How exactly is accepting the bad side effects of good choices morally defensible? The best defense to date is by Joseph Boyle, John Finnis, and Germain Grisez and relies on the claim that bad side effects are unavoidable. But are they? Three accounts of why bad side effects are unavoidable—one by John Zeis, a second by Boyle, Finnis, and Grisez jointly, and a third by Boyle independently—are examined and rejected. Next, an alternative proposal which suggests bad side effects are (...) always avoidable is also examined and rejected. Finally, an adequate account of why bad side effects are unavoidable is presented and defended. This defense relies on certain facts about the goods which human agents ultimately find fulfilling and about human agents’ attempts to instantiate those goods through various projects. (shrink)

Each contributor to this book has used personal experience as the basis from which to frame his individual sociological perspectives. Because they have personalized their work, their accounts are real, and recognizable as having come from 'real' persons, about 'real' experiences. There are no objectively-distanced disembodied third person entities in these accounts. These writers are actual people whose stories will make you laugh, cry, think, and want to know more.

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

The contingentist/inevitabilist debate contests whether the results of successful science are contingent or inevitable. This article addresses lingering ambiguity in the way contingency is defined in this debate. I argue that contingency in science can be understood as a collection of distinct concepts, distinguished by how they hold science contingent, by what elements of science they hold contingent, and by what those elements are contingent upon. I present a preliminary taxonomy designed to characterize the full-range positions available and illustrate that (...) these constitute a diverse array rather than a spectrum. (shrink)

Much of the recent discussion of problematic aspects of quantum-mechanical measurement centers around that feature of quantum theory which is called "the projection postulate." This is roughly the claim that a change of a certain sort occurs in the state of a physical system when a measurement is made on the system. In this paper an argument for the projection postulate due to von Neumann is considered. Attention is focused on trying to provide an understanding of the notion of "the (...) state of a physical system" which is compatible with the argument von Neumann offers. An attempt is made to formulate the argument in terms of an objectivistic interpretation of probability concepts. It is seen that such an interpretation does not provide a suitable way of understanding the argument. An attempt is made to illustrate the source of this failure in terms of a non-quantum-mechanical example. (shrink)

In the Theodicy, Leibniz argues against two impious conceptions of God—a God who makes arbitrary choices and a God who doesn’t make choices at all. Many interpret Leibniz as navigating these dangers by positing a kind of non-Spinozistic necessitarianism. I examine passages from the Theodicy which reject not only blind necessitarianism but necessitarianism altogether. Leibniz thinks blind necessitarianism is dangerous due to the conception of God it entails and the implications for morality. Non-Spinozistic necessitarianism avoids many of these criticisms. Leibniz (...) finds that even necessary actions should receive certain rewards and punishments as long as they necessarily lead to a change in future behavior. But Leibniz rejects even non-Spinozistic necessitarianism on the grounds that it is inconsistent with punitive justice. Whether Leibniz successfully avoids necessitarianism, it ought to be clear that he sees his own position as significantly distinct from necessitarianism and not just Spinozism. (shrink)

In popular opinion, Leibniz’s work on the problem of evil is thought to begin and end with the claim that this is the best of all possible worlds, as if this were all that Leibniz needed to defend the justice of God. In many places, however, Leibniz is concerned to remove from God the actual agency for the evils in the world. By examining Leibniz’s uses of the concept of divine permission, one might find a Leibniz for whom the best-possible-world (...) thesis answers only some of the difficulties regarding God’s relationship to the evils in the world. Leibniz introduces permission early in his career, in the manuscript dialogue, Confessio philosophi, written in the early 1670s. Two and a half decades later, Pierre Bayle offered a critique of traditional uses of permission in his Dictionnaire historique et critique. Though he certainly had not read Leibniz’s manuscript, the arguments against the use of permission in the Dictionnaire offer a useful foil for understanding the role permission plays in Leibniz’s early thought. Bayle’s objections will be discussed first. Once these are explained, they will be used to argue that Leibniz’s doctrine of permission, as presented in the Confessio philosophi, adds nothing to the best-possible-world thesis. As the reasons for this are explained, it will become obvious that this is not the case for the mature Leibniz of the Essais de Théodicée. Thus, there is a Leibniz for whom the best-possible-world thesis answers only some of the theological problems posed by evil, but that is not the Leibniz of the early Confessio philosophi. (shrink)

Leibniz’s Confessio philosophi (1672–1673) appears to provide an anti-necessitarian solution to the problem of the author of sin. I will give here a brief reading of what appear to be two solutions to the problem of the author of sin in the Confessio. The first solution appears to commit Leibniz’s spokesman (the Philosopher) to necessitarianism. The Theologian (Leibniz’s interlocutor) objects to this necessitarianism, prompting the Philosopher to offer a modified version that appears to exorcise this doctrine. As it turns out, (...) Leibniz holds that these two solutions are in fact the same. I will thus conclude by reconciling these solutions, arguing for giving priority to the more radical first solution. I will argue for this by looking at the connections between the Confessio philosophi and some of Leibniz’s other works in its genre around its time. It will be argued that Leibniz does not find the necessitarianism, which references to per se contingencies are supposed to solve, to be problematic in 1673. (shrink)

