Background Thirst and dry mouth are common symptoms in terminally ill patients. In their day-to-day practice, palliative care physicians regularly encounter ethical dilemmas, especially regarding artificial hydration. Few studies have focused on thirst and the ethical dilemmas palliative care physicians encounter in relation to this, leading to a knowledge gap in this area. Aim The aim of this study was to explore palliative care physicians’ experiences of ethical challenges in relation to thirst in terminally ill patients. Methods A qualitative interview (...) study with an inductive approach was conducted. Sixteen physicians working in four different specialised palliative care units and one geriatric care unit in different hospitals in Sweden were interviewed. The interviews were transcribed verbatim and analysed with a reflexive thematic analysis. Results When presented with an ethical challenge relating to thirst, physicians attempted to balance benefits and harms while emphasizing respect for the patient’s autonomy. The ethical challenges in this study were: Starting, continuing or discontinuing drips; lack of evidence and traditions create doubt; and lack of interest and time may result in patient suffering. Conclusions All physicians in this study reported that “Starting, continuing or discontinuing drips” was the main ethical challenge they encountered, where some were so accustomed to the decision that they had a standard answer ready to offer patients and families. Physicians reported that drips were a symbol of thirst quenching, life and survival but were not necessary in end-of-life care. Others questioned the traditions regarding thirst and emphasised drips in particular. (shrink)

The ability to reason and think in a logical manner forms the basis of learning for most mathematics, computer science, philosophy and logic students. Based on the author's teaching notes at the University of Maryland and aimed at a broad audience, this text covers the fundamental topics in classical logic in an extremely clear, thorough and accurate style that is accessible to all the above. Covering propositional logic, first-order logic, and second-order logic, as well as proof theory, computability theory, and (...) model theory, the text also contains numerous carefully graded exercises and is ideal for a first or refresher course. (shrink)

Can a man intend to do the impossible? That is, can a man undertake to do some action, A—and not merely to come as close as possible to doing A with the hope that the doing of A will result—when he believes he has no chance of doing A?

Razón, poesía, historia.--La cuestión del estoicismo español.--El querer.

Dibujar el pensamiento de Seneca es dibujar su figura viva, trazar el esquema de su persona. Seneca es un mediador que para alzarse sobre nosotros necesita de nuestra necesidad, pues solo apoyado en nuestra indigencia tiene sentido. Maria Zambrano lleva a cabo un lucido estudio de la figura y significacion del pensador cordobes y presenta una seleccion de sus escritos.

Spectroscopy is a scientific topic at the interface between Chemistry and Physics, which is taught at high school level in relation with its fundamental applications in Analytical Chemistry. In the first part of the paper, the topic of spectroscopy is analyzed having in mind the well-known Johnstone’s triangle of chemistry education, putting in evidence the way spectroscopy is usually taught at the three levels of chemical knowledge: macroscopic/phenomenological, sub-microscopic/molecular and symbolic ones. Among these three levels, following Johnstone’s recommendations the macroscopic (...) one is the most useful for high school students who learn spectroscopy for the first time. Starting from these premises, in the second part of the paper, we propose a didactic sequence which is inspired by the historical evolution of spectroscopic instruments from the first spectroscopes invented by Gustav Kirchhoff and Robert Bunsen in 1860 to the UV–vis spectrophotometers which became common since the 1960s. The idea behind our research is to analyze the conceptual advancements through the history of spectroscopy and to identify the key episodes/experiments and spectroscopic instruments. For each of them, a didactic activity, typically an experiment, is then proposed underlining the relevant aspects from the chemistry education point of view. The present paper is the occasion to reflect on the potentialities of an historical approach combined with a laboratorial one, and to discuss the role of historical instruments and related technological improvements to teach spectroscopy. (shrink)

Hilary Putnam is one of the world’s leading philosophers. His highly original and often provocative ideas have set the agenda for a variety of debates in philosophy of science, philosophy of mind and philosophy of language. His now famous philosophical thought experiments, such as the ‘Twin earth’ and ‘the brains in the vat’ have become part of the established canon in philosophy and cognitive science. _Reading Putnam_ is an outstanding overview and assessment of Hilary Putnam’s work by a team of (...) international contributors, and includes replies by Putnam himself. Divided into clear sections, it contains chapters on key aspects of Putnam’s large body of writing, including: Scientific realism and the changes that Putnam’s thought has undergone on this topic analyticity and ontology, including the important interconnections between the views of Putnam and Quine Putnam’s arguments concerning externalist views of meaning and reference, questions of conceptual relativity, and his preoccupation with ethics through a denial of the fact–value dichotomy Putnam’s developing views on perception. Offering an excellent survey of Putnam’s work, _Reading Putnam_ is essential for those studying philosophy of mind, philosophy of language, and philosophy of science, as well as for anyone interested in contemporary philosophy. (shrink)

