarian solution. The algorithm will gather the vehicle’s estimation of probability of survival for each person in each action, then calculate which action a self-interested person would agree to if he or she were in an original bargaining position of fairness. I will employ Rawls’ assumption that the (...) Maximin procedure is what self-interested agents would use from an original position, and then show how the Maximin procedure can be operationalized to produce unique outputs over probabilities of survival. (shrink)

Scientists often make surprising claims about things that no one can observe. In physics, chemistry, and molecular biology, scientists can at least experiment on those unobservable entities, but what about researchers in fields such as paleobiology and geology who study prehistory, where no such experimentation is possible? Do scientists discover facts about the distant past or do they, in some sense, make prehistory? In this book Derek Turner argues that this problem has surprising and important consequences for the scientific (...) realism debate. His discussion covers some of the main positions in philosophy of science - realism, social constructivism, empiricism, and the natural ontological attitude - and shows how they relate to issues in paleobiology and geology. His original and thought-provoking book will be of wide interest to philosophers and scientists alike. (shrink)

John Dewey’s philosophical pragmatism offers a reformatory approach to the arduous relationship between natural sciences and humanities. The crucial issue, which Dewey sets himself to resolve, is the pre-Darwinian influence of classical philosophy upon various scholarly practices. Ancient background assumptions still today permeate a considerable proportion of academic research and argumentation on both sides of the debate. Even evolutionary accounts appear to be affected. In order to avoid the often implicit, but nonetheless problematic, consequences that ensue from such archaic premises, (...) I examine Dewey’s reappraisal of the concepts of art, science and knowledge. An analysis of these key concepts renders it possible to understand the proper function of aesthetic experience. In this paper, natural constitution of an aesthetic experience, which carries one of the intrinsic relations between art and science, comprises the core of the proposed solution. Furthermore, establishment of an integral aesthetic connection forms a fruitful basis for further bridging of the gap between hard sciences and humanities. (shrink)

It is generally acknowledged that confabulation undermines the authority of self-attribution of mental states. But why? The mainstream answer is that confabulation misrepresents the actual state of one’s mind at some relevant time prior to the confabulatory response. This construal, we argue, rests on an understanding of self-attribution as first-person mindreading. Recent developments in the literature on folk psychology, however, suggest that mental state attribution also plays an important role in regulating or shaping future behaviour in conformity with normative expectations. (...) We explore an analogue understanding of self-attribution of mental states in terms of first-person mindshaping. The main aim of this paper is to explore how this insight alters the implications of empirical confabulation studies on first-person authority. We also indicate how this sheds new light on the phenomenon of confabulation itself. (shrink)

Air is an immersive substance that envelopes us and binds us together, yet it has dominantly been taken for granted and left out of educational and other theorizations. This article develops a conceptualization of the pneumatic common in order to address this gap. The specific intervention staged is within recent educational literature on the common by Noah De Lissovoy, Tyson E. Lewis, and Alexander Means. This literature is surveyed and analyzed in relation to educational theory, curriculum, pedagogy, and policy. Claiming (...) that the air is a central feature of and paradigm for the common, I then concentrate on making the air conditions of the educational common explicit. I do this through a theoretical, historical, and sociological reading of air conditioning. While this explicitation is itself educational, I return to the educational common at the end of the article to ask how and what we can learn in, with, and from the air. (shrink)

In a world of limited resources, it could be argued that companies that aspire to be good corporate citizens need to focus on making best use of resources. User value and environmental harm are created in supply chains and it could therefore be argued that company business ethics should be extended from the company to the entire value chain from the first supplier to the last customer. Starting with a delineation of the linkages between business ethics, corporate sustainability, and the (...) stakeholder concept, this article argues that supply chains generally have a great innovation potential for sustainable development. This potential could be highlighted with system thinking and the use of change management knowledge, promoting not only innovations within technology but also within organizational improvement. We propose process models and performance indicators as means of highlighting improvement potential and thus breaking down normative business ethics' requirements to an opertionalizable corporate level: Good business ethics should focus on maximizing stakeholder value in relation to harm done. Our results indicate that focusing on supply chains reveals previously unknown innovation potential that seems to be related to limited system understanding. The assumption is that increased visibility of opportunities will act as a driver for change. Results also highlight the importance of focusing on sustainability effects of the core business and clearly relating value created to harm done. (shrink)