Solid state physics, the study of the physical properties of solid matter, was the most populous subfield of Cold War American physics. Despite prolific contributions to consumer and medical technology, such as the transistor and magnetic resonance imaging, it garnered less professional prestige and public attention than nuclear and particle physics. Solid State Insurrection argues that solid state physics was essential to securing the vast social, political, and financial capital Cold War physics enjoyed in the twentieth century. Solid state’s technological (...) bent, and its challenge to the “pure science” ideal many physicists cherished, helped physics as a whole respond more readily to Cold War social, political, and economic pressures. Its research kept physics economically and technologically relevant, sustaining its cultural standing and policy influence long after the sheen of the Manhattan Project had faded. (shrink)

The industrial border region between Mexico and the USA is notorious for its physical, social and moral squalor. But is it entirely a matter of total exploitation or is the answer to the title’s question more complex than a simple yes? The author is completing his MBA degree at London Business School, is an American citizen and has a background as a consultant in information technology.

The theory of subjective probability and utility recently proposed by professor richard jeffrey has several unique features and appears to be in some ways distinctly more satisfactory than earlier theories. There is, However, One very important class of decision problems which is not discussed by professor jeffrey--Problems concerned with decisions about strategies for using information. The principal task of this paper is to point out some questions which arise in attempting to deal with these decision problems within jeffrey's theory. To (...) do this it will be necessary to examine in some detail jeffrey's discussion of the relation between his theory and those of ramsey and savage. (shrink)

Descartes’s very brief explanations of human responsibility for sin and divine innocence of sin include references to the idea that evil is a privation rather than a real thing. It is not obvious, though, that privation fits naturally in Descartes’s reductionistic metaphysics, nor is it clear precisely what role his privation doctrine plays in his theodicy. These issues are made clear by contrasting Descartes’s use of privations with that of Suarez, particularly in light of reoccurring objections to privation theory. These (...) objections have no weight against Suarez’s use of privations, but Descartes’s mentions of privation are so few that it is not clear how his account avoids their consequences. Descartes’s brevity seems to have motivated some of his followers to develop creative accounts of the way in which privation fits in a Cartesian system. Pierre-Sylvain Régis accomplishes this task by reintroducing material causation. Régis holds that moral evil has no efficient cause since an efficient cause can only produce something real. Because he holds that moral evil can have a material cause, he is able to affirm that the soul is morally responsible for sin. In Régis’s case, accommodating this theological issue meant reincorporating Aristotelian resources into his Cartesian system. (shrink)

Gilbert and Mulkay, in their paper ‘Experiments Are the Key’, present responses of scientists to questions about the development of the chemiosmotic hypothesis of energy coupling in oxidative and photophosphorylation, and infer from these responses both the meaninglessness of the concept ‘key experiment’ and the hopelessness of searching for any data as a bedrock for historical analysis. Gilbert and Mulkay's nihilism is, however, rooted in a lack of understanding of the specific scientific issues involved. A closer look at a proposed (...) ‘key experiment’ shows certain obvious characteristics that could be criteria for a ‘key experiment’ moreover, the actual scientific response to that experiment demonstrates its pivotal role in the development of the field. Instead of demonstrating the lack of empirical bases for scientific judgment, Gilbert and Mulkay demonstrate the necessity for identifying the crucial issues and pursuing them, in questioning the scientists as well as in examining other sources. (shrink)

Recent stories of corporate insiders avoiding losses and, in some cases, generating enormous personal profits as their companies crumbled have led investors to question the integrity of American business and the fairness of the United States stock markets. The SEC tries to ensure the fairness of the stock markets by making and enforcing laws against unfair practices such as insider trading. In the United States, when insiders trade stock based on non-public information, they have broken the law and betrayed the (...) trust that has been placed in them.This study used student subjects to test the relationship between the likelihood of trading based on insider information and subjective probabilities of deterrents and motivations for insider trading. Expected gain, guilt, cynicism, and fairness of laws were the determinants that had a significant relationship with the intent to trade based on insider information. This study also found support for prospect theory with regard to insider trading. The results indicate that subjects are more likely to trade based on insider information to avoid a loss than to achieve an abnormal gain. The study also finds evidence of social desirability response bias. (shrink)

This article examines the interpretive dimensions of human action. Although it takes the reflexive sociology of Pierre Bourdieu as its starting point, the article attempts to develop a more robust hermeneutical account of the reflexivity of social actors and those who study them than Bourdieu himself has considered. It is argued that interpretation is best understood not as the homologous expression of inculcated structures but rather as context-sensitive and reflexively context-transforming action—or what the author wishes to characterize, respectively, as first- (...) and second-order thematizations of embeddedness. The article concludes by contrasting the author's position with the thick description of Clifford Geertz. (shrink)

