Biological individuality is a notoriously thorny topic for biologists and philosophers of biology. In this paper we argue that biological individuality presents multiple, interconnected questions for biologists and philosophers that together form a problem agenda. Using a case study of an interdisciplinary research group in ecology, behavioral and evolutionary biology, we claim that a debate on biological individuality that seeks to account for diverse practices in the biological sciences should be broadened to include and give prominence to questions about uniqueness (...) and temporality. We show that broadening the problem agenda of biological individuality draws attention to underrecognized philosophical issues and discussions and thereby organizes and enriches the existing debate. (shrink)

Biological individuality is without a doubt a key concept in philosophy of biology. Questions around the individuality of organisms, species, and biological systems can be traced throughout the philosophy of biology since the discipline’s inception, not to mention the sustained attention they have received in biology and philosophy more broadly. It’s high time the topic got its own Cambridge Element. McConwell’s Biological Individuality falls short of an authoritative overview of the debate on biological individuality. However, it sends a welcome message (...) to new and seasoned scholars to reorient the debate towards practically and politically relevant themes. (shrink)

German; one contribution each in English and French.

German; one contribution each in English and French.

Die begriffliche Unterscheidung von Natur und Kultur sowie die Deutung von Kultur als einer zweiten Natur des Menschen sind von systematischer Bedeutung für die Kulturtheorie Georg Simmels. Um den Nebensinn der zweiten Natur als einer bloßen Gewohnheit, die man auch ablegen könnte, nicht zu evozieren, verwendet Simmel selbst den Ausdruck zweite Natur nicht, bewegt sich aber in einer bestimmten Theorietradition, die diesen auf Cicero zurückgehenden Ausdruck programmatisch adaptiert. Von einer Theorie des objektiven Geistes in der Nachfolge von Moritz Lazarus ausgehend, (...) entwickelt Simmel eine Kulturphilosophie, in deren Zentrum die Frage nach dem Verhältnis zwischen dem individuellen Lebensvollzug des Einzelnen und den ihn umgebenden und herausfordernden kulturellen Objektivationen steht. (shrink)

In this article, we develop the concept of Transparency by Design that serves as practical guidance in helping promote the beneficial functions of transparency while mitigating its challenges in automated-decision making environments. With the rise of artificial intelligence and the ability of AI systems to make automated and self-learned decisions, a call for transparency of how such systems reach decisions has echoed within academic and policy circles. The term transparency, however, relates to multiple concepts, fulfills many functions, and holds different (...) promises that struggle to be realized in concrete applications. Indeed, the complexity of transparency for ADM shows tension between transparency as a normative ideal and its translation to practical application. To address this tension, we first conduct a review of transparency, analyzing its challenges and limitations concerning automated decision-making practices. We then look at the lessons learned from the development of Privacy by Design, as a basis for developing the Transparency by Design principles. Finally, we propose a set of nine principles to cover relevant contextual, technical, informational, and stakeholder-sensitive considerations. Transparency by Design is a model that helps organizations design transparent AI systems, by integrating these principles in a step-by-step manner and as an ex-ante value, not as an afterthought. (shrink)

Poetisierende Musikbeschreibungen werden von der Wissenschaft, von Musikern und Konzertbesuchern heute mehr belächelt als ernst genommen. Durch das Ansprechen von Einbildungskraft und Gefühl haben sie aber eine Unmittelbarkeit, die der kompositionstechnischen Analyse in der Regel fehlt. Die Wurzeln einer metaphorischen Musikbeschreibung um die Wende zum 19. Jahrhundert sind dabei gleichermaßen historisch wie systematisch zu fassen. Zahlreiche Zitate aus den Fachzeitschriften bis zur Jahrhundertmitte dokumentieren die Herausbildung eines festumrissenen Bildervorrats, um musikalische Eindrücke zur Sprache zu bringen. Der kreative Umgang mit Beschreibungskonventionen (...) ist für die Musikkritiken von E.T.A. Hoffmann, Adolf Bernhard Marx, Ludwig Rellstab und vor allem Robert Schumann kennzeichnend. (shrink)

