The sites of tightest adhesion that form between cells and substrate surfaces in tissue culture are termed focal contacts. The external faces of focal contacts include specific receptors, belonging to the integrin family of proteins, for fibronectin and vitronectin, two common components of extracellular matrices. On the internal (cytoplasmic) side of focal contacts, several proteins, including talin and vinculin, mediate interactions with the actin filament bundles of the cytoskeleton. The changes that occur in focal contacts as a result of viral (...) transformation are discussed. (shrink)

An online survey of 654 Australians found that the NP seniors is associated with positive personal characteristics of health and well-being such as ‘like to travel’, ‘lead an involved and active life’, ‘are vibrant and full of purpose’. Older people is also associated with positive characteristics, but somewhat less so than seniors and more socially oriented. Older people are seen to ‘benefit the workforce through their experience’, ‘have wisdom and can always be turned to for advice’, ‘play an important role (...) in their extended family’s life’. By contrast, the characteristics of those typically referred to by the elderly are negative in that the referents are incompetent or impose a burden on society, cf. ‘are frail and fall more often’, ‘are often victims of mental and physical abuse’, ‘are unable to look after themselves and depend on others for help’. The referents of old people and oldies have no particular set of characteristics assigned to them; perhaps that is why they only figure in the one characteristic ‘are tight-fisted with money’ that itself is not strongly associated with any one of the five NPs. (shrink)

Encountering Aborigines: A Case Study: Anthropology and the Australian Aboriginal details the concerns in contemporary anthropological research of aboriginal Australians.

This article elaborates on Wolfgang Schulze’s keynote speech of the same title at the 26th LIPP Symposium in Munich in 2019. It is based on the slides from his talk and various teaching materials, of which some figures have been translated from German to English before their inclusion in this article. While this article’s foundation rests on Schulze’s theories and research, we have done our best to build upon his work; direct quotes and key concepts of his will be cited (...) throughout the text. Schulze intended to write this article himself, but after his unexpected passing in early 2020, we decided to offer this contribution on his behalf.Research on taboo is widely spread across diverse academic disciplines that each attribute slightly, yet noticeably, different meanings to the concept. This article proposes an all-encompassing definition applicable to all socio-cultural contexts. To arrive at this comprehensive understanding, we first briefly survey the history oftabooand its linguistic study. Then, we present a formal and functional typology of circumnavigating taboos, taking into account the concepts ofmanaandnoaas proposed by Schulze (2019: 13, 15, 16). While the specific social restrictions resulting from tabooed relations vary from community to community, the purpose of taboo remains the same: social stability, protection and sustainability. Linguistic taboos contribute to these social functions by restricting the use of certain linguistic signs in certain situations. Such constraints necessitate strategies for avoiding taboo, including articulation shift, lexical substitution and the emergence of special languages, detailed here. (shrink)

Focal adhesions disassemble during mitosis, but surprisingly little is known about how these structures respond to other phases of the cell cycle. Three recent papers reveal unexpected results as they examine adhesions through the cell cycle. A biphasic response is detected where focal adhesions grow during S phase before disassembly begins early in G2. In M phase, activated integrins at the tips of retraction fibers anchor mitotic cells, but these adhesions lack the defining components of focal adhesions, such as talin, (...) paxillin, and zyxin. Re‐examining cell‐matrix adhesion reveals reticular adhesions, a new class of adhesion. These αVβ5 integrin‐mediated adhesions also lack conventional focal adhesion components and anchor mitotic cells to the extracellular matrix. As reviewed here, these studies present insight into how adhesion complexes vary through the cell cycle, and how unconventional adhesions maintain attachment during mitosis while providing spatial memory to guide daughter cell re‐spreading after cell division. (shrink)