Why do similar scientific enterprises garner unequal public approbation? High energy physics attracted considerable attention in the late-twentieth-century United States, whereas condensed matter physics – which occupied the greater proportion of US physicists – remained little known to the public, despite its relevance to ubiquitous consumer technologies. This paper supplements existing accounts of this much remarked-upon prestige asymmetry by showing that popular emphasis on the mundane technological offshoots of condensed matter physics and its focus on human-scale phenomena have rendered it (...) more recondite than its better-known sibling field. News reports about high energy physics emphasize intellectual achievement; reporting on condensed matter physics focuses on technology. And whereas frontier-oriented rhetoric of high energy physics communicates ideals of human potential, discoveries that smack of the mundane highlight human limitations and fail to resonate with the widespread aspirational vision of science – a consequence I call “the purloined letter effect.”. (shrink)

A major theme in biological research is the quest for mechanism, embodied in explanatory reductionism: the interpretation of phenomena through links to the entities and laws of more fundamental sciences. For example, the form of Starling's Law of the Heart, relating contractile force to heart volume, follows from the sliding-filament hypothesis of muscle contraction, a molecular concept. Although alternative mechanisms for muscle contraction and cardiac regulation could be deduced from biochemical principles, the formulation provides clear correspondence with the phenomena and (...) a deeper understanding of cardiac function. Moreover, even if the reduction provides no better formulation of the phenomenon, of the macro-regularity, it is still prized as a nearer approach to physical reality, as a step toward realizing fundamental unities and codifying general principles, and as a door to new experimental opportunities. (shrink)

Ulrich Beck characterized the transition from modern to late modern society as a shift from an industrial to a “risk society.” Contemporary society is challenged by negative side effects of modernization, including the increasing and imminent threat of global climate change. This article will test the validity of conceivable prescriptive elements associated with this sociological theory. In doing so, it will focus on the most recent legal developments aimed at tackling climate change within the EU. This paper finds that the (...) precautionary approach is unable to sufficiently shape balanced legal intervention in this day and age. However, the approach adopted by the EU appears to be more successful in this respect. (shrink)

In this response to Paul Gaffney’s “The Nature and Meaning of Teamwork,” I draw on recent work in analytic social philosophy to provide a more robust vocabulary for understanding teamwork as a distinctly social fact. I argue that teamwork entails complex reflexive social cooperation aimed at achieving shared excellence within constraints of various kinds.

It is argued that John Rawls’ theory of social justice as well as the contract argument for it are misleading, if not actually mistaken, in that they appear to take institutional features of societies as fundamental objects of moral evaluation. An alternative view: is expounded. Principles involving institutional features are only contingently related to principles involving the distribution of things people care about. These distributions are taken as the fundamental objects of moral evaluation. Social, political and economic institutions are means (...) to achieve more desirable distributions. It is argued that the alternative provides a more accurate reconstruction of the moral foundations of social-democratic liberalism than does Rawls’ theory. (shrink)

ABSTRACT This paper seeks to develop a philosophical framework for what I argue are the Nietzschean and Kantian aspects of professional boxing matches: narrative dissimulation and moral obligation. The overarching objective of the analysis is to shed a critical light on brief intervals of boxing competitions (the minute between rounds) that are crucial but often overlooked in the philosophical literature devoted to boxing and, indeed, combat sport more generally. Additionally, in characterizing more fully the philosophical complexities of cornerman and boxer (...) interactions in the flow of such a violent and dangerous sport, the analysis aims to make explicit some of what is unique—and uniquely problematic—to competing in and coaching professional pugilism and, by extension, other combat sports, such as mixed martial arts (MMA) and Muay Thai. (shrink)

ABSTRACT This paper seeks to develop a philosophical framework for what I argue are the Nietzschean and Kantian aspects of professional boxing matches: narrative dissimulation and moral obligation. The overarching objective of the analysis is to shed a critical light on brief intervals of boxing competitions (the minute between rounds) that are crucial but often overlooked in the philosophical literature devoted to boxing and, indeed, combat sport more generally. Additionally, in characterizing more fully the philosophical complexities of cornerman and boxer (...) interactions in the flow of such a violent and dangerous sport, the analysis aims to make explicit some of what is unique—and uniquely problematic—to competing in and coaching professional pugilism and, by extension, other combat sports, such as mixed martial arts (MMA) and Muay Thai. (shrink)

A method of using co-citation data to identify scientific specialties and trace their development through time is outlined. These are related to the structuralist "theory net" construct. The method is purely "theoretical in that no algorithms for implementing the method are suggested. Even at this theoretical level, the discussion is incomplete in several ways. Important formal properties of some of the concepts employed remain to be clarified. The specific way these constructs relate to theory nets remains to be specified in (...) detail. (shrink)