BackgroundMild cognitive impairment is a common neurological disorder. Moxibustion has been shown to be effective in treating MCI, but its therapeutic mechanisms still remain unclear. This study mainly aimed to investigate the modulation effect of moxibustion treatment for patients with MCI by functional magnetic resonance imaging.MethodsA total of 47 patients with MCI and 30 healthy controls participated in resting-state fMRI imaging scans. Patients with MCI were randomly divided into true moxibustion group and sham moxibustion group. The degree centrality approach was (...) applied to distinguish altered brain functions. Correlation analysis was then performed to examine the relationships between the neuroimaging findings and clinical symptoms.ResultsCompared with HCs, patients with MCI mainly showed decreased DC in the left middle frontal cortex and bilateral middle cingulate cortex. After moxibustion treatment, the SHAM group had no significant DC findings, while TRUE group mainly showed significant increased DC in the bilateral MFC and MCC, as well as decreased DC in the left middle occipital cortex. Repeated measures analysis of variance showed significant interactions between the two groups of patients with MCI. In addition, the higher Mini-Mental State Examination score was significantly positively correlated with increased DC in the right MFC and left MCC after moxibustion treatment.ConclusionOur findings demonstrate that the potential value of moxibustion treatment on MCI, which adds new insights into the popular view that moxibustion treatment may slow cognitive decline in patients with MCI. (shrink)

Introduction While quizzing during informed consent for research to ensure understanding has become commonplace, it is unclear whether the quizzing itself is problematic for potential participants. In this study, we address this issue in a multinational HIV prevention research trial enrolling injection drug users in China and Thailand. Methods Enrolment procedures included an informed consent comprehension quiz. An informed consent survey followed. Results 525 participants completed the informed consent survey (Heng County, China=255, Xinjiang, China=229, Chiang Mai, Thailand=41). Mean age was (...) 33 and mean educational level was 8 yrs. While quizzing was felt to be a good way to determine if a person understands the nature of clinical trial participation (97%) and participants did not generally find the quiz to be problematic, minorities of respondents felt pressured (6%); anxious (5%); bored (5%); minded (5%); and did not find the questions easy (13%). In multivariate analysis, lower educational level was associated with not minding the quizzing (6–10 yrs vs 0–5 yrs: OR=0.27, p=0.03; more than 11 yrs vs 0–5 yrs: OR=0.18, p=0.03). There were also site differences (Heng County vs Xinjiang) in feeling anxious (OR=0.07; p=<0.01), not minding (OR=0.26; p=0.03), being bored (OR=0.25; p=0.01) and not finding the questions easy (OR=0.10; p=<0.01). Conclusions Quizzing during the informed consent process can be problematic for a minority of participants. These problems may be associated with the setting in which research takes place and educational level. Further research is needed to develop, test and implement alternative methods of ensuring comprehension of informed consent. Trial Registration clinicaltrials.gov number NCT00270257. (shrink)

在宋儒學脈自二程至黃幹一系師承的啟發下，本書稿連續性地縱觀明儒學脈的師承進路，延著吳溥、楊溥—吳康齋—陳白沙—湛甘泉—唐一庵—許敬庵—劉念台不間斷的時間線索，圍繞明代諸儒的核心範疇與核心概念“至善性體 ”展開，試圖在陽明心學于明朝大瀾、大明與大傳播的框架外，找尋明儒學脈的新線索，發現有明一朝中國學術內在邏輯成長的新視野。.

Stellvertretend für den traditionellen Konfuzianismus wird die Moralphilosophie Zhu Xis näher untersucht, um die darin enthaltenen hermeneutischen Elemente Verstehen und Praxis im Zusammenhang mit den klassischen Schriften herauszuarbeiten. Dabei erweist sich Hans-Georg Gadamers hermeneutisches Denken als hervorragende Vergleichsgrundlage. Das Wahrheitsproblem bei Texten - und folglich auch deren Sinn - kann laut Gadamer nur durch die Geschichtlichkeit des Verstehens und in konkreten Situationen erfaßt werden, und zwar in dem Sinne, daß Verstehen immer Andersverstehen heißt. Bei Zhu Xi wird Andersverstehen als die (...) Grundlage der Praxis anerkannt, jedoch nur im Bereich der Bedeutung; geht es aber um das Wahrheitsproblem, so muß ein Andersverstehen völlig ausgeschlossen werden, das Sinnverhältnis muß also stets unveränderlich bleiben. (shrink)

