Background: Only data of published study results are available to the scientific community for further use such as informing future research and synthesis of available evidence. If study results are reported selectively, reporting bias and distortion of summarised estimates of effect or harm of treatments can occur. The publication and citation of results of clinical research conducted in Germany was studied.Methods: The protocols of clinical research projects submitted to the research ethics committee of the University of Freiburg in 2000 were (...) analysed. Published full articles in several databases were searched and investigators contacted. Data on study and publication characteristics were extracted from protocols and corresponding publications.Results: 299 study protocols were included. The most frequent study design was randomised controlled trial , followed by uncontrolled studies , laboratory studies and non-randomised studies . 182 were multicentre studies including 97 international collaborations. 152 of 299 had commercial funding and 46 non-commercial funding. 109 of the 225 completed protocols corresponded to at least one full publication ; the publication rate was 48%. 168 of 210 identified publications were cited in articles indexed in the ISI Web of Science. The median was 11 citations per publication .Conclusions: Results of German clinical research projects conducted are largely underreported. Barriers to successful publication need to be identified and appropriate measures taken. Close monitoring of projects until publication and adequate support provided to investigators may help remedy the prevailing underreporting of research. (shrink)

The writings of English poet and mystic Thomas Traherne (1626–1674) remain a relatively underexplored reservoir. Traherne's technological context includes the invention of the telescope (1608) as well as the microscope (c. 1590). As will become evident in this article, Traherne's expositions on creation display an imagination that is adept at placing itself behind both types of lenses. This article focuses on Traherne's treatment of two types of insects—the fly and the ant—in order to extrapolate some of the insights that can (...) be gleaned from Traherne's writings for the ontological status of all nonhuman animals. (shrink)

It seems worth while giving some account of this MS., because in recent years it has been said to contain certain pieces of the Moralia which it does not, and not to contain others which it does. At the foot of the first page of the text the MS. carries the pontifical shield with the arms of the Medici, and from this it is reasonable to suppose that there was a time when it belonged either to Leo X., who was (...) Pope from 1513 to 1521, or to Clement VII., who was Pope from 1523 to 1534. This being so, 1534 is established as the terminus ante quem of its writing. Towards the end of this century, about 1598, it was acquired by the Spanish Cardinal Saverio de Zelada. In 1801 the Cardinal Archbishop Antonio de Lorenzana bought in Rome a certain number of Greek and Oriental manuscripts which had formerly been in the collection of Cardinal Saverio de Zelada, and placed them in the Chapter Library at Toledo. Included with these was this MS. of the Moralia, which remains there to this day. (shrink)

El presente texto efectúa un estudio narratológico de la novela de Jorge Volpi No será la Tierra. Se analiza la estructura contradictoria del libro, la multiplicidad de tramas, el narrador polifónico, el tiempo posapocalíptico, el espacio antiutópico y desencantado y los personajes, coprotagonistas del siglo XX. Todas estas características antes mencionadas contribuyen, en el ámbito de la desterritorialización, a desalojar posturas que tienden a anquilosarse en conceptos fijos y sin movimiento, por lo que los distintos rasgos narratológicos en las (...) novelas híbridas --aquellas que están compuestas por una yuxtaposición de subgéneros-- siempre estarán emparentados con las nociones de heterogeneidad, diversidad y pluralidad, en el marco de la caída de los grandes relatos del siglo XX. This text makes a narrative study of the novel by Jorge Volpi No será la Tierra.We analyze the contradictory structure of the book, the multiple frames, the polyphonic narrator, the post-apocalyptic time, the antiutopic and disenchanted space, and the characters, co-protagonists of the twentieth century. All these features contribute, in the field of deterritorialization, to vacate positions that tend to stiffen in fixed and motionless concepts, so that different narratologic features in hybrid novels --those that consist of a juxtaposition of subgenera-- always be related to the notions of heterogeneity, diversity and plurality, as part of the fall of the great stories of the twentieth century. (shrink)

The word pro-tasis is etymologically a near equivalent of pre-mise, pro-position, and ante-cedent—all having positional, relational connotations now totally absent in contemporary use of proposition. Taking protasis for premise, Aristotle’s statement (24a16) -/- A protasis is a sentence affirming or denying something of something…. -/- is not a definition of premise—intensionally: the relational feature is absent. Likewise, it is not a general definition of proposition—extensionally: it is too narrow. This paper explores recent literature on these issues.

