In this introduction, we address some of the complexities associated with the emergence of medicine’s bodies, not least as a means to ‘working with the body’ rather than simply producing a critique of medicine. We provide a brief review of some of the recent discussions on how to conceive of medicine and its bodies, noting the increasing attention now given to medicine as a technology or series of technologies active in constituting a multiplicity of entities – bodies, diseases, experimental objects, (...) the individualization of responsibility for health and even the precarity of life. We contrast what feminist theorists in the tradition of Judith Butler have referred to as the question of matter, and Science and Technology Studies with its focus on practice and the nature of emergence. As such we address tensions that exist in analyses of the ontological status of ‘the body’ – human and non-human – as it is enacted in the work of the laboratory, the randomized controlled trial, public health policy and, indeed, the market that is so frequently entangled with these spaces. In keeping with the recent turns toward ontology and affect, we suggest that we can regard medicine as concerned with the contraction and reconfiguration of the body’s capacities to affect and be affected, in order to allow for the subsequent proliferation of affects that, according to Bruno Latour, marks corporeal life. Treating both contraction and proliferation circumspectly, we focus on the patterns of affects wrought in particular by the abstractions of medicine that are described in the contributions to this special issue. Drawing on the work of A.N. Whitehead, we note how abstractions such as ‘medical evidence’, the ‘healthy human body’ or the ‘animal model’ are at once realized and undercut, mediated and resisted through the situated practices that eventuate medicine’s bodies. Along the way, we touch on the implications of this sort of perspective for addressing the distribution of agency and formulations of the ethical and the political in the medical eventuations of bodies. (shrink)

In this article I consider the field of HIV treatment and prevention in light of poststructural feminist critiques of the self-evidence of matter. Both HIV and poststructural feminist theory are viewed in relation to the current state of HIV scientific research of which it has been said: ‘much remains left to the imagination’ (McCune, 2001, emphasis added). Importantly, it is in the absence of ‘real’ knowledge of bodily matter and virus, that imagination is presumed by science as a fall back. (...) Paradoxically, recent debate within feminist theory provides an almost perverse counter to this way of characterizing the struggle against HIV. Rather than considering imagination as something outside or external to the ‘real’, there is now substantial argument suggesting that imagination is always already present and inherent to the ‘real’. In the course of this paper, these differing positions of science and feminist theory are used to challenge and extend each other. The empirical matter of HIV medical science is shown as evidence of matter beyond the normative insistence of (human) language. On this basis, a theory of performativity - devised by Judith Butler and extended by Karen Barad - is argued as grounds for a methodologically expanded science. (shrink)

In this article we explore how two enactments of HIV – the UN’s AIDS Clock and clinical trials for an HIV biomedical prevention technology or pre-exposure prophylaxis – entail particular globalizing and localizing dynamics. Drawing on Latour’s and Whitehead’s concept of proposition, and Serres’ call for a philosophy of prepositions, we use the composite notion of pre/pro-positions to trace the shifting topological status of HIV. For example, we show how PrEP emerges through topological entwinements of globalizing biomedical standardization, localizing protests (...) against PrEP trials and globalizing ethical principles. We go on to examine how our own analysis manifests a parallel topological pattern in which we deploy a globalizing argument about the localizing of the globalizing found in the AIDS Clock and the PrEP trails. Finally, we consider how the movement of ‘topology’ into the social sciences might itself benefit from a topological treatment. (shrink)

This article explores problems posed by HIV anti-retroviral combination therapies by focusing on the UK media promotion of Trizivir (a GlaxoSmithKline three-drugs-in-one tablet). Using the substance of the figural in the style of feminist critiques of science and borrowing from actor network theory, a synergistic relationship comprising HIV, anti-HIV drugs, drug manufacturers and their media, medical publications, consumer representative treatment information and mass media is shown to construct a worrisome set of choices. The coming together of otherwise divergent interests and (...) media raises questions about a certain adherence to drug manufacturer ‘facts’. But more provocative is the Trizivir campaign itself. For it suggests a stridency that goes well beyond the limits of its choices and, in doing so, offers the possibility for renewed consumer activism. (shrink)

This photo-essay highlights the ways in which medicine features in the Occupied Palestinian Territories (OPT) and uses it to reflect on the nature of ethical obligation set out by Judith Butler in her work on state-achieved precarity. Although medical infrastructure of even the most basic type is tragically lacking and in some areas shockingly absent in the OPT, it is the particular way in which medicine comes to be needed that we focus on. Leaving aside the rhetoric that has claimed (...) authority over what can or cannot be said of the Occupation, we focus on its geo-technological arrangements. By placing photos and case studies of medical obstruction within an analysis of the Occupation, we forge an encounter between reader and the Occupation to raise questions about the use of medicine in this context and the manner in which conventional ethics can give legitimacy to this use. On the basis of what we show through visual and textual documentary material, we propose ethics be understood as inherent to the geo-technological arrangements that make life possible or, as in this case, undermine, obstruct or deliberately take life. Hence the ethical obligation that Butler calls upon is reiterated in ways that encompass the everyday features of occupation including those active in the emergence of medicine as a tactic of war. (shrink)