This essay develops an inferential account of model explanation, based on Mauricio Suárez’s inferential conception of scientific representation and Alisa Bokulich’s counterfactual account of model explanation. It is suggested that the fact that a scientific model can explain is essentially linked to how a modeler uses an established model to make various inferences about the target system on the basis of results derived from the model. The inference practice is understood as a two-step activity, with the first step involving making (...) counterfactual statements about the model itself and the second step involving making hypothetical statements transferring over claims derived from the model onto the target. To illustrate how this two-step activity proceeds, an agent-based simulation model is discussed. (shrink)

本书包括:古朝鲜三国及统一新罗时期、高丽时期、朝鲜王朝(李朝)时期、近代时期四编。.

This paper explores the cooperation mechanisms for the prisoner’s dilemma game, a canonical example for studying cooperation mechanisms, with Bayesian games. By the approach allowing simultaneous moves with the assumption that the players might be self-interested or norm-following, we establish four possible Bayesian game models, all of which are cooperation mechanisms for the prisoner’s dilemma game except for the model in which one of the two players must be self-interested.

本书从现代美育理论研究入手、评论著名美学人物、提出把“完美功利主义”作为中国美学现代传统的想法、并对这种现代传统进行阐述。.

Polger and Shapiro argue that their official recipe, a criterion for judging when the phenomenon of multiple realization exists, renders MR less widespread than its proponents have assumed. I argue that, although Polger and Shapiro’s criterion is a useful contribution, they arrive at their conclusion too hastily. Contrary to Polger and Shapiro, I claim that the phenomenon of multiple realization in the biological world, judged by their criterion, is not as scarce as they suggest. To show this, an updated official (...) recipe, namely a multiple mechanistic realization thesis, integrating Polger and Shapiro’s criterion with a compositional conception of realization, is developed. Then, three examples of varied kinds are examined, showing that cases of MR are not so hard to find in the biological world. (shrink)

90 nian dai, Du Weiming xian sheng de geng duo jing li zai yu kai zhan "wen hua Zhongguo" de lun yu."Wen hua Zhongguo" zhuo mo zui duo de shi ru jia de ren wen jing shen, yi jiu zheng jiang ru jia ru shi de jia zhi qu xiang he fan su ren wen zhu yi hun wei yi tan de yin xiang, tu xian ru jia yi mai xiang cheng de pi pan jing shen.

本书研究了西方科学哲学中的八个主要问题,即:认知意义的判断标准、归纳与验证、科学说明模型及其问题、科学的发展模式、科学划界、科学实在论、科学与价值、社会科学哲学。.

Natural selection is a general process that operates in different populations. To characterise natural selection as a mechanism within the framework of the new mechanistic philosophy, it is required to identify a pertinent phenomenon for which natural selection is responsible. Firstly, every case identified by evolutionary biologists as instances of natural selection must align with this mechanistic characterisation. Secondly, natural selection should genuinely be responsible for the attributed phenomenon. While philosophers often posit producing adaptation as the quintessential phenomenon, Pérez-González and (...) Luque challenge this perspective, contending that not all instances of natural selection are cases where natural selection produces adaptation. This paper further supports Pérez-González and Luque’s objection and demonstrates that natural selection is also not responsible for the increased frequency of traits with a greater expected number of offspring. Furthermore, the paper argues that even if there is a phenomenon that allows for the mechanistic characterisation of natural selection to encompass all instances, it is improbable that natural selection assumes responsibility for it. Consequently, characterising natural selection as a mechanism emerges as an implausible stance. (shrink)

