Despite the recent discovery that thalidomide causes limb defects by targeting highly angiogenic, immature blood vessels, several challenges still remain and new ones have arisen. These include understanding the drug's species specificity, determining molecular target(s) in the endothelial cell, shedding light on the molecular basis of phocomelia and producing a form of the drug that is clinically effective without having side effects. Now that the trigger of thalidomide‐induced teratogenesis has been uncovered, a framework is proposed, incorporating and uniting previous models (...) of thalidomide action, explaining how thalidomide causes not just limb defects, but also all the other defects it induces. (shrink)

What is morality? In Practical Expressivism, I argue that morality is a purely natural interpersonal co-ordination device, whereby human beings express their attitudes in order to influence the attitudes and actions of others. -/- The ultimate goal of these expressions is to find acceptable ways of living together. This 'expressivist' model for understanding morality faces well-known challenges concerning 'saving the appearances' of morality, because morality presents itself to us as a practice of objective discovery, not pure expression. -/- This book (...) demonstrates how a properly developed expressivist view can overcome this objection, by showing that even if moral practice is fundamentally expressive, it can still come to possess those features that make it appear objective (features such as talk and thought of moral disagreement, truth and belief, and the applicability of logical notions to moral sentences). The key to this development is to emphasise the unique and intricate practical role that morality plays in our lives. Practical expressivism is also practical in the further sense that it provides repeatable patterns that expressivists can deploy in coming to understand the apparently objective features of morality. (shrink)

This chapter considers the nature of imagination and belief, exploring how deeply these two states of mind differ. It first addresses a range of cognitive and motivational differences between imagination and belief which suggest that they're fundamentally different states of mind. Then it addresses imaginative immersion, delusions, and the different norms we apply to the two mental states, which some theorists regard as providing support for a more unified picture of imagination and belief.

This paper applies the theory of teleosemantics to the issue of moral content. Two versions of teleosemantics are distinguished: input-based and output-based. It is argued that applying either to the case of moral judgements generates the conclusion that such judgements have both descriptive (belief-like) and directive (desire-like) content, intimately entwined. This conclusion directly validates neither descriptivism nor expressivism, but the application of teleosemantics to moral content does leave the descriptivist with explanatory challenges which the expressivist does not face. Since teleosemantics (...) ties content to function, the paper also offers an account of the evolutionary function of moral judgements. (shrink)

Many philosophers argue that the face-value of moral practice provides presumptive support to moral realism. This paper analyses such arguments into three steps. (1) Moral practice has a certain face-value, (2) only realism can vindicate this face value, and (3) the face-value needs vindicating. Two potential problems with such arguments are discussed. The first is taking the relevant face-value to involve explicitly realist commitments; the second is underestimating the power of non-realist strategies to vindicate that face-value. Case studies of each (...) of these errors are presented, drawn from the writings of Shafer-Landau, Brink and McNaughton, and from recent work in experimental metaethics. The paper then considers weak presumptive arguments, according to which both realist and non-realist vindications of moral practice are possible, but the realist vindications are more natural. It is argued that there is no sense of ‘natural’ available that can make these arguments work. The conclusion is that all extant presumptive arguments for moral realism fail. (shrink)

This paper advances three necessary conditions on a successful account of sentential negation. First, the ability to explain the constancy of sentential meaning across negated and unnegated contexts (the Fregean Condition). Second, the ability to explain why sentences and their negations are inconsistent, and inconsistent in virtue of the meaning of negation (the Semantic Condition). Third, the ability of the account to generalize regardless of the topic of the negated sentence (the Generality Condition). The paper discusses three accounts of negation (...) available to moral expressivists. The first—the dominant commitment account—fails to meet the Fregean Condition. The two remaining accounts—commitment semantics and the expression account—satisfy all three conditions. A recent argument that the dominant commitment account is the only option available to expressivists is considered and rejected. (shrink)

Recent discoveries in physics, cosmology and biochemistry have captured the public imagination and made the Design Argument - the theory that God created the world according to a specific plan - the object of renewed scientific and philosophical interest. This accessible but serious introduction to the design problem brings together new perspectives from prominent scientists and philosophers including Paul Davies, Richard Swinburne, Sir Martin Rees, Michael Behe, Elliot Sober and Peter van Inwagen.