It seems worth while giving some account of this MS., because in recent years it has been said to contain certain pieces of the Moralia which it does not, and not to contain others which it does. At the foot of the first page of the text the MS. carries the pontifical shield with the arms of the Medici, and from this it is reasonable to suppose that there was a time when it belonged either to Leo X., who was (...) Pope from 1513 to 1521, or to Clement VII., who was Pope from 1523 to 1534. This being so, 1534 is established as the terminus ante quem of its writing. Towards the end of this century, about 1598, it was acquired by the Spanish Cardinal Saverio de Zelada. In 1801 the Cardinal Archbishop Antonio de Lorenzana bought in Rome a certain number of Greek and Oriental manuscripts which had formerly been in the collection of Cardinal Saverio de Zelada, and placed them in the Chapter Library at Toledo. Included with these was this MS. of the Moralia, which remains there to this day. (shrink)

While ante rem structuralism offers a promising account of mathematical truth and mathematical ontology, several of the most prominent formulations of the view seem to be subject to significant difficulties involving the identity conditions of the objects they posit. In this paper I argue that those difficulties can be overcome by adopting encoding structuralism, a version of realism about mathematical objects developed by Bernard Linsky, Uri Nodelman and Edward Zalta.

ABSTRACT In the following text we aim to present a proposal of interpretation of Hobbes's work from sociobiology viewpoint. Despite the fact it may strike some at first as an anachronism or straightforward wrong, reading the philosopher of Mamelsbury from a sociobiological perspective, can shed light on some particular aspects of his argument, particularly those referring to the construction of human nature and its influence on the modulation of the state of nature and on the justification of authority and political (...) obligation. So, Hobbes proceeds as a sociobiologist since he offers us a tale about the emergence of morality from where it didn't exist before and moves from there to a specific understanding of political authority. RESUMO No texto a seguir, pretendemos apresentar uma proposta de interpretação da obra de Hobbes a partir de sociobiologia. Apesar de poder chocar alguns em primeiro lugar como um anacronismo ou errado, ler o filósofo da Mamelsbury a partir de uma perspectiva sociobiológica pode lançar luz sobre alguns aspectos particulares do seu argumento, em especial os referentes à construção da natureza humana e sua influência sobre a modulação do estado de natureza e sobre a justificação da autoridade e obrigação política. Portanto, Hobbes procede como um sociobiólogo, já que ele nos oferece um conto sobre o surgimento da moralidade de onde ela não existia antes e se move de lá para uma compreensão específica da autoridade política. (shrink)

Sinopsis: El estoicismo es una escuela filosófica de la Antigua Grecia. Aunque han pasado más de dos mil años desde su nacimiento, su importancia y utilidad perduran hasta hoy. Vivimos en una sociedad compleja, llena de incertidumbre y acelerada. El estoicismo nos ayuda a aprender a guiarnos por la razón ante los contratiempos y las emociones que tendremos que enfrentar. Descubre cómo mejorar en tu vida personal y profesional de manera sencilla y demostrada.

I address questions about values in model-making in engineering, specifically: Might the role of values be attributable solely to interests involved in specifying and using the model? Selected examples illustrate the surprisingly wide variety of things one must take into account in the model-making itself. The notions of system , and physically similar systems are important and powerful in determining what is relevant to an engineering model. Another example illustrates how an idea to completely re-characterize, or reframe, an engineering problem (...) arose during model-making.I employ a qualitative analogue of the notion of physically similar systems. Historical cases can thus be drawn upon; I illustrate with a comparison between a geoengineering proposal to inject, or spray, sulfate aerosols, and two different historical cases involving the spraying of DDT . The current geoengineering proposal is seen to be like the disastrous and counterproductive case, and unlike the successful case, of the spraying of DDT. I conclude by explaining my view that model-making in science is analogous to moral perception in action, drawing on a view in moral theory that has come to be called moral particularism. (shrink)

