At the beginning of Book 5 Plato catalogues the ways in which men ‘dishonour’ their souls, and at 728 ab sums up by saying that any man who does not practise what the lawgiver describes as noble and good is treating his soul dishonourably. He goes on to say that hardly anyone takes account of, which is to cut oneself off from good men and be completely assimilated to the bad. We the n read.

At the beginning of Book 5 Plato catalogues the ways in which men ‘dishonour’ ([Greek text] 727 c 3) their souls, and at 728 ab sums up by saying that any man who does not practise what the lawgiver describes as noble and good is treating his soul dishonourably. He goes on to say that hardly anyone takes account of [Greek text] (728 b 2), which is to cut oneself off from good men and be completely assimilated to the (...) bad [Greek text]. We the n read. (shrink)

At the beginning of Book 5 Plato catalogues the ways in which men ‘dishonour’ their souls, and at 728 ab sums up by saying that any man who does not practise what the lawgiver describes as noble and good is treating his soul dishonourably. He goes on to say that hardly anyone takes account of, which is to cut oneself off from good men and be completely assimilated to the bad. We the n read.

It is shown that the Kapitza-Dirac effect with atoms, which has been considered to be evidence for their wavelike character, can be interpreted as a scattering of pointlike objects by the periodic laser field.

In Ennead 3.6, Plotinus maintains that the soul is unaffectable. This thesis is widely taken to imply that his soul is exempt from change and free from emotional ‘affections’. Yet these claims are difficult to reconcile with evidence that Plotinian souls acquire dispositional states, such as virtues, and are subjects of emotional ‘affections’, such as anger. This paper offers an alternative account that aims to address these difficulties. In denying affections to soul, Plotinus is offering a distinction between the soul’s (...) self-actuated motions (or "activities") and the passive motions (or "affections") of bodies. But this distinction does not imply the soul’s changelessness, since Plotinus regards psychic motions that culminate in the soul’s acquisition of new dispositional states as changes. As for emotional ‘affections’, these (as activities) are merely homonymous with the affections denied to soul, and so do not violate the ban on the soul’s affectability. (shrink)

In this paper, I investigate the foundations of Plotinus’ innovative theory that prime matter is unaffectable. I begin by showing that Plotinus’ main arguments for this thesis (in Ennead 3.6) all rely upon the controversial assumption that the properties prime matter underlies are not properties of prime matter itself. It is then argued that prime matter’s privation of sensible qualities has its conceptual basis in an idiosyncratic understanding of form-matter composition generally, and its primary doctrinal basis in Aristotle’s critical reports (...) on the Platonists’ substratum in Physics 1.9. While Plotinus finds Platonic authority for unaffectible matter in the Receptacle passage of the Timaeus, it is Aristotle’s testimony that provides the crucial impetus for reading that text in this way. On this basis, Plotinus develops a Platonist conception of form’s inherence in matter with distinctively non-Aristotelian features. (shrink)

The recent production of major treatises devoted to elaborating normative ethical theories and the eruption of lively debates concerning the merits of opposed normative systems have been greeted with applause. This reaction is an historical about-face, since for forty or fifty years “ethical” treatises had been attacking the pretensions of traditional moral philosophy, calling for its demise or at the least severely limiting its claims. These skeptical attacks had succeeded in seriously undermining the academic status of moral philosophy and consequently (...) moral philosophy was transformed into “metaethics,” a highly abstract and technical discipline considered much less necessary to the general education of students than what it replaced and with a diminished role in the curriculum. The recent resurgence of interest in normative ethics has generally been lauded as a sign that philosophy has rededicated itself to its proper and time-honored tasks. There is a widespread feeling that the overblown claims of twentieth century skepticism have been whittled down to innocuous proportions and thus that nothing stands in the way of proceeding to construct ethical theories. The study of normative ethical theory now enjoys such respectability and popularity that it is difficult to raise once more the uncomfortable ideas that the ideal of normative ethical theory is a false one, that vanquishing the spectre of noncognitivism is not sufficient for legitimizing it, and that the popular new justifications for the enterprise fail in mischievous ways. (shrink)

Mathematical models of the heart have developed over a period of about 40 years. Cell types in all regions of the heart have been modelled and they are now being incorporated into anatomically detailed models of the whole organ. This combination is leading to the creation of the first ‘virtual organ,’ which is being used in drug discovery and testing, and in simulating the action of devices, such as cardiac defibrillators. Simulation is a necessary tool of analysis in attempting to (...) understand biological complexity. We often learn as much from the failures as from the successes of mathematical models. It is the iterative interaction between experiment and simulation that is important. Examples are given where this process has been instrumental in some of the major advances in the field. BioEssays 24:1155–1163, 2002. © 2002 Wiley‐Periodicals, Inc. (shrink)

Whatever its grammatical status, the verb “to discern” has an implicit transitive element. That is to say, we always discern about something or between two options. What is the right course of action in this situation and in these circumstances? In our paper, we want to look at responses to this question from the perspective of the theology of liberation. As the name implies, this is first and foremost a theology, a way of seeking to understand and articulate the faith (...) of the believing Christian community. But it is also necessarily political, because it seeks to contribute to the liberation of those who are not free – the poor, the oppressed, those to whom injustice is done, both negatively, by decrying the presence of unfreedom and positively by working for social transformation. It is thus a public theology, a manifestation of the ongoing power of religion to inform and motivate its adherents to engage in attempts to transform the world not only in terms of a post mortem future but here and now. (shrink)

