Molecular chaperones assist de novo protein folding and facilitate the refolding of stress‐denatured proteins. The molecular chaperone concept was coined nearly 35 years ago, and since then, tremendous strides have been made in understanding how these factors support protein folding. Here, we focus on how various chaperone proteins were first identified to play roles in protein folding. Examples are used to illustrate traditional routes of chaperone discovery and point out their advantages and limitations. Recent advances, including the development of folding (...) biosensors and promising methods for the stabilization of proteins in vivo, provide new routes for chaperone discovery. (shrink)

本书分为前言、慎言全译、雅述全译、慎言原文、雅述原文、索引六部分,主要内容包括:王廷相生平、王廷相的哲学思想、王廷相的社会政治思想、当时及后世对王廷相的评价等.

本书分“德治论坛”、“全球化与伦理问题论坛”、“青少年道德教育论坛”三部分,收录了“儒家伦理与道德义务的权利性条件”、“生命伦理学的前沿问题”、“荀子的生态伦理思想”、“科技时代性伦理问题的向度”等文 章。.

本书包括“全球化”语境下的哲学反思、经济哲学研究与我国社会主义建设、文化多样性与中国特色社会主义文化建设、当代哲学与政治研究、“网络时代”的科技与人、“三个代表”理论的哲学思考、马克思主义哲学教学与改 革等若干方面。.

全书共收旧题鬼谷子撰的著作22篇,汇集了现存所有鬼谷子著述及托名鬼谷子的著述。并附录了各种珍本及秘本和历代学者对鬼谷子及其著述的记录和评价。.

본고는 동아시아의 문화권에서 유가의 사상이 어떻게 국가공동체의 통치이념으로 자리잡았을 수 있었는가 하는 문제의식에서 출발한다. 그것은 漢代에 동중서가 유가의 王道를 채택하여 국가의 체제를 확립하는 이념화의 과정과 맞물려있다. 그는 公羊學의 비판정신에 입각하여 大一統의 공동체의식을 확립하고 天下經綸의 경계를 확보하고자 하였다. 이러한 지향성에는 삼중의 노선, 즉 學統, 道統및 政統의 입체적 노선이 있다. 즉 學統의 이론적 체계에 따라 道統의 대원칙을 계승하고 政統의 정당성을 확보하려는 것이다. 이들의 입체적 노선은 道義의 명분에 따라 正義의 실현을 모색하는 通權達變의 治世觀에서 설명된다. 이러한 치세관은 한왕조의 정통성과 그에 따른 통치의 정당성을 확보하기 (...) 위한 초석을 다졌다. 그것은 당위적 도덕성과 합리적 현실성 사이에 긴장관계를 지속적으로 유발시키는 정치철학의 문제로 표출되었다. 이는 王道와 覇道의 모순이나 충돌과 같은 정치철학의 문제를 노출시켰다. 예를 들어, 한왕조가 개창되고 왕조의 교체라는 대의명분을 확보하기 위해 新王의 합법성이 필요하였다. 동중서는 주나라의 왕실을 존중하는 존왕의 명분을 한왕조를 개창한 新王의 실리로 전환하였다. 즉 尊王의 春秋學的명분을 넘어 新王의 公羊學的 명분을 내세웠다. 존왕에서 신왕으로의 변용은 통치권력의 의지가 이동하는 특징을 시사적으로 드러내고 있다. 여기에는 王道와 覇道사이에 서로 양분할 수 없는 관계, 즉 상생과 상극의 미묘한 관계가 성립한다. 여기에는 왕도와 패도의 미묘한 긴장관계, 즉 패도의 부당성을 왕도의 정당성으로 변용하는 逆說的측면도 있다. 이러한 通權達變의 治世觀은 결국에 정치의 윤리화 혹은 윤리의 정치화를 낳는 결과를 초래하였다. 여기에는 역사적 교훈의 필연성과 시대적 요청의 절박성이라는 양단의 칼날(dilemma)을 충족시키기 위한 천하경륜의 지속가능한 경계가 반영되어 있다. (shrink)

v.1 Shu ji zhuan ; Zhong yong ji lüe -- v.2 Cheng shi yi shu ; Cheng shi wai shu -- v.3 Shang cai yu lu ; Wei zhai ji -- v.4 Nan Xuan xian sheng wen ji.

