So much for the Aesthetic. We can now proceed to the Analytic, the philosophical importance of which is much greater. Kant's main contentions in this part of his work can be summed up in; two propositions: human understanding contains certain a priori concepts, and on these are based certain non-empirical principles; these concepts are only general concepts of a phenomenal object, and therefore the principles in question are only prescriptive to sense-experience. As has already been said, interest in the first (...) proposition has distracted attention from the fact that the important thing Kant has to say is contained in the second. (shrink)

There is now a general consensus amongst philosophers in the values in science literature that values necessarily play a role in core areas of scientific inquiry. We argue that attention should now be turned from debating the value-free ideal to delineating legitimate from illegitimate influences of values in science, a project we dub “The New Demarcation Problem.” First, we review past attempts to demarcate the uses of values and propose a categorization of the strategies by where they seek to draw (...) legitimacy from. Next, we propose a set of desiderata for what we take to be a satisfactory solution and present a case study where conflicting sets of values clearly impinge on science, but where the legitimacy of their influence is ambiguous. We use these desiderata and the case study to illustrate what we take to be the strengths and weaknesses of current strategies. To be clear, our goal is not to answer the question we pose, but to articulate a framework within which a solution can be judged. (shrink)

Industry is a major source of funding for scientific research. There is also a growing concern for how it corrupts researchers faced with conflicts of interest. As such, the debate has focused on whether researchers have maintained their integrity. In this article we draw on both the history of medicine and formal modeling to argue that given methodological diversity and a merit-based system, industry funding can bias a community without corrupting any particular individual. We close by considering a policy solution (...) that may seem to promote unbiased inquiry but that actually exacerbates the problem without additional restrictions. (shrink)

In recent years the social nature of scientific inquiry has generated considerable interest. We examine the effect of an epistemically impure agent on a community of honest truth seekers. Extending a formal model of network epistemology pioneered by Zollman, we conclude that an intransigently biased agent prevents the community from ever converging to the truth. We explore two solutions to this problem, including a novel procedure for endogenous network formation in which agents choose whom to trust. We contend that our (...) model nicely captures aspects of current problems in medical research and gesture at some morals for medical epistemology more generally. (shrink)

There are some philosophical questions that can be answered without attention to the social context in which evidence is produced and distributed.ing away from social context is an excellent way to ignore messy details and lay bare the underlying structure of the limits of inference. Idealization is entirely appropriate when one is essentially asking: In the best of all possible worlds, what am I entitled to infer? Yet, philosophers’ concerns often go beyond this domain. As an example I examine the (...) debate on mechanistic evidence and then reevaluate a canonical case study in this debate. I show that for the assessment of actual evidence, produced in a world that is far from ideal, omission of the social aspects of medical epistemology leads philosophers to draw the wrong lessons from cases they take as paradigmatic cases for their views. I close by arguing that social epistemology provides an avenue to incorporate these complications and provides the necessary framework to understand medical evidence. (shrink)

Private companies provide by far the most funding for scientific research and development. Nevertheless, relatively little attention has been paid to the dynamics of industry‐funded research by philosophers of science. This paper addresses this gap by providing an overview of the major strengths and weaknesses of industry research funding, together with the existing recommendations for addressing the weaknesses. It is designed to provide a starting point for future philosophical work that explores the features of industry‐funded research, avenues for addressing concerns, (...) and strategies for making research funded by the private sector as fruitful as possible. (shrink)

We examine arguments regarding the use of mechanistic evidence in assessing treatment efficacy and find that advocates and critics of EBM+ have largely been talking past each other due to a difference in focus. We explore aducanumab for the treatment of Alzheimer’s disease as a case which may speak to the role of EBM+ in pharmaceutical regulation. The case suggests the debate may be more fruitful if philosophers confine debates to particular domains of medicine and weigh in prospectively instead of (...) relying on historical cases where outcomes are known and which are susceptible to hindsight bias. (shrink)

ABSTRACT This study investigated the effect of conspiracy ideation, moral disengagement, and intolerance of uncertainty on compliance with the anti-SARS-COV-2 social distancing rules and two other facets of people’s reactions toward the coronavirus crisis. A convenience sample of 245 Romanians completed an online survey in March 2020. Results indicate that conspiracy ideation is associated with lower assessments of virus risk and lower compliance with the confinement measures. Moral disengagement had a parallel effect of undermining personal compliance to the social distancing (...) regulations, highlighting the need to define social distancing as morally relevant and prevent individual justifications for noncompliance. (shrink)

