This Perspective adapts the ViolEx Model, a framework validated in several clinical conditions, to better understand the role of expectations in the recovery and/or maintenance of musculoskeletal pain. Here, particular attention is given to the condition in which dysfunctional expectations are maintained despite no longer being supported by confirmatory evidence. While the ViolEx Model suggests that cognitive immunization strategies are responsible for the maintenance of dysfunctional expectations, we suggest that such phenomenon can also be understood from a Bayesian Brain perspective, (...) according to which the level of precision of the priors is the determinant factor accounting for the extent of priors’ updating. Importantly, this Perspective translates the theory behind these two frameworks into clinical suggestions. Precisely, it is argued that different strategies should be implemented when treating MSK pain patients, depending on the nature of their expectations. (shrink)

Abstract: Nietzsche’s famously wrote that “consciousness is a surface” (EH, Why I am so clever, 9: 97). The aim of this paper is to make sense of this quite puzzling contention—Superficiality, for short. In doing this, I shall focus on two further claims—both to be found in Gay Science 354—which I take to substantiate Nietzsche’s endorsement of Superficiality. The first claim is that consciousness is superfluous—which I call the “superfluousness claim” (SC). The second claim is that consciousness is the source (...) of some deep falsification—which I call the “falsification claim” (FC). I shall start by considering Nietzsche’s notion of consciousness. Here, I shall argue that the kind of consciousness he is concerned with is in fact self-consciousness and that he put forward a higher-order theory of it. Then, I shall address the two claims. Regarding (FC), my proposal will be that, according to Nietzsche, the content of (self-)conscious mental states is falsified in virtue of its being articulated propositionally. Regarding (SC), I shall claim that it is best read as a weak version of epiphenomenalism about conscious causation. In addressing both points, I shall discuss in particular the influential reading of Nietzsche’s theory of consciousness offered by Katsafanas (2005). (shrink)

Evidentialism is the thesis, roughly, that one’s beliefs should fit one’s evidence. The enkratic principle is the thesis, roughly, that one’s beliefs should "line up" with one’s beliefs about which beliefs one ought to have. While both theses have seemed attractive to many, they jointly entail the controversial thesis that self-misleading evidence is impossible. That is to say, if evidentialism and the enkratic principle are both true, one’s evidence cannot support certain false beliefs about which beliefs one’s evidence supports. Recently, (...) a number of epistemologists have challenged the thesis that self-misleading evidence is impossible on the grounds that misleading higher-order evidence does not have the kind of strong and systematic defeating force that would be needed to rule out the possibility of such self-misleading evidence. Here I respond to this challenge by proposing an account of higher-order defeat that does, indeed, render self-misleading evidence impossible. Central to the proposal is the idea that higher-order evidence acquires its normative force by influencing which conditional beliefs it is rational to have. What emerges, I argue, is an independently plausible view of higher-order evidence, which has the additional benefit of allowing us to reconcile evidentialism with the enkratic principle. (shrink)

We often have reason to doubt our own ability to form rational beliefs, or to doubt that some particular belief of ours is rational. Perhaps we learn that a trusted friend disagrees with us about what our shared evidence supports. Or perhaps we learn that our beliefs have been afflicted by motivated reasoning or other cognitive biases. These are examples of higher-order evidence. While it may seem plausible that higher-order evidence should impact our beliefs, it is less clear how and (...) why. Normally, when evidence impacts our beliefs, it does so by virtue of speaking for or against the truth of theirs contents. But higher-order evidence does not directly concern the contents of the beliefs that they impact. In recent years, philosophers have become increasingly aware of the need to understand the nature and normative role of higher-order evidence. This is partly due to the pervasiveness of higher-order evidence in human life. But it has also become clear that higher-order evidence plays a central role in many epistemological debates, spanning from traditional discussions of internalism/externalism about epistemic justification to more recent discussions of peer disagreement and epistemic akrasia. This volume brings together, for the first time, a distinguished group of leading and up-and-coming epistemologists to explore a range of issues about higher-order evidence. (shrink)

Nowadays, almost everyone seems to agree that science is facing an epistemological crisis – namely the replicability crisis – and that we need to take action. But as to precisely what to do or how...

