The Adverse Outcome Pathway (AOP) concept is a knowledge assembly and communication tool to facilitate the transparent translation of mechanistic information into outcomes meaningful to the regulatory assessment of chemicals. The AOP framework and associated knowledgebases (KBs) have received significant attention and use in the regulatory toxicology community. However, it is increasingly apparent that the potential stakeholder community for the AOP concept and AOP KBs is broader than scientists and regulators directly involved in chemical safety assessment. In this paper we (...) identify and describe those stakeholders who currently—or in the future—could benefit from the application of the AOP framework and knowledge to specific problems. We also summarize the challenges faced in implementing pathway-based approaches such as the AOP framework in biological sciences, and provide a series of recommendations to meet critical needs to ensure further progression of the framework as a useful, sustainable and dependable tool supporting assessments of both human health and the environment. Although the AOP concept has the potential to significantly impact the organization and interpretation of biological information in a variety of disciplines/applications, this promise can only be fully realized through the active engagement of, and input from multiple stakeholders, requiring multi-pronged substantive long-term planning and strategies. (shrink)

The words we call slurs are just plain vanilla descriptions like ‘cowboy’ and ‘coat hanger’. They don't semantically convey any disparagement of their referents, whether as content, conventional implicature, presupposition, “coloring” or mode of presentation. What distinguishes 'kraut' and 'German' is metadata rather than meaning: the former is the conventional description for Germans among Germanophobes when they are speaking in that capacity, in the same way 'mad' is the conventional expression that some teenagers use as an intensifier when they’re emphasizing (...) that social identity. That is, racists don’t use slurs because they’re derogatory; slurs are derogatory because they’re the words that racists use. To use a slur is to exploit the Maxim of Manner (or Levinson’s M-Principle) to signal one’s affiliation with a group that has a disparaging attitude towards the slur’s referent. This account is sufficient to explain all the familiar properties of slurs, such as their speaker orientation and “nondetachability,” with no need of additional linguistic mechanisms. It also explains some features of slurs that are rarely if ever explored; for example the variation in tone and strength among the different slurs for a particular group, the existence of words we count as slurs, such as 'redskin', which almost all of their users consider to be respectful, and the curious absence in Standard English of any commonly used slurs—by which I mean words used to express a negative attitude toward an entire group—for Muslims and women. (shrink)

Derided and disregarded by many of his contemporaries, Michel Foucault is now regarded as probably the most influential thinker of the twentieth century, his work is studied across the humanities and social sciences. Reading Foucault, however, can be a challenge, as can writing about him, but in Understanding Foucault, the authors offer an entertaining and informative introduction to his thinking. They cover all the issues Foucault dealt with, including power, knowledge, subjectivity and sexuality and discuss the development of his analysis (...) throughout his work. (shrink)

Abstract:This paper is a further development of two previous pieces of work (Moore 2002, 2005) in which modern virtue ethics, and in particular MacIntyre’s (1985) related notions of “practice” and “institution,” have been explored in the context of business. It first introduces and defines the concept of corporate character and seeks to establish why it is important. It then reviews MacIntyre’s virtues-practice-institution schema and the implications of this at the level of the institution in question—the corporation—and argues that the concept (...) of corporate character follows from, but is a novel development of, MacIntyre’s schema. The paper contrasts corporate character and virtues with the more familiar concepts of corporate culture and values. The constitutive and substantive elements of corporate character, including the essential corporate virtues, are then drawn out and illustrated with reference to the cases explored in Koehn (1998). Finally, the paper acknowledges and counters a specific criticism of this approach. (shrink)

Alvin Plantinga has argued that evolutionary naturalism (the idea that God does not tinker with evolution) undermines its own rationality. Natural selection is concerned with survival and reproduction, and false beliefs conjoined with complementary motivational drives could serve the same aims as true beliefs. Thus, argues Plantinga, if we believe we evolved naturally, we should not think our beliefs are, on average, likely to be true, including our beliefs in evolution and naturalism. I argue herein that our cognitive faculties are (...) less reliable than we often take them to be, that it is theism which has difficulty explaining the nature of our cognition, that much of our knowledge is not passed through biological evolution but learned and transferred through culture, and that the unreliability of our cognition helps explain the usefulness of science. (shrink)