We examine arguments for and against the use of mechanistic evidence in assessing treatment efficacy and find that advocates of EBM+ and their critics have largely been talking past each other due to difference in focus. We explore aducanumab for the treatment of Alzheimer’s disease as a case which may speak to the role of EBM+ in pharmaceutical regulation. The case suggests the debate may be more fruitful if philosophers confine debates to particular domains of medical science and weigh in (...) prospectively instead of relying on historical cases where outcomes are known and which are susceptible to hindsight bias. (shrink)

“Female sexual dysfunction” is the type of contested disease that has sparked concern about the role of the pharmaceutical industry in medical science. Many policies have been proposed to manage industry influence without carefully evaluating whether the proposed policies would be successful. We consider a proposal for incorporating citizen stakeholders into scientific research and show, via a detailed case study of the pharmaceutical regulation of flibanserin, that such programs can be co-opted. In closing, we use Holman’s asymmetric arms race (...) framework as a tool for evaluating policies in industry-funded science. (shrink)

Agent-based models have played a prominent role in recent debates about the merits of democracy. In particular, the formal model of Lu Hong and Scott Page and the associated “diversity trumps ability” result has typically been seen to support the epistemic virtues of democracy over epistocracy (i.e., governance by experts). In this paper we first identify the modeling choices embodied in the original formal model and then critique the application of the Hong-Page results to philosophical debates on the relative merits (...) of democracy. In particular we argue that the “best-performing agents” in Hong-Page model should not be interpreted as experts. We next explore a closely related model in which best-performing agents are more plausibly seen as experts and show that the diversity trumps ability result fails to hold. However, with changes in other parameters (such as the deliberation dynamic) the diversity trumps ability result is restored. The sensitivity of this result to parameter choices illustrates the complexity of the link between formal modeling and more general philosophical claims; we use this debate as a platform for a more general discussion of when and how agent-based models can contribute to philosophical discussions. (shrink)

Arguments that medical decision making should rely on a variety of evidence often begin from the claim that meta-analysis has been shown to be problematic. In this paper, I first examine Stegenga’s argument that meta-analysis requires multiple decisions and thus fails to provide an objective ground for medical decision making. Next, I examine three arguments from social epistemologists that contend that meta-analyses are systematically biased in ways not appreciated by standard epistemology. In most cases I show that critiques of meta-analysis (...) fail to account for the full range of meta-analytic procedures. In the remainder of cases, I argue that the critiques identify problems that do not uniquely cut against meta-analysis. I close by suggesting one reason why it may be pragmatically rational to violate the principle of total evidence and by outlining the criteria for a successful argument against meta-analysis. A set of criteria I contend remain unmet. (shrink)

This paper describes one possible origin point for fraudulent behavior within the American pharmaceutical industry. We argue that during the late nineteenth century therapeutic reformers sought to promote both laboratory science and increasingly systematized forms of clinical experiment as a new basis for therapeutic knowledge. This process was intertwined with a transformation in the ethical framework in which medical science took place, one in which monopoly status was replaced by clinical utility as the primary arbiter of pharmaceutical legitimacy. This new (...) framework fundamentally altered the set of epistemic virtues—a phrase we draw from the philosophical field of virtue epistemology—considered necessary to conduct reliable scientific inquiry regarding drugs. In doing so, it also made possible new forms of fraud in which newly emergent epistemic virtues were violated. To make this argument, we focus on the efforts of Francis E. Stewart and George S. Davis of Parke, Davis & Company. Therapeutic reformers within the pharmaceutical industry, such as Stewart and Davis, were an important part of the broader normative and epistemic transformation we describe in that they sought to promote laboratory science and systematized clinical trials toward the twin goals of improving pharmaceutical science and promoting their own commercial interests. Yet, as we suggest, Parke, Davis & Company also serves as an example of a company that violated the very norms that Stewart and Davis helped introduce. We thus seek to describe one possible origin point for the widespread fraudulent practices that now characterize the pharmaceutical industry. We also seek to describe an origin point for why we conceptualize such practices as fraudulent in the first place. (shrink)

This study aimed to investigate the relationships between medical professionals’ empathy and two moral coordinates, moral foundations and moral identity. A sample of 157 physicians and nurses completed an adapted version of the Jefferson Scale of Empathy, addressing three dimensions of empathy: compassionate care, perspective taking, and the cognitive dimension of empathy; the Moral Identity Questionnaire, addressing two facets of the importance of moral standards, Moral Self and Moral Integrity; and the Moral Foundations Questionnaire. We found specific patterns of associations (...) between the three dimensions of empathy, moral identity, and moral foundations. Moral self was a significant predictor of all the dimensions of empathy while moral integrity was also significantly related to compassionate care and purity to perspective taking. Health professionals with more than five years of work experience also emerged as lower in compassionate care. Their adherence to moral standards and the importance of moral values should be further enhanced in education as their moral identity can contribute to more empathic behaviors toward patients. (shrink)