本次出版的《槐轩全书》乃以刘沅之孙、“天才学者”刘咸炘先生亲校之西充鲜于氏特园藏本为底本整理修复而成.

本书从科学诠释学的提出,科学诠释学的学术传统、科学诠释学的基本特征以及科学诠释学的研究状况等方面对科学诠释学作了分析和阐述。.

v. 1. Lun li xue yuan li juan -- v. 2. Zhongguo lun li si xiang shi juan -- v. 3. Makesi zhu yi lun li si xiang shi juan -- v. 4. Dong fang lun li si xiang shi juan -- v. 5. Xi fang lun li si xiang shi juan -- v. 6. Xian dai xi fang lun li xue juan -- v. 7. Zhi ye lun li xue juan -- v. 8 Ying yong lun li xue juan (...) -- v. 9. Hun yin jia ting lun li xue juan -- v. 10. De yu lun li xue juan -- v. 11. Zong jiao lun li xue juan. (shrink)

本书从唐朝一桩谋杀案讲起,通过大量生动的历史案例,运用翔实考据和缜密逻辑,揭示了上溯至春秋时代的中国经典文化,包括春秋"一经三传",论语老子等,是如何在皇权政治下被扭曲成了权力的工具的.

本书内容包括:中国古代生态美学思想寻踪、西方文化生态资源撷英、民族文化生态美窥视、生态美的学理研讨、生态美的实证研究。.

As humans, we use the power of thinking to make scientific discoveries, develop technologies, manage social interactions, and transmit knowledge to the next generations. With the ability to think, we can trace back and discover the origin of the universe, the natural world, and ourselves. The content of this book, Mindsponge Theory, is part of that discovery process. -/- Product Details -/- Publisher ‏ : ‎ Walter de Gruyter (December 6, 2022) Publication date ‏ : ‎ December 6, 2022 Language (...) ‏ : ‎ English Hardcover ‏ : ‎ 214 pages ISBN-10 ‏ : ‎ 8367405145 ISBN-13 ‏ : ‎ 978-8367405140 Dimensions ‏ : ‎ 6.3 x 0.71 x 9.29 inches -/- . (shrink)

volume 1. Yi tong ; Zhou yi jiang zuo -- volume 2. Zhou yi quan jie -- volume 3. "Zhou yi, Xi ci zhuan" xin bian xiang jie ; "Shang shu, Yu xia shu" xin jie -- volume 4. Zhongguo nu li she hui de ji ge wen ti ; Lun jing tian zhi du ; Zhongguo nu li she hui shi -- volume 5. Kongzi xin zhuan -- volume 6. Jing xue gai lun ; Xian Qin si xiang (...) shi ; Xian Qin si xiang shi zhuan ti jiang shou ti gang -- volume 7. Lun wen Jing xue bian, Shi xue bian -- volume 8. Lun wen Shi xue bian, Zi xue bian -- volume 9. Lun wen Zi xue bian, Xu ba bian, Za zhu bian ; Zi zhuan -- volume 10. Fu lu. (shrink)