Many theories of rational belief give a special place to logic. They say that an ideally rational agent would never be uncertain about logical facts. In short: they say that ideal rationality requires "logical omniscience." Here I argue against the view that ideal rationality requires logical omniscience on the grounds that the requirement of logical omniscience can come into conflict with the requirement to proportion one’s beliefs to the evidence. I proceed in two steps. First, I rehearse an influential line (...) of argument from the "higher-order evidence" debate, which purports to show that it would be dogmatic, even for a cognitively infallible agent, to refuse to revise her beliefs about logical matters in response to evidence indicating that those beliefs are irrational. Second, I defend this "anti-dogmatism" argument against two responses put forth by Declan Smithies and David Christensen. Against Smithies’ response, I argue that it leads to irrational self-ascriptions of epistemic luck, and that it obscures the distinction between propositional and doxastic justification. Against Christensen’s response, I argue that it clashes with one of two attractive deontic principles, and that it is extensionally inadequate. Taken together, these criticisms will suggest that the connection between logic and rationality cannot be what it is standardly taken to be—ideal rationality does not require logical omniscience. (shrink)

Orthodox Bayesianism is a highly idealized theory of how we ought to live our epistemic lives. One of the most widely discussed idealizations is that of logical omniscience: the assumption that an agent’s degrees of belief must be probabilistically coherent to be rational. It is widely agreed that this assumption is problematic if we want to reason about bounded rationality, logical learning, or other aspects of non-ideal epistemic agency. Yet, we still lack a satisfying way to avoid logical omniscience within (...) a Bayesian framework. Some proposals merely replace logical omniscience with a different logical idealization; others sacrifice all traits of logical competence on the altar of logical non-omniscience. We think a better strategy is available: by enriching the Bayesian framework with tools that allow us to capture what agents can and cannot infer given their limited cognitive resources, we can avoid logical omniscience while retaining the idea that rational degrees of belief are in an important way constrained by the laws of probability. In this paper, we offer a formal implementation of this strategy, show how the resulting framework solves the problem of logical omniscience, and compare it to orthodox Bayesianism as we know it. (shrink)

In this paper I analyze a case of extreme response to need of security in the landscape of advanced democracies: the role of Golden Dawn in the management and reproduction of the profound socio-economic crisis in Greece. I argue that the keys behind the success of such a party are to be found in two distinct but self-reinforcing elements: its organizational strength and its anti-system ideology. The most significant organizational structures and activities which transformed Golden Dawn into a quasi-mafia style (...) “industry of private protection” are thus investigated, along with the most important contents of its radical and anti-systemic message. (shrink)

The institutionalization of a rights-based proportionality review shares a number of salient features and puzzles with the practice of contestation that the Socrates of the early Platonic dialogues became famous for. Understanding the point of Socratic contestation, and its role in a democratic polity, is also the key to understanding the point of proportionality based rights review. To begin with, when judges decide cases within the proportionality framework they do not primarily interpret authority. They assess reasons. Not surprisingly, they, like (...) Socrates, have been prone to the charge that they offend the values and traditions of the community. The article discusses four types of pathologies that occasionally infect democratic decision-making that rights-based proportionality review is particularly suited to identify. But more basic and equally important is a second kind of justification: Proportionality-based judicial review institutionalizes a right to contest the acts of public authorities and demand a public reasons-based justification. Having a legal remedy that allows for the contestation of acts by public authorities before an impartial and independent court and demanding its justification in terms of public reason is as basic a commitment of liberal democracy as the right to vote. The real question is not whether judicial review is democratically legitimate, but how judicial institutions ought to be structured to best serve their democracy-enhancing and rights protecting purpose. If Socrates was right to insist that the practice of contestation he engaged in deserves the highest praise in a democratic polity, it is equally true that a well structured and appropriately embedded court engaged in rights based proportionality review deserves to be embraced as a vital element of liberal constitutional democracy. (shrink)