Stephen John has recently suggested that the ethics of communication yields important insights as to how values should be incorporated into science. In particular, he examines cases of “wishful speaking” in which a scientific actor endorses unreliable conclusions in order to obtain the consequences of the listener treating the results as credible. He concludes that what is wrong in these cases is that the speaker surreptitiously relies on values not accepted by the hearer, violating what he terms “the value-apt ideal”. (...) I expand on this view by integrating into it Miranda Fricker’s account of testimonial injustice. I find testimonial injustice can arise in a manner unanticipated by Fricker, specifically that a credibility excess given to a speaker typically reduces the ability of others in the epistemic community to transmit knowledge, a phenomenon I term “collateral epistemic injustice”. I argue that this possibility entails that receivers have an ethical obligation to assign credibility judiciously. A further consequence of this view is that the value-apt ideal is insufficient. Because audience members have an obligation to assign credibility judiciously, a speaker cannot merely rely on shared values, they must also be open about the extent to which their conclusions depend on those values. Thus, both wishful speaking and obscuring the value-dependent nature of a conclusion makes one an unreliable source of information. Accordingly, other community members have an ethical obligation to ignore a speaker that frequently engages in either. (shrink)

A critical interrogation of elements of Hobbes's political and natural philosophy and its capacity to enrich our understanding of the natural of democratic life.

The standard philosophical definition of placebos offered by Grünbaum is incompatible with Cartwright’s conception of randomized clinical trials. I offer a modified account of placebos that respects this role and clarifies why many current medical trials fail to warrant the conclusions they are typically seen as yielding. I then consider recent changes to guidelines for reporting medical trials and show that pessimism over parsing out the cause of “unblinding” is premature. Specifically, using a trial of antidepressants, I show how more (...) sophisticated statistical analyses can parse out the source of such effects and serve as an alternative to placebo control. (shrink)

As some see it, an impasse has been reached on the mind- body problem between mainstream physicalism and mainstream dualism. So lately another view has been gaining popularity, a view that might be called the 'Russellian theory of mind' (RTM) since it is inspired by some ideas once put forth by Bertrand Russell. Most versions of RTM are panpsychist, but there is at least one version that rejects panpsychism and styles itself as physicalism, and neutral monism is also a possibility. (...) In this paper I will attempt to sort out these different versions with a view to determining which, if any, have a chance of breaking the perceived impasse. The unsurprising conclusion will be that there are a lot of challenges ahead for the RTM theorist. The surprising conclusion will be that it's not clear that pan- psychist RTM holds an advantage over the other versions in this regard. (shrink)

Anyone who is a color eliminativist‐i.e., believes that the physical world is colorless‐must explain how our sense experience of color can be so systematically illusory. As it turns out, it is difficult to do this without committing oneself to dualism. In this paper I explore the options available to the color eliminativist in this regard, and argue that his/her prospects are more promising, though still far from certain, if s/he adopts the position that sense experience is strictly intentional.

Private companies provide by far the most funding for scientific research and development. Nevertheless, relatively little attention has been paid to the dynamics of industry‐funded research by philosophers of science. This paper addresses this gap by providing an overview of the major strengths and weaknesses of industry research funding, together with the existing recommendations for addressing the weaknesses. It is designed to provide a starting point for future philosophical work that explores the features of industry‐funded research, avenues for addressing concerns, (...) and strategies for making research funded by the private sector as fruitful as possible. (shrink)

This article suggests that the philosophical contributions of the French democratic theorist Miguel Abensour offer a unique model for the practice of the history of political thought. Under the influence of the first generation of Frankfurt School critical theory, Abensour can be seen as applying a method of thinking in constellations to the study of historical texts, the critical rearrangement of conceptual elements drawn from the latter generating new dialectical images that reveal something previously obscured about the object of investigation. (...) The history of political thought on this model is less about the recuperation of a definite textual intelligibility than the revelation of social and political alterity. (shrink)

