The paper describes the conceptual models used to understand the processes determining plant growth rates in response to environmental changes. A series of experiments and growth models were used at three organizational levels: the specific plant organs, the whole plant and the plant canopy. The energy conversion efficiency and the total plant carbon balance were first examined. The carbon partitioning amongst the plant parts was then studied. The energy conversion efficiency is generally understood. In modelling carbon partitioning it was first (...) necessary to establish the carbon demand for each plant organ. The carbon partitioned amongst plant organs was then calculated in two ways. The first one based on empirical data consisted in defining which organ received the carbon prior to other organs. The second one was based on the relationship between the carbon mass of specific organs and their trophic activity. This hypothesis allowed the optimization of the carbon partitioning in order to maximize the whole plant growth rate. The opportunities to use these theoretical approaches in plant growth modelling are discussed. (shrink)

New concepts may prove necessary to profit from the avalanche of sequence data on the genome, transcriptome, proteome and interactome and to relate this information to cell physiology. Here, we focus on the concept of large activity-based structures, or hyperstructures, in which a variety of types of molecules are brought together to perform a function. We review the evidence for the existence of hyperstructures responsible for the initiation of DNA replication, the sequestration of newly replicated origins of replication, cell division (...) and for metabolism. The processes responsible for hyperstructure formation include changes in enzyme affinities due to metabolite-induction, lipid-protein affinities, elevated local concentrations of proteins and their binding sites on DNA and RNA, and transertion. Experimental techniques exist that can be used to study hyperstructures and we review some of the ones less familiar to biologists. Finally, we speculate on how a variety of in silico approaches involving cellular automata and multi-agent systems could be combined to develop new concepts in the form of an Integrated cell (I-cell) which would undergo selection for growth and survival in a world of artificial microbiology. (shrink)

The ventricular pressure profile is characteristic of the cardiac contraction progress and is useful to evaluate the cardiac performance. In this contribution, a tissue-level electromechanical model of the left ventricle is proposed, to assist the interpretation of left ventricular pressure waveforms. The left ventricle has been modeled as an ellipsoid composed of twelve mechano-hydraulic sub-systems. The asynchronous contraction of these twelve myocardial segments has been represented in order to reproduce a realistic pressure profiles. To take into account the different energy (...) domains involved, the tissue-level scale and to facilitate the building of a modular model, multiple formalisms have been used: Bond Graph formalism for the mechano-hydraulic aspects and cellular automata for the electrical activation. An experimental protocol has been defined to acquire ventricular pressure signals from three pigs, with different afterload conditions. Evolutionary Algorithms have been used to identify the model parameters in order to minimize the error between experimental and simulated ventricular pressure signals. Simulation results show that the model is able to reproduce experimental ventricular pressure. In addition, electro-mechanical activation times have been determined in the identification process. For example, the maximum electrical activation time is reached, respectively, 96.5, 139.3 and 131.5 ms for the first, second, and third pigs. These preliminary results are encouraging for the application of the model on non-invasive data like ECG, arterial pressure or myocardial strain. (shrink)

The ventricular pressure profile is characteristic of the cardiac contraction progress and is useful to evaluate the cardiac performance. In this contribution, a tissue-level electromechanical model of the left ventricle is proposed, to assist the interpretation of left ventricular pressure waveforms. The left ventricle has been modeled as an ellipsoid composed of twelve mechano-hydraulic sub-systems. The asynchronous contraction of these twelve myocardial segments has been represented in order to reproduce a realistic pressure profiles. To take into account the different energy (...) domains involved, the tissue-level scale and to facilitate the building of a modular model, multiple formalisms have been used: Bond Graph formalism for the mechano-hydraulic aspects and cellular automata for the electrical activation. An experimental protocol has been defined to acquire ventricular pressure signals from three pigs, with different afterload conditions. Evolutionary Algorithms have been used to identify the model parameters in order to minimize the error between experimental and simulated ventricular pressure signals. Simulation results show that the model is able to reproduce experimental ventricular pressure. In addition, electro-mechanical activation times have been determined in the identification process. For example, the maximum electrical activation time is reached, respectively, 96.5, 139.3 and 131.5 ms for the first, second, and third pigs. These preliminary results are encouraging for the application of the model on non-invasive data like ECG, arterial pressure or myocardial strain. (shrink)

Le chevalier Louis de Jaucourt (1704-1780), principal auteur de l'Encyclopédie avec plus de dix-sept mille articles, est une figure marquante des Lumières, qui néanmoins reste largement méconnue. Ce livre collectif explore différents aspects de l'oeuvre du chevalier, dans l'Encyclopédie et au-delà. Il analyse la richesse et la diversité de sa pensée qui paraît à travers son éclectisme philosophique ou son écriture par emprunts, dans son propos médical, son travail d'historien, de biographe, de juriste, de critique d'art, ou encore d'encyclopédiste (...) et d'éditeur. Dans tous les cas, l'étude des articles de Jaucourt révèle une pensée stimulante, à la fois représentative de l'Encyclopédie et originale par plusieurs de ses traits. (shrink)