The largest work ever published in the social and behavioural sciences. It contains 4000 signed articles, 15 million words of text, 90,000 bibliographic references and 150 biographical entries.

I argue that evolutionary debunking arguments are dialectically ineffective against a range of plausible positions regarding moral truth. I first distinguish debunking arguments which target the truth of moral judgements from those which target their justification. I take the latter to rest on the premise that such judgements can be given evolutionary explanations which do not invoke their truth. The challenge for the debunker is to bridge the gap between this premise and the conclusion that moral judgements are unjustified. After (...) briefly discussing older attempts to bridge this gap, I focus on Joyce’s recent attempt, which rests on the claim that ‘we do not have a believable account of how moral facts could explain the mechanisms and forces which give rise to moral judgements’. I argue that whether or not there is such an account depends on what it is permissible to assume about moral truth in this context. Further, I suggest that it is reasonable to make assumptions about moral truth which allow for the possibility of at least partial moral epistemologies. The residual challenge for the debunker is to show that these assumptions are unreasonable in a way which doesn’t render their debunking argument superfluous. (shrink)

This paper presents two cases demonstrating that theories allowing the environment to partially determine the content of moral concepts provide incorrect truth-conditions for moral terms. While typical Moral Twin Earth cases seek to establish that these theories fail to account formoral disagreement, neither case here essentially involves interpersonal disagreement. Both involve a single person retaining moral beliefs despite recognizing actual or potential mismatches with the purportedly content-determining facts. This lets opponents of such theories grant objections that standard Moral Twin Earth (...) cases fail to demonstrate disagreement, and argue more straightforwardly that they generate implausible truth-conditions for moral claims. (shrink)

It is widely held that some kinds of deception into sex (e.g., lying about what pets one likes) do not undermine the moral force of consent while other kinds of deception do (e.g., impersonating the consenter’s partner). Tom Dougherty argues against this: whenever someone is deceived into sex by the concealment of a “deal breaker” fact, the normative situation is the same as there being no consent at all. Here it is argued that this conclusion is unwarranted. Dougherty’s negative arguments (...) against alternative theories of the deceptive undermining of consent are flawed, and his two positive arguments are unjustified. (shrink)

Christine Korsgaard argues that Humean views of both action and rationality jointly imply the impossibility of irrational action, allowing us only to perform actions that we deem rational. Humeans can answer Korsgaard’s objection if their views of action and rationality measure agents’ actual desires differently. What determines what the agent does are the motivational forces that desires produce in the agent at the moment when she decides to act, as these cause action. What determines what it is rational to do (...) should be the agent’s dispositional desire strengths, as our normative intuitions respond to these. (shrink)

Nietzsche takes moral judgments to be false beliefs, and encourages us to pursue subjective nonmoral value arising from our passions. His view that strong and unified passions make one virtuous is mathematically derivable from this subjectivism and a conceptual analysis of virtue, explaining his evaluations of character and the nature of the Overman.

We explore how one might respond emotionally to the eternal recurrence. Zarathustra himself serves as our central case study. First we clarify the idea of eternal recurrence and its role in Nietzsche’s philosophy, explaining why the eternal recurrence has the emotional consequences Nietzsche describes when he first introduces the idea in The Gay Science. Then we describe Zarathustra’s emotional journey from horror at the eternal recurrence to loving it, in the sections from “On Great Events” to “The Seven Seals, or: (...) The Yes and Amen Song.”. (shrink)

I argue that Frank Jackson's knowledge argument cannot succeed in showing that qualia are epiphenomenal. The reason for this is that there is, given the structure of the argument, an irreconcilable tension between his support for the claim that qualia are non-physical and his conclusion that they are epiphenomenal. The source of the tension is that his argument for the non-physical character of qualia is plausible only on the assumption that they have causal efficacy, while his argument for the epiphenomenal (...) character of qualia is plausible only on the assumption that they are non-physical. Since these two arguments cannot be combined coherently, the most Jackson's argument can establish is that qualia are non-physical. (shrink)

This essay explains why partisanship is justified in contemporary America and environments with similar voting systems and coalition structures. It explains how political parties operate, how helping a party succeed can be a goal of genuine ethical significance, and how trusting one party while mistrusting another can be a reliable route to true belief about important political issues.