La interpretación literaria de las últimas décadas refleja ante todo un agotamiento de la posmodernidad. La crítica a la metamorfoseada herencia de la Ilustración no ofrece nada nuevo desde hace lustros. La teoría literaria difundida durante los últimos años se manifiesta como un estertor de la retórica posmoderna que nos sitúa una y otra vez en el mismo callejón sin salida. Las «musas de la ira» parecen haber conducido la investigación sobre literatura, cultura, problemas intelectuales y políticos, hacia una guerra (...) ideológica contra la imagen de Occidente, y contra las Ideas de Ciencia y Razón, que a día de hoy es ya completamente improductiva. El problema de los falsos problemas es que exigen soluciones también falsas. A partir del Materialismo Filosófico construido por el filósofo español Gustavo Bueno, este libro expone una nueva y diferente Teoría de la Literatura, de naturaleza racionalista, científica, crítica y dialéctica, cuyo fin es la interpretación de las Ideas objetivadas formalmente en los materiales literarios. La Teoría de la Literatura será, en suma, el conocimiento científico y racional de estos materiales literarios. Y su fin es demostrar que la Literatura es inteligible, como obra que brota de la razón humana, que se abre camino hacia la libertad a través de la lucha y el enfrentamiento dialéctico, y que se desarrolla a través de un proceso comunicativo de dimensiones históricas, geográficas y políticas. (shrink)

In his elegiacs Ovid did not permit the elision of the final syllable of an iambic word ‘in an arsis , i.e. first syllable of dactyl or spondee.’ See L. Müller, De re metrica, ed. 2, p. 341. These two are the only lines in which this rule is transgressed, for in Trist. II. 296, which used to appear asstat Venus Vltori iuncta, uir ante foreswas brilliantly restored conjecturally by Bentley, and has since been found to be the actual reading (...) of our best manuscript, the Marcianus. The soundness of the text in the two lines obelized above is still open to question. (shrink)

A veces suceden cosas altamente traumáticas que cambian drásticamente nuestra vida, intuitivamente pensamos que ante tales circunstancias nos encontramos indefensos y que nuestra vida debe cambiar para peor, pero no necesariamente es así. Desde el siglo XIX en que surge el interés por el concepto de trauma, se entiende éste como una experiencia psicológicamente extrema, desbordante y desestabilizadora para cualquier persona. Las reacciones serían crisis de ansiedad, sintomatología depresiva e incluso cuadros de estrés postraumático.

The critical remark within the framework of the panel discussion problematizes three provisions of the article proposed for discussion. The first is the dual nature of the concept of “scientific progress”, which is both descriptive and normative. The remark criticizes the descriptive understanding of scientific progress and argues for the adequacy of the description of this concept exclusively in a normative way. The second provision concerns the possibility of accepting “rationality” as a universal criterion for scientific progress. The doubt about (...) the applicability of this criterion to the assessment of the achievements of scientific knowledge in general is asserted and substantiated, at the same time, the application of this criterion to particular sciences seems possible. The third provision is the uniqueness of the historical situation in which science found itself at the end of the XX century, when disciplinary separation becomes an obstacle to the study of complex objects. The uniqueness of this historical situation is disputed, as an alternative view it is argued that the attitude to the phenomenon of specialization of science from the moment of its appearance was ambivalent. Separately, the need to consider the extensive historical experience of creating various epistemological platforms to overcome disciplinary separation is stipulated. A proposal is made to further study and clarification of the possible advantages of French historical epistemology as a platform for the formation of new interdisciplinary areas of research over competing platforms (ANT, STS, strong programme of SSK). (shrink)

Ante estas obras de Victoria Diehl es fácil pensar en conocidos modelos anatómicos en cera o en la iconografía de Venus y Evas de las que un vistazo rápido a cualquier libro de historia del arte nos mostraría múltiples variantes. Algo de todo ello hay aquí. Pero también hay algo que hace que los espectadores se detengan a pensar. Algo más allá de lo reconocible que hace que las lenguas del pasado se muevan a un ritmo actual. Hermes, al trasladar (...) sus mensajes los interpreta, los adapta al interlocutor y al medio; los transforma, los traduce, los recrea. Y logra ponernos en movimiento. [...]. (shrink)

This paper deals with Marcel’s thought about the subject of death. It wants to elucidate a matter that has a preferential place in Marcel’Philosophy and Theatre. The mystery of death is for Marcel the key to understanding the image we have of the human being.