D. N. Rodowick _Gilles Deleuze's Time Machine_ Durham and London: Duke University Press, 1997 ISBN: 0822319705 280 pp.

When it was first published in French in 1980, The Ordinary Man of Cinema signaled a shift from the French film criticism of the 1960s to a new breed of film philosophy that disregarded the semiotics and post-structuralism of the preceding decades. Schefer describes the schizophrenic subjectivity the cinema offers us: the film as a work projected without memory, viewed by (and thereby lived by) a subject scarred and shaped by memory. The Ordinary Man of Cinema delineates the phenomenology of (...) movie-going and the fleeting, impalpable zone in which an individuals personal memory confronts the cinemas ideological images to create a new way of thinking. It is also a book replete with mummies and vampires, tyrants and prostitutes, murderers and freaksfigures that are fundamental to Schefers conception of the cinema, because the worlds that cinema traverses (our worlds, interior and exterior) are worlds of pain, unconscious desire, decay, repressed violence, and the endless mystery of the body. Fear and pleasure breed monsters, and such are what Schefers emblematic "ordinary man" seeks and encounters when engaging in the disordering of the ordinary that the movie theater offers him. Among other things, Schefer considers "The Gods" in 31 brief essays on film stills and "The Criminal Life" with reflections on spectatorship and autobiography. While Schefers book has long been standard reading in French film scholarship, until now it has been something of a missing link to the field (and more broadly, French theory) in English. It is one of the building blocks of more widely known and read translations of Gilles Deleuze (who cited this book as an influence on his own cinema books) and Jacques Rancière. (shrink)

Provides a short introduction to Kant, emphasizing Kant's own view of his philosophy. Deleuze offers an overview of the whole of Kant's critical philosophy.

Book review of Jean-Louis Schefer's The Ordinary Man of Cinema (2016) with particular attention to Schefer's conception of affect and its influence on Deleuze.

Theory, theoretical practice, and theoretical formation -- On theoretical work -- Philosophy and the spontaneous philosophy of the scientists (1967) -- Lenin and philosophy -- Is it simple to be a Marxist in philosophy? -- The transformation of philosophy -- Marxism today.

Considered one of the most important works of one of France's foremost philosophers, and long-awaited in English, "The Logic Of Sense" is an essay in literary and psychoanalytic theory, and philosophy, and helps to illuminate such works as "Anti-Oedipus".

Praised for its rare combination of scholarly rigor and imaginative interpretation, _Nietzsche and Philosophy_ has long been recognized as one of the most important analyses of Nietzsche. It is also one of the best introductions to Deleuze's thought, establishing many of his central philosophical positions. In _Nietzsche and Philosophy_, Deleuze identifies and explores three crucial concepts in Nietzschean thought-multiplicity, becoming, and affirmation-and clarifies Nietzsche's views regarding the will to power, eternal return, nihilism, and difference. For Deleuze, Nietzsche challenged conventional philosophical (...) ideas and provided a means of escape from Hegel's dialectical thinking, which had come to dominate French philosophy. He also offered a path toward a politics of difference. In this new edition, Michael Hardt's foreword examines the profound influence of Deleuze's provocative interpretations on the study of Nietzsche, which opened a whole new avenue in postwar thought. (shrink)

Until recently, cognitive science focused on such mental functions as problem solving, grammar, and pattern-the functions in which the human mind most closely resembles a computer. But humans are more than computers: we invent new meanings, imagine wildly, and even have ideas that have never existed before. Today the cutting edge of cognitive science addresses precisely these mysterious, creative aspects of the mind.The Way We Think is a landmark analysis of the imaginative nature of the mind. Conceptual blending is already (...) widely known in research laboratories throughout the world; this book, written to be accessible to both lay readers and interested scientists, is its definitive statement. Gilles Fauconnier and Mark Turner show that conceptual blending is the root of the cognitively modern human mind, and that conceptual blends themselves are continually combined and reblended to create the rich mental fabric in which we live.The Way We Think shows how this blending operates; how it is affected by (and gives rise to) language, identity, culture, and invention; and how we imagine what could be and what might have been. The result is a bold and exciting new view of how the mind works. (shrink)