In the literature, the pragmatic dimension of metaphors has been clearly acknowledged. Metaphors are regarded as having different possible uses, especially pursuing persuasion. However, an analysis of the specific conversational purposes that they can be aimed at achieving in a dialogue and their adequacy thereto is still missing. In this chapter, we will address this issue focusing on the classical distinction between the explanatory and persuasive uses of metaphors, which is, however, complex to draw at an analytical level and often (...) blurred and controversial also from a theoretical point of view. Building on the analysis of explanation in different theories and fields of study, we show how it can be conceived as characterized by a cognitive and a pragmatic dimension, where the transference of understanding is used pragmatically for different dialogical goals - such as informing, making a joint decision, and most importantly persuading. In this sense, the cognitive effects of understanding are not incompatible with a persuasive dialogical purpose. This theoretical proposal will be applied to examples drawn from the medical context, to show how a pragmatic approach to explanation can account for the complexity of the cases that can be found in actual dialogical contexts. (shrink)

Phosphatidylinositol 4,5‐bisphosphate (PI4,5P2) is a key lipid signaling molecule that regulates a vast array of biological activities. PI4,5P2 can act directly as a messenger or can be utilized as a precursor to generate other messengers: inositol trisphosphate, diacylglycerol, or phosphatidylinositol 3,4,5‐trisphosphate. PI4,5P2 interacts with hundreds of different effector proteins. The enormous diversity of PI4,5P2 effector proteins and the spatio‐temporal control of PI4,5P2 generation allow PI4,5P2 signaling to control a broad spectrum of cellular functions. PI4,5P2 is synthesized by phosphatidylinositol phosphate kinases (...) (PIPKs). The array of PIPKs in cells enables their targeting to specific subcellular compartments through interactions with targeting factors that are often PI4,5P2 effectors. These interactions are a mechanism to define spatial and temporal PI4,5P2 synthesis and the specificity of PI4,5P2 signaling. In turn, the regulation of PI4,5P2 effectors at specific cellular compartments has implications for understanding how PI4,5P2 controls cellular processes and its role in diseases. (shrink)

Probability as understood today, namely as a quantitative notion expressible by means of a function ranging in the interval between 0–1, took shape in the mid-17th century, and presents both a mathematical and a philosophical aspect. Of these two sides, the second is by far the most controversial, and fuels a heated debate, still ongoing. After a short historical sketch of the birth and developments of probability, its major interpretations are outlined, by referring to the work of their most prominent (...) representatives. The final section addresses the question of whether any of such interpretations can presently be considered predominant, which is answered in the negative. (shrink)

Building on two nonproblematic claims, I argue for a qualified endorsement of Hume's intuition that there must be a time-difference between cause and effect. Those claims are: (i) that the statement 'A caused B' is meaningful only if we have a criterion for saying 'A' and 'B' refer to distinct events; and (ii) that an adequate view of what it is to be an event must illuminate the enterprise of seeking to establish a singular causal statement. Specifically, I argue there (...) must be a time-difference when cause and effect are modifications of the same physical object. (shrink)

B. F. Skinner has argued that those who are serious about ending war, pollution, etc., must face the fact that the received methods of changing behavior have proved ineffective. According to Skinner, we must replace 'weak' methods of control such as control via praise and blame and control via Rousseau's 'natural contingencies of things' with Skinner's 'strong' methods of control. It is argued that Skinner's case for the continued ineffectiveness of such methods of control rests on the unargued assumption that (...) we are stuck with the highly centralized forms of social organization that characterize present-day advanced societies, forms that place barriers between man and man and between man and nature. Drawing on the anarchist tradition in political thought, it is argued that a radical decentralization — which cannot be dismissed as Utopian — would bring a new effectiveness to what Skinner dismisses as 'weak' forms of control. (shrink)

This volume offers an introduction to consciousness research within philosophy, psychology and neuroscience, from a philosophical perspective and with an emphasis on the history of ideas and core concepts. The book begins by examining consciousness as a modern mystery. Thereafter, the book introduces philosophy of mind and the mind-body problem, and proceeds to explore psychological, philosophical and neuroscientific approaches to mind and consciousness. The book then presents a discussion of mysterianist views of consciousness in response to what can be perceived (...) as insurmountable scientific challenges to the problem of consciousness. As a response to mysterianist views, the next chapters examine radical approaches to rethinking the problem of consciousness, including externalist approaches. The final two chapters present the author's personal view of the problem of consciousness. Consciousness remains a mystery for contemporary science-a mystery raising many questions. Why does consciousness persist as a mystery? Are we humans not intelligent enough to solve the riddle of consciousness? If we can solve this mystery, what would it take? What research would we need to conduct? Moreover, the mystery of consciousness prompts the larger question of how well the cognitive sciences have actually advanced our understanding of ourselves as human beings. After all, consciousness is not just a minor part of our existence. Without consciousness, we would not be human beings at all. This book aims to increase the accessibility of major ideas in the field of consciousness research and to inspire readers to contribute to the ongoing discussion of the place of consciousness in nature. (shrink)