The historiography of the ‘dark age’ of biochemistry between 1910–1930 is examined. The biochemistry of the period is located within a larger contemporary debate on the interrelationship between structure and function on a submicroscopic level. It is suggested that biocolloid science was an understandable part of the historical development of biochemistry, representing a conceptual bridge between the cell biology of the late nineteenth century, and the era of structural macromolecular studies of proteins that began after 1930.

I argue that the explanatory gap is generated by factors consistent with the view that qualia are physical properties. I begin by considering the most plausible current approach to this issue based on recent work by Valerie Hardcastle and Clyde Hardin. Although their account of the source of the explanatory gap and our potential to close it is attractive, I argue that it is too speculative and philosophically problematic. I then argue that the explanatory gap should not concern physicalists because (...) it makes excessive demands on physical theory. (shrink)

I propose a new form of epiphenomenalism, 'explanatory epiphenomenalism', the view that the identification of A's mental properties does not provide a causal explanation of A's behaviour. I arrive at this view by showing that although anomalous monism does not entail type epiphenomenalism (despite what many of Davidson's critics have suggested), it does (when coupled with some additional claims) lead to the conclusion that the identification of A's reasons does not causally explain A's behaviour. I then formalize this view and (...) show that it is an attractive position, because it captures the insights of existing forms of epiphenomenalism without their onerous metaphysical commitments. (shrink)

En utilisant le cadre théorique développé par Jaegwon Kim, soit l’opposition entre le réalisme explicatif et l’irréalisme explicatif, ainsi que quelques observations sur la métaphysique et l’épistémologie de l’explication, je réexamine le désaccord opposant Robert Kane à Richard Double au sujet du principe de l’explication rationnelle. Je défends la position de Kane sur la double rationalité et je soutiens que le principe proposé par Double possède un champ d’application plus limité qu’il le prétend. Je montre aussi que, contrairement à ce (...) que suppose Double, la façon dont Kane entend expliquer l’action ne se transforme pas en une forme d’irréalisme explicatif. (shrink)

I argue that the Doctrine of Double Effect is accepted because of unreliable processes of belief-formation, making it unacceptably likely to be mistaken. We accept the doctrine because we more vividly imagine intended consequences of our actions than merely foreseen ones, making our aversions to the intended harms more violent, and making us judge that producing the intended harms is morally worse. This explanation fits psychological evidence from Schnall and others, and recent neuroscientific research from Greene, Klein, Kahane, and Schaich (...) Borg. It explains Mikhail and Hauser’s “universal moral grammar” and an interesting phenomenon about Double Effect cases noted by Bennett. When unequally vivid representations determine our decisions, we typically misjudge the merits of our options and make mistakes. So if Double Effect is a product of unequal vividness, it is likely to be mistaken. This argument, I claim, fits Berker’s specifications for good empirically grounded arguments in ethics. (shrink)

Are moral properties intellectually indispensable, and, if so, what consequences does this have for our understanding of their nature, and of our talk and knowledge of them? Are mathematical objects intellectually indispensable, and, if so, what consequences does this have for our understanding of their nature, and of our talk and knowledge of them? What similarities are there, if any, in the answers to the first two questions? Can comparison of the two cases shed light on which answers are most (...) plausible in either case? This chapter – the introduction to the volume Explanation in Ethics and Mathematics – elucidates these questions and sketches their history. (shrink)

Ethical subjectivists hold that moral judgements are descriptions of our attitudes. Expressivists hold that they are expressions of our attitudes. These views cook with the same ingredients – the natural world, and our reactions to it – and have similar attractions. This Element assesses each of them by considering whether they can accommodate three central features of moral practice: the practicality of moral judgements, the phenomenon of moral disagreement, and the mind-independence of some moral truths. In the process, several different (...) versions of subjectivism are distinguished and key expressivist notions such as 'moral attitudes' and 'expression' are examined. Different meanings of 'subjective' and 'relative' are examined and it is considered whether subjectivism and expressivism make ethics 'subjective' or 'relative' in each of these senses. (shrink)

Commentators on P.F. Strawson’s reactive attitudes emphasize the opposition between the participant and objective attitudes. This tendency overlooks Strawson’s attempt to mitigate what he saw as “a crude opposition” between these two perspectives. Strawson called attention to phenomena involving the “half-suspension” of reactive attitudes, or the “straddling” of the objective and participant stances in order to diminish this crudity. This has been largely ignored in the literature, and as a result, the phenomena that Strawson mentions are poorly understood. Drawing on (...) the work in the philosophy of emotion by Amélie Rorty and a multidimensional account of the reactive attitudes, we provide a framework to explain how such a half-suspension is possible and highlight some of its more prominent features. (shrink)

Provides an introduction to the discipline of philosophy, and includes information on the well-known figures in the field.