"Le projet le plus général de Nietzsche consiste en ceci : introduire en philosophie les concepts de sens et de valeur. Nietzsche n'a jamais caché que la philosophie du sens et des valeurs dut être une critique. Que Kant n'ait pas mené la vraie critique, parce qu'il n'a pas su en poser le problème en termes de valeurs, tel est même un des mobiles principaux de l'oeuvre de Nietzsche". Cette analyse rigoureuse et critique de la philosophie de Nietzsche est une (...) lumineuse introduction à l'oeuvre d'un philosophe trop souvent réduit au nihilisme, à la volonté de puissance et l'image du surhomme. Gilles Deleuze remarque que "la philosophie moderne présente des amalgames, qui témoignent de sa vigueur et de sa vivacité, mais qui comportent aussi des dangers pour l'esprit" et que la force du projet philosophique de Nietzsche dans le "dépassement" de la métaphysique est "de dénoncer toutes les mystifications qui trouvent dans la dialectique un dernier refuge. La philosophie de Nietzsche a une grande portée polémique". (shrink)

This book, which presents Spinoza's main ideas in dictionary form, has as its subject the opposition between ethics and morality, and the link between ethical ...

This paper critically examines the materialism that Gilles Deleuze espouses in his oeuvre to the benefit of educational theory. In Difference and Repetition, he presented transcendental empiricism by underwriting Kant with realism (Deleuze, 1994). Later, in Capitalism & Schizophrenia I & II that were co-written with Félix Guattari (1984, 1988) and that they named Anti-Oedipus and A Thousand Plateaus, Deleuze's philosophical approach is realigned into what I term here as transcendental materialism, and latterly as immanent materialism; that I claim effectively (...) eliminate phenomenology as perceptual input. This essay takes this transformation seriously as a way of understanding educational data, research and practices. The proposition that is central to this paper is that transcendental and immanent materialism give us a means of dealing with educational phenomena without the interference of perception or a stable category of experience, by connecting data with theory and circumventing subjectification. It is argued that this proposition has important consequences for educational research, and the construction of educational arguments that will be illustrated in this essay. Deleuze's debt to French Marxism and in particular to the work of Louis Althusser are also recognised through this writing. (shrink)

Treating mathematical science as a distinct cultural entity subject to environmental factors which influence its evolution, the author examines the creation and development of its major concepts since early times.

At last available in paperback, this book anticipates and explains the post-structuralist turn to empiricism. Presenting a challenging reading of David Hume's philosophy, the work is invaluable for understanding the progress of Deleuze's thought.

Examines the philosophy of Henri Bergson, explains his concepts of duration, memory, and elan vital, and discusses the influence of science on Bergson.

"Gill's and Ryan's Parmenides is, simply, superb: the Introduction, more than a hundred pages long, is transparently clear, takes the reader meticulously through the arguments, avoids perverseness, and still manages to make sense of the dialogue as a whole; there is a fine selective bibliography; and those parts of the translation I have looked at in detail suggest that it too is very good indeed." --Christopher Rowe, _Phronesis_.

Empathy remains poorly understood, under-theorized, and subject to conflicting and opportunistic uses. Its systematic role in human experience has not been analyzed and interpreted from top to bottom. In this book, the author attempts to provide such an analysis in the philosophical traditions of hermeneutics, phenomenology, analytic philosophy of language, and psychoanalysis. applying his interpretation of empathy to the philosophical issues of intentionality, the emotions, and the checkered transformations of empathy itself. In doing so the author aims to rescue empathy (...) from the margins of intelligibility and reveal its central role in our understanding of the emotions, the integrity of our relations with others, and human community (“intersubjectivity”). -/- The work draws on both the Anglo-American (“analytic”) tradition of ordinary language philosophy and the continental ones of phenomenology and hermeneutics. This work follows the movement of empathy from the periphery of ethics, aesthetics, and theory of mind to a key place in establishing and maintaining the integrity and emotional equilibrium of dynamic interrelations with other individuals. Beginning with the philosophical infrastructure of the hermeneutics of empathy, this work thoroughly explains the complex architecture of empathy, tracing it downward through the levels of authentic human interrelations, empathy with unexpressed emotions, the empathic penetrability of cognitively impenetrable affect, the first-ever intentional analysis of both the empathizer and the “empathasand” in interrelation, and the hermeneutic infrastructure. The consequences of empathy are exposed in the context of the emotions, cognitive impenetrability, empathy and altruism, and the intentionality of empathy as accessed through language and story telling. Drawing on the multi-method approach of hermeneutics, phenomenology, and story telling, this work demonstrates that empathy forms the foundation for community in ways not clearly appreciated in the on-going debate. In a bootstrap operation that is guided by Heidegger’s call for a “special hermeneutic of empathy,” this work achieves a delicate balancing act of unpacking the rich intellectual traditions from which empathy - the phenomenon itself, not the concept - emerged historically. The result is an exposure of the deep structure of empathy as a fundamentally human capability for creating possibilities of community and human relations. (shrink)

Mental Spaces is the classic introduction to the study of mental spaces and conceptual projection, as revealed through the structure and use of language. It examines in detail the dynamic construction of connected domains as discourse unfolds. The discovery of mental space organization has modified our conception of language and thought: powerful and uniform accounts of superficially disparate phenomena have become available in the areas of reference, presupposition projection, counterfactual and analogical reasoning, metaphor and metonymy, and time and aspect in (...) discourse. The present work lays the foundation for this research. It uncovers simple and general principles that lie behind the awesome complexity of everyday logic. (shrink)

A milestone in the development of post-war Marxist thought.