We identify the locally finite graphs that are quantifier-eliminable and their first order theories in the signature of distance predicates. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

B. F. Skinner argues in Beyond Freedom and Dignity (New York 1971) that only his theory of man is compatible with a ?scientific? approach to human behavior. I argue that Skinner's entirely open?ended view of man is inadequate for his own purposes in that it leaves no room for the claim that certain value judgments are universally valid, something I argue Skinner is committed to despite an explicit avowal in one place of cultural relativism. I then go on to show (...) that a modification of Skinner's theory of man which builds on Spinoza's notion of conatus would provide one with a theory?based rationale for universally valid judgments without involving one in a ?non?scientific? approach to human behavior. Specifically, I argue that such a Spinozistic modification would provide one with a theory?based guarantee that man will not evolve in such a way that a truly scientific observer would deem a totalitarian state good. (shrink)

: The coloniality of power is understood by Anibal Quijano as at the constituting crux of the global capitalist system of power. What is characteristic of global, Eurocentered, capitalist power is that it is organized around two axes that Quijano terms "the coloniality of power" and "modernity." The coloniality of power introduces the basic and universal social classification of the population of the planet in terms of the idea of race, a replacing of relations of superiority and inferiority established through (...) domination with naturalized understandings of inferiority and superiority. In this essay, Lugones introduces a systemic understanding of gender constituted by colonial/modernity in terms of multiple relations of power. This gender system has a light and a dark side that depict relations, and beings in relation as deeply different and thus as calling for very different patterns of violent abuse. Lugones argues that gender itself is a colonial introduction, a violent introduction consistently and contemporarily used to destroy peoples, cosmologies, and communities as the building ground of the "civilized" West. (shrink)

My aim in this paper is to investigate what epistemic role, if any, do appeals to representations play in cognitive neuroscience. I suggest that while at present they seem to play something in between a minimal and a substantive explanatory role, there is reason to believe that representations have a substantial contribution to the construction of neuroscientic explanations of cognitive phenomena.

Dal "disegno su sabbia" delle donne australiane alle terrecotte delle donne del Camerun, dai retablos peruviani agli altari vodou degli immigrati haitiani a New York, dalla "Casa del popolo" del regno di Bandjoun alle "vetrinette" italiane degli anni Sessanta, dai malanggan e dai manufatti annodati dell'Oceania alla topologia dei nodi, dai bologan del Mali alla "Potlatch Collection" rimpatriata nei nuovi musei indigeni del Canada, dalle maschere gelede degli Yoruba alla figura ubiqua e mediatica di Mami Wata, i saggi di questo (...) volume evidenziano le valenze operative dell'arte: sia nell'arena sociale e politica contemporanea, cui appartengono anche le "tradizioni", sia nel campo cognitivo e religioso. A lungo confinata ai soli territori esotici delle culture "primitive" e limitata da un'eccessiva dipendenza dalle categorie interpretative occidentali, la riflessione antropologica sull'arte e sull'estetica trova oggi un nuovo respiro teorico, e un nuovo fascino. (shrink)

In this Chapter, Maria Kronfeldner discusses whether psychological essentialism is a necessary part of dehumanization. This involves different elements of essentialism, and a narrow and a broad way of conceptualizing psychological essentialism, the first akin to natural kind thinking, the second based on entitativity. She first presents authors that have connected essentialism with dehumanization. She then introduces the error theory of psychological essentialism regarding the category of the human, and distinguishes different elements of psychological essentialism. On that basis, Kronfeldner (...) connects historical, socio-psychological, and philosophical insights in order to show that although essentialism can act as a catalyst for dehumanization, it is not necessary for it. Examples relate to dehumanization in the context of colonialism and evolutionary thinking, to the history of dehumanizing women from Aristotle to 19th-century craniology, and to contemporary self-dehumanization and ‘lesser mind’ attribution. (shrink)

The coloniality of power is understood by Anibal Quijano as at the constituting crux of the global capitalist system of power. What is characteristic of global, Eurocentered, capitalist power is that it is organized around two axes that Quijano terms “the coloniality of power” and “modernity.” The coloniality of power introduces the basic and universal social classification of the population of the planet in terms of the idea of race, a replacing of relations of superiority and inferiority established through domination (...) with naturalized understandings of inferiority and superiority. In this essay, Lugones introduces a systemic understanding of gender constituted by colonial/modernity in terms of multiple relations of power. This gender system has a light and a dark side that depict relations, and beings in relation as deeply different and thus as calling for very different patterns of violent abuse. Lugones argues that gender itself is a colonial introduction, a violent introduction consistently and contemporarily used to destroy peoples, cosmologies, and communities as the building ground of the “civilized” West. (shrink)