Abstract:This paper is a further development of two previous pieces of work (Moore 2002, 2005) in which modern virtue ethics, and in particular MacIntyre’s (1985) related notions of “practice” and “institution,” have been explored in the context of business. It first introduces and defines the concept of corporate character and seeks to establish why it is important. It then reviews MacIntyre’s virtues-practice-institution schema and the implications of this at the level of the institution in question—the corporation—and argues that the concept (...) of corporate character follows from, but is a novel development of, MacIntyre’s schema. The paper contrasts corporate character and virtues with the more familiar concepts of corporate culture and values. The constitutive and substantive elements of corporate character, including the essential corporate virtues, are then drawn out and illustrated with reference to the cases explored in Koehn (1998). Finally, the paper acknowledges and counters a specific criticism of this approach. (shrink)

Epistemologists have proposed various norms of assertion to explain when a speaker is in an epistemic position to assert a proposition. In this article I propose a distinct necessary condition on assertibility: that a speaker should assert only what she sensitively believes, where a subject's belief is sensitive just in case the subject would not hold it if it were false. I argue that the Sensitivity Rule underwrites simple explanations for three key features of assertibility that pose explanatory challenges to (...) other prominent proposals: the fact that assertibility is open under known entailment, the general impropriety of assertions that a lottery ticket has lost made purely on the basis of the speaker's knowledge of the odds, and the fact that assertibility varies widely with features of the conversational context. I close by considering three distinct roles the Sensitivity Rule might play in the overall theory of assertibility. (shrink)

The concept of integration has garnered increased attention in the past few years, despite a long history of only brief mention. Integration services are offered by therapists, coaches, and other practitioners, or may be self-guided. There are many definitions of psychedelic integration, and the term encompasses a range of practices and techniques. This seems to have led to confusion about what integration is and how it is best practiced. The primary focus of this manuscript is the presentation of the first (...) extensive review and concept analysis of definitions, practices, and models of psychedelic integration. We provide a synthesized definition of integration, synthesized model of integration, and comprehensive summary of integration practices to bring clarity to the subject. (shrink)

This article is a transcript of an interview with Onno Bouwmeester, Professor in the Department of Management and Marketing, Durham University Business School, UK, and the Department of Management and Organization, Vrije Universiteit Amsterdam. The interview focused on his new book Business Ethics and Critical Consultant Jokes. New Research Methods to Study Ethical Transgressions, Springer, 2023.

Contextualism in epistemology has traditionally been understood as the view that “know” functions semantically like an indexical term, encoding different contents in contexts with different epistemic standards. But the indexical hypothesis about “know” faces a range of objections. This article explores an alternative version of contextualism on which “know” is a semantically stable term, and the truth-conditional variability in knowledge claims is a matter of pragmatic enrichment. The central idea is that in contexts with stringent epistemic standards, knowledge claims are (...) narrowed: “know” is used in such contexts to make assertions about particularly demanding types of knowledge. The resulting picture captures all of the intuitive data that motivate contextualism while sidestepping the controversial linguistic thesis at its heart. After developing the view, the article shows in detail how it avoids one influential linguistic objection to traditional contextualism concerning indirect speech reports, and then answers an objection concerning the unavailability of certain types of clarification speeches. (shrink)

For well over a thousand years, countless audiences have taken pleasure in watching unfold the following fearful event:Filled with dread, desperately tossing unchewed grass from its mouth, looking back at the hunting king, a beautiful deer springs into flight to escape a fast-approaching chariot from which repeated arrows fly — one of which will inevitably lodge in the deer’s defenseless body. This is not a scene from “National Geographic” or an episode from some sadly popular TV hunting show. Indeed, this (...) scene has been played out far longer than any current program on America’s “Outdoor Channel,” and it comes to most Westerners from half a world away. Kālidāsa’s The Signet-Ring of Śakuntalā, the most famous poem.. (shrink)

Demonstratives and Indexicals In the philosophy of language, an indexical is any expression whose content varies from one context of use to another. The standard list of indexicals includes pronouns such as “I”, “you”, “he”, “she”, “it”, “this”, “that”, plus adverbs such as “now”, “then”, “today”, “yesterday”, “here”, and “actually”. Other candidates include the tenses … Continue reading Demonstratives and Indexicals →.