What constitutes our number concept? What makes it possible for us to employ numbers the way we do; which mental faculties contribute to our grasp of numbers? What do we share with other species, and what is specific to humans? How does our language faculty come into the picture? This 2003 book addresses these questions and discusses the relationship between numerical thinking and the human language faculty, providing psychological, linguistic and philosophical perspectives on number, its evolution and its development in (...) children. Heike Wiese argues that language as a human faculty plays a crucial role in the emergence of systematic numerical thinking. She characterises number sequences as powerful and highly flexible mental tools that are unique to humans and shows that it is language that enables us to go beyond the perception of numerosity and to develop such mental tools. (shrink)

The article explores the underlying reasons for patients’ self‐perception of being a burden (SPB) in family settings, including its impact on relationships when wishes to die (WTD) are expressed. In a prospective, interview‐based study of WTD in patients with advanced cancer and non‐cancer disease (organ failure, degenerative neurological disease, and frailty) SPB was an important emerging theme. In a sub‐analysis we examined (a) the facets of SPB, (b) correlations between SPB and WTD, and (c) SPB as a relational phenomenon. We (...) analyzed 248 interviews with 62 patients, their family caregivers, and professionals using grounded theory and interpretive phenomenological analysis. SPB appeared as important empathic concern in care situations. Patients expressed many sorts of concerns for others, but also perceived an altered self‐understanding that did not meet mutual expectations within relationships. In SPB associated with WTD three constellations were found: (a) WTD to unburden others; (b) patients decided against hastening death to prevent being a further burden to others (in these cases, the SPB counteracted the wish to die); and (c) both wishes for and against dying were sustained by SPB. These patients often felt paralyzed and suffered deeply. Family caregivers felt emotionally touched by SPB and tried to unburden patients by caring and compassion. We concluded that the impact of SPB on a WTD and the various meanings the facets of SPB have in balancing relationships need to be worked out individually. An early palliative and narrative approach is warranted. (shrink)

We argue for a perspective on bilingual heritage speakers as native speakers of both their languages and present results from a large-scale, cross-linguistic study that took such a perspective and approached bilinguals and monolinguals on equal grounds. We targeted comparable language use in bilingual and monolingual speakers, crucially covering broader repertoires than just formal language. A main database was the open-access RUEG corpus, which covers comparable informal vs. formal and spoken vs. written productions by adolescent and adult bilinguals with heritage-Greek, (...) -Russian, and -Turkish in Germany and the United States and with heritage-German in the United States, and matching data from monolinguals in Germany, the United States, Greece, Russia, and Turkey. Our main results lie in three areas. We found non-canonical patterns not only in bilingual, but also in monolingual speakers, including patterns that have so far been considered absent from native grammars, in domains of morphology, syntax, intonation, and pragmatics. We found a degree of lexical and morphosyntactic inter-speaker variability in monolinguals that was sometimes higher than that of bilinguals, further challenging the model of the streamlined native speaker. In majority language use, non-canonical patterns were dominant in spoken and/or informal registers, and this was true for monolinguals and bilinguals. In some cases, bilingual speakers were leading quantitatively. In heritage settings where the language was not part of formal schooling, we found tendencies of register leveling, presumably due to the fact that speakers had limited access to formal registers of the heritage language. Our findings thus indicate possible quantitative differences and different register distributions rather than distinct grammatical patterns in bilingual and monolingual speakers. This supports the integration of heritage speakers into the native-speaker continuum. Approaching heritage speakers from this perspective helps us to better understand the empirical data and can shed light on language variation and change in native grammars. Furthermore, our findings for monolinguals lead us to reconsider the state-of-the art on majority languages, given recurring evidence for non-canonical patterns that deviate from what has been assumed in the literature so far, and might have been attributed to bilingualism had we not included informal and spoken registers in monolinguals and bilinguals alike. (shrink)

We prove the consistency result from the title. By forcing we construct a model of g = ℵ l , b = cf(Sym(ω)) = ℵ 2.