When you type the word “serendipity” in a word-processor application such as Microsoft Word, the autocorrection engine suggests you choose other words like “luck” or “fate”. This correcting act turns out to be incorrect. However, it points to the reality that serendipity is not a familiar English word and can be misunderstood easily. Serendipity is a very much scientific concept as it has been found useful in numerous scientific discoveries, pharmaceutical innovations, and numerous humankind’s technical and technological advances. Therefore, there (...) have been many books written around the concept. So why do we need this additional book? This is not just another book about serendipity. It has evolved from the Editor’s question lingering for a decade after finishing his widely cited article (coauthored with Prof. Nancy K. Napier of Boise State University, ID, USA) “Serendipity as a strategic advantage?” in T. Wilkinson’s edited volume Strategic Management in the 21st Century, published by Praeger. The Editor and contributing authors have tried to achieve the following in this title. Demystifying the Serendipity Myth The phenomenon of serendipity has always been thought of as a “miracle”. It is the mystery of human innovation and one of the ultimate secrets of our society. But serendipity is not just a lucky coincidence nor any hidden conspiracy. This book explores the science of the information process behind this seemingly miraculous phenomenon. It connects human society with nature, going back to the root of our existence and looking at the flame of survival to discover the harmony in making creativity. Presenting the nuts and bolts of being an adventurer of science The authors present their conceptual investigations into serendipity’s nature and its mechanism by examining interesting real events and stories. The content is thought-provoking, and readers are led to question and explore their own life stories and problems along the journey of reading this book. Catching an elusive high-value target requires great strategies and efforts. But there are no dark secrets here because this is the “way of nature” – how we humans have always strived for innovation without realizing the blueprints behind such processes. Unlike other books on serendipity, this book will show you that a powerful “secret” is closer than you think. Delivering practical uses for different audiences By understanding the conditionality and survival drivers of serendipity, individuals or organizations can make better decisions on creating the right environment to facilitate the encounter and attainment of this valuable phenomenon. For scientists: With clear explanations of the information processes underlying serendipity, flexible theoretical frameworks of mindsponge and the 3D principle of creativity, researchers are provided with the tools they need to dig deeper into their own fields of study and find practical applications, be it psychology, economics, sociology, or anything that involves innovation (which is, in fact, every scientific discipline). For curious casual readers: Everybody needs innovation to make breakthroughs or spice up one’s life. If you think great ideas come to people randomly from an unknown fairy place, this book will convince you otherwise without taking away that awe and wonder. But above all, you will know how to become more creative, scientifically and straightforwardly, with no snake oil and no weird tricks. For ambitious business people: The flame that brought about great successes throughout human history is within you. But you can only use it if you understand it. While others wait for serendipity to come, you will be able to actively hunt for those precious moments. As it has always been: the best hunters triumph, not the passive wanderers. And in this age of information chaos, finding the golden fruits is not easy. Those from information technology know this problem well, and this book is the treasure map that they have been seeking to navigate that stormy ocean looking for jewels. Like a kingfisher tracking its prey through the water, waiting to gracefully strike, with serendipity, a person seizes the prize of creativity amid the chaos of life. ¤ ¤ ¤ Official introduction: The book explores the nature, underlying causes, and the information processing mechanism of serendipity. It proposes that natural or social survival demands drive serendipity, and serendipity is conditional on the environment and the mindset, on both individual and collective levels. From Darwin's evolution theory to Sun Tzu's war tactics, major innovations throughout human history are unified by this key concept. In the rapidly changing world, information is abundant but rather chaotic. The adaptive power of serendipity allows people to notice treasures within this wild sea, but only for those who understand how it works. To increase the probability of encountering and attaining serendipity, one should employ the mindsponge mechanism and the 3D process of creativity, for without these frameworks, serendipity is truly an elusive target. The book also discusses methods to build environments and cultures rich in navigational and useful information to maximize the chance of finding and capitalizing on serendipity. As a skill, serendipity has a resemblance to how kingfishers observe and hunt their prey. (shrink)

1. Huai hai yi tan ; Si shu jin yu -- 2. Zuo cui ti ping -- 3. Zhuang yi yao shan -- 4. Sun Shanfu du xue wen ji ; Xue kong jing she shi gao ; Lun xia xi guan shi zhu sheng xi wen ; You xin yao cao ; Ji yi ; Sun Ying'ao bei ke ji yi.

Ben shu xi tong chan shu liao Zhongguo zhe xue de yuan qi, fa zhan he wei lai.quan shu gong fen cheng si ge da bu fen:yuan qi yu chu xing; er, ge ming hua de ding xing; san, xin shi dai de zhuan xiang;si, zou xiang quan qiu hua shi dai de Zhongguo zhe xue.

The book examines the psycho-religious mechanism behind the violent extremism of suicide attacks in the post-9/11 world. It employs the mindsponge concept, an original dataset, and original research results obtained from the authors' statistical investigations using the Hamiltonian Markov chain Monte Carlo technique. It provides insights and implications for policymakers and strategists in their efforts to engage in peace talks and reduce violent conflicts worldwide.

“Throw away anything that sounds too complicated. Only keep what is simple to grasp...If the information appears fuzzy and causes the brain to implode after two sentences, toss it away and stop listening. Doing so will make the news as orderly and simple to understand as the truth.” - In “GHG emissions,” The Kingfisher Story Collection, (Vuong 2022a).