In this paper, we present a new semantic framework designed to capture a distinctly cognitive or epistemic notion of meaning akin to Fregean senses. Traditional Carnapian intensions are too coarse-grained for this purpose: they fail to draw semantic distinctions between sentences that, from a Fregean perspective, differ in meaning. This has led some philosophers to introduce more fine-grained hyperintensions that allow us to draw semantic distinctions among co-intensional sentences. But the hyperintensional strategy has a flip-side: it risks drawing semantic distinctions (...) between sentences that, from a Fregean perspective, do not differ in meaning. This is what we call the ‘new problem’ of hyperintensionality to distinguish it from the ‘old problem’ that faced the intensional theory. We show that our semantic framework offers a joint solution to both these problems by virtue of satisfying a version of Frege’s so-called ‘equipollence principle’ for sense individuation. Frege’s principle, we argue, not only captures the semantic intuitions that give rise to the old and the new problem of hyperintensionality, but also points the way to an independently motivated solution to both problems. (shrink)

The traditional possible-worlds model of belief describes agents as ‘logically omniscient’ in the sense that they believe all logical consequences of what they believe, including all logical truths. This is widely considered a problem if we want to reason about the epistemic lives of non-ideal agents who—much like ordinary human beings—are logically competent, but not logically omniscient. A popular strategy for avoiding logical omniscience centers around the use of impossible worlds: worlds that, in one way or another, violate the laws (...) of logic. In this paper, we argue that existing impossible-worlds models of belief fail to describe agents who are both logically non-omniscient and logically competent. To model such agents, we argue, we need to ‘dynamize’ the impossible-worlds framework in a way that allows us to capture not only what agents believe, but also what they are able to infer from what they believe. In light of this diagnosis, we go on to develop the formal details of a dynamic impossible-worlds framework, and show that it successfully models agents who are both logically non-omniscient and logically competent. (shrink)

When a belief has been influenced, in part or whole, by factors that, by the believer's own lights, do not bear on the truth of the believed proposition, we can say that the belief has been, in a sense, arbitrarily formed. Can such beliefs ever be rational? It might seem obvious that they can't. After all, belief, supposedly, “aims at the truth.” But many epistemologists have come to think that certain kinds of arbitrary beliefs can, indeed, be rational. In this (...) paper, I want to do two things. First, I want to show that the claim that arbitrary beliefs can be rational is inconsistent with the conjunction of two other attractive claims: one saying that rationality requires a certain kind of epistemic immodesty, and one saying that rationality forbids certain kinds of self-ascriptions of epistemic luck. Second, I want to evaluate different ways one might respond to this inconsistent triad. I won't defend any response in particular, but I'll draw out some notable costs and benefits of each response, which may help shed light on the question of whether arbitrary beliefs can be rational. (shrink)

Self‐admission to inpatient treatment is a novel approach that aims to increase agency and autonomy for patients with severe psychiatric illness and a history of high utilization of inpatient care. By focusing on brief, preventive hospital admissions in times of increased risk of relapse, self‐admission seeks to reduce the need for prolonged episodes of inpatient treatment. Participants are generally satisfied with the model, which is not surprising given that self‐admission programs allocate a scarce resource—hospital beds—to a select group. However, the (...) patients targeted by these programs are not necessarily those in most need of hospital admission, which may compromise the commonly accepted ‘principle of need’ in allocation of public healthcare resources. In light of the current lack of consistent evidence of the usefulness and cost‐effectiveness of the model, several aspects need to be further studied in order to guide any large‐scale implementation of self‐admission in psychiatry. (shrink)