Philosophers who advocate the possibility of spectrum inversion often conclude that the qualitative content of experiential states pose a serious problem for functionalism. I argue that in order for the inversion hypothesis to support this conclusion one needs to show that it generalizes to all species of qualia. By examining features of touch, taste, and olfactory sensations, I show there is good reason to resist this generalization, in which case appeals to the possibility of spectral inversion are considerably less effective (...) than they may initially appear. (shrink)

This chapter -- the first in the edited collection "The Naturalistic Fallacy" (Cambridge University Press 2019) -- locates the naturalistic fallacy within the context of the other claims Moore defends in Principia Ethica. I explore the notions of “definition” and “analysis” as Moore understood them and set out in detail the multiple interpretations of the fallacy and open question argument. I then take a broad view of the influence of the fallacy on the Century of metaethics that came after Moore, (...) covering topics such as the non-cognitivist appropriation of the open question argument, the mid-Century Humean turn in which the inferential form of the fallacy was dominant, and the fallacy’s role – at the end of the Century – in framing new forms of naturalism. Finally, I argue that these multiple strands of influence demonstrate that, to a large extent, contemporary ethics – and metaethics in particular – can be understood through the framing lens of the naturalistic fallacy. (shrink)

At the turn of the twentieth century, G.E. Moore contemptuously dismissed most previous 'ethical systems' for committing the 'Naturalistic Fallacy'. This fallacy – which has been variously understood, but has almost always been seen as something to avoid – was perhaps the greatest structuring force on subsequent ethical theorising. To a large extent, to understand the Fallacy is to understand contemporary ethics. This volume aims to provide that understanding. Its thematic chapters – written by a range of distinguished contributors – (...) introduce the history, text and philosophy behind Moore's charge of fallacy and its supporting 'open question' argument. They detail how the Fallacy influenced multiple traditions in ethics, its connections to supposed dichotomies between 'is'/'ought' and facts/values, and its continuing relevance to our understanding of normativity. Together, the chapters provide a historical and opinionated introduction to contemporary ethics that will be essential for students, teachers and researchers. (shrink)

Written for any readers interested in better harnessing philosophy’s real value, this book covers a broad range of fundamental philosophical problems and certain intellectual techniques for addressing those problems. In Introducing Philosophy: God, Mind, World, and Logic , Neil Tennant helps any student in pursuit of a ‘big picture’ to think independently, question received dogma, and analyse problems incisively. It also connects philosophy to other areas of study at the university, enabling all students to employ the concepts and techniques (...) of this millennia-old discipline throughout their college careers – and beyond. KEY FEATURES AND BENEFITS: -- Investigates the philosophy of various subjects , helping students contextualize philosophy and view it as an interdisciplinary pursuit; also helps students with majors outside of philosophy to see the relationship between philosophy and their own focused academic pursuits -- Author comes from a distinguished background in Logic and Philosophy of Language, which gives the book a level of rigor, balance, and analytic focus sometimes missing from primers to philosophy -- Introduces students to various important philosophical distinctions providing skills that are important for undergraduates to develop in order to inform their study at higher levels. They are essential for further work in philosophy but they are also very beneficial for students pursuing most other disciplines -- Is much more methodologically comprehensive than competing introductions, giving the student the ability to address a wide range of philosophical problems – and not just the ones reviewed in the book -- Offers a companion website with links to apt primary sources, organized chapter-by-chapter, making unnecessary a separate Reader/Anthology of primary sources – thus providing students with all reading material necessary for the course -- Provides five to ten discussion questions for each chapter, helping instructors and students better interact with the ideas and concepts in the text. (shrink)