This essay examines the depiction of French ragout in eighteenth-century English literature, arguing that the dish reflects social apprehension regarding ideological, cultural, and military conflicts between England and France. This essay first traces a brief history of ragout, along with an overview of the dish’s cultural connotation and complexity, in eighteenth-century English society. It next delves into the concept of eighteenth-century English Francophobia, demonstrating that this sentiment was a mixture of national pride and anxiety amid England’s identity crisis under the (...) potential French cultural threat. Finally, the essay examines ragout in eighteenth-century English literature and identifies the dish as the target of French pretension and cultural invasion. This research highlights the fact that eighteenth-century English authors’ satirical portrait of ragout underscored xenophobic gastronomy and cautioned against a simple interpretation of the dish. The caricature and representation of ragout as a feminized, artificial, and laughable dish reinforces eighteenth-century English writers’ concern for the invasion of foreign culture by emphasizing the contrast between authentic ‛Anglo’ meat consumption and ‛Franco’ sophistication. (shrink)

Emotions are now considered critical elements of a successful education. In English as a Foreign Language context, there are many challenges for teachers to deal with. Hence, it is necessary to take their emotions into consideration. Despite many studies in this area, researching teachers’ positive mood, hope, and academic buoyancy has been left less attended. Trying to introduce this line, the present study reviewed the definitions, related concepts, theories, and previous studies done on these three variables in detail. It also (...) touched upon the origins of researching emotion in educational contexts describing different schools of psychology. Additionally, the study offered some practical implications for EFL teachers, students, policy-makers, teacher trainers, and researchers. Finally, it enumerated the existing gaps in this area and made a number of research suggestions for future research. (shrink)

Michael Weisberg’s account of scientific models concentrates on the ways in which models are similar to their targets. He intends not merely to explain what similarity consists in, but also to capture similarity judgments made by scientists. In order to scrutinize whether his account fulfills this goal, I outline one common way in which scientists judge whether a model is similar enough to its target, namely maximum likelihood estimation method. Then I consider whether Weisberg’s account could capture the judgments involved (...) in this practice. I argue that his account fails for three reasons. First, his account is simply too abstract to capture what is going on in MLE. Second, it implies an atomistic conception of similarity, while MLE operates in a holistic manner. Third, Weisberg’s atomistic conception of similarity can be traced back to a problematic set-theoretic approach to the structure of models. Finally, I tentatively suggest how these problems might be solved by a holistic approach in which models and targets are compared in a non-set-theoretic fashion. (shrink)

本书主要是针对我国当前改革建设的实践,运用马克思主义的哲学原理,加以深入的论述,特别是关于改革与社会心理、人的本质和人的价值、思维方式的变革、宗教等问题的论述、有新意、有深度。.

Since 2004, Nanyan Cao and some other scholars have implicitly or explicitly claimed that engineering ethics in China is importantly different from engineering ethics in the United States. The evidence for that claim relies on examination of official documents or certain large features of Chinese society. Though neither is an uncommon approach to studying engineering ethics in China, neither actually studies engineering practice in China. This article does—or at least gets much closer. The authors have asked almost two hundred Chinese (...) engineers about what they do and why they do it. The responses suggest that Chinese engineers, or at least those surveyed, think about engineering ethics much as American engineers do. The responses also suggest that much more empirical work needs to be done before we can claim to understand either the similarities or differences between engineering ethics in China and engineering ethics in “the West.”. (shrink)

In this paper, we propose an empirically based Monte Carlo bus-network model as a test bed to simulate intervention strategies to overcome the inefficiencies of bus bunching. The EMB model is an agent-based model which utilizes the positional and temporal data of the buses obtained from the Global Positioning System to constitute a set of empirical velocity distributions of the buses and a set of exponential distributions of interarrival time of passengers at the bus stops. Monte Carlo sampling is then (...) performed on these two derived probability distributions to yield the stochastic dynamics of both the buses’ motion and passengers’ arrival. Our EMB model is generic and can be applied to any real-world bus network system. In particular, we have validated the model against the Nanyang Technological University’s Shuttle Bus System by demonstrating its accuracy in capturing the bunching dynamics of the shuttle buses. Furthermore, we have analyzed the efficacy of three intervention strategies: holding, no-boarding, and centralized-pulsing, against bus bunching by incorporating the rule set of these strategies into the model. Under the scenario where the buses have the same velocity, we found that all three strategies improve both the waiting and travelling times of the commuters. However, when the buses have different velocities, only the centralized-pulsing scheme consistently outperforms the control scenario where the buses periodically bunch together. (shrink)

Tu (Chinese history and philosophy, Harvard U.) offers a panoramic view of the core values of Confucian intellectual thought that have kept it vital for more than two millennia, and underlie the recent resurgence in eastern Asia. Of interest to students of either China or religion and ethics. Paper edition (unseen), $14.95. Annotation copyright by Book News, Inc., Portland, OR.