Drawing on data from a comparative ethnographic study on media usage in transnational families, this paper contributes to a reappraisal of polymedia theory. Two main theoretical assumptions are reconsidered. First, it is demonstrated why the equal availability assumption has to be revised in light of the complex interactions between the corporeal, communicative and social mobilities which together constitute transnational migration. Second, it is argued that the techno-socially accomplished co-presence in transnational families depends more on the creative appropriation and combination of (...) different media channels and communication forms than on the choice between them. In order to empirically investigate the specific needs for, and forms of co-presence in families, the concept of ‘registers of presence’ is proposed. It allows us to understand in detail in what ways and in which constellations transnational families create togetherness with the help of communication technologies. (shrink)

Despite decades of management and conservation efforts, we have seen only limited success in rebuilding marine life and restoring ocean ecosystems from human-inflicted damage on a global scale. I suggest that we need to harness both our emotional and rational sides to create a more powerful movement to heal the ocean and rebuild its abundance and diversity. Love and compassion fuel our desire and urge for change and provide a compass that can guide our actions. Science and knowledge provide ways (...) for collecting and interpreting data and information that can enhance our understanding and support our decisions and actions. Combining our emotional and rational sides can inspire our thinking and transform our actions in new, creative ways. In order to affect wide-ranging and long-lasting change, love and knowledge need to work together to transform our collective relationship with the ocean. (shrink)

Nachdem der Zusammenhang zwischen Sprache und Emotion in der Linguistik lange Zeit vernachlässigt wurde, erhält diese Frage seit etwa 25 Jahren so hohe Aufmerksamkeit, dass von einem 'emotional turn' gesprochen werden kann. Der vorliegende Band dient als Zusammenfassung des aktuellen Forschungsstandes zu diesem komplexen Thema. Berücksichtigt werden Erkenntnisse aus verschiedenen Teildisziplinen, z.B. Semiotik, Lexikologie, Pragmatik, Kognitive Linguistik und Textlinguistik. Im methodischen Teil wird gezeigt, wie eine emotionslinguistische Analyse emotive Strukturen in Texten offenlegen kann, wobei die vorgeschlagene Methode leicht an verschiedene (...) Fragestellungen angepasst werden kann. Die empirische Überprüfung ergibt einen Vergleich von drei sehr unterschiedlichen Textkorpora: Untersucht werden Briefe von Franz Kafka als Beispiel für einen Individualstil, Nachrichtenartikel von verschiedenen Online-Plattformen als Beispiel für Medientexte und die Kommunikationsform Twitter als Beispiel für Online-Kommunikation. Forschende, Lehrende und Studierende finden hier sowohl einen umfassenden Überblick über theoretische Grundlagen als auch Anregungen für die Anwendung in der eigenen Forschung und Lehre. (shrink)

The respiration of oxygen, while essential to aerobic organisms for the generation of energy, leads to the formation of reactive oxygen intermediates (ROIs) as harmful byproducts. ROIs damage nucleic acids, lipids and proteins. Therefore, protective mechanisms against elevated intracellular ROI levels, referred to as oxidative stress, have evolved. These include the activation of transcription factors which elevate the expression of protective enzymes. Eukaryotic cells have also evolved the ability to specifically generate ROIs are used as second messengers to activate gene (...) expression. Here we will discuss both prokaryotic and eukaryotic transcription factors that respond to ROIs. In addition, transcription factors will be described that are activated by either exposure to antioxidants, which reduce the intracellular ROI concentration, or by hypoxia, the absence of oxygen. (shrink)

This paper provides an introduction to ethical issues arising in children's research that takes place in school-settings. It addresses three main areas of ethical concern: the informed consent process, confidentiality, and harm and benefit. Informed consent in school settings is characterized by the involvement of multiple stakeholders, including not just researchers, parents and individual children but also school principals, teachers and the children's peer group. The added complexity of the setting has implications for the management of the informed consent process, (...) including the decision at what point and in which manner each stakeholder group needs to be involved in the process. The presence and divergent roles of these multiple stakeholders in the school setting also have implications for addressing issues of confidentiality, especially due to the group setting in which participants take part in the research and role expectations within school settings. Harm and benefit in school-based research are of a non-physical nature; relevant areas of concern relate primarily to the potential for psychological and social harm, realistic presentation of likely benefits from research and the issue of rewards for research participation. (shrink)

It is consistent that each union of many families in the Baire space which are not finitely dominating is not dominating. In particular, it is consistent that for each nonprincipal ultrafilter , the cofinality of the reduced ultrapower is greater than . The model is constructed by oracle chain condition forcing, to which we give a self-contained introduction.