Gender is commonly thought of as dependent on sex even though there are occasional aberrations. Interviews with female-to-male trans people, however, suggest that sex and sex characteristics can be understood as expressions of gender. The expression of gender relies on both behavior and the appearance of the performer as male or female. When sex characteristics do not align with gender, behavior becomes more important to gender expression and interpretation. When sex characteristics become more congruent with gender, behavior becomes more fluid (...) and less important in asserting gender. Respondents also challenge traditional notions of sexual orientation by focusing less on the sex of the partner and more on the gender organization of the relationship. The relationship’s ability to validate the interviewee’s masculinity or maleness often takes precedence over the sex of the partner, helping to explain changing sexual orientation as female-to-male transsexual and transgendered people transition into men. (shrink)

(Post)apartheid Conditions: Psychoanalysis and Social Formation advances a series of psychoanalytic perspectives on contemporary South Africa, exploring key psychosocial topics such as space-identity, social fantasy, the body, whiteness, memory and nostalgia.

Climate change is a product of the entire social and economic system within which we exist, in a word, capitalism.

This book is intended for undergraduate courses in social theory for second and third year sociology students, as well as postgraduate and academic researchers.

We can start with some science fiction. Here on Earth, I enter the Teletransporter. When I press some button, a machine destroys my body, while recording the exact states of all my cells. This information is sent by radio to Mars, where another machine makes, out of organic materials, a perfect copy of my body. The person who wakes up on Mars seems to remember living my life up to the moment when I pressed the button, and is in every (...) other way just like me. (shrink)

In the wake of the paleobiological revolution of the 1970s and 1980s, paleontologists continue to investigate far-reaching questions about how evolution works. Many of those questions have a philosophical dimension. How is macroevolution related to evolutionary changes within populations? Is evolutionary history contingent? How much can we know about the causes of evolutionary trends? How do paleontologists read the patterns in the fossil record to learn about the underlying evolutionary processes? Derek Turner explores these and other questions, introducing the (...) reader to exciting recent work in the philosophy of paleontology and to theoretical issues including punctuated equilibria and species selection. He also critically examines some of the major accomplishments and arguments of paleontologists of the last 40 years. (shrink)

Suppose we discover how we could live for a thousand years, but in a way that made us unable to have children. Everyone chooses to live these long lives. After we all die, human history ends, since there would be no future people. Would that be bad? Would we have acted wrongly? Some pessimists would answer No. These people are saddened by the suffering in most people’s lives, and they believe it would be wrong to inflict such suffering on others (...) by having children. In earlier centuries, this bleak view was fairly plausible. But our successors would be able to prevent most human suffering. Some optimists would also answer No . . . These [views] are, I believe, deeply mistaken. Given what our successors could achieve in the next million or billion years, here and elsewhere in our galaxy, it would be likely to be very much worse if there were no future people. (shrink)

When we have a normative reason, and we act for that reason, it becomes our motivating reason. But we can have either kind of reason without having the other. Thus, if I jump into the canal, my motivating reason was provided by my belief; but I had no normative reason to jump. I merely thought I did. And, if I failed to notice that the canal was frozen, I had a reason not to jump that, because it was unknown to (...) me, did not motivate me. Though we can have normative reasons without being motivated, and vice versa, such reasons are closely related to our motivation. There are, however, very different views about what this relation is. This disagreement raises wider questions about what normative reasons are, and about which reasons there are. After sketching some of these views, I shall discuss some arguments by Williams, and then say where, in my opinion, the truth lies. [...] I [will] suggest why, as I believe, we should be non-reductive normative realists, and should regard all reasons as external. (shrink)

According to the Repugnant Conclusion: Compared with the existence of many people who would all have some very high quality of life, there is some much larger number of people whose existence would be better, even though these people would all have lives that were barely worth living. I suggest some ways in which we might be able to avoid this conclusion. I try to defend a strong form of lexical superiority.