CRISPR keeps me up at night. I marvel at its potential to cure insidious genetic diseases and scourges like malaria. I shudder at the ways it might be misused to create biological weapons. What frightens me most, though, is what I can't predict: how will we use CRISPR? How will it change evolution? How will it redefine the very nature of our existence?CRISPR is an ingenious cut-and-paste system that homes in on a particular DNA gene sequence and then, using Cas9 (...) enzymes, snips it out. That sequence is then replaced with a new one that rewrites or repairs the original. Two different cells—somatic, from the body, and germline, from gametes—can be manipulated... (shrink)

The soda wars have taken a new turn. No longer is it a battle between Coke and Pepsi to see who wins in a blind taste test. Today's soda war is between the consumer and the gigantic multinational beverage companies whose sales are plummeting. Evidence is pointing to sodas as one of the major contributors to obesity, and taxes are being slapped on what many are now calling "liquid candy."Sugar-sweetened beverages and their purveyors have been around for over a century, (...) but not until recently have they come under attack by public health officials and nutritionists. One reason these companies have sailed by for years relatively unscathed is that they have done an astonishing job at telling their story to the public... (shrink)

In a television news documentary series such as Boston Med, doctors’ duty to their patients may be at odds with the duty of TV journalists to their audience. If this happens, who should win out? The patients. If there is any possibility that harm is being done to patients, we must put them first, and turn off the cameras.

If physicians and health practitioners could do one thing to markedly improve the health of their patients, what could that be? Counsel them to reduce or stop drinking sugar-sweetened beverages.The science is clear: sodas, juice drinks, iced teas, and vitamin, sports, and energy drinks provide the largest source of empty or non-nutritional calories in the American diet and accounted for an astonishing 46% of all added sugars consumed in 2010. Sodas top the list of all sugar-sweetened beverages consumed, with the (...) soda industry producing nearly one 12-ounce serving per person per day in 2011.While it's true that sugar consumption has decreased in recent years... (shrink)

How can we as health-care providers, along with those committed to advocating for health-care equity, draw on our work to tell stories that can make a difference in people’s lives? As a pediatrician and television writer, I’m in the unique position to promote public health through dramatic television stories that are grounded in data. By telling emotionally compelling stories that are informed by peer-reviewed research, we can improve public health, particularly in these COVID-19 times, when conspiracies and anecdotes swirl around (...) and crowd out the science.Today, all of us are fixated on what it means to be infectious, derived from the Latin inficere, “to spoil or stain.” The word itself is emotionally resonant... (shrink)

Comprising eight revised essays and seven new pieces, this work provides a comprehensive resource for students, scientists, bioethicists, physicians, and laypeople to better understand and discuss the ethical issues underlying this technology that has the potential to forever change the world.