The volume provides an overview of the origins of early medieval aristocratic literature. Although there are regional, linguistic and formal differences, one can observe a number of similarities. Oral literature disseminates a range of themes that are shared by narratives in most parts of the continent. The authors address these similarities in Roman, Nordic, Anglo-Saxon and Germanic literature and use different methodologies to explain them.

tRNA nucleotidyltransferase adds the invariant CCA‐terminus to the tRNA 3′‐end, a central step in tRNA maturation. This CCA‐adding enzyme is a specialized RNA polymerase that synthesizes the CCA sequence at high fidelity in all kingdoms of life. Recently, an additional function of this enzyme was identified, where it generates a specific degradation tag on structurally unstable tRNAs. This tag consists of an additional repeat of the CCA triplet, leading to a 3′‐terminal CCACCA sequence. In order to explain how the enzyme (...) catalyzes this extended polymerization reaction, Kuhn et al. solved a series of co‐crystal structures of the CCA‐adding enzyme from Archaeoglobus fulgidus in complex with different tRNA substrates. They show that the enzyme forces a bound unstable tRNA to refold the acceptor stem for a second round of CCA‐addition, while stable transcripts are robust enough to resist this isomerization. In this review, we discuss how the CCA‐adding enzyme uses a simple yet very elegant way to scrutinize its substrates for sufficient structural stability and, consequently, functionality. (shrink)

Long description: Welche Triebkräfte und Möglichkeitsräume gesellschaftlicher Veränderung verbinden sich mit den Dynamiken des modernen Kapitalismus? Tino Heims breit angelegte Studie zielt auf die Überwindung analytischer Defizite der jüngsten Kapitalismusdebatte. In einer theoriesystematischen Verknüpfung und gegenstandsbezogenen Weiterentwicklung der Analyseraster von Marx, Foucault und Bourdieu - die auch als Kritik dominanter Rezeptionslinien antritt - werden zentrale kapitalistische Funktionslogiken und Krisendynamiken ebenso prägnant analysiert wie historische Transformationen konkreter Modi kapitalistischer Vergesellschaftung. Damit wird zugleich ein Beitrag zur Neubestimmung einer analytisch-kritischen Sozialwissenschaft jenseits normativer (...) Sozialkritik geleistet. (shrink)

The article takes Helmuth Plessner’s Political Anthropology from 1931 as a postfoundationalist theory of society avant la lettre - which is very similar to the later works of Claude Lefort, Ernesto Laclau, and Chantal Mouffe. Or, the article takes Plessner’s essay as an ‘ontology’ of the Political. After introducing remarks on the historical debates, in which Plessner aimed to intervene, his theory of the Political is reconstructed, within the three categories of ‘unfathomability’, of the constitutive outside, and of the vulnerability (...) of the human body. In a third and last step, Plessner’s most central and most problematic category for the Political - the ‘popular existence’ - is discussed: The ‘people’ is made visible as being a key notion of postfoundational theories of modern democracy, for it is - beneath the ‘Individual’ - one of the imaginary foundations, one of the foundational outsides of a democratically instituted collective. (shrink)

In this note we argue that Lars von Trier’s movie Dogville can be viewed as an illustration of a simple economy where one agent has only her body as initial endowment. The movie illustrates some interesting comparative statics of equilibrium allocations. It shows how life would be like in a world where, in the absence of constitutional or legal constraints, economic forces reign freely and raises some fundamental issues of voluntary exchange versus force that apply to a number of contentious (...) issues in public debate. JEL codes: A20, D30, D51, D63, F13. Keywords: Dogville, general equilibrium, welfare theorems, comparative statics, international trade, child labor, prostitution, economics education. (shrink)