The present paper investigates the seventeenth-century debate on whether the agreement of all human beings upon certain notions—designated as the “common” ones—prove these notions to be innate. It does so by focusing on Descartes’ and Locke’s rejections of the philosophy of Herbert of Cherbury, one of the most important early modern proponents of this view. The paper opens by considering the strategy used in Herbert’s arguments, as well as the difficulties involved in them. It shows that Descartes’ 1638 and 1639 (...) reading of Herbert’s On Truth—both the 1633 second Latin edition and Mersenne’s 1639 translation—was instrumental in shaping Descartes’ views on the issue. The arguments of Locke’s Essay opposing Herbert’s case for innatism are thus revealed to be ineffective against the case which Descartes makes for this same doctrine, since Descartes had in fact framed his conception of innateness in opposition to the very same theses as Locke was arguing against. The paper concludes by explaining how two thinkers as antithetical as Locke and Descartes came to agree on at least one point, and a truly crucial one: namely, that universal consent counts as a criterion neither for innatism nor for truth. (shrink)

Nietzsche believes that we do not know our own actions, nor their real motives. This belief, however, is but a consequence of his assuming a quite general skepticism about introspection. The main aim of this paper is to offer a reading of this last view, which I shall call the Inner Opacity (IO) view. In the first part of the paper I show that a strong motivation behind IO lies in Nietzsche’s claim that self-knowledge exploits the same set of cognitive (...) capacities as well as the same folk-psychological framework involved in outward-directed mind-reading. In the second part I turn to Nietzsche’s view of agency and argue that he sees a fundamental discrepancy between the conscious attitudes we have introspective access to, on the one hand, and the subpersonal processes and states occurring at the unconscious level of the drives, on the other hand. (shrink)

Do I cause global warming, climate change and their related harms when I go for a leisure drive with my gas-guzzling car? The current verdict seems to be that I do not; the emissions produced by my drive are much too insignificant to make a difference for the occurrence of global warming and its related harms. I argue that our verdict on this issue depends on what we mean by ‘causation’. If we for instance assume a simple counterfactual analysis of (...) causation according to which ‘C causes E’ means ‘if C had not occurred, E would not have occurred’, we must conclude that a single drive does not cause global warming. However, this analysis of causation is well-known for giving counterintuitive results in some important cases. If we instead adopt Lewis’s analysis of causation, it turns out that it is indeterminate whether I cause global warming when I go for a single drive. Still, in contexts where we seek to control or understand global warming, there is a pressure to adopt a more fragile view of this event. When we adopt such a view, it turns out that a single drive does cause global warming. This means that we cannot like Sinnott-Armstrong and Kingston and Sinnott-Armstrong reject the idea that I should refrain from going for a leisure drive simply because such a drive does not cause global warming. (shrink)

Many theories of rational action are predicated on the idea that what it is rational to do in a given situation depends, in part, on what it is rational to believe in that situation. In short: they treat epistemic rationality as explanatorily prior to practical rationality. If they are right in doing so, it follows, on pain of explanatory circularity, that epistemic rationality cannot itself be a form of practical rationality. Yet, many epistemologists have defended just such a view of (...) epistemic rationality. According to them, there is no such thing as a distinctively epistemic form of rationality which could be explanatorily prior to practical rationality. Rather, they maintain, there is just one form of rationality—practical rationality—of which epistemic rationality is a species. What to make of this conflict? The aim of this paper is to motivate a view about the relationship between epistemic and practical rationality which resolves the conflict in a way that should be attractive to both sides. The central idea is to ground both epistemic and practical rationality in an independently motivated notion of evidential probability which is itself to be understood in non-normative terms. Doing so, I argue, allows us to unify epistemic and practical rationality in a way that does justice to the idea that what it is rational to do depends, in part, on what it is rational to believe; and to do so in a way that avoids explanatory circularity. (shrink)