A symposium was held at the Centre for Research in the Arts, Social Sciences and Humanities at the University of Cambridge on June 12th 2019, ‘Rethinking Repetition in a Digital Age’, at which Geoff Stead, a leading mobile tech designer, was a keynote speaker. The focus of the Cambridge UK event was on how the potentials of digital technologies—whose harms have received widespread attention—could be redirected for the social good. For Stead, this is precisely what Babbel are doing in (...) their approach to commercial digital language learning. Stead spoke to the idea of reversing our personal relationships to mechanical affordances, and finding empowerment in understanding their designed logics. The transcript of the interview below, made in October 2021, revisits some of the main points he raised at that event. (shrink)

Traditional approaches tend to regard figuration (and by extension, deference in general) as an essentially marked or playful use of language, which is associated with a pronounced stylistic effect. For linguistic purposes, however, there is no reason for assigning a special place to deferred uses that are stylistically notable — the sorts of usages that people sometimes qualify with a phrase like "figuratively speaking." There is no important linguistic difference between using redcoat to refer to a British soldier and using (...) suit to refer to a corporate executive (as in "A couple of suits stopped by to talk about the new products"). What creates the stylistic effect of the latter is not the mechanism that generates it, but the marked background assumptions that license it — here, the playful presupposition that.. (shrink)

Even if our justified beliefs are closed under known entailment, there may still be instances of transmission failure. Transmission failure occurs when P entails Q, but a subject cannot acquire a justified belief that Q by deducing it from P. Paradigm cases of transmission failure involve inferences from mundane beliefs (e.g., that the wall in front of you is red) to the denials of skeptical hypotheses relative to those beliefs (e.g., that the wall in front of you is not white (...) and lit by red lights). According to the Bayesian explanation, transmission failure occurs when (i) the subject’s belief that P is based on E, and (ii) P(Q|E) P(Q). No modifications of the Bayesian explanation are capable of accommodating such cases, so the explanation must be rejected as inadequate. Alternative explanations employing simple subjunctive conditionals are fully capable of capturing all of the paradigm cases, as well as those missed by the Bayesian explanation. (shrink)

The application of machine-learning technologies to medical practice promises to enhance the capabilities of healthcare professionals in the assessment, diagnosis, and treatment, of medical conditions. However, there is growing concern that algorithmic bias may perpetuate or exacerbate existing health inequalities. Hence, it matters that we make precise the different respects in which algorithmic bias can arise in medicine, and also make clear the normative relevance of these different kinds of algorithmic bias for broader questions about justice and fairness in healthcare. (...) In this paper, we provide the building blocks for an account of algorithmic bias and its normative relevance in medicine. (shrink)

This paper argues against the view that trolley cases are of little or no relevance to the ethics of automated vehicles. Four arguments for this view are outlined and rejected: the Not Going to Happen Argument, the Moral Difference Argument, the Impossible Deliberation Argument and the Wrong Question Argument. In making clear where these arguments go wrong, a positive account is developed of how trolley cases can inform the ethics of automated vehicles.

The phenomenon of systematic polysemy offers a fruitful domain for examining the theoretical differences between lexicological and lexicographic approaches to description. We consider here the process that provides for systematic conversion of count to mass nouns in English (a chicken Æ chicken, an oak Æ oak etc.). From the point of view of lexicology, we argue, standard syntactic and pragmatic tests suggest the phenomenon should be described by means of a single unindividuated transfer function that does not distinguish between interpretations (...) (rabbit = "meat" vs. "fur"). From the point of view of lexicography, however, these pragmatically determined"sense precisions" are made part of explicit description via the inclusion of semantic "licenses," a mechanism distinct from lexical rules. (shrink)