Fields for Innovative Future Research in History of Science – A Historian of Technology's Perspective. The observations at hand present a historian of technology's perspective and sketch three fields for innovative future research: (past) ‘futures’ and future scenarios in themselves; the challenges as imposed by recent developments in science, technology, and society (e.g. digitization, climate change); and the twisting and flipping of established perspectives (e.g. by focusing on ‘failed’ or ‘old’ science and technology and their declension). Moreover, historians of science, (...) technology, and medicine should participate in emerging transdisciplinary fields such as Environmental Humanities. (shrink)

To ensure ethical employee behavior, companies often utilize several forms of mostly one-way communication such as codes of conduct. The extent to which these efforts, in addition to informing about the company stance on ethics, are able to positively influence behavior is disputed. In contrast, research on business ethics communication and behavior indicates a relatively clear, positive link between open workplace dialogue about ethical issues and ethical conduct. In this article, I therefore address the question: What influences employee attitudes to (...) talking openly about ethical issues? Answers are proposed on the basis of focus group interviews with staff at the Denmark and Brazil affiliates of the global healthcare company Novo Nordisk. It was found that interest in discussing ethical issues was influenced by two main factors: employee conceptualizations of business ethics and the level of inter-collegial trust, credibility, and confidence. In this article, by examining these phenomena, I aim at providing insight that can both inform scholars in these fields as well as help managers in their attempts to promote open workplace dialogue about ethical issues. (shrink)

We show: The procedure mentioned in the title is often impossible. It requires at least an inner model with a measurable cardinal. The consistency strength of changing b and d from a regular κ to some regular δ < κ is a measurable of Mitchell order δ. There is an application to Cichon's diagram.

We show that it is independent whether club $\kappa $ -Miller forcing preserves $\kappa ^{++}$. We show that under $\kappa ^{ \kappa $, club $\kappa $ -Miller forcing collapses $\kappa ^{<\kappa }$ to $\kappa $. Answering a question by Brendle, Brooke-Taylor, Friedman and Montoya, we show that the iteration of ultrafilter $\kappa $ -Miller forcing does not have the Laver property.

In this commentary, the core features of the Irish Protection of Life During Pregnancy Act 2013 are outlined. This legislation provides, for the first time in the history of the Irish state, a framework for the provision of lawful abortion in Ireland. The paper will explain the background to the legislation, discuss its main features, and reflect on the likely impact that it will have on the availability of abortion in Ireland.

Direct to consumer genetic testing has given rise to much controversy, especially in relation to testing for health diagnostic purposes. This paper will consider whether consumers' use of DTC genetic testing should be understood as predominantly recreational. It will be argued that recreational testing can encompass all information domains, including most kinds of predictive health risk information. In relation to recreational testing the potential identity implications for the consumer become a significant concern, more so than the risks more traditionally associated (...) with genetic testing. It will be concluded that while the DTC genetic testing sector is beset by numerous problems and an increase in consumers' genetic literacy is highly desirable, consumers' engagement with DTC genetic testing may be less problematic than sometimes assumed. (shrink)

We show: There are pairs of universes V1V2 and there is a notion of forcing PV1 such that the change mentioned in the title occurs when going from V1[G] to V2[G] for a P-generic filter G over V2. We use forcing iterations with partial memories. Moreover, we implement highly transitive automorphism groups into the forcing orders.