Emotion recognition is an important part of building an intelligent human-computer interaction system and plays an important role in human-computer interaction. Often, people express their feelings through a variety of symbols, such as words and facial expressions. A business ecosystem is an economic community based on interacting organizations and individuals. Over time, they develop their capabilities and roles together and tend to develop themselves in the direction of one or more central enterprises. This paper aims to study a multimodal ER (...) method based on attention mechanism. It analyzes the current emotional state of consumers and the development direction of enterprises through multi-modal ER of human emotions and analysis of market trends, so as to provide the most appropriate response or plan. This paper firstly describes the related methods of multimodal ER and deep learning in detail, and briefly outlines the meaning of enterprise strategy in the business ecosystem. Then, two datasets, CMU-MOSI and CMU-MOSEI, are selected to design the scheme for multimodal ER based on self-attention mechanism. Through the comparative analysis of the accuracy of single-modal and multi-modal ER, the self-attention mechanism is applied in the experiment. The experimental results show that the average recognition accuracy of happy under multimodal ER reaches 91.5%. (shrink)

Why Lazarus Laughed explicates the essential doctrine shared by the traditions of Zen Buddhism, Advaita, and Tantra. Wei Wu Wei has become an underground spiritual favorite whose fans anxiously await each reissued book.

I propose a dynamic causal approach to characterizing the notion of a mechanism. Levy and Bechtel, among others, have pointed out several critical limitations of the new mechanical philosophy, and pointed in a new direction to extend this philosophy. Nevertheless, they have not fully fleshed out what that extended philosophy would look like. Based on a closer look at neuroscientific practice, I propose that a mechanism is a dynamic causal system that involves various components interacting, typically nonlinearly, with one another (...) to produce a phenomenon of interest. (shrink)

The spread of epidemics, especially COVID-19, is having a significant impact on the world. If an epidemic is not properly controlled at the beginning, it is likely to spread rapidly and widely through the coexistence relationship between natural and social systems. A university community is a special, micro-self-organized social system that is densely populated. However, university authorities in such an environment seem to be less cautious in the defence of an epidemic. Currently, there is almost no quantitative research on epidemic (...) spreading and response strategies in universities. In this paper, a case study of a university community is considered for a simulation of an infection evolving after an epidemic outbreak based on the method of system dynamics of the three stages. The results show the following: By improving the speed of the initial emergency response, the total number of patients can be effectively controlled. A quarantine policy helps to slow down the evolution of infection. The higher the isolation ratio, the higher the cost; therefore, the isolation ratio should be optimized. It is important to make emergency plans for controlling epidemic spreading and carry out emergency drills and assessments regularly. According to the results of this study, we suggest an emergency management framework for public health events in university communities. (shrink)

In this essay I propose that what design principles in systems biology and systems neuroscience do is to present abstract characterizations of mechanisms, and thereby facilitate mechanistic explanation. To show this, one design principle in systems neuroscience, i.e., the multilayer perceptron, is examined. However, Braillard contends that design principles provide a sort of non-mechanistic explanation due to two related reasons: they are very general and describe non-causal dependence relationships. In response to this, I argue that, on the one hand, all (...) mechanisms are more or less general, and on the other, many design principles are causal systems. (shrink)

本书分“德治论坛”、“全球化与伦理问题论坛”、“青少年道德教育论坛”三部分,收录了“儒家伦理与道德义务的权利性条件”、“生命伦理学的前沿问题”、“荀子的生态伦理思想”、“科技时代性伦理问题的向度”等文 章。.