This book constitutes one of the most important contributions to recent Kant scholarship. In it, one of the pre-eminent interpreters of Kant, Henry Allison, offers a comprehensive, systematic, and philosophically astute account of all aspects of Kant's views on aesthetics. The first part of the book analyses Kant's conception of reflective judgment and its connections with both empirical knowledge and judgments of taste. The second and third parts treat two questions that Allison insists must be kept distinct: the normativity (...) of pure judgments of taste, and the moral and systematic significance of taste. The fourth part considers two important topics often neglected in the study of Kant's aesthetics: his conceptions of fine art, and the sublime. (shrink)

Modern observations based on general relativity indicate that the spatial geometry of the expanding, large-scale Universe is very nearly Euclidean. This basic empirical fact is at the core of the so-called “flatness problem”, which is widely perceived to be a major outstanding problem of modern cosmology and as such forms one of the prime motivations behind inflationary models. An inspection of the literature and some further critical reflection however quickly reveals that the typical formulation of this putative problem is fraught (...) with questionable arguments and misconceptions and that it is moreover imperative to distinguish between different varieties of problem. It is shown that the observational fact that the large-scale Universe is so nearly flat is ultimately no more puzzling than similar “anthropic coincidences”, such as the specific values of the gravitational and electromagnetic coupling constants. In particular, there is no fine-tuning problem in connection to flatness of the kind usually argued for. The arguments regarding flatness and particle horizons typically found in cosmological discourses in fact address a mere single issue underlying the standard FLRW cosmologies, namely the extreme improbability of these models with respect to any “reasonable measure” on the “space of all spacetimes”. This issue may be expressed in different ways and a phase space formulation, due to Penrose, is presented here. A horizon problem only arises when additional assumptions—which are usually kept implicit and at any rate seem rather speculative—are made. (shrink)

Recent scholarship on the political thought of Niccolò Machiavelli has demonstrated the extent to which the latter's republicanism is of a populist type, and a potentially important resource for contemporary democratic theory. Although work has been produced on the constitutional form of the Machiavellian republic, less effort has been made to articulate the theoretical assumptions upon which the advocacy of such a republic is ethically grounded. Here, I attempt to locate the democratic ethical imperative in the affirmation of a fundamental (...) human difference. Influenced by the Epicurean tradition, Machiavelli's natural philosophy considers material entities as absolute singularities lacking internal teleological direction, their movement the productive result of contingent encounters. One cannot assume a natural or pre-social identity of desire between persons. Democracy is the ethically preferred regime because it is the one that is capable of facilitating the expression of this human uniqueness. (shrink)

Not so long ago, the idea that analytic philosophers would be taking panpsychism seriously would have been hard to believe. That is because in its early, logical positivist, stage, the analytic movement earned the reputation of being militantly anti-metaphysical. But analytic philosophy has come a long way since the heyday of logical positivism; and, in fact, the dialectic of recent debates on the mind–body problem among analytic philosophers has pushed many of them in the direction of panpsychism. In this paper, (...) I want to explain how this has come about and take a look at some of the versions of panpsychism that have emerged. This will involve running through a quick history of debates on the mind–body problem since about 1960, focusing on how panpsychism has been proposed as a promising, though not unproblematic, way of breaking an apparent impasse that has emerged between more standard physicalist and dualist theories of mind. Along the way, I will also have occasion to comment on the prospects of panpsychism as a respectable scientific theory and how a number of scientists stand on this. (shrink)

Public discussions of political and social issues are often characterized by deep and persistent polarization. In social psychology, it’s standard to treat belief polarization as the product of epistemic irrationality. In contrast, we argue that the persistent disagreement that grounds political and social polarization can be produced by epistemically rational agents, when those agents have limited cognitive resources. Using an agent-based model of group deliberation, we show that groups of deliberating agents using coherence-based strategies for managing their limited resources tend (...) to polarize into different subgroups. We argue that using that strategy is epistemically rational for limited agents. So even though group polarization looks like it must be the product of human irrationality, polarization can be the result of fully rational deliberation with natural human limitations. (shrink)

A popular defense of physicalist theories of consciousness against anti-physicalist arguments invokes the existence of ‘phenomenal concepts’. These are concepts that designate conscious experiences from a first person perspective, and hence differ from physicalistic concepts; but not in a way that precludes co-referentiality with them. On one version of this strategy phenomenal concepts are seen as (1) type demonstratives that have (2) no mode of presentation. However, 2 is possible without 1-call this the ‘bare recognitional concept’ view-and I will argue (...) that this avoids certain recent criticisms while retaining the virtue of finessing the ‘mode of presentation’ problem for phenomenal concepts. But construing phenomenal concepts this way seems to not do justice to the phenomenology of conscious experience. In this paper I examine whether or not this impression can be borne out by a good argument. As it turns out, it is harder to do so than one might think. It can be done, but it involves somewhat more convoluted reasoning than one might have supposed necessary. Having shown that, I will end with a few brief remarks on what my argument means for attempts to preserve a physicalist account of consciousness. (shrink)