Although the fictional domain exhibits a prima facie freedom from real-world moral constraints, certain fictive imaginings seem to deserve moral criticism. Capturing both intuitions, this paper argues for double-standard moralism, the view that fictive imaginings are subject to different moral standards than their real-world counterparts. I show how no account has, thus far, offered compelling reasons to warrant the moral appropriateness of this discrepancy. I maintain that the normative discontinuity between fiction and the actual world is moderate, as opposed to (...) one that leaves fictive engagements wholly exempt from moral evaluations. I propose a way of addressing the gamer’s dilemma that is compatible with a moderate kind of discontinuity. Finally, I contend that the audience is justified in adopting deviant moral attitudes in fictional situations because their consequences largely differ from those that analogous real-world events would have. (shrink)

Our aim in this chapter is to draw attention to what we see as a disturbing feature of conciliationist views of disagreement. Roughly put, the trouble is that conciliatory responses to in-group disagreement can lead to the frustration of a group's epistemic priorities: that is, the group's favoured trade-off between the "Jamesian goals" of truth-seeking and error-avoidance. We show how this problem can arise within a simple belief aggregation framework, and draw some general lessons about when the problem is most (...) pronounced. We close with a tentative proposal for how to solve the problem raised without rejecting conciliationism. (shrink)

The environmental crisis challenges the adequacy of traditional moral theories, particularly in the case of act consequentialism – the view that an act is morally right if and only if it brings about the best available outcome. Although anthropogenic climate change threatens the well-being of billions of humans and trillions of non-human animals, it is difficult for an act consequentialist to condemn actions that contribute to it, as each individual action makes no difference to the probability of whether climate change (...) will occur. Or so one argument goes. This chapter examines the limits and possibilities of a consequentialist approach to climate ethics. It discusses various types of consequentialist theories applicable to the current environmental situation. It outlines outcome-based strategies to address the no-difference problem and to promote individual climate action. Finally, it considers environmental cases of evaluative uncertainty and how a consequentialist could deal with them. (shrink)

We refine the intuitively appealing idea that you are blameworthy for something if it happened because you did not care enough. More formally: you are blameworthy for X (where X may be an action, omission, or outcome) just in case there is the right causal-explanatory relation between your poor quality of will and X. First, we argue that blameworthiness for actions, omissions, and outcomes is concerned with negative differences: you are blameworthy for the fact that X occurred instead of X*, (...) where X is worse than X*. Second, we argue that the way in which your quality of will is poor has to fit what you are blameworthy for. With these refinements, the account already gives intuitively correct verdicts in cases of forgetting, making a negative difference to a nevertheless good result, and doing an action with runaway consequences. We then discuss what the right causal-explanatory relation is and suggest that it is simply causation, understood in the right way. Here, we draw on the account of causation developed in Touborg, The Dual Nature of Causation. According to this account, there are two necessary and jointly sufficient conditions for causation. Roughly, C causes E rather than E* iff (a) C is process-connected to E, and (b) C makes E more secure and E* less secure. With this account of causation, our account of blameworthiness now also gives correct verdicts in omission, pre-emption, and switching cases, Frankfurt-style cases, and collective harm cases. (shrink)

Background Traditionally, palliative care has focused on patients suffering from life-threatening somatic diseases such as cancer or progressive neurological disorders. In contrast, despite the often chronic, severely disabling, and potentially life-threatening nature of psychiatric disorders, there are neither palliative care units nor clinical guidelines on palliative measures for patients in psychiatry. Main text This paper contributes to the growing literature on a palliative approach in psychiatry and is based on the assumption that a change of perspective from a curative to (...) a palliative approach could help promote patient-centeredness and increase quality of life for severely ill patients in psychiatry as well as in somatic medicine. To exemplify this, we offer three different clinical scenarios: severe and enduring anorexia nervosa, treatment-refractory schizophrenia, and chronic suicidality and persistent self-injury in borderline personality disorder. Conclusion We emphasize that many typical interventions for treatment-refractory psychiatric disorders may indeed be of a palliative nature. Furthermore, introducing traditional features of palliative care, e.g. so-called goals of care conversations, could aid even further in ensuring that caregivers, patients, and families agree on which treatment goals are to be prioritized in order to optimize quality of life in spite of severe, persistent mental disorder. (shrink)