The roles of small and great books, and passionate yet well-considered writings in the general education of a “college” or “university” trained teacher are questions which should be turned back upon the historian as teacher and writer. Where resides the historian's classroom? Who are the students and how do teachers come to be? What subject matter should be used to prod and provoke an often dormant humanity awake? Professor Marc Bloch's work, his passion for history's rôles and its voices from (...) the past speaking to the present, had a Renaissance in the cauldron of World War II. Bloch's commitment to teaching and writing history, teaching about the forceful, or surprising and shocking, “presences” of history's supposed past-tense experiences, remains seminal to the historian's craft. Bloch's own voice from the past was forged in an intensity of present-time experience. Reflection was searing experience. Memory was “now” and remembrance was an accident of preservation for futures then unknown. These futures need to know of the experiences of former, fragile, personal and generational memories if the very same futures were to be lived more surely and securely. Marc Bloch's The Historian's Craft, remains a vindication of the human-centred, purposive roles of history in a general education. Moreover, this general education can now be said to cover the broad sweep of “secondary schooling” experiences. This sweep of schooling and post-schooling experiences is beginning, however tentatively and problematically, to extend itself into worlds of work, the futures of work and the academic futures or courses of higher education: the arena of tertiary and university education. In a not dissimilar fashion but in an even more intense spirit, Bloch's work, L’étrange défaite, examines the explosion and implosion of France and, in effect, Western Europe in the years, months and days leading up to the German offensive in the West of 10 May 1940. Bloch recognized that education and the failures to harness intellect, true intellectual freedom and innovative teaching weighed heavily upon the disastrous course of events in 1940. Professor Bloch's texts can serve two complementary purposes. First, his works, Strange Defeat and The Historian's Craft remain as significant, contemporary records of personal thoughts, argumentative methodologies, and recollections of world-shattering events. They constitute, quite literally, an historian's craft in action. Second, Bloch's texts can serve an equally valuable role where the writer seeks to take his reader through and beyond the immediate historical question, methodology or series of unravelling events into an intellectual duel which stands upon the historian's engagement with worlds, past and present. Questions and actions, makings and doings matter in this world. Understanding is not only a prime responsibility of the historian; it is a duty which might well prove dangerous. Given the above observations, this essay will seek to emphasize that world history and the teaching of broad histories of humanity recognizes few, if any, borders which seek to block or hold at bay the presentation of the “passport” known as understanding. Teaching history is much more than teaching civics or recognizing civilizational variety and its barbarous opposites. Teaching history is an act, however imperfect, of recognizing ourselves in time. My brother “schoolmasters”—when it came to the point, you did, for the most part, put up a magnificent fight. It was your goodwill which managed to create in many a sleepy secondary school, in many universities—prisoners of the worse routines the only form of education of which, perhaps, we can feel genuinely proud. I only hope that a day will come, and come soon, a day of glory and of happiness for France, when, liberated from the enemy, and freer than ever in our intellectual life, we may meet again for the mutual discussion of ideas. And when that happens, do you not think that, having learned from an experience so dearly purchased, you will find much to alter in the things you were teaching only a few years back? Strange Defeat, 142).1 What was at stake was a geological upheaval of thought …2. (shrink)

In Thus Spoke Zarathustra, Nietzsche presents passion as constituting human agency. He encountered this Humean view in Schopenhauer, and recognized its explanatory advantages over Platonic and Kantian rationalism. Zarathustra's poetic speeches anticipate and address contemporary objections to the view that passion constitutes agency. "On the Despisers of the Body" explains why understanding the self as constituted by passion provides better explanations of reasoning, value judgment, and the unity of the self than Christine Korsgaard's neo-Kantian view. "On Enjoying and Suffering the (...) Passions" explains why understanding virtues as constituted by passions provides a better explanation of moral phenomenology than John McDowell's rationalism. (shrink)

John McDowell claims that virtuous people recognize moral reasons using a perceptual capacity that doesn't include desire. I show that the phenomena he cites are better explained if desire makes us see considerations favoring its satisfaction as reasons. The salience of moral considerations to the virtuous, like the salience of food to the hungry, exemplifies the emotional and attentional effects of desire. I offer a desire-based account of how we can follow uncodifiable rules of common-sense morality and how some reasons (...) can be silenced in deliberation. I conclude by arguing that animals can be virtuous by having the right desires. (shrink)