O presente texto é uma tradução da Introdução redigida por Gianni Vattimo à sua tradução para o italiano do magnum opus de Hans-Georg Gadamer, Verdade e Método. A tradução de Vattimo da obra de Gadamer foi, dentre todas as línguas, a primeira a ser realizada, e contou com a assistência do próprio autor em questões pertinentes ao processo tradutivo. Devido à primazia e à notória importância de tal tradução, sua Introdução,publicada originalmente em 1972, possui relevante mérito, constituindo verdadeiro marco nos (...) estudos da filosofia de Gadamer. Do ponto de vista material, o texto versa principalmente sobre a posição do pensamento de Gadamer ante a tradição filosófica, sobretudo em relação ao contexto contemporâneo; ao situar a filosofia de Gadamer, fornece uma abertura interpretativa fiel e sagaz ao seu pensamento. (shrink)

Sayda Piskoposu Rahip Pavlus Antâkî’nin Hıristiyan Mezheplerinin inanç esaslarını konu edinen risalesinin el yazması, Saint Petersburg’daki Rusya Bilimler Akademisi, Doğu Yazmalar Enstitüsü Kütüphanesinde bulunmaktadır. Envanter nosu B1218 olup 1b-9b arası varaklarda yer almaktadır. Çevirisi yapılan risalede, İslam’ın kutsal kitabı olan Kur’an-ı Kerim’den hareketle Hıristiyanlığı ve onun teolojisini açıklanmakta ve Müslümanların Hıristiyanlık anlayışı eleştirilmektedir. Risale, Hıristiyan teolojisinin esası olan teoloji, kristoloji ve marioloji konularını içermektedir. Ortaçağda İbn Teymiyye’nin “el-Cevabu’s-sahih limen beddele dine’l-Mesih” ismiyle reddiye yazdığı Sayda Piskoposu Rahip Pavlus Antakî tarafından kaleme (...) alınan apolojik risalede, Müslümanların Hıristiyan teolojisi başta olmak üzere çeşitli konulardaki görüşleri eleştirilmekte ve Melkiyye yaklaşımından hareketle Hıristiyanlığın temel doktrini açıklanmaya ve savunulmaya çalışılmaktadır. (shrink)

The author presents and defends three theses: (1) "the first is that it is not profitable for us at present to do moral philosophy; that should be laid aside at any rate until we have an adequate philosophy of psychology." (2) "the second is that the concepts of obligation, And duty... And of what is morally right and wrong, And of the moral sense of 'ought', Ought to be jettisoned if this is psychologically possible...." (3) "the third thesis is that (...) the differences between the well-Known english writers on moral philosophy from sidgwick to the present day are of little importance." (staff). (shrink)

This book offers an introduction to the Sophists of fifth-century Athens and a new overall interpretation of their thought. Since Plato first animadverted on their activities, the Sophists have commonly been presented as little better than intellectual mountebanks - a picture which Professor Kerferd forcefully challenges here. Interpreting the evidence with care, he shows them to have been part of an exciting and historically crucial intellectual movement. At the centre of their teaching was a form of relativism, most famously expressed (...) by Protagoras as 'Man is the measure of all things', and which they developed in a wide range of views - on knowledge and argument, virtue, government, society, and the gods. On all these subjects the Sophists did far more than simply provoke Plato to thought. Their contributions were substantial and serious; they inaugurated the debate on many central philosophical questions and decisively shifted the focus of philosophical attention from the cosmos to man. (shrink)

Kindī, d. ca. 873; terminology; philosophy, Islamic; dictionaries.

An examination of verbal hallucinations and thought insertion as examples of "alienated self-consciousness.".

This book traces the intellectual revolution initiated by Thales in the sixth century BC to its culmination in the metaphysics of Parmenides.

This entirely new work guides the reader through the most basic systems of modal propositional logic up to systems of modal predicate with identity, dealing with both technical developments and discussing philosophical applications.