Thinking Radical Democracy is an introduction to nine key political thinkers who contributed to the emergence of radical democratic thought in post-war French political theory: Hannah Arendt, Maurice Merleau-Ponty, Pierre Clastres, Claude Lefort, Cornelius Castoriadis, Guy Debord, Jacques Rancière, Étienne Balibar, and Miguel Abensour. The essays in this collection connect these writers through their shared contribution to the idea that division and difference in politics can be perceived as productive, creative, and fundamentally democratic. The questions they raise regarding equality and (...) emancipation in a democratic society will be of interest to those studying social and political thought or democratic activist movements like the Occupy movements and Idle No More. --Provided by publisher. (shrink)

Frank Jackson formulated his knowledge argument as an argument for dualism. In this paper I show how the argument can be modified to also establish the irreducibility of the secondary qualities to the properties of physical theory, and ultimately "secondary quality eliminativism"- the view that the secondary qualities are physically uninstantiated.

Few books have so firmly established their place in American literature as The Education of Henry Adams. When it was first published in 1918, it became an instant bestseller and went on to win the Pulitzer Prize. More than eighty years later, in an age of self-reflection and exhaustive memoirs, The Education still stands as perhaps the greatest American autobiography. The son of a diplomat, the grandson and great-grandson of two American presidents, a man of extraordinary gifts and learning (...) in his own right, Henry Adams recounts his life from his birth in 1838 and upbringing as a Boston Brahmin, through the Civil War, the nation's industrial expansion, and its emergence as a world power. In the process, he gives us a brilliant history of a changing country as well as a thoughtful, humane, often tender exploration of himself. From the original publisher, this edition of The Education of Henry Adams, newly introduced by Donald Hall, celebrates and honors this classic work on what it means to be an American. (shrink)

This article examines the political anthropological work of Pierre Clastres in light of the emergence of the subfield of comparative political theory. In particular, it argues that Clastres’ recons...

The Hong and Page ‘diversity trumps ability’ result has been used to argue for the more general claim that a diverse set of agents is epistemically superior to a comparable group of experts. Here we extend Hong and Page’s model to landscapes of different degrees of randomness and demonstrate the sensitivity of the ‘diversity trumps ability’ result. This analysis offers a more nuanced picture of how diversity, ability, and expertise may relate. Although models of this sort can indeed be suggestive (...) for diversity policies, we advise against interpreting such results overly broadly. (shrink)

In the present exploratory study, our primary aim was to explore whether knowledge about the fast-fashion industry's harmful effects would significantly impact participants' shopping intentions. Using an experimental approach, we created a virtual clothing shop and allowed participants to win, through a raffle, the contents of their shopping carts. Participants in the experimental group watched a video about the adverse environmental consequences of the fast-fashion industry. In contrast, in the control group, we used a neutral video describing various technical marketing (...) strategies. In the experimental condition, participants chose more eco-friendly products) compared to the control. However, there were no significant differences between the two groups in terms of fast-fashion consumption behaviors, i.e., the choices of buying fast-fashion items. We also found several significant associations between participants' general concern for the environment, consideration of future consequences, civic moral disengagement, and consumption behaviors. Results are discussed concerning their practical implications for sustainable citizenship participation and sustainable education. (shrink)

The present study explored how Romanian women perceive in-vitro fertilization, surrogacy, and adoption as alternative pathways to traditional parenthood. Previous studies suggested that both...

We were interested in exploring the associations and effects of experimental language (i.e., native – L1, or foreign – L2), dilemma type (i.e., personal – D1 or impersonal – D2), the digital device participants used (i.e., PC/laptop or smartphone), along with gender and age in sacrificial COVID-19 and non-COVID moral dilemmas. We performed two studies involving 522 participants aged 18 to 69 in April 2020. In Study 1, we found no significant associations between the dilemma type and the digital device. (...) However, most participants chose to sacrifice an older COVID-19 patient in a critical medical condition to prioritize rescuing similar, younger patients (i.e., 45-year-old males). Results also suggested that male and younger participants were more likely to choose the utilitarian option when the sacrificial dilemma was presented in French. In study 2 (i.e., non-COVID-19), participants made significantly more utilitarian choices in the personal dilemmas presented in French. Results are discussed concerning the SARS-CoV-2 pandemic context and its emotional impact on moral judgment. (shrink)