This brilliant exposition of the critique of identity is a classic in contemporary philosophy and one of Deleuze's most important works. Of fundamental importance to literary critics and philosophers,Difference and Repetition develops two central concepts—pure difference and complex repetition&mdasha;and shows how the two concepts are related. While difference implies divergence and decentering, repetition is associated with displacement and disguising. Central in initiating the shift in French thought away from Hegel and Marx toward Nietzsche and Freud, _Difference and Repetition_ moves deftly (...) to establish a fundamental critique of Western metaphysics. (shrink)

French journalist Claire Parnet's famous dialogues with Gilles Deleuze offer an intimate portrait of the philosopher's life and thought. Conversational in tone, their engaging discussions delve deeply into Deleuze's philosophical background and development, the major concepts that shaped his work, and the essence of some of his famous relationships, especially his long collaboration with the philosopher Félix Guattari. Deleuze reconsiders Spinoza, empiricism, and the stoics alongside literature, psychoanalysis, and politics. He returns to the notions of minor literature, deterritorialization, the critical (...) and clinical, and begins a nascent study of cinema. New to this edition is Deleuze's essay "Pericles and Verdi," which reflects on politics and historical materialism in the work of the influential French philosopher François Châtelet. An enduring record of Deleuze's unique personality and profound contributions to culture and philosophy, _Dialogues II_ is a highly personable account of the evolution of one of the greatest critics and theorists of the twentieth century. (shrink)

‘A rare and remarkable book.’ Times Literary SupplementGilles Deleuze (1925-1995) was Professor of Philosophy at the University of Paris VIII. He is a key figure in poststructuralism, and one of the most influential philosophers of the twentieth century.F\’elix Guattari (1930-1992) was a psychoanalyst at the la Borde Clinic, as well as being a major social theorist and radical activist. A Thousand Plateaus is part of Deleuze and Guattari’s landmark philosophical project, Capitalism and Schizophrenia - a project that still sets the (...) terms of contemporary philosophical debate. A Thousand Plateaus provides a compelling analysis of social phenomena and offers fresh alternatives for thinking about philosophy and culture. Its radical perspective provides a toolbox for ‘nomadic thought’ and has had a galvanizing influence on today’s anti-capitalist movement.Translated by Brian Massumi>. (shrink)

Imagining being someone else from the inside is something relatively easy to do. In Williams (Imagination and the self, problems of the self: philosophical papers, p 26–45, 1973), for instance, one finds Williams’s famous imaginative scenario consisting in imagining being Napoleon from the inside at the battle of Austerlitz. However, providing an adequate analysis for imagination reports like “(1) Williams imagines being Napoleon (from the inside)” is no easy task, because the logical form of such imagination report is controversial. Following (...) Vendler (Revue de Métaphysique et de Morale 84(2):161–173, 1979), the logical form of statements “X imagines F-ing” typically involve a _PRO_ construction. Furthermore, it is generally acknowledged following Chierchia (Semant Contextual Exp 11:1–31, 1989) that _PRO_ constructions require a _de se_ reading. Consequently, (1) is argued to be an instance of _de se_ imagination (this is the “genuine _de se_” analysis of (1)). Yet, (1) is also crucially about Napoleon and, as forcefully argued for in Williams (Imagination and the self, problems of the self: philosophical papers, p 26–45, 1973), it is not even clear that it is about Williams. So (1) cannot be an instance of _de se_ imagination in the standard sense, because Williams does not self-ascribe the semantic content of the imagining episode (this is the “quasi-_de se_” analysis of (1)). In this paper, I vindicate the genuine _de se_ analysis, based on some new data involving nested imaginings. I then investigate some consequences of the view, which, I argue, are not available to the quasi-_de se_ theorists, including what the view says about failed imaginings. (shrink)

The need for quantitative measurement represents a unifying bond that links all the physical, biological, and social sciences. Measurements of such disparate phenomena as subatomic masses, uncertainty, information, and human values share common features whose explication is central to the achievement of foundational work in any particular mathematical science as well as for the development of a coherent philosophy of science. This book presents a theory of measurement, one that is "abstract" in that it is concerned with highly general axiomatizations (...) of empirical and qualitative settings and how these can be represented quantitatively. It was inspired by, and represents a generalization and extension of, the last major research work in this field, Foundations of Measurement Vol. I, by Krantz, Luce, Suppes, and Tversky published in 1971. (shrink)