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 41.1 (2003) 123-124 [Access article in PDF] Andrew Barker. Scientific Method in Ptolemy's Harmonics. New York: Cambridge University Press, 2001. Pp. viii + 281. Cloth, $69.95. Ptolemy's Harmonics is an important source not only for the history of music, but also for the history and philosophy of science. Two recent monographs, by J. Solomon, and A. Barker, now provide a basis for a (...) more widespread discussion of this much neglected work. Barker focuses on the part that is concerned with musical science proper (I, 1-III, 3), and more specifically on the scientific method it displays.Barker uses an analysis of Ptolemy's programmatic statements in I, 1/2, as a key to a reading of Ptolemy's treatise. His exposition has the format of a commentary, with special emphasis on the methodologically relevant passages. For the most part, he follows the order of Ptolemy's text closely, providing historical background information in excursus form. One needs to read a complete text of Ptolemy's treatise along with Barker's exposition in order to understand some of his arguments. It is preferable to also use Düring's [End Page 123] edition of the Greek text. One is rewarded with a detailed and in-depth analysis of the passages that helps one understand Ptolemy's method in harmonics as it unfolds in his treatise. This is so even if one disagrees with Barker's claims concerning Ptolemy's methodology.These claims are outlined in chapter 2, on the basis of I, 1/2 of the Harmonics. The methodological program Barker filters out of the text remains vague in a number of important respects. One misses, for example, a clear exposition on what will count as a sufficient integration of "empirical and theoretical phases," and on what will count as "empirical." This is a serious drawback, since Barker claims that Ptolemy instantiates a complex scientific methodology with a decisive, fully integrated empiricist trait. The drawback is aggravated by the fact that the already vague terms of the postulated methodology have to be watered down considerably in the subsequent chapters to make them fit with Ptolemy's actual procedures. Ptolemy does not seem to deliver even on the vague terms. One may very well remain unconvinced both by Barker's initial arguments concerning Ptolemy's methodology, and by his attempts to show that Ptolemy's procedure in the Harmonics can count as a satisfactory instantiation. Perhaps Ptolemy's intentions are less ambitious. When he states (5.13 ff. Düring, ed.) that "the aim of the student of harmonics must be to preserve the hupotheseis..., as never in any way conflicting with the perceptions that correspond to most people's estimation," he may just mean that he intends to vindicate an essentially Pythagorean (locally modified) account by showing it does not conflict with the phenomena. In my view, he certainly delivers on this less ambitious program. In fact, it seems to me that the understanding of Ptolemy's argumentative path is impeded by Barker's interpretation of Ptolemy's goal of "saving the hupotheseis" as a commitment to the integration of a genuine empiricist trait.Chapters 7 and 8 give an exposition of Ptolemy's tetrachord divisions. For the reader interested in an evaluation of the theoretical aspect of Ptolemy's scientific method, these are the central chapters of Barker's book. Barker provides a detailed analysis, together with an exposition of the historical and technical information needed for a non-specialist to follow both his and Ptolemy's argument. Barker's analysis reveals inter alia that a considerable part of Ptolemy's theory has no counterpart in the realm of phenomena perceived as musical, and that another part, concerning the single most important division of musical practice, is not justified, and not justifiable, by derivation from the principles. It is difficult to see how Ptolemy's account can nevertheless be viewed as a genuine integration of empirical and theoretical aspects. It appears to be an attempt at showing that an essentially Pythagorean theory... (shrink)

This article’s central aim is to debunk the overly simplified, paradigmatic, and essentialist description of certain types of Muslim sexuality, arguing that such essentialist characterization of Muslims ignores the nonunique social determinants (poverty, education, and sociostructural exclusions) of HIV/aids risk in an increasingly globalized world. To support this argument, we rely on a thematic and comparative analysis. A reoccurring theme in this project is that issues of public health, human rights, justice, and social empowerment are inextricably intertwined. Having established a (...) conceptual framework linking health and human rights, we use a comparative analysis of the cases of Iran, Indonesia, and Bangladesh in an attempt to single out similarities and differences among these cases. All these cases hold a majority Muslim population (at 98%, 86%, and 89%, respectively) and are also representative of the two primary strands of Islam: Shi’a and Sunni. Additionally, each of these states has signed the Declaration of Commitment on HIV/aids and reports the progress of their HIV/aids treatment and prevention efforts to United Nations Program on HIV/aids, the United Nations organization tasked with monitoring and combating the spread of HIV/aids. (shrink)