Explaining the causal mechanisms that contribute to autism spectrum disorder occurrence remains a conundrum in developmental medicine, neuroscience, and child psychiatry. Recent research has resulted in agreement on behavioral definitions and their underlying cognitive processes, early diagnosis and standardized assessments, evidence-based interventions, systems-level approaches to neurobiology, and identification of genetic variants and their interaction with epigenetic and environmental factors. However, an explanatory model of autism causation remains elusive.Perhaps..

In this paper we present a set of good practices in the design of a security-centric architecture for a Communication Channel that can be used to secure a Loosely-Coupled distributed platform, over unreliable communication mediums. The proposed practices are derived from designing a complete architecture that is modular and designed to support principles of Service Oriented Architecture (SOA) and the common functional requirements of a wide range of applications, including cybersecurity, smart power grids and industrial Internet of Things (IoT). The (...) architecture was developed and implemented as part of the BIECO project, and is based around open standards such as Open Platform Communications United Architecture (OPC-UA). The key feature of the architecture is that it enables secure asynchronous near-real-time communication between a large number of nodes in a multimodal setup, without the need of any Service to know its place within the tool-chain. Based on our experience with building this system and based on the good results obtained, we are presenting a list of lessons learnt, recommendations for better communication channel modules within loosely coupled distributed systems. (shrink)