Should you always be certain about what you should believe? In other words, does rationality demand higher-order certainty? First answer: Yes! Higher-order uncertainty can’t be rational, since it breeds at least a mild form of epistemic akrasia. Second answer: No! Higher-order certainty can’t be rational, since it licenses a dogmatic kind of insensitivity to higher-order evidence. Which answer wins out? The first, I argue. Once we get clearer about what higher-order certainty is, a view emerges on which higher-order certainty does (...) not, in fact, license any kind of insensitivity to higher-order evidence. The view as I will describe it has plenty of intuitive appeal. But it is not without substantive commitments: it implies a strong form of internalism about epistemic rationality, and forces us to reconsider standard ways of thinking about the nature of evidential support. Yet, the view put forth promises a simple and elegant solution to a surprisingly difficult problem in our understanding of rational belief. (shrink)

According to the prevailing paradigm in social-cognitive neuroscience, the mental states of individuals become shared when they adapt to each other in the pursuit of a shared goal. We challenge this view by proposing an alternative approach to the cognitive foundations of social interactions. The central claim of this paper is that social cognition concerns the graded and dynamic process of alignment of individual minds, even in the absence of a shared goal. When individuals reciprocally exchange information about each other's (...) minds processes of alignment unfold over time and across space, creating a social interaction. Not all cases of joint action involve such reciprocal exchange of information. To understand the nature of social interactions, then, we propose that attention should be focused on the manner in which people align words and thoughts, bodily postures and movements, in order to take one another into account and to make full use of socially relevant information. (shrink)

Don’t form beliefs on the basis of coin flips or random guesses. More generally, don’t take belief gambles: if a proposition is no more likely to be true than false given your total body of evidence, don’t go ahead and believe that proposition. Few would deny this seemingly innocuous piece of epistemic advice. But what, exactly, is wrong with taking belief gambles? Philosophers have debated versions of this question at least since the classic dispute between William Clifford and William James (...) near the end of the nineteenth century. Here I reassess the normative standing of belief gambles from the perspective of epistemic decision theory. The main lesson of the paper is a negative one: it turns out that we need to make some surprisingly strong and hard-to-motivate assumptions to establish a general norm against belief gambles within a decision-theoretic framework. I take this to pose a dilemma for epistemic decision theory: it forces us to either make seemingly unmotivated assumptions to secure a norm against belief gambles, or concede that belief gambles can be rational after all. (shrink)

Guessing is a familiar activity, one we engage in when we are uncertain of the answer to a question under discussion. It is also an activity that lends itself to normative evaluation: some guesses are better than others. The question that interests me here is what makes for a good guess. In recent work, Dorst and Mandelkern have argued that good guesses are distinguished from bad ones by how well they optimize a tradeoff between accuracy and specificity. Here I argue (...) that Dorst and Mandelkern’s implementation of this idea fails to satisfy some plausible constraints on good guesses, and I develop an alternative implementation that satisfies the relevant constraints. The result is a new account of good guesses which retains the positive aspects of Dorst and Mandelkern’s proposal, but without the drawbacks. (shrink)

There are many ways to advance our understanding of the human mind by studying different kinds of sociality. Our aim in this introduction is to situate claims about extended cognition within a broader framework of research on human sociality. We briefly discuss the existing landscape, focusing on ways of defending socially extended cognition. We then draw on resources from the recent literature on the socially extended mind, as well as the literature on collective intentionality, to provide a framework for thinking (...) about the social dimension of individual minds. We then turn to a brief overview of the individualistic approaches advanced by Ludwig and Spaulding in this volume. And we close with a discussion of the transformative role of the social mind in individual life presented by Kern and Moll, as well as the distributed approach to interacting systems defended by Goldstone and Theiner. (shrink)