Whether it seems that you know something depends in part upon practical factors. When the stakes are low, it can seem to you that you know that p, but when the stakes go up it'll seem to you that you don't. The apparent sensitivity of knowledge to stakes presents a serious challenge to epistemologists who endorse a stable semantics for knowledge attributions and reject the idea that whether you know something depends on how much is at stake. After arguing that (...) previous attempts to meet this challenge fall short, I offer a new solution: the unassertability account. The account starts with the observation that high stakes subjects aren't in an epistemic position to assert. We generally presuppose that knowing is sufficient for epistemically proper assertion, but this presupposition only stands up to scrutiny if we draw a distinction between two notions of epistemic propriety, and we shouldn't expect ordinary speakers to draw it. A subject in a high stakes situation who fails to draw the distinction will be led by the sufficiency claim to treat anything she isn't in a position to assert as something she isn't in a position to know. The sensitivity of epistemically proper assertion to practical factors explains the merely apparent sensitivity of knowledge to stakes. (shrink)

1. Introduction Geoff Cockfield, Ann Firth and John Laurent -/- 2. The Role of Thumos in Adam Smith’s System Lisa Hill -/- 3. Adam Smith’s Treatment of the Greeks in The Theory of Moral Sentiments: The Case of Aristotle Richard Temple-Smith -/- 4. Adam Smith, Religion and the Scottish Enlightenment Pete Clarke -/- 5. The ‘New View’ of Adam Smith and the Development of his Views Over Time James E. Alvey -/- 6. The Moon Before the Dawn: A Seventeenth-Century (...) Precursor of Smith’s The Theory of Moral Sentiments Jack Barbalet -/- 7. Adam Smith’s Moral Philosophy as Ethical Self-formation Ann Firth -/- 8. Science and its Applications in The Theory of Moral Sentiments David Thorpe -/- 9. Adam Smith, Charles Darwin and the Moral Sense John Laurent and Geoff Cockfield. (shrink)

Transitional justice scholars are increasingly concerned with measuring the impact of transitional justice initiatives. Scholars often assume that TJ mechanisms must be properly designed and ordered to achieve lasting effect, but the impact of TJ timing and sequencing has attracted relatively little theoretical or empirical attention. Focusing on Latin America, this article explores variation within the region as to when TJ occurs and the order in which mechanisms are implemented. We utilize qualitative comparative analysis to assess the impact of TJ (...) timing and sequencing on democratic development. We find little evidence for path dependency owing to the chronological order of mechanisms. We do find, however, that amnesties and trials approach a sufficient condition for democratic consolidation in Latin America; trials, however, come closest to being a necessary condition for successful democratic consolidation. (shrink)

Though the term “comparative philosophy” often brings to mind the relatively recent “East-West” encounter, the experience of cultural difference has helped to invigorate philosophical inquiry throughout human history. Doug Berger’s Encounters of Mind highlights this. Over the course of six chapters, Berger follows “the trek of [Vijñānavāda] Buddhism from South to East Asian worlds,” tracing the development of the idea of luminous mind and its centrality to the question of personhood in Chinese Buddhism and Neo-Confucianism. Rather than simply rehash antiquated (...) debates, he reveals nuances of a thriving dialogue that is pertinent to contemporary discussions of personal identity. (shrink)

Philosophy for Children has enabled schools to engage with what is typically thought of as an ‘academic’ discipline and has provided the opportunity to unlock a rich educational experience for children from a diverse range of backgrounds. A wide range of qualitative and quantitative studies have emerged looking at P4C in terms of the development of students at the social, academic and emotional level. However, while there have been many P4C papers that have ‘teacher’ in the title, these are often (...) about teacher training – including ‘hints and tips’ and curriculum development. Relatively few studies have looked at the effect of teaching P4C on teachers themselves. This paper considers how P4C affects teachers, in particular whether teaching P4C has led teachers to develop new pedagogical approaches, different ways of thinking critically and whether it has changed how they engage with their students, colleagues and their school. (shrink)

Rarely in the short history of liberal-democratic government has a primer on basic liberal-democratic values and institutions been more needed than now. Popular discontent, even anger, with democratic governments has grown steadily over the past twenty years. And not since the 1930s have citizens and their elected officials been so baffled about their respective roles in the maintenance of both democratic governments and liberal economies. This book attempts to address this growing need. Especially written as a primer for courses in (...) Philosophy, Politics and Economics (PPE), it has introductory chapters on all three main disciplines. It also has chapters on the rule of law and on three important public-policy areas: Corruption, Climate, and Civil Society. Individual topics discussed include free and fair elections, populism, responsible government, republican and Westminster systems of government, regulated free markets, the Great Recession of 2008, globalization, greenwashing, identity politics, academic freedom, utilitarianism, social contract theory, positive and negative liberty, and the good life. Historically informed, The Ethics and Economics of Liberal Democracies: Foundations for PPE is sure to be of interest to students who are interested in public-policy work, as well as those who are interested in both the theory and practice of democratic government. (shrink)