Vādanyāya is one of the representative works of Dharmakīrti. It is concerned with debate logic and deals with win-or-lose reasoning rules in the broad sense of logic. In this paper, we will concentrate our discussion on Dharmakīrti’s theory of nigrahasthāna (fault) in his debate logic, a key issue in Vādanyāya. First, we point out that the justification of three logical reasons as proof conditions of debate constitutes the rational point of departure for Dharmakīrti’s debate logic. Second, we analyze the differences (...) between Dharmakīrti’s and the Naiyāyika’s notion of debate and point out that Dharmakīrti’s ‘debate’ involves two parties (the disputant and the opponent) attempting to rationally refute the other’s opinion to persuade the other to change their wrong ideas. Last, based on the discussion of Dharmakīrti’s concept of debate logic, we identify seven types of nigrahasthāna in Vādanyāya with regard to the two parties of a debate (the disputant and the opponent). (shrink)

分: 哲学与时代精神、现代自然科学与辩证唯物主义、马克思主义哲学与宗教等9个专题。.

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 41.1 (2003) 123-124 [Access article in PDF] Andrew Barker. Scientific Method in Ptolemy's Harmonics. New York: Cambridge University Press, 2001. Pp. viii + 281. Cloth, $69.95. Ptolemy's Harmonics is an important source not only for the history of music, but also for the history and philosophy of science. Two recent monographs, by J. Solomon, and A. Barker, now provide a basis for a (...) more widespread discussion of this much neglected work. Barker focuses on the part that is concerned with musical science proper (I, 1-III, 3), and more specifically on the scientific method it displays.Barker uses an analysis of Ptolemy's programmatic statements in I, 1/2, as a key to a reading of Ptolemy's treatise. His exposition has the format of a commentary, with special emphasis on the methodologically relevant passages. For the most part, he follows the order of Ptolemy's text closely, providing historical background information in excursus form. One needs to read a complete text of Ptolemy's treatise along with Barker's exposition in order to understand some of his arguments. It is preferable to also use Düring's [End Page 123] edition of the Greek text. One is rewarded with a detailed and in-depth analysis of the passages that helps one understand Ptolemy's method in harmonics as it unfolds in his treatise. This is so even if one disagrees with Barker's claims concerning Ptolemy's methodology.These claims are outlined in chapter 2, on the basis of I, 1/2 of the Harmonics. The methodological program Barker filters out of the text remains vague in a number of important respects. One misses, for example, a clear exposition on what will count as a sufficient integration of "empirical and theoretical phases," and on what will count as "empirical." This is a serious drawback, since Barker claims that Ptolemy instantiates a complex scientific methodology with a decisive, fully integrated empiricist trait. The drawback is aggravated by the fact that the already vague terms of the postulated methodology have to be watered down considerably in the subsequent chapters to make them fit with Ptolemy's actual procedures. Ptolemy does not seem to deliver even on the vague terms. One may very well remain unconvinced both by Barker's initial arguments concerning Ptolemy's methodology, and by his attempts to show that Ptolemy's procedure in the Harmonics can count as a satisfactory instantiation. Perhaps Ptolemy's intentions are less ambitious. When he states (5.13 ff. Düring, ed.) that "the aim of the student of harmonics must be to preserve the hupotheseis..., as never in any way conflicting with the perceptions that correspond to most people's estimation," he may just mean that he intends to vindicate an essentially Pythagorean (locally modified) account by showing it does not conflict with the phenomena. In my view, he certainly delivers on this less ambitious program. In fact, it seems to me that the understanding of Ptolemy's argumentative path is impeded by Barker's interpretation of Ptolemy's goal of "saving the hupotheseis" as a commitment to the integration of a genuine empiricist trait.Chapters 7 and 8 give an exposition of Ptolemy's tetrachord divisions. For the reader interested in an evaluation of the theoretical aspect of Ptolemy's scientific method, these are the central chapters of Barker's book. Barker provides a detailed analysis, together with an exposition of the historical and technical information needed for a non-specialist to follow both his and Ptolemy's argument. Barker's analysis reveals inter alia that a considerable part of Ptolemy's theory has no counterpart in the realm of phenomena perceived as musical, and that another part, concerning the single most important division of musical practice, is not justified, and not justifiable, by derivation from the principles. It is difficult to see how Ptolemy's account can nevertheless be viewed as a genuine integration of empirical and theoretical aspects. It appears to be an attempt at showing that an essentially Pythagorean theory... (shrink)