This chapter aims to deepen Donald Schön’s insight about jazz playing as an example of what he calls “reflection-in-action” (RiA) by situating this notion within the enactive view of humans as linguistic bodies. Our main claim is that the knowl-edge or skills displayed by expert jazz musicians must be understood as aural and communicative in nature. After presenting the notions of RiA and linguistic bodies, we develop our view through a critical discussion of four statements from Schön’s passage on jazz (...) musicianship, before wrapping up and clarifying the position we are advocating. This way, we suggest a revised version of Schön’s concept, which we call “reflection in communicative jazz action.". (shrink)

Titelbaum Oxford studies in epistemology, 2015) has recently argued that the Enkratic Principle is incompatible with the view that rational belief is sensitive to higher-order defeat. That is to say, if it cannot be rational to have akratic beliefs of the form “p, but I shouldn’t believe that p,” then rational beliefs cannot be defeated by higher-order evidence, which indicates that they are irrational. In this paper, I distinguish two ways of understanding Titelbaum’s argument, and argue that neither version is (...) sound. The first version can be shown to rest on a subtle, but crucial, misconstrual of the Enkratic Principle. The second version can be resisted through careful consideration of cases of higher-order defeat. The upshot is that proponents of the Enkratic Principle are free to maintain that rational belief is sensitive to higher-order defeat. (shrink)

Igor Agostini, La démonstration de l’existence de Dieu. Les conclusions des cinq voies de saint Thomas d’Aquin et la preuve a priori dans le thomisme du XVIIe siècle, The Age of Descartes / Descart...

Statistical evidence is pervasive in medicine. In this chapter we will focus on the reliability of randomized clinical trials (RCTs) conducted to test the safety and efficacy of medical treatments. RCTs are scientific experiments and, as such, we expect them to be replicable: if we repeat the same experiment time and again, we should obtain the same outcome (Norton 2015). The statistical design of the test should guarantee that the observed outcome is not a random event, but rather a real (...) effect of the treatments administered. However, for more than a decade now, we have been discussing a replicability crisis across different experimental disciplines including medicine: the outcomes of trials published in very prestigious journals often disappear when the experiment is repeated (see, e.g., Lehrer 2010, Begley and Ellis 2012, Horton 2015). -/- There are different accounts of the reason for this replicability crisis, ranging from scientific fraud to lack of institutional incentives to double-check someone else’s results. In this chapter we will use the replicability crisis as a thread to introduce some central issues in the design of scientific experiments in medicine. First, in section 1, we will see how replicability and statistical significance are connected: we can only make sense of the p-value of a trial outcome within a series of replications of the test. But in order to conduct these replications properly, we need to agree on the proper design of the experiment we are going to repeat. In particular, we need to prevent the preferences of the experimenters from biasing the outcome of the experiment. If there is such a bias, when the experiment is replicated by a third party, the observed outcome will vanish. In section 2, we will argue that trialists need to agree on the debiasing procedures and the statistical quality controls that feature in the trial protocol, if they want the outcome to be replicable. In section 3, we will make two complementary points. On the one hand, replicability per se is not everything: we need trial outcomes that are not only statistically significant but also clinically relevant. On the other hand, trials are not everything: the experts analyzing the evidence can improve the reliability of statistical evidence, although they sometimes fail; we need to further study how they make their decisions. In section 4, we will use a controversy about the overprescription of statins to show how non-replicable effects are obtained in trials and how experts may fail at detecting such flaws, if the commercial interests are big enough. (shrink)

Review of: Lyotard and Critical Practice, Kiff Bamford and Margaret Grebowicz (eds) (2023) London: Bloomsbury, 238 pp., ISBN 978-1-35019-202-7, h/bk, GBP 85.00.