Recent research in the cognitive science of religion suggests that humans intuitively believe that others survive death. In response to this finding, three cognitive theories have been offered to explain this: the simulation constraint theory (Bering, Citation2002); the imaginative obstacle theory (Nichols, Citation2007); and terror management theory (Pyszczynski, Rothschild, & Abdollahi, 2008). First, I provide a critical analysis of each of these theories. Second, I argue that these theories, while perhaps explaining why one would believe in his own personal immortality, (...) leave an explanatory gap in that they do not explain why one would intuitively attribute survival of death to others. To fill in the gap, I offer a cognitive theory based on offline social reasoning and social embodiment which provides for the belief in an eternal social realm in which the deceased survive—the afterlife. (shrink)

The Thousands of Problems for Theorem Provers (TPTP) World is a well-established infrastructure that supports research, development and deployment of automated theorem proving systems. This paper provides an overview of the logic languages of the TPTP World, from classical first-order form (FOF), through typed FOF, up to typed higher-order form, and beyond to non-classical forms. The logic languages are described in a non-technical way and are illustrated with examples using the TPTP language.

Karl Popper is a philosopher of knowledge and politics, rationality and freedom. His ideas have won acceptance and provoked controversy among an academic as well as a more general audience. This book aims to broaden our understanding of Popper's philosophy. It is one of the few studies to present his work as an evolving "system of ideas", and to take account of the full range of his writings. The book discusses Popper's early philosophy of politics, science and social science, as (...) well as his later philosophy, which offers an evolutionary account of human nature and the growth of knowledge. Contrary to many earlier interpretations, Stokes argues that we should look to Popper's political values to understand the unity of his work and the evolution of his theory of knowledge and general philosophy. The chapters in this book examine Popper's arguments, and offer critical analysis of the achievements and shortcomings of his philosophy. In particular, Stokes considers the problems of rationality, politics and ethics in the context of debates between the Frankfurt School of critical theory and critical rationalism. The book will be of interest to second-year undergraduates and above in the fields of philosophy and critical theory. (shrink)

This book contains 21 essays by leading authorities on aspects of contemporary logic, ranging from foundations of set theory to applications of logic in computing and in the theory of fields. In computer science and mathematics, this gap between foundations and applications is small, as illustrated by essays on the proof theory of non-classical logics, lambda calculus, relating logic programs to inductive definition, and definability in Lindenbaum algebras. Other chapters discuss how to apply model theory to field theory, complex geometry (...) and groups, and how to recover from its automorphism group. (shrink)

This article holds that governmental investments in quantum technologies speak to the imaginable futures of digital sovereignty and digital infrastructures, two major areas of change driven by related technologies like AI and Big Data, among other things, in international law today. Under intense development today for future interpolation into digital systems that they may alter, quantum technologies occupy a sort of liminal position, rooted in existing assemblages of computational technologies while pointing to new horizons for them. The possibilities they raise (...) are neither certain nor determinate, but active investments in them (legal, political and material investments) offer perspective on digital technology-driven influences on an international legal imagination. In contributing to visions of the future that are guiding ambitions for digital sovereignty and digital infrastructures, quantum technologies condition digital technology-driven changes to international law and legal imagination in the present. Privileging observation and description, I adapt and utilize a diffractive method with the aim to discern what emerges out of the interference among the several related things assembled for this article, including material technologies and legal institutions. In conclusion, I observe ambivalent changes to an international legal imagination, changes which promise transformation but appear nonetheless to reproduce current distributions of power and resources. (shrink)

The product/process distinction with regards to “argument” has a longstanding history and foundational role in argumentation theory. I shall argue that, regardless of one’s chosen ontology of arguments, arguments are not the product of some process of arguing. Hence, appeal to the distinction is distorting the very organizational foundations of argumentation theory and should be abandoned.