This paper analyzes Leibniz’s use of analogies in both natural philosophical and metaphysical contexts. Through an examination of Leibniz’s notes on scientific methodology, I show that Leibniz explicitly recognizes the utility of analogies as heuristic tools that aid us in conceiving unfamiliar theoretical domains. I further argue that Leibniz uses the notion of a self-moving machine or automaton to help capture the activities of the immaterial soul. My account helps resist the conventional image of Leibniz as an arch-rationalist unconcerned with (...) methods of empirical discovery and contributes to ongoing discussions on the nature of immaterial substance and mind in Leibniz. (shrink)

Three major trends in American health policy are intersecting in a fascinating way. First, managed care has grown to become the most dominant form of health-care delivery, leading to reductions in health-care costs as insurers are able to influence health-care providers with financial incentives. Second, the present growth of managed care has slowed, almost to a standstill, largely on account of consumers questioning what effects these financial incentives are having on the care of patients — questioning that has been expressed (...) in particular through lawsuits against managed care companies.Third, we are experiencing a renewed interest in the existence of medical error and how it may be reduced as a result of the Institute of Medicine’s report, To Err Is Human: Building a Safer Health System. The most important aspect of this renaissance in error reduction has been its emphasis on health care as a system that can be made better through system-oriented change. The most frustrating aspect is that the IOM did not endorse change in malpractice liability, which consistently puts the impetus for reducing medical error on the individual provider rather than the system as a whole. (shrink)

Three major trends in American health policy are intersecting in a fascinating way. First, managed care has grown to become the most dominant form of health-care delivery, leading to reductions in health-care costs as insurers are able to influence health-care providers with financial incentives. Second, the present growth of managed care has slowed, almost to a standstill, largely on account of consumers questioning what effects these financial incentives are having on the care of patients — questioning that has been expressed (...) in particular through lawsuits against managed care companies.Third, we are experiencing a renewed interest in the existence of medical error and how it may be reduced as a result of the Institute of Medicine’s report, To Err Is Human: Building a Safer Health System. The most important aspect of this renaissance in error reduction has been its emphasis on health care as a system that can be made better through system-oriented change. The most frustrating aspect is that the IOM did not endorse change in malpractice liability, which consistently puts the impetus for reducing medical error on the individual provider rather than the system as a whole. (shrink)

The Weismann Barrier and the Central Dogma do not protect the assumptions of The Modern Synthesis.

This article examines the utopian vision present in the eponymous work by Thomas More and in the early Anabaptists. In the light of the discussion on the power and dangers of utopian thinking in liberation theology it seeks to show how More struggled with the tension between the positive possibilities of a different world and the destructive criticism of the present reality. A similar tension is found in early Anabaptist practices, especially in terms of their relationship to the state and (...) their practice of commonality of goods. The article shows that that all attempts to reduce visions of a better world to a particular setting end up as ideological. (shrink)

Numerous mediators are involved in both the control and the transmission of nociceptive messages, and several lines of research have been developed in the management of pain. Complete enkephalin- degrading enzyme inhibitors, which produce naloxone-reversible analgesia in all tests where morphine has been found to be active, remains the most promising way. CCK compounds, especially the CCKB antagonists also may be interesting drugs. Indeed, they are able to strongly potentiate the antinociceptive effects of the opioids. [dickenson, wiesenfeld-hallin et al.].

In this paper, I discuss how Plotinus seeks to reconcile (1) the transcendence of providential thought with its creation of an optimal cosmos, (2) providence's comprehensive oversight with the existence of evils, and (3) fate with human autonomy and moral responsibility.

Despite the unprecedented freedoms that decolonization has brought for many Black1 people – especially in specific regions of the African Diaspora – freedom and its fulfilment, adequate signs and contested meanings remain a preoccupation within Black cultural discourses and practices. At the same time, while political and cultural nationalisms have led to greater political and civil rights, racism has not been eradicated. Furthermore, the new postcolonial globalizations of capital, people and cultures have destabilized the collective identities that framed twentieth-century struggles (...) for national sovereignty and equal citizenship, without necessarily erasing them. Instead, they remain, no longer securely anchored in their old homogenous appearances, but re-configured through the inner differences and contradictions of gender, sexuality, ethnicity and religion. This article addresses these internal differences and the ways in which they produce new contestations over race, the meaning of Black representation and postcolonial freedom, negotiations that are increasingly traced on the intimate contours of the body and the self, through practices of personal consumption, erotic hedonism and style as key performances of freedom. It achieves this through examining two localized moments in the transnational and diasporic circulation of Jamaican dancehall culture, understood as a privileged public space for the performance of Black identifications and personal freedom. It argues that the eroticized discourses of ethnicity, race and gender found in dancehall culture articulate the dominance of neo-liberal conceptions of freedom at the same time as they express, resist and comment on new cultural hegemonies not reducible to racism or the power of the West; that is how dancehall expresses the new problematizations of postcoloniality. 1Except when quoting other writers, I will capitalise the word Black, in order to recognise Black identity as a historically and politically constituted experience and representational category, and not solely denoting skin colour. (shrink)