Nietzsche vs. Kant? Der siebzehnte Aphorismus aus dem ersten Teil von Menschliches, Allzumenschliches schliesst mit der korrosiven Bemerkung, das Ding an sich [sei] eines homerischen Gelachters werth. Aufgrund dieser Passage nun aber zu vermuten, Nietzsche habe diesen von Kant stammenden Terminus einfach so ad acta gelegt, ware jedoch ubereilt, denn die Auseinandersetzung mit der Unterscheidung zwischen Erscheinung und Ding an sich lasst sich als Konstante durch Nietzsches gesamtes Werk verfolgen. Mattia Riccardi widmet sich in seiner Studie den verschiedenen Positionen, (...) die Nietzsche im Zusammenhang mit dieser Problematik eingenommen hat: von der im Hintergrund der Geburt der Tragodie prasenten Artisten-Metaphysik bis zur radikalen Infragestellung des kantischen Denkmusters in den Jahren nach 1880. Riccardi beschrankt sich aber nicht auf eine historisch akkurate, direkte und indirekte Textquelle mit einbeziehender Rekonstruktion von Nietzsches kampferischer Lekturepraxis. Vielmehr stellen die wiederholt auftretenden Bezuge auf Kants Begrifflichkeit fur ihn ein geeignetes Instrument dar, um die Entfaltung von Nietzsches Denken in aller Scharfe sichtbar zu machen. Die Kritik an Kant wird auf diese Weise zum Ausgangspunkt einer differenzierten Interpretation von Nietzsches perspektivistischer Philosophie der Macht im Sinne einer relationalen Ontologie. Damit versteht sich das Buch auch als Beitrag zur - vor allem im englischsprachigen Raum sehr lebendigen - Debatte um das Verhaltnis Nietzsches zu Kant. (shrink)

According to many philosophers and scientists, human sociality is explained by our unique capacity to “share” attitudes with others. The conditions under which mental states are shared have been widely debated in the past two decades, focusing especially on the issue of their reducibility to individual intentionality and the place of collective intentions in the natural realm. It is not clear, however, to what extent these two issues are related and what methodologies of investigation are appropriate in each case. In (...) this article, I propose a solution that distinguishes between epistemic and ontological interpretations of the demand for the conditions of reduction of collective intentionality. While the philosophical debate has contributed important insights into the former, recent advances in the cognitive sciences offer novel resources to tackle the latter. Drawing on Michael Tomasello’s research in the ontogeny of shared intentionality in early instances of interaction based on joint attention, I propose an empirically informed argument of what it would take to address the ontological question of irreducibility, thus making a step forward in the naturalization of collective intentionality. (shrink)

The aim of this paper is to trace one of the deepest roots of Hegel's concept of history within Kant's doctrine of schematism. I propose to draw a line of continuity between Kant's Einbildungskraft and Hegel's Selbstbewusstsein. The concept of Selbstbewusstsein of the young Hegel is to be understood, in my view, as the moment when the extreme and radical consequences are drawn from the schematism of the first Critique, revised in the light of Kant's reflections on teleology developed in (...) the Critique of Judgment. In this sense, Hegel can be seen as the 'solution' to the rift that opened up in the heart of Western culture during the Enlightenment. (shrink)

The trope that modern Europe, emerging from its Dark Ages, is indebted to the Islamic Middle Ages is widespread. The article traces this ‘Islamic medievalism’ back to Muslim discourses of the late 19th and early 20th century. Focusing on the Egyptian intellectual Muhammad Lutfi Jum’a’s (1886-1953) portrayal of medieval Islam and its philosophers as well as his mobilization of these within a reformist ideology, it argues the following: Firstly, that Jum’a’s medievalism, perceiving medieval Islamic philosophy as the sine qua non (...) of European modernity, is indebted to readings of European orientalist histories of philosophy, demonstrating how medievalism emerged from a global discursive formation. Secondly, that Jum’a mobilized the medievalist argument and the philosophers to argue for the possibility of an alternative counter-modern Muslim and Eastern modernity where the materialist and disenchanting tendencies of European modernity are negated – a vision he shared with other so-called Easternist thinkers, who conceived of Muslim countries as belonging to a broader East ranging from North